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alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid and Epilepsy, Tonic-Clonic

alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid has been researched along with Epilepsy, Tonic-Clonic in 1 studies

alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid: An IBOTENIC ACID homolog and glutamate agonist. The compound is the defining agonist for the AMPA subtype of glutamate receptors (RECEPTORS, AMPA). It has been used as a radionuclide imaging agent but is more commonly used as an experimental tool in cell biological studies.

Epilepsy, Tonic-Clonic: A generalized seizure disorder characterized by recurrent major motor seizures. The initial brief tonic phase is marked by trunk flexion followed by diffuse extension of the trunk and extremities. The clonic phase features rhythmic flexor contractions of the trunk and limbs, pupillary dilation, elevations of blood pressure and pulse, urinary incontinence, and tongue biting. This is followed by a profound state of depressed consciousness (post-ictal state) which gradually improves over minutes to hours. The disorder may be cryptogenic, familial, or symptomatic (caused by an identified disease process). (From Adams et al., Principles of Neurology, 6th ed, p329)

Research Excerpts

ExcerptRelevanceReference
"02% propylthiouracil (PTU) through mother's milk showed a high incidence of audiogenic seizures after maturation."3.70[Running fit and generalized tonic-clonic seizure are differently controlled by different subtype receptors in the brainstem]. ( Higashiyama, A; Ishida, N; Kato, N; Yasuda, S, 1998)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Yasuda, S1
Ishida, N1
Higashiyama, A1
Kato, N1

Other Studies

1 other study available for alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid and Epilepsy, Tonic-Clonic

ArticleYear
[Running fit and generalized tonic-clonic seizure are differently controlled by different subtype receptors in the brainstem].
    Nihon shinkei seishin yakurigaku zasshi = Japanese journal of psychopharmacology, 1998, Volume: 18, Issue:4

    Topics: Acoustic Stimulation; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anticonvuls

1998