alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid has been researched along with Hypoglycemia in 6 studies
alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid: An IBOTENIC ACID homolog and glutamate agonist. The compound is the defining agonist for the AMPA subtype of glutamate receptors (RECEPTORS, AMPA). It has been used as a radionuclide imaging agent but is more commonly used as an experimental tool in cell biological studies.
Hypoglycemia: A syndrome of abnormally low BLOOD GLUCOSE level. Clinical hypoglycemia has diverse etiologies. Severe hypoglycemia eventually lead to glucose deprivation of the CENTRAL NERVOUS SYSTEM resulting in HUNGER; SWEATING; PARESTHESIA; impaired mental function; SEIZURES; COMA; and even DEATH.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Glucagon secretion from pancreatic alpha cells is crucial to prevent hypoglycemia." | 4.12 | Restoring glutamate receptor signaling in pancreatic alpha cells rescues glucagon responses in type 1 diabetes. ( Caicedo, A; Panzer, JK; Tamayo, A, 2022) |
| "Hypoglycemia is a common adverse event and can injure central nervous system (CNS) white matter (WM)." | 1.40 | Novel hypoglycemic injury mechanism: N-methyl-D-aspartate receptor-mediated white matter damage. ( Brown, AM; Chen, S; Evans, RD; Hamner, MA; Ransom, BR; Yang, X; Ye, ZC, 2014) |
| "Transient anoxia/hypoglycaemia in organotypic hippocampal slice cultures, a model of transient brain ischaemia, ultimately results in delayed cell death." | 1.33 | Glutamate receptor changes associated with transient anoxia/hypoglycaemia in hippocampal slice cultures. ( Alberi, S; Hakkoum, D; Muller, D; Quintana, P, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (16.67) | 18.7374 |
| 1990's | 2 (33.33) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 1 (16.67) | 24.3611 |
| 2020's | 1 (16.67) | 2.80 |
| Authors | Studies |
|---|---|
| Panzer, JK | 2 |
| Tamayo, A | 2 |
| Caicedo, A | 2 |
| Yang, X | 1 |
| Hamner, MA | 1 |
| Brown, AM | 1 |
| Evans, RD | 1 |
| Ye, ZC | 1 |
| Chen, S | 1 |
| Ransom, BR | 1 |
| Quintana, P | 1 |
| Alberi, S | 1 |
| Hakkoum, D | 1 |
| Muller, D | 1 |
| Wang, KK | 1 |
| Nath, R | 1 |
| Posner, A | 1 |
| Raser, KJ | 1 |
| Buroker-Kilgore, M | 1 |
| Hajimohammadreza, I | 1 |
| Probert A, W | 1 |
| Marcoux, FW | 1 |
| Ye, Q | 1 |
| Takano, E | 1 |
| Hatanaka, M | 1 |
| Maki, M | 1 |
| Caner, H | 1 |
| Collins, JL | 1 |
| Fergus, A | 1 |
| Lee, KS | 1 |
| Lunney, EA | 1 |
| Hays, SJ | 1 |
| Yuen, P | 1 |
| Rogers, H | 1 |
| Birch, PJ | 1 |
| Hayes, AG | 1 |
| Westerberg, E | 1 |
| Wieloch, TW | 1 |
6 other studies available for alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid and Hypoglycemia
| Article | Year |
|---|---|
Restoring glutamate receptor signaling in pancreatic alpha cells rescues glucagon responses in type 1 diabetes.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Blood Glucose; Diabetes Mellitus, | 2022 |
Restoring glutamate receptor signaling in pancreatic alpha cells rescues glucagon responses in type 1 diabetes.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Blood Glucose; Diabetes Mellitus, | 2022 |
Restoring glutamate receptor signaling in pancreatic alpha cells rescues glucagon responses in type 1 diabetes.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Blood Glucose; Diabetes Mellitus, | 2022 |
Restoring glutamate receptor signaling in pancreatic alpha cells rescues glucagon responses in type 1 diabetes.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Blood Glucose; Diabetes Mellitus, | 2022 |
Novel hypoglycemic injury mechanism: N-methyl-D-aspartate receptor-mediated white matter damage.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Brain; Calcium; Di | 2014 |
Glutamate receptor changes associated with transient anoxia/hypoglycaemia in hippocampal slice cultures.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Blotting, Weste | 2006 |
An alpha-mercaptoacrylic acid derivative is a selective nonpeptide cell-permeable calpain inhibitor and is neuroprotective.
Topics: Acrylates; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acid Sequence; Animals; C | 1996 |
Effects of hypoxia and hypoglycaemia on DC potentials recorded from the gerbil hippocampus in vitro.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain Ischemia; Cell Hypoxia; gam | 1990 |
Changes in excitatory amino acid receptor binding in the intact and decorticated rat neostriatum following insulin-induced hypoglycemia.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Brain; Caudate Nuc | 1989 |