alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid has been researched along with Epilepsy, Absence in 4 studies
alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid: An IBOTENIC ACID homolog and glutamate agonist. The compound is the defining agonist for the AMPA subtype of glutamate receptors (RECEPTORS, AMPA). It has been used as a radionuclide imaging agent but is more commonly used as an experimental tool in cell biological studies.
Epilepsy, Absence: A seizure disorder usually occurring in childhood characterized by rhythmic electrical brain discharges of generalized onset. Clinical features include a sudden cessation of ongoing activity usually without loss of postural tone. Rhythmic blinking of the eyelids or lip smacking frequently accompanies the SEIZURES. The usual duration is 5-10 seconds, and multiple episodes may occur daily. Juvenile absence epilepsy is characterized by the juvenile onset of absence seizures and an increased incidence of myoclonus and tonic-clonic seizures. (Menkes, Textbook of Child Neurology, 5th ed, p736)
| Excerpt | Relevance | Reference |
|---|---|---|
| " The effect of kynurenic acid could be blocked by a nonconvulsive dosage of kainic acid." | 1.29 | The WAG/Rij rat model for nonconvulsive absence epilepsy: involvement of nonNMDA receptors. ( Coenen, AM; Peeters, BW; Ramakers, GM; Vossen, JM, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (50.00) | 18.2507 |
| 2000's | 2 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Russo, E | 1 |
| Citraro, R | 1 |
| De Fazio, S | 1 |
| Marra, R | 1 |
| Gitto, R | 1 |
| Chimirri, A | 1 |
| De Sarro, G | 1 |
| Di Paola, ED | 1 |
| van de Bovenkamp-Janssen, MC | 1 |
| van der Kloet, JC | 1 |
| van Luijtelaar, G | 1 |
| Roubos, EW | 1 |
| Peeters, BW | 2 |
| Ramakers, GM | 2 |
| Vossen, JM | 2 |
| Coenen, AM | 2 |
| Ellenbroek, BA | 1 |
4 other studies available for alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid and Epilepsy, Absence
| Article | Year |
|---|---|
Enhancement of anti-absence effects of ethosuximide by low doses of a noncompetitive alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor antagonist in a genetic animal model of absence epilepsy.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anticonvulsants; Cerebral Cortex; | 2008 |
NMDA-NR1 and AMPA-GluR4 receptor subunit immunoreactivities in the absence epileptic WAG/Rij rat.
Topics: Aging; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anterior Thalamic Nuclei; | 2006 |
The WAG/Rij rat model for nonconvulsive absence epilepsy: involvement of nonNMDA receptors.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anticonvulsants; Behavior, Animal | 1994 |
Interactions between NMDA and nonNMDA receptors in nonconvulsive epilepsy in the WAG/Rij inbred strain.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anticonvulsants; Electroencephalo | 1994 |