alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid has been researched along with Pregnancy in 52 studies
alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid: An IBOTENIC ACID homolog and glutamate agonist. The compound is the defining agonist for the AMPA subtype of glutamate receptors (RECEPTORS, AMPA). It has been used as a radionuclide imaging agent but is more commonly used as an experimental tool in cell biological studies.
Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We aimed to assess whether lifetime exposure to glyphosate and its degradation product, aminomethylphosphonic acid (AMPA), is associated with elevated liver transaminases and metabolic syndrome among young adults." | 8.31 | Association of Lifetime Exposure to Glyphosate and Aminomethylphosphonic Acid (AMPA) with Liver Inflammation and Metabolic Syndrome at Young Adulthood: Findings from the CHAMACOS Study. ( Bradman, A; Eskenazi, B; Gunier, RB; Harley, KG; Holland, N; Kogut, K; Limbach, C; Mendez, X; Mills, PJ; Mora, AM; Perito, ER; Rauch, S, 2023) |
| "We measured urinary concentrations of glyphosate, glufosinate, and their primary metabolites aminomethylphosphonic acid (AMPA) and 3-methylphosphinicopropionic acid (3-MPPA) in a single spot urine specimen collected during the first trimester of pregnancy from the Maternal-Infant Research on Environmental Chemicals (MIREC) study." | 4.31 | Urinary concentrations and determinants of glyphosate and glufosinate in pregnant Canadian participants in the MIREC study. ( Arbuckle, TE; Ashley-Martin, J; Bienvenu, JF; Borghese, MM; Bouchard, MF; Brion, O; Fisher, M; Foster, WG; Gaudreau, E; Huang, R; Lanphear, B; MacPherson, S; Owen, J, 2023) |
| "We aimed to assess whether lifetime exposure to glyphosate and its degradation product, aminomethylphosphonic acid (AMPA), is associated with elevated liver transaminases and metabolic syndrome among young adults." | 4.31 | Association of Lifetime Exposure to Glyphosate and Aminomethylphosphonic Acid (AMPA) with Liver Inflammation and Metabolic Syndrome at Young Adulthood: Findings from the CHAMACOS Study. ( Bradman, A; Eskenazi, B; Gunier, RB; Harley, KG; Holland, N; Kogut, K; Limbach, C; Mendez, X; Mills, PJ; Mora, AM; Perito, ER; Rauch, S, 2023) |
| "Our purpose was to evaluate the effect of seizures on kainate and alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid receptor binding in maternal rat brain and whether maternal peripheral administration of magnesium sulfate can decrease this effect." | 3.70 | Magnesium prevents seizure-induced reduction in excitatory amino acid receptor (kainate and alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid) binding in pregnant rat brain. ( Custodio, D; Hallak, M; Hotra, JW; Kruger, ML, 2000) |
| " In contrast, neither QA up to 5 mM nor trans-ACPD had a significant toxic effect in either KCl group." | 1.30 | NMDA and non-NMDA receptor-mediated excitotoxicity are potentiated in cultured striatal neurons by prior chronic depolarization. ( Chen, Q; Reiner, A; Surmeier, DJ, 1999) |
| "Pregnancy is associated with a significant alteration of NMDA and non-NMDA receptor binding in rats." | 1.30 | N-methyl-D-aspartate receptor binding is altered and seizure potential reduced in pregnant rats. ( Standley, CA, 1999) |
| " At a concentration that was not toxic by itself, L-trans-pyrrolidine-2,4-dicarboxylate increased the toxicity of glutamate approximately fivefold and slowed the clearance of glutamate from the extracellular space." | 1.29 | Inhibition of glutamate uptake with L-trans-pyrrolidine-2,4-dicarboxylate potentiates glutamate toxicity in primary hippocampal cultures. ( Buchhalter, JR; Djali, S; Robinson, MB, 1993) |
| "Phencyclidine (PCP), which was without effect on QA- and KA-evoked GABA release, inhibited the Glu response by about 50%." | 1.28 | Complex interaction between quisqualate and kainate receptors as revealed by measurement of GABA release from striatal neurons in primary culture. ( Bockaert, J; Pin, JP; Van Vliet, BJ, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (1.92) | 18.7374 |
| 1990's | 20 (38.46) | 18.2507 |
| 2000's | 17 (32.69) | 29.6817 |
| 2010's | 8 (15.38) | 24.3611 |
| 2020's | 6 (11.54) | 2.80 |
| Authors | Studies |
|---|---|
| Sun, W | 1 |
| Yang, Y | 1 |
| Chen, X | 1 |
| Mei, Y | 1 |
| Li, X | 1 |
| An, L | 1 |
| Mishra, A | 1 |
| Singla, R | 1 |
| Kumar, R | 1 |
| Sharma, A | 1 |
| Joshi, R | 1 |
| Sarma, P | 1 |
| Kaur, G | 1 |
| Prajapat, M | 1 |
| Bhatia, A | 1 |
| Medhi, B | 1 |
| Ashley-Martin, J | 3 |
| Huang, R | 3 |
| MacPherson, S | 3 |
| Brion, O | 3 |
| Owen, J | 3 |
| Gaudreau, E | 3 |
| Bienvenu, JF | 3 |
| Fisher, M | 3 |
| Borghese, MM | 3 |
| Bouchard, MF | 3 |
| Lanphear, B | 3 |
| Foster, WG | 3 |
| Arbuckle, TE | 3 |
| Eskenazi, B | 1 |
| Gunier, RB | 1 |
| Rauch, S | 1 |
| Kogut, K | 1 |
| Perito, ER | 1 |
| Mendez, X | 1 |
| Limbach, C | 1 |
| Holland, N | 1 |
| Bradman, A | 1 |
| Harley, KG | 1 |
| Mills, PJ | 1 |
| Mora, AM | 1 |
| Gerace, E | 1 |
| Curti, L | 1 |
| Caffino, L | 1 |
| Bigagli, E | 1 |
| Mottarlini, F | 1 |
| Castillo Díaz, F | 1 |
| Ilari, A | 1 |
| Luceri, C | 1 |
| Dani, C | 1 |
| Fumagalli, F | 1 |
| Masi, A | 1 |
| Mannaioni, G | 1 |
| Habib, MZ | 1 |
| Elnahas, EM | 1 |
| Aboul-Ela, YM | 1 |
| Ebeid, MA | 1 |
| Tarek, M | 1 |
| Sadek, DR | 1 |
| Negm, EA | 1 |
| Abdelhakam, DA | 1 |
| Aboul-Fotouh, S | 1 |
| Gulchina, Y | 1 |
| Xu, SJ | 1 |
| Snyder, MA | 1 |
| Elefant, F | 1 |
| Gao, WJ | 1 |
| Nelson-Mora, J | 1 |
| Escobar, ML | 1 |
| Rodríguez-Durán, L | 1 |
| Massieu, L | 1 |
| Montiel, T | 1 |
| Rodríguez, VM | 1 |
| Hernández-Mercado, K | 1 |
| Gonsebatt, ME | 1 |
| McNair, LF | 1 |
| Kohlmeier, KA | 1 |
| Takeuchi, K | 1 |
| Yoshii, K | 1 |
| Pilarski, JQ | 2 |
| Fregosi, RF | 2 |
| Jantas, D | 1 |
| Jaworska-Feil, L | 1 |
| Lipkowski, AW | 1 |
| Lason, W | 1 |
| Wright, CL | 1 |
| McCarthy, MM | 1 |
| Schapansky, J | 1 |
| Morissette, M | 1 |
| Odero, G | 1 |
| Albensi, B | 1 |
| Glazner, G | 1 |
| Zhang, YH | 1 |
| Wang, XM | 1 |
| Ennis, M | 1 |
| Matteucci, A | 1 |
| Cammarota, R | 1 |
| Paradisi, S | 1 |
| Varano, M | 1 |
| Balduzzi, M | 1 |
| Leo, L | 1 |
| Bellenchi, GC | 1 |
| De Nuccio, C | 1 |
| Carnovale-Scalzo, G | 1 |
| Scorcia, G | 1 |
| Frank, C | 1 |
| Mallozzi, C | 1 |
| Di Stasi, AM | 1 |
| Visentin, S | 1 |
| Malchiodi-Albedi, F | 1 |
| El-Sayed, M | 1 |
| Hofman-Bang, J | 1 |
| Mikkelsen, JD | 1 |
| Walcott, EC | 1 |
| Higgins, EA | 1 |
| Desai, NS | 1 |
| Jaiswal, SJ | 1 |
| Harrison, CM | 1 |
| Poluch, S | 1 |
| König, N | 1 |
| Colonnese, MT | 1 |
| Shi, J | 1 |
| Constantine-Paton, M | 1 |
| Metzler, M | 1 |
| Li, B | 1 |
| Gan, L | 1 |
| Georgiou, J | 1 |
| Gutekunst, CA | 1 |
| Wang, Y | 1 |
| Torre, E | 1 |
| Devon, RS | 1 |
| Oh, R | 1 |
| Legendre-Guillemin, V | 1 |
| Rich, M | 1 |
| Alvarez, C | 1 |
| Gertsenstein, M | 1 |
| McPherson, PS | 1 |
| Nagy, A | 1 |
| Wang, YT | 1 |
| Roder, JC | 1 |
| Raymond, LA | 1 |
| Hayden, MR | 1 |
| Poulsen, CF | 1 |
| Simeone, TA | 1 |
| Maar, TE | 1 |
| Smith-Swintosky, V | 1 |
| White, HS | 1 |
| Schousboe, A | 2 |
| El-Khodor, BF | 1 |
| Flores, G | 1 |
| Srivastava, LK | 1 |
| Boksa, P | 1 |
| Lemaire, V | 1 |
| Billard, JM | 1 |
| Dutar, P | 1 |
| George, O | 1 |
| Piazza, PV | 1 |
| Epelbaum, J | 1 |
| Le Moal, M | 1 |
| Mayo, W | 1 |
| Tseng, KY | 1 |
| Lewis, BL | 1 |
| Lipska, BK | 1 |
| O'Donnell, P | 1 |
| Sato, Y | 1 |
| Nakanishi, K | 1 |
| Tokita, Y | 1 |
| Kakizawa, H | 1 |
| Ida, M | 1 |
| Maeda, H | 1 |
| Matsui, F | 1 |
| Aono, S | 1 |
| Saito, A | 1 |
| Kuroda, Y | 1 |
| Hayakawa, M | 1 |
| Kojima, S | 1 |
| Oohira, A | 1 |
| Chen, Q | 2 |
| Harris, C | 1 |
| Brown, CS | 1 |
| Howe, A | 1 |
| Surmeier, DJ | 2 |
| Reiner, A | 2 |
| Robinson, MB | 1 |
| Djali, S | 1 |
| Buchhalter, JR | 1 |
| Lovinger, DM | 1 |
| Reichling, DB | 1 |
| MacDermott, AB | 1 |
| Freund, WD | 1 |
| Reddig, S | 1 |
| Caner, H | 1 |
| Collins, JL | 1 |
| Harris, SM | 1 |
| Kassell, NF | 1 |
| Lee, KS | 1 |
| Bowie, D | 1 |
| Smart, TG | 1 |
| Hori, Y | 1 |
| Kanda, K | 1 |
| Durkin, JP | 1 |
| Tremblay, R | 1 |
| Chakravarthy, B | 1 |
| Mealing, G | 1 |
| Morley, P | 1 |
| Small, D | 1 |
| Song, D | 1 |
| Fryer, HJ | 1 |
| Knox, RJ | 1 |
| Strittmatter, SM | 1 |
| Kalb, RG | 1 |
| Kim, EY | 1 |
| Koh, JY | 1 |
| Kim, YH | 1 |
| Sohn, S | 1 |
| Joe, E | 1 |
| Gwag, BJ | 1 |
| Standley, CA | 1 |
| Maric, D | 1 |
| Liu, QY | 1 |
| Grant, GM | 1 |
| Andreadis, JD | 1 |
| Hu, Q | 1 |
| Chang, YH | 1 |
| Barker, JL | 1 |
| Joseph, J | 1 |
| Stenger, DA | 1 |
| Ma, W | 1 |
| Hallak, M | 1 |
| Hotra, JW | 1 |
| Custodio, D | 1 |
| Kruger, ML | 1 |
| Panigrahy, A | 1 |
| Rosenberg, PA | 1 |
| Assmann, S | 1 |
| Foley, EC | 1 |
| Kinney, HC | 1 |
| Schomberg, SL | 1 |
| Su, G | 1 |
| Haworth, RA | 1 |
| Sun, D | 1 |
| Lessmann, V | 1 |
| Gottmann, K | 1 |
| Lux, HD | 1 |
| Subramaniam, S | 1 |
| Donevan, SD | 1 |
| Rogawski, MA | 1 |
| Cai, NS | 1 |
| Erdö, SL | 1 |
| Martin, D | 1 |
| Savage, DD | 1 |
| Swartzwelder, HS | 1 |
| Wahl, P | 1 |
| Honoré, T | 1 |
| Drejer, J | 1 |
| Charpentier, N | 1 |
| Dumuis, A | 1 |
| Sebben, M | 1 |
| Bockaert, J | 2 |
| Pin, JP | 2 |
| Patel, AJ | 1 |
| Sanfeliu, C | 1 |
| Hunt, A | 1 |
| Van Vliet, BJ | 1 |
52 other studies available for alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid and Pregnancy
| Article | Year |
|---|---|
Prenatal cyanuric acid exposure disrupts cognitive flexibility and mGluR1-mediated hippocampal long-term depression in male rats.
Topics: Alkaline Phosphatase; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cognition; | 2022 |
Granulocyte Colony-Stimulating Factor Improved Core Symptoms of Autism Spectrum Disorder via Modulating Glutamatergic Receptors in the Prefrontal Cortex and Hippocampus of Rat Brains.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Autism Spectrum Disorder; Brain; | 2022 |
Urinary concentrations and determinants of glyphosate and glufosinate in pregnant Canadian participants in the MIREC study.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Canada; Chromatography, Liquid; Female; Gl | 2023 |
Urinary concentrations and determinants of glyphosate and glufosinate in pregnant Canadian participants in the MIREC study.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Canada; Chromatography, Liquid; Female; Gl | 2023 |
Urinary concentrations and determinants of glyphosate and glufosinate in pregnant Canadian participants in the MIREC study.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Canada; Chromatography, Liquid; Female; Gl | 2023 |
Urinary concentrations and determinants of glyphosate and glufosinate in pregnant Canadian participants in the MIREC study.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Canada; Chromatography, Liquid; Female; Gl | 2023 |
Urinary concentrations and determinants of glyphosate and glufosinate in pregnant Canadian participants in the MIREC study.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Canada; Chromatography, Liquid; Female; Gl | 2023 |
Urinary concentrations and determinants of glyphosate and glufosinate in pregnant Canadian participants in the MIREC study.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Canada; Chromatography, Liquid; Female; Gl | 2023 |
Urinary concentrations and determinants of glyphosate and glufosinate in pregnant Canadian participants in the MIREC study.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Canada; Chromatography, Liquid; Female; Gl | 2023 |
Urinary concentrations and determinants of glyphosate and glufosinate in pregnant Canadian participants in the MIREC study.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Canada; Chromatography, Liquid; Female; Gl | 2023 |
Urinary concentrations and determinants of glyphosate and glufosinate in pregnant Canadian participants in the MIREC study.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Canada; Chromatography, Liquid; Female; Gl | 2023 |
Association of Lifetime Exposure to Glyphosate and Aminomethylphosphonic Acid (AMPA) with Liver Inflammation and Metabolic Syndrome at Young Adulthood: Findings from the CHAMACOS Study.
Topics: Adolescent; Adult; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Case-Control Studies; C | 2023 |
Ethanol-induced AMPA alterations are mediated by mGLU5 receptors through miRNA upregulation in hippocampal slices.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Ethanol; Female; Fetal Alcohol Spectrum Di | 2023 |
Risperidone impedes glutamate excitotoxicity in a valproic acid rat model of autism: Role of ADAR2 in AMPA GluA2 RNA editing.
Topics: Adenosine Deaminase; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Autism Spect | 2023 |
Epigenetic mechanisms underlying NMDA receptor hypofunction in the prefrontal cortex of juvenile animals in the MAM model for schizophrenia.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Cognition Disor | 2017 |
Gestational exposure to inorganic arsenic (iAs3+) alters glutamate disposition in the mouse hippocampus and ionotropic glutamate receptor expression leading to memory impairment.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Arsenic; Dentate Gyrus; Female; G | 2018 |
Prenatal nicotine is associated with reduced AMPA and NMDA receptor-mediated rises in calcium within the laterodorsal tegmentum: a pontine nucleus involved in addiction processes.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Female; Glutamic Acid; H | 2015 |
Superoxide modifies AMPA receptors and voltage-gated K+ channels of mouse hippocampal neurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Analysis of Variance; Animals; Cells, Cult | 2008 |
Prenatal nicotine exposure alters medullary nicotinic and AMPA-mediated control of respiratory frequency in vitro.
Topics: Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newbo | 2009 |
Effects of TRH and its analogues on primary cortical neuronal cell damage induced by various excitotoxic, necrotic and apoptotic agents.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Apoptosis; Cells, Cultured; Enzym | 2009 |
Prostaglandin E2-induced masculinization of brain and behavior requires protein kinase A, AMPA/kainate, and metabotropic glutamate receptor signaling.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Cells, Cultured | 2009 |
Neuregulin beta1 enhances peak glutamate-induced intracellular calcium levels through endoplasmic reticulum calcium release in cultured hippocampal neurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain Chemistry; Calcium; Calcium | 2009 |
Effects of neonatal inflammation on descending modulation from the rostroventromedial medulla.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Analysis of Variance; Animals; Animals, Ne | 2010 |
Curcumin protects against NMDA-induced toxicity: a possible role for NR2A subunit.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Apoptosis; Blotting, Western; Cal | 2011 |
Effect of brain-derived neurotrophic factor on activity-regulated cytoskeleton-associated protein gene expression in primary frontal cortical neurons. Comparison with NMDA and AMPA.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain-Derived Neurotrophic Factor | 2011 |
Synaptic and intrinsic balancing during postnatal development in rat pups exposed to valproic acid in utero.
Topics: Abnormalities, Drug-Induced; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Fema | 2011 |
Developmental nicotine exposure alters AMPA neurotransmission in the hypoglossal motor nucleus and pre-Botzinger complex of neonatal rats.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Brain Stem; Fem | 2013 |
AMPA receptor activation induces GABA release from neurons migrating tangentially in the intermediate zone of embryonic rat neocortex.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Carrier Proteins; Cell D | 2002 |
Chronic NMDA receptor blockade from birth delays the maturation of NMDA currents, but does not affect AMPA/kainate currents.
Topics: Adaptation, Physiological; Age Factors; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; An | 2003 |
Disruption of the endocytic protein HIP1 results in neurological deficits and decreased AMPA receptor trafficking.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain; Carrier Proteins; Clathrin | 2003 |
Modulation by topiramate of AMPA and kainate mediated calcium influx in cultured cerebral cortical, hippocampal and cerebellar neurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Cerebellum; Cerebral Cor | 2004 |
Effects of birth insult and stress at adulthood on excitatory amino acid receptors in adult rat brain.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Autoradiography; Binding Sites; B | 2004 |
Motherhood-induced memory improvement persists across lifespan in rats but is abolished by a gestational stress.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Behavior, Animal; Electrophysiolo | 2006 |
Post-pubertal disruption of medial prefrontal cortical dopamine-glutamate interactions in a developmental animal model of schizophrenia.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazo | 2007 |
A highly sulfated chondroitin sulfate preparation, CS-E, prevents excitatory amino acid-induced neuronal cell death.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Caspase 3; Cell Death; Cell Survi | 2008 |
Glutamate-mediated excitotoxic death of cultured striatal neurons is mediated by non-NMDA receptors.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Basal Ganglia; Cell Death; Cells, | 1995 |
Inhibition of glutamate uptake with L-trans-pyrrolidine-2,4-dicarboxylate potentiates glutamate toxicity in primary hippocampal cultures.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Biological Transport; Cells, Cult | 1993 |
High ethanol sensitivity of recombinant AMPA-type glutamate receptors expressed in mammalian cells.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Ethanol; Female; Humans; Kainic Acid; Kidn | 1993 |
Brief calcium transients evoked by glutamate receptor agonists in rat dorsal horn neurons: fast kinetics and mechanisms.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Calcium Channels; Cells, | 1993 |
AMPA/Zn(2+)-induced neurotoxicity in rat primary cortical cultures: involvement of L-type calcium channels.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Anim | 1994 |
Attenuation of AMPA-induced neurotoxicity by a calpain inhibitor.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acid Sequence; Animals; Calpain; Cer | 1993 |
Thiocyanate ions selectively antagonize AMPA-evoked responses in Xenopus laevis oocytes microinjected with rat brain mRNA.
Topics: Alanine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain Chemistry; Cell Me | 1993 |
Developmental alterations in NMDA receptor-mediated currents in neonatal rat spinal motoneurons.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Age Factors; alpha-Amino-3-hydrox | 1996 |
Evidence that the early loss of membrane protein kinase C is a necessary step in the excitatory amino acid-induced death of primary cortical neurons.
Topics: Alkaloids; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzophenanthridines; | 1997 |
Excitotoxic death of a subset of embryonic rat motor neurons in vitro.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Anim | 1999 |
Zn2+ entry produces oxidative neuronal necrosis in cortical cell cultures.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; 6-Cyano-7-nitroquinoxaline-2,3-dione; al | 1999 |
NMDA and non-NMDA receptor-mediated excitotoxicity are potentiated in cultured striatal neurons by prior chronic depolarization.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anti-Anxiety Agents; Benzodiazepi | 1999 |
N-methyl-D-aspartate receptor binding is altered and seizure potential reduced in pregnant rats.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Conv | 1999 |
Functional ionotropic glutamate receptors emerge during terminal cell division and early neuronal differentiation of rat neuroepithelial cells.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Bromodeoxyuridine; Calcium; Cell | 2000 |
Magnesium prevents seizure-induced reduction in excitatory amino acid receptor (kainate and alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid) binding in pregnant rat brain.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Autoradiography; Brain; Female; K | 2000 |
Differential expression of glutamate receptor subtypes in human brainstem sites involved in perinatal hypoxia-ischemia.
Topics: 2-Amino-5-phosphonovalerate; Adult; Aged; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; | 2000 |
Stimulation of Na-K-2Cl cotransporter in neurons by activation of Non-NMDA ionotropic receptor and group-I mGluRs.
Topics: Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Astrocytes; Ca | 2001 |
Evans blue reduces macroscopic desensitization of non-NMDA receptor mediated currents and prolongs excitatory postsynaptic currents in cultured rat thalamic neurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Evans Blue; Female; Glutamates; I | 1992 |
1,10-Diaminodecane and 1,12-diaminododecane block NMDA receptor currents by an open channel mechanism.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cells, Cultured; Diamines; Electr | 1992 |
The effects of kainate and the glutamate agonist, AMPA, are not separable in rat neocortical cultures.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cells, Cultured; Cerebral Cortex; | 1992 |
Effects of prenatal ethanol exposure on hippocampal ionotropic-quisqualate and kainate receptors.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Autoradiography; Brain Mapping; D | 1992 |
Development of binding sites for excitatory amino acids in cultured cerebral cortex neurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Cells, Cultured; Cer | 1991 |
On concanavalin A-treated striatal neurons quisqualate clearly behaves as a partial agonist of a receptor fully activated by kainate.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Anim | 1990 |
Development and regulation of excitatory amino acid receptors involved in the release of arachidonic acid in cultured hippocampal neural cells.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Aging; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Aci | 1990 |
Complex interaction between quisqualate and kainate receptors as revealed by measurement of GABA release from striatal neurons in primary culture.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cells, Cultured; Concanavalin A; | 1989 |