alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid has been researched along with Rett Syndrome in 2 studies
alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid: An IBOTENIC ACID homolog and glutamate agonist. The compound is the defining agonist for the AMPA subtype of glutamate receptors (RECEPTORS, AMPA). It has been used as a radionuclide imaging agent but is more commonly used as an experimental tool in cell biological studies.
Rett Syndrome: An inherited neurological developmental disorder that is associated with X-LINKED INHERITANCE and may be lethal in utero to hemizygous males. The affected female is normal until the age of 6-25 months when progressive loss of voluntary control of hand movements and communication skills; ATAXIA; SEIZURES; autistic behavior; intermittent HYPERVENTILATION; and HYPERAMMONEMIA appear. (From Menkes, Textbook of Child Neurology, 5th ed, p199)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ricceri, L | 1 |
| De Filippis, B | 1 |
| Laviola, G | 1 |
| Wenk, GL | 1 |
| Mobley, SL | 1 |
1 review available for alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid and Rett Syndrome
| Article | Year |
|---|---|
Mouse models of Rett syndrome: from behavioural phenotyping to preclinical evaluation of new therapeutic approaches.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain; Desipramine; Disease Model | 2008 |
1 other study available for alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid and Rett Syndrome
| Article | Year |
|---|---|
Choline acetyltransferase activity and vesamicol binding in Rett syndrome and in rats with nucleus basalis lesions.
Topics: Acetylcholine; Adolescent; Adult; Aging; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; A | 1996 |