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alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid and Necrosis

alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid has been researched along with Necrosis in 11 studies

alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid: An IBOTENIC ACID homolog and glutamate agonist. The compound is the defining agonist for the AMPA subtype of glutamate receptors (RECEPTORS, AMPA). It has been used as a radionuclide imaging agent but is more commonly used as an experimental tool in cell biological studies.

Necrosis: The death of cells in an organ or tissue due to disease, injury or failure of the blood supply.

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (18.18)18.2507
2000's8 (72.73)29.6817
2010's1 (9.09)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ramírez-Jarquín, UN1
Tapia, R1
Benachour, N1
Séralini, GE1
Jantas, D1
Jaworska-Feil, L1
Lipkowski, AW1
Lason, W1
Rego, AC1
Monteiro, NM1
Silva, AP1
Gil, J1
Malva, JO1
Oliveira, CR1
Wolf, G1
Würdig, S1
Henschke, G1
Kim, EY1
Koh, JY1
Kim, YH1
Sohn, S1
Joe, E1
Gwag, BJ1
Glazner, GW1
Mattson, MP1
Kimbro, JR1
Kelly, PJ1
Drummond, JC1
Cole, DJ1
Patel, PM1
Cheung, NS1
Beart, PM1
Pascoe, CJ1
John, CA1
Bernard, O1
Pisani, F1
Pedale, S2
Macaione, V2
Torre, V2
Oteri, G1
Avanzini, G1
Ientile, R2
Teletta, M1
Macaione, S1

Other Studies

11 other studies available for alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid and Necrosis

ArticleYear
Neuropathological characterization of spinal motor neuron degeneration processes induced by acute and chronic excitotoxic stimulus in vivo.
    Neuroscience, 2016, 09-07, Volume: 331

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Apoptosis; Astrocytes; Caspase 3;

2016
Glyphosate formulations induce apoptosis and necrosis in human umbilical, embryonic, and placental cells.
    Chemical research in toxicology, 2009, Volume: 22, Issue:1

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Apoptosis; Caspase 3; Caspase 7; Cell Line

2009
Effects of TRH and its analogues on primary cortical neuronal cell damage induced by various excitotoxic, necrotic and apoptotic agents.
    Neuropeptides, 2009, Volume: 43, Issue:5

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Apoptosis; Cells, Cultured; Enzym

2009
Mitochondrial apoptotic cell death and moderate superoxide generation upon selective activation of non-desensitizing AMPA receptors in hippocampal cultures.
    Journal of neurochemistry, 2003, Volume: 86, Issue:4

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic A

2003
Nitric oxide synthase in the brain: light and electron microscopical findings based on the NADPH-diaphorase reaction.
    Journal of neural transmission. Supplementum, 1994, Volume: 43

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acid Oxidoreductases; Animals; Brain

1994
Zn2+ entry produces oxidative neuronal necrosis in cortical cell cultures.
    The European journal of neuroscience, 1999, Volume: 11, Issue:1

    Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; 6-Cyano-7-nitroquinoxaline-2,3-dione; al

1999
Differential effects of BDNF, ADNF9, and TNFalpha on levels of NMDA receptor subunits, calcium homeostasis, and neuronal vulnerability to excitotoxicity.
    Experimental neurology, 2000, Volume: 161, Issue:2

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic A

2000
Isoflurane and pentobarbital reduce AMPA toxicity in vivo in the rat cerebral cortex.
    Anesthesiology, 2000, Volume: 92, Issue:3

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Anesthetics, Inhalation; Animals; Blood Pr

2000
Human Bcl-2 protects against AMPA receptor-mediated apoptosis.
    Journal of neurochemistry, 2000, Volume: 74, Issue:4

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Apoptosis; Cells, Cultured; DNA;

2000
Neuroprotective effects of lamotrigine and remacemide on excitotoxicity induced by glutamate agonists in isolated chick retina.
    Experimental neurology, 2001, Volume: 170, Issue:1

    Topics: Acetamides; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Chick Embryo; Dose-Re

2001
Apoptosis and necrosis occurring in excitotoxic cell death in isolated chick embryo retina.
    Journal of neurochemistry, 2001, Volume: 79, Issue:1

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Apoptosis; Blotting, Western; Cas

2001