alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid has been researched along with Hereditary Optic Neuroretinopathy in 1 studies
alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid: An IBOTENIC ACID homolog and glutamate agonist. The compound is the defining agonist for the AMPA subtype of glutamate receptors (RECEPTORS, AMPA). It has been used as a radionuclide imaging agent but is more commonly used as an experimental tool in cell biological studies.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The mitochondrial genetic disorder, Leber's hereditary optic neuropathy (LHON), is caused by a mutation in MT-ND4 gene, encoding NADH dehydrogenase subunit 4." | 1.51 | Glutamate Stimulation Dysregulates AMPA Receptors-Induced Signal Transduction Pathway in Leber's Inherited Optic Neuropathy Patient-Specific hiPSC-Derived Retinal Ganglion Cells. ( Chen, SJ; Chen, WS; Chien, CS; Chiou, GY; Chiou, SH; Hsu, CC; Hwang, DK; Lin, TC; Lin, TW; Nguyen, PNN; Peng, CH; Tsai, CY; Yang, YP; Yarmishyn, AA, 2019) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yang, YP | 1 |
| Nguyen, PNN | 1 |
| Lin, TC | 1 |
| Yarmishyn, AA | 1 |
| Chen, WS | 1 |
| Hwang, DK | 1 |
| Chiou, GY | 1 |
| Lin, TW | 1 |
| Chien, CS | 1 |
| Tsai, CY | 1 |
| Chiou, SH | 1 |
| Chen, SJ | 1 |
| Peng, CH | 1 |
| Hsu, CC | 1 |
1 other study available for alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid and Hereditary Optic Neuroretinopathy
| Article | Year |
|---|---|
Glutamate Stimulation Dysregulates AMPA Receptors-Induced Signal Transduction Pathway in Leber's Inherited Optic Neuropathy Patient-Specific hiPSC-Derived Retinal Ganglion Cells.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Base Sequence; Cell Differentiation; Down- | 2019 |