alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid has been researched along with Hypoxia-Ischemia, Brain in 6 studies
alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid: An IBOTENIC ACID homolog and glutamate agonist. The compound is the defining agonist for the AMPA subtype of glutamate receptors (RECEPTORS, AMPA). It has been used as a radionuclide imaging agent but is more commonly used as an experimental tool in cell biological studies.
Hypoxia-Ischemia, Brain: A disorder characterized by a reduction of oxygen in the blood combined with reduced blood flow (ISCHEMIA) to the brain from a localized obstruction of a cerebral artery or from systemic hypoperfusion. Prolonged hypoxia-ischemia is associated with ISCHEMIC ATTACK, TRANSIENT; BRAIN INFARCTION; BRAIN EDEMA; COMA; and other conditions.
| Excerpt | Relevance | Reference |
|---|---|---|
| " injections at 1-h intervals, the first dosage was given shortly after the intrastriatal injection of (S)-alpha-amino-3-hydroxy-5,7-methylisoxazole-4-propionic acid (AMPA) (2." | 1.31 | Protective effect of the antiepileptic drug candidate talampanel against AMPA-induced striatal neurotoxicity in neonatal rats. ( Banczerowski-Pelyhe, I; Gulyás-Kovács, A; Takács, J; Tarnawa, I; Világi, I, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 6 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Világi, I | 1 |
| Takács, J | 1 |
| Gulyás-Kovács, A | 1 |
| Banczerowski-Pelyhe, I | 1 |
| Tarnawa, I | 1 |
| Hossain, MA | 1 |
| Russell, JC | 1 |
| O'Brien, R | 1 |
| Laterra, J | 1 |
| Noh, MR | 1 |
| Kim, SK | 1 |
| Sun, W | 1 |
| Park, SK | 1 |
| Choi, HC | 1 |
| Lim, JH | 1 |
| Kim, IH | 1 |
| Kim, HJ | 1 |
| Kim, H | 1 |
| Eun, BL | 1 |
| Panigrahy, A | 1 |
| Rosenberg, PA | 2 |
| Assmann, S | 1 |
| Foley, EC | 1 |
| Kinney, HC | 1 |
| Follett, PL | 1 |
| Volpe, JJ | 1 |
| Jensen, FE | 1 |
| Hamann, M | 1 |
| Rossi, DJ | 1 |
| Marie, H | 1 |
| Attwell, D | 1 |
6 other studies available for alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid and Hypoxia-Ischemia, Brain
| Article | Year |
|---|---|
Protective effect of the antiepileptic drug candidate talampanel against AMPA-induced striatal neurotoxicity in neonatal rats.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Anti-Anxiety Ag | 2002 |
Neuronal pentraxin 1: a novel mediator of hypoxic-ischemic injury in neonatal brain.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Apoptosis; Brai | 2004 |
Neuroprotective effect of topiramate on hypoxic ischemic brain injury in neonatal rats.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Administration, Oral; alpha-Amino-3-hydroxy-5-methyl-4-isoxazo | 2006 |
Differential expression of glutamate receptor subtypes in human brainstem sites involved in perinatal hypoxia-ischemia.
Topics: 2-Amino-5-phosphonovalerate; Adult; Aged; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; | 2000 |
NBQX attenuates excitotoxic injury in developing white matter.
Topics: Aging; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Excitatory Amino Acid Agon | 2000 |
Knocking out the glial glutamate transporter GLT-1 reduces glutamate uptake but does not affect hippocampal glutamate dynamics in early simulated ischaemia.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Dizo | 2002 |