alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid has been researched along with Disease Exacerbation in 5 studies
alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid: An IBOTENIC ACID homolog and glutamate agonist. The compound is the defining agonist for the AMPA subtype of glutamate receptors (RECEPTORS, AMPA). It has been used as a radionuclide imaging agent but is more commonly used as an experimental tool in cell biological studies.
Excerpt | Relevance | Reference |
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" For this purpose we conducted a dose-response study at concentrations of AMPA between 0." | 1.35 | Pattern of injury with a graded excitotoxic insult and ensuing chronic medial septal damage in the rat brain. ( Andrés, N; Batlle, M; Mahy, N; Malpesa, Y; Prats, A; Pugliese, M; Rodríguez, MJ, 2009) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 2 (40.00) | 29.6817 |
2010's | 3 (60.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Santa-Cruz, LD | 1 |
Tapia, R | 2 |
Ramírez-Jarquín, UN | 1 |
Rodríguez, MJ | 1 |
Prats, A | 1 |
Malpesa, Y | 1 |
Andrés, N | 1 |
Pugliese, M | 1 |
Batlle, M | 1 |
Mahy, N | 1 |
Simmons, DA | 1 |
Mehta, RA | 1 |
Lauterborn, JC | 1 |
Gall, CM | 1 |
Lynch, G | 1 |
Oliveira, A | 1 |
Hodges, H | 1 |
Rezaie, P | 1 |
5 other studies available for alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid and Disease Exacerbation
Article | Year |
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Role of energy metabolic deficits and oxidative stress in excitotoxic spinal motor neuron degeneration in vivo.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Antioxidants; Cell Death; Disease | 2014 |
Neuropathological characterization of spinal motor neuron degeneration processes induced by acute and chronic excitotoxic stimulus in vivo.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Apoptosis; Astrocytes; Caspase 3; | 2016 |
Pattern of injury with a graded excitotoxic insult and ensuing chronic medial septal damage in the rat brain.
Topics: Acetylcholine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Astrocytes; Atroph | 2009 |
Brief ampakine treatments slow the progression of Huntington's disease phenotypes in R6/2 mice.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anti-Dyskinesia Agents; Corpus St | 2011 |
Excitotoxic lesioning of the rat basal forebrain with S-AMPA: consequent mineralization and associated glial response.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Basal Nucleus of Meynert; Calcino | 2003 |