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alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid and Idiopathic Parkinson Disease

alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid has been researched along with Idiopathic Parkinson Disease in 10 studies

alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid: An IBOTENIC ACID homolog and glutamate agonist. The compound is the defining agonist for the AMPA subtype of glutamate receptors (RECEPTORS, AMPA). It has been used as a radionuclide imaging agent but is more commonly used as an experimental tool in cell biological studies.

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (40.00)18.2507
2000's3 (30.00)29.6817
2010's1 (10.00)24.3611
2020's2 (20.00)2.80

Authors

AuthorsStudies
Kim, G1
Shin, N1
Kim, KS1
Tamura, H1
Sasaki, M1
Nakajima, S1
Nishio, R1
Saeki, N1
Katahira, M1
Tamano, H1
Takeda, A1
Pelosi, A1
Murray, TK1
Whalley, K1
Robinson, CS1
Ward, MA1
Hicks, CA1
Lodge, D1
Vandergriff, JL1
Baumbarger, P1
Siuda, E1
Gates, M1
Ogden, AM1
Skolnick, P1
Zimmerman, DM1
Nisenbaum, ES1
Bleakman, D1
O'Neill, MJ1
Galeffi, F1
Bianchi, L1
Bolam, JP1
Della Corte, L1
Calon, F1
Rajput, AH1
Hornykiewicz, O1
Bédard, PJ1
Di Paolo, T1
Ossowska, K1
Luquin, MR1
Obeso, JA1
Laguna, J1
Guillén, J1
Martínez-Lage, JM1
Klockgether, T1
Turski, L1
Svensson, TH1
Mathé, JM1
Nomikos, GG1
Schilström, B1

Reviews

2 reviews available for alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid and Idiopathic Parkinson Disease

ArticleYear
Cell-specific α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor antagonism reveals new insights in the development of parkinson's disease.
    Movement disorders : official journal of the Movement Disorder Society, 2017, Volume: 32, Issue:7

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Glutamic Acid; Humans; Parkinson Disease

2017
The role of excitatory amino acids in experimental models of Parkinson's disease.
    Journal of neural transmission. Parkinson's disease and dementia section, 1994, Volume: 8, Issue:1-2

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amphetamine; Animals; Catalepsy; Disease M

1994

Other Studies

8 other studies available for alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid and Idiopathic Parkinson Disease

ArticleYear
Galvanic vestibular stimulation down-regulated NMDA receptors in vestibular nucleus of PD model.
    Scientific reports, 2022, 11-08, Volume: 12, Issue:1

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Electric Stimulation; Parkinson D

2022
Reactive oxygen species produced by Zn
    Neurotoxicology, 2023, Volume: 95

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Dopaminergic Neurons; Edema; Hydr

2023
LY503430, a novel alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid receptor potentiator with functional, neuroprotective and neurotrophic effects in rodent models of Parkinson's disease.
    The Journal of pharmacology and experimental therapeutics, 2003, Volume: 306, Issue:2

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Ac

2003
The effect of 6-hydroxydopamine lesions on the release of amino acids in the direct and indirect pathways of the basal ganglia: a dual microdialysis probe analysis.
    The European journal of neuroscience, 2003, Volume: 18, Issue:4

    Topics: Adrenergic Agents; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid;

2003
Levodopa-induced motor complications are associated with alterations of glutamate receptors in Parkinson's disease.
    Neurobiology of disease, 2003, Volume: 14, Issue:3

    Topics: Aged; Aged, 80 and over; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Binding Sites; Bi

2003
The AMPA receptor antagonist NBQX does not alter the motor response induced by selective dopamine agonists in MPTP-treated monkeys.
    European journal of pharmacology, 1993, Apr-28, Volume: 235, Issue:2-3

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Ac

1993
Toward an understanding of the role of glutamate in experimental parkinsonism: agonist-sensitive sites in the basal ganglia.
    Annals of neurology, 1993, Volume: 34, Issue:4

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Basal Ganglia; Cycloleucine; Elec

1993
Role of excitatory amino acids in the ventral tegmental area for central actions of non-competitive NMDA-receptor antagonists and nicotine.
    Amino acids, 1998, Volume: 14, Issue:1-3

    Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Anim

1998