alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid has been researched along with Substance Withdrawal Syndrome in 7 studies
alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid: An IBOTENIC ACID homolog and glutamate agonist. The compound is the defining agonist for the AMPA subtype of glutamate receptors (RECEPTORS, AMPA). It has been used as a radionuclide imaging agent but is more commonly used as an experimental tool in cell biological studies.
Substance Withdrawal Syndrome: Physiological and psychological symptoms associated with withdrawal from the use of a drug after prolonged administration or habituation. The concept includes withdrawal from smoking or drinking, as well as withdrawal from an administered drug.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Triadimefon (TDF) is a triazole fungicide that blocks the reuptake of dopamine (DA) and leads to increased locomotor activity levels in mice and rats, effects similar to those of indirect DA agonists such as cocaine." | 1.32 | Development of behavioral sensitization to the cocaine-like fungicide triadimefon is prevented by AMPA, NMDa, DA D1 but not DA D2 receptor antagonists. ( Cory-Slechta, DA; Reeves, R; Thiruchelvam, M, 2004) |
| "Caroverine is a class B calcium-channel-blocker and antiglutamatergic agent with significant effects on the brain function." | 1.30 | Infusional high-dose application of the calcium-channel-blocking and antiglutamatergic agent caroverine in the treatment of alcohol withdrawal (DSM-III-R 291.80). ( Fartacek, R; Geretsegger, C, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (14.29) | 18.2507 |
| 2000's | 4 (57.14) | 29.6817 |
| 2010's | 2 (28.57) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Williams, SB | 1 |
| Yorgason, JT | 1 |
| Nelson, AC | 1 |
| Lewis, N | 1 |
| Nufer, TM | 1 |
| Edwards, JG | 1 |
| Steffensen, SC | 1 |
| Shen, G | 1 |
| Tietz, EI | 1 |
| Li, HF | 1 |
| Kendig, JJ | 1 |
| Reeves, R | 1 |
| Thiruchelvam, M | 1 |
| Cory-Slechta, DA | 1 |
| Faleiro, LJ | 1 |
| Jones, S | 1 |
| Kauer, JA | 1 |
| Hendricson, AW | 1 |
| Maldve, RE | 1 |
| Salinas, AG | 1 |
| Theile, JW | 1 |
| Zhang, TA | 1 |
| Diaz, LM | 1 |
| Morrisett, RA | 1 |
| Geretsegger, C | 1 |
| Fartacek, R | 1 |
7 other studies available for alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid and Substance Withdrawal Syndrome
| Article | Year |
|---|---|
Glutamate Transmission to Ventral Tegmental Area GABA Neurons Is Altered by Acute and Chronic Ethanol.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Central Nervous System Depressant | 2018 |
Down-regulation of synaptic GluN2B subunit-containing N-methyl-D-aspartate receptors: a physiological brake on CA1 neuron α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid hyperexcitability during benzodiazepine withdrawal.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzodiazepines; CA1 Region, Hipp | 2011 |
Ethanol withdrawal hyper-responsiveness mediated by NMDA receptors in spinal cord motor neurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cyclic AMP-Dependent Protein Kina | 2003 |
Development of behavioral sensitization to the cocaine-like fungicide triadimefon is prevented by AMPA, NMDa, DA D1 but not DA D2 receptor antagonists.
Topics: 3,4-Dihydroxyphenylacetic Acid; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; B | 2004 |
Rapid synaptic plasticity of glutamatergic synapses on dopamine neurons in the ventral tegmental area in response to acute amphetamine injection.
Topics: 2-Amino-5-phosphonovalerate; Age Factors; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; | 2004 |
Aberrant synaptic activation of N-methyl-D-aspartate receptors underlies ethanol withdrawal hyperexcitability.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Blotting, Western; Central Nervou | 2007 |
Infusional high-dose application of the calcium-channel-blocking and antiglutamatergic agent caroverine in the treatment of alcohol withdrawal (DSM-III-R 291.80).
Topics: Adult; Alcohols; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Calcium Channel Blockers; | 1998 |