alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid has been researched along with Spinal Cord Injuries in 5 studies
alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid: An IBOTENIC ACID homolog and glutamate agonist. The compound is the defining agonist for the AMPA subtype of glutamate receptors (RECEPTORS, AMPA). It has been used as a radionuclide imaging agent but is more commonly used as an experimental tool in cell biological studies.
Spinal Cord Injuries: Penetrating and non-penetrating injuries to the spinal cord resulting from traumatic external forces (e.g., WOUNDS, GUNSHOT; WHIPLASH INJURIES; etc.).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Upper cervical spinal cord injuries (SCI) disrupt descending inputs to phrenic motor neurons (PhMNs), impairing respiratory function." | 1.72 | Cervical spinal hemisection alters phrenic motor neuron glutamatergic mRNA receptor expression. ( Mantilla, CB; Rana, S; Sieck, GC; Zhan, WZ, 2022) |
| "At the cellular level, spasticity is considered to be primarily caused by the hyperexcitability of spinal α-motoneurons (MNs) within the spinal stretch reflex circuit." | 1.72 | Molecular Identification of Pro-Excitogenic Receptor and Channel Phenotypes of the Deafferented Lumbar Motoneurons in the Early Phase after SCT in Rats. ( Ji, B; Skup, M; Wojtaś, B, 2022) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (40.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 2 (40.00) | 2.80 |
| Authors | Studies |
|---|---|
| Rana, S | 1 |
| Zhan, WZ | 1 |
| Sieck, GC | 1 |
| Mantilla, CB | 1 |
| Ji, B | 1 |
| Wojtaś, B | 1 |
| Skup, M | 1 |
| Garraway, SM | 1 |
| Anderson, AJ | 1 |
| Mendell, LM | 1 |
| Wrathall, JR | 1 |
| Teng, YD | 1 |
| Choiniere, D | 1 |
| Agrawal, SK | 1 |
| Fehlings, MG | 1 |
5 other studies available for alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid and Spinal Cord Injuries
| Article | Year |
|---|---|
Cervical spinal hemisection alters phrenic motor neuron glutamatergic mRNA receptor expression.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cervical Cord; Diaphragm; In Situ | 2022 |
Molecular Identification of Pro-Excitogenic Receptor and Channel Phenotypes of the Deafferented Lumbar Motoneurons in the Early Phase after SCT in Rats.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Chlorides; gamma-Aminobutyric Aci | 2022 |
BDNF-induced facilitation of afferent-evoked responses in lamina II neurons is reduced after neonatal spinal cord contusion injury.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Afferent Pathways; Age Factors; alpha-Amino-3-hydroxy-5-methyl | 2005 |
Amelioration of functional deficits from spinal cord trauma with systemically administered NBQX, an antagonist of non-N-methyl-D-aspartate receptors.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Behavior, Animal; Female; Quinoxa | 1996 |
Role of NMDA and non-NMDA ionotropic glutamate receptors in traumatic spinal cord axonal injury.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Axons; Cobalt; Excitatory Amino A | 1997 |