alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid has been researched along with Heroin Dependence in 2 studies
alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid: An IBOTENIC ACID homolog and glutamate agonist. The compound is the defining agonist for the AMPA subtype of glutamate receptors (RECEPTORS, AMPA). It has been used as a radionuclide imaging agent but is more commonly used as an experimental tool in cell biological studies.
Heroin Dependence: Strong dependence or addiction, both physiological and emotional, upon HEROIN.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In the first series of experiments, dose-response curves were generated to examine the effect of CGP56433A (0." | 1.31 | The GABA(B) antagonist CGP56433A attenuates the effect of baclofen on cocaine but not heroin self-administration in the rat. ( Brebner, K; Froestl, W; Roberts, DC, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Van den Oever, MC | 1 |
| Goriounova, NA | 1 |
| Li, KW | 1 |
| Van der Schors, RC | 1 |
| Binnekade, R | 1 |
| Schoffelmeer, AN | 1 |
| Mansvelder, HD | 1 |
| Smit, AB | 1 |
| Spijker, S | 1 |
| De Vries, TJ | 1 |
| Brebner, K | 1 |
| Froestl, W | 1 |
| Roberts, DC | 1 |
2 other studies available for alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid and Heroin Dependence
| Article | Year |
|---|---|
Prefrontal cortex AMPA receptor plasticity is crucial for cue-induced relapse to heroin-seeking.
Topics: Acoustic Stimulation; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Analysis of Variance | 2008 |
The GABA(B) antagonist CGP56433A attenuates the effect of baclofen on cocaine but not heroin self-administration in the rat.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Baclofen; Benzoates; Cocaine-Rela | 2002 |