alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid has been researched along with Osteoarthritis in 1 studies
alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid: An IBOTENIC ACID homolog and glutamate agonist. The compound is the defining agonist for the AMPA subtype of glutamate receptors (RECEPTORS, AMPA). It has been used as a radionuclide imaging agent but is more commonly used as an experimental tool in cell biological studies.
Osteoarthritis: A progressive, degenerative joint disease, the most common form of arthritis, especially in older persons. The disease is thought to result not from the aging process but from biochemical changes and biomechanical stresses affecting articular cartilage. In the foreign literature it is often called osteoarthrosis deformans.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Osteoarthritis is the single greatest cause of chronic pain, has no cure, and affects 8." | 1.56 | AMPA/kainate glutamate receptor antagonists prevent posttraumatic osteoarthritis. ( Blain, EJ; Bonnet, CS; Gilbert, SJ; Mason, DJ; Williams, AS, 2020) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (100.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bonnet, CS | 1 |
| Gilbert, SJ | 1 |
| Blain, EJ | 1 |
| Williams, AS | 1 |
| Mason, DJ | 1 |
1 other study available for alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid and Osteoarthritis
| Article | Year |
|---|---|
AMPA/kainate glutamate receptor antagonists prevent posttraumatic osteoarthritis.
Topics: Adolescent; Aged; Aged, 80 and over; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Anima | 2020 |