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alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid and Seizures, Febrile

alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid has been researched along with Seizures, Febrile in 1 studies

alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid: An IBOTENIC ACID homolog and glutamate agonist. The compound is the defining agonist for the AMPA subtype of glutamate receptors (RECEPTORS, AMPA). It has been used as a radionuclide imaging agent but is more commonly used as an experimental tool in cell biological studies.

Seizures, Febrile: Seizures that occur during a febrile episode. It is a common condition, affecting 2-5% of children aged 3 months to five years. An autosomal dominant pattern of inheritance has been identified in some families. The majority are simple febrile seizures (generally defined as generalized onset, single seizures with a duration of less than 30 minutes). Complex febrile seizures are characterized by focal onset, duration greater than 30 minutes, and/or more than one seizure in a 24 hour period. The likelihood of developing epilepsy (i.e., a nonfebrile seizure disorder) following simple febrile seizures is low. Complex febrile seizures are associated with a moderately increased incidence of epilepsy. (From Menkes, Textbook of Child Neurology, 5th ed, p784)

Research Excerpts

ExcerptRelevanceReference
"Jujuboside B (JuB) is a main bioactive saponin component isolated from the Chinese anti-insomnia herbal medicine Ziziphi Spinosae Semen (ZSS), seed of Ziziphus jujuba Mill, which has been proved to exhibit neuroprotective effects recently."1.91Jujuboside B inhibits febrile seizure by modulating AMPA receptor activity. ( Bai, H; Bai, W; Chen, S; Dong, C; Guo, H; Hao, J; Huang, Z; Jia, Q; Jin, B; Kong, D; Li, Y; Qin, X; Yang, Z; Zhang, W; Zhao, J; Zhao, Z, 2023)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's1 (100.00)2.80

Authors

AuthorsStudies
Jin, B1
Bai, W1
Zhao, J1
Qin, X1
Guo, H1
Li, Y1
Hao, J1
Chen, S1
Yang, Z1
Bai, H1
Zhao, Z1
Jia, Q1
Dong, C1
Huang, Z1
Kong, D1
Zhang, W1

Other Studies

1 other study available for alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid and Seizures, Febrile

ArticleYear
Jujuboside B inhibits febrile seizure by modulating AMPA receptor activity.
    Journal of ethnopharmacology, 2023, Mar-25, Volume: 304

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; HEK293 Cells; Humans; Mice; Recep

2023