alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid has been researched along with Ischemic Attack, Transient in 13 studies
alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid: An IBOTENIC ACID homolog and glutamate agonist. The compound is the defining agonist for the AMPA subtype of glutamate receptors (RECEPTORS, AMPA). It has been used as a radionuclide imaging agent but is more commonly used as an experimental tool in cell biological studies.
Ischemic Attack, Transient: Brief reversible episodes of focal, nonconvulsive ischemic dysfunction of the brain having a duration of less than 24 hours, and usually less than one hour, caused by transient thrombotic or embolic blood vessel occlusion or stenosis. Events may be classified by arterial distribution, temporal pattern, or etiology (e.g., embolic vs. thrombotic). (From Adams et al., Principles of Neurology, 6th ed, pp814-6)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Ischemia was induced by 10 min of cardiac arrest, followed by restoration of spontaneous circulation for periods of 0, 0." | 1.29 | Non-NMDA glutamate receptor binding in canine brain after global cerebral ischemia and reperfusion. ( Fiskum, G; Perry, DC; Rosenthal, RE; Wei, H, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (7.69) | 18.7374 |
| 1990's | 11 (84.62) | 18.2507 |
| 2000's | 1 (7.69) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sheardown, MJ | 1 |
| Suzdak, PD | 1 |
| Nordholm, L | 1 |
| Frank, L | 2 |
| Bruhn, T | 2 |
| Diemer, NH | 3 |
| Li, H | 1 |
| Buchan, AM | 1 |
| Bowes, MP | 1 |
| Swanson, S | 1 |
| Zivin, JA | 1 |
| Wei, H | 1 |
| Fiskum, G | 1 |
| Rosenthal, RE | 1 |
| Perry, DC | 1 |
| Gill, R | 1 |
| Lodge, D | 2 |
| Bond, A | 1 |
| O'Neill, MJ | 1 |
| Hicks, CA | 1 |
| Jones, MG | 1 |
| Weiser, T | 1 |
| Brenner, M | 1 |
| Palluk, R | 1 |
| Bechtel, WD | 1 |
| Ceci, A | 1 |
| Brambilla, A | 1 |
| Ensinger, HA | 1 |
| Sagrada, A | 1 |
| Wienrich, M | 1 |
| Ikemune, K | 1 |
| Mitani, A | 1 |
| Namba, S | 1 |
| Kataoka, K | 1 |
| Arai, T | 1 |
| Narayanan, U | 1 |
| Chi, OZ | 1 |
| Liu, X | 1 |
| Weiss, HR | 1 |
| Balchen, T | 1 |
| Westerberg, E | 1 |
| Monaghan, DT | 1 |
| Cotman, CW | 1 |
| Wieloch, T | 1 |
1 review available for alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid and Ischemic Attack, Transient
| Article | Year |
|---|---|
Pharmacology of AMPA antagonists and their role in neuroprotection.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Disease Models, Animal; Excitator | 1997 |
12 other studies available for alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid and Ischemic Attack, Transient
| Article | Year |
|---|---|
AMPA, but not NMDA, receptor antagonism is neuroprotective in gerbil global ischaemia, even when delayed 24 h.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cerebral Cortex; Dizocilpine Male | 1993 |
The effect of an AMPA antagonist (NBQX) on postischemic neuron loss and protein synthesis in the rat brain.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Astrocytes; Autoradiography; Brai | 1993 |
Treatment with an AMPA antagonist 12 hours following severe normothermic forebrain ischemia prevents CA1 neuronal injury.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anti-Anxiety Agents; Benzodiazepi | 1993 |
The AMPA antagonist LY293558 improves functional neurological outcome following reversible spinal cord ischemia in rabbits.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Blood Pressure; Ischemia; Ischemi | 1996 |
Non-NMDA glutamate receptor binding in canine brain after global cerebral ischemia and reperfusion.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Autoradiography; Brain; Cardiopul | 1996 |
Stereoselective effects-of 2,3-benzodiazepines in vivo: electrophysiology and neuroprotection studies.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzodiazepines; Electrophysiolog | 1996 |
BIIR 561 CL: a novel combined antagonist of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors and voltage-dependent sodium channels with anticonvulsive and neuroprotective properties.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anti-Anxiety Agents; Anticonvulsa | 1999 |
Functional changes of N-methyl-D-aspartic acid and alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionate channels in gerbil hippocampal CA1, in relation to postischemic enhancement of glutamate receptor-mediated responses.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Gerbillinae; Hippocampus; Ion Cha | 1999 |
Effect of AMPA on cerebral cortical oxygen balance of ischemic rat brain.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Arterial Occlusive Diseases; Brai | 2000 |
Regional cerebral protein synthesis after transient ischemia in the rat: effect of the AMPA antagonist NBQX.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Autoradiography; Brain; Ibotenic | 1992 |
The AMPA antagonist, NBQX, protects against ischemia-induced loss of cerebellar Purkinje cells.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cell Death; Ibotenic Acid; Ischem | 1992 |
Excitatory amino acid receptors and ischemic brain damage in the rat.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Autoradiography; H | 1987 |