alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid has been researched along with Learning Disabilities in 4 studies
alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid: An IBOTENIC ACID homolog and glutamate agonist. The compound is the defining agonist for the AMPA subtype of glutamate receptors (RECEPTORS, AMPA). It has been used as a radionuclide imaging agent but is more commonly used as an experimental tool in cell biological studies.
Learning Disabilities: Conditions characterized by a significant discrepancy between an individual's perceived level of intellect and their ability to acquire new language and other cognitive skills. These may result from organic or psychological conditions. Relatively common subtypes include DYSLEXIA, DYSCALCULIA, and DYSGRAPHIA.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This study used a murine model of mucopolysaccharidosis type VII (MPS VII) to test whether pathological and functional CNS defects could be corrected by expressing beta-glucuronidase via bilateral intrastriatal injection of adeno-associated virus type 5 (AAV5betagluc) vectors." | 1.34 | Adeno-associated virus type 5 reduces learning deficits and restores glutamate receptor subunit levels in MPS VII mice CNS. ( Chen, YH; Chiorini, JA; Davidson, BL; He, X; Heth, JA; Liu, G; Martins, I, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (50.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Soman, S | 1 |
| Anju, TR | 1 |
| Jayanarayanan, S | 1 |
| Antony, S | 1 |
| Paulose, CS | 1 |
| Hoy, KC | 1 |
| Huie, JR | 1 |
| Grau, JW | 1 |
| Liu, G | 1 |
| Chen, YH | 1 |
| He, X | 1 |
| Martins, I | 1 |
| Heth, JA | 1 |
| Chiorini, JA | 1 |
| Davidson, BL | 1 |
| Ossowska, K | 1 |
| Wolfarth, S | 1 |
| Schulze, G | 1 |
| Wardas, J | 1 |
| Pietraszek, M | 1 |
| Lorenc-Koci, E | 1 |
| Smiałowska, M | 1 |
| Coper, H | 1 |
4 other studies available for alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid and Learning Disabilities
| Article | Year |
|---|---|
Impaired motor learning attributed to altered AMPA receptor function in the cerebellum of rats with temporal lobe epilepsy: ameliorating effects of Withania somnifera and withanolide A.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anticonvulsants; Carbamazepine; C | 2013 |
AMPA receptor mediated behavioral plasticity in the isolated rat spinal cord.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Anim | 2013 |
Adeno-associated virus type 5 reduces learning deficits and restores glutamate receptor subunit levels in MPS VII mice CNS.
Topics: Adenoviridae; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Blotting, Western; | 2007 |
Decline in motor functions in aging is related to the loss of NMDA receptors.
Topics: Aging; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Ankle Joint; Biomarkers; B | 2001 |