Compounds > alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid
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alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid and Palsy

alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid has been researched along with Palsy in 8 studies

alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid: An IBOTENIC ACID homolog and glutamate agonist. The compound is the defining agonist for the AMPA subtype of glutamate receptors (RECEPTORS, AMPA). It has been used as a radionuclide imaging agent but is more commonly used as an experimental tool in cell biological studies.

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (25.00)18.2507
2000's2 (25.00)29.6817
2010's4 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Santa-Cruz, LD1
Tapia, R6
Netzahualcoyotzi, C1
Ramírez-Jarquín, UN1
Tovar-y-Romo, LB1
Corona, JC2
Nakamura, R2
Kamakura, K2
Kwak, S2
Hirata, A1
Nagata, N1

Other Studies

8 other studies available for alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid and Palsy

ArticleYear
Role of energy metabolic deficits and oxidative stress in excitotoxic spinal motor neuron degeneration in vivo.
    ASN neuro, 2014, Mar-12, Volume: 6, Issue:2

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Antioxidants; Cell Death; Disease

2014
Degeneration of spinal motor neurons by chronic AMPA-induced excitotoxicity in vivo and protection by energy substrates.
    Acta neuropathologica communications, 2015, May-14, Volume: 3

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Antioxidants; Ascorbic Acid; Cell

2015
Neuropathological characterization of spinal motor neuron degeneration processes induced by acute and chronic excitotoxic stimulus in vivo.
    Neuroscience, 2016, 09-07, Volume: 331

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Apoptosis; Astrocytes; Caspase 3;

2016
Delayed administration of VEGF rescues spinal motor neurons from death with a short effective time frame in excitotoxic experimental models in vivo.
    ASN neuro, 2012, Mar-27, Volume: 4, Issue:2

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Analysis of Variance; Animals; Brain-Deriv

2012
AMPA receptor activation, but not the accumulation of endogenous extracellular glutamate, induces paralysis and motor neuron death in rat spinal cord in vivo.
    Journal of neurochemistry, 2004, Volume: 89, Issue:4

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Drug Administration Routes; Excit

2004
Ca2+-permeable AMPA receptors and intracellular Ca2+ determine motoneuron vulnerability in rat spinal cord in vivo.
    Neuropharmacology, 2007, Volume: 52, Issue:5

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Calcium; Calcium Sig

2007
Late-onset selective neuronal damage in the rat spinal cord induced by continuous intrathecal administration of AMPA.
    Brain research, 1994, Aug-22, Volume: 654, Issue:2

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Antibodies, Monoclonal; Glial Fib

1994
AMPA receptor-mediated slow neuronal death in the rat spinal cord induced by long-term blockade of glutamate transporters with THA.
    Brain research, 1997, Oct-10, Volume: 771, Issue:1

    Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amin

1997