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alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid and Disease Exacerbation

alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid has been researched along with Disease Exacerbation in 5 studies

alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid: An IBOTENIC ACID homolog and glutamate agonist. The compound is the defining agonist for the AMPA subtype of glutamate receptors (RECEPTORS, AMPA). It has been used as a radionuclide imaging agent but is more commonly used as an experimental tool in cell biological studies.

Research Excerpts

ExcerptRelevanceReference
" For this purpose we conducted a dose-response study at concentrations of AMPA between 0."1.35Pattern of injury with a graded excitotoxic insult and ensuing chronic medial septal damage in the rat brain. ( Andrés, N; Batlle, M; Mahy, N; Malpesa, Y; Prats, A; Pugliese, M; Rodríguez, MJ, 2009)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (40.00)29.6817
2010's3 (60.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Santa-Cruz, LD1
Tapia, R2
Ramírez-Jarquín, UN1
Rodríguez, MJ1
Prats, A1
Malpesa, Y1
Andrés, N1
Pugliese, M1
Batlle, M1
Mahy, N1
Simmons, DA1
Mehta, RA1
Lauterborn, JC1
Gall, CM1
Lynch, G1
Oliveira, A1
Hodges, H1
Rezaie, P1

Other Studies

5 other studies available for alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid and Disease Exacerbation

ArticleYear
Role of energy metabolic deficits and oxidative stress in excitotoxic spinal motor neuron degeneration in vivo.
    ASN neuro, 2014, Mar-12, Volume: 6, Issue:2

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Antioxidants; Cell Death; Disease

2014
Neuropathological characterization of spinal motor neuron degeneration processes induced by acute and chronic excitotoxic stimulus in vivo.
    Neuroscience, 2016, 09-07, Volume: 331

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Apoptosis; Astrocytes; Caspase 3;

2016
Pattern of injury with a graded excitotoxic insult and ensuing chronic medial septal damage in the rat brain.
    Journal of neurotrauma, 2009, Volume: 26, Issue:10

    Topics: Acetylcholine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Astrocytes; Atroph

2009
Brief ampakine treatments slow the progression of Huntington's disease phenotypes in R6/2 mice.
    Neurobiology of disease, 2011, Volume: 41, Issue:2

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anti-Dyskinesia Agents; Corpus St

2011
Excitotoxic lesioning of the rat basal forebrain with S-AMPA: consequent mineralization and associated glial response.
    Experimental neurology, 2003, Volume: 179, Issue:2

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Basal Nucleus of Meynert; Calcino

2003