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alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid and Cocaine Abuse

alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid has been researched along with Cocaine Abuse in 9 studies

alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid: An IBOTENIC ACID homolog and glutamate agonist. The compound is the defining agonist for the AMPA subtype of glutamate receptors (RECEPTORS, AMPA). It has been used as a radionuclide imaging agent but is more commonly used as an experimental tool in cell biological studies.

Research Excerpts

ExcerptRelevanceReference
"In the first series of experiments, dose-response curves were generated to examine the effect of CGP56433A (0."1.31The GABA(B) antagonist CGP56433A attenuates the effect of baclofen on cocaine but not heroin self-administration in the rat. ( Brebner, K; Froestl, W; Roberts, DC, 2002)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (11.11)18.2507
2000's2 (22.22)29.6817
2010's5 (55.56)24.3611
2020's1 (11.11)2.80

Authors

AuthorsStudies
Khatri, SN1
Ulangkaya, H1
Maher, EE1
Sadek, S1
Hong, M1
Woodcox, AM1
Stoops, WW1
Gipson, CD2
Selvakumar, B1
Campbell, PW1
Milovanovic, M1
Park, DJ1
West, AR1
Snyder, SH1
Wolf, ME1
Shen, HW1
Huits, M1
Kalivas, PW2
Pascoli, V1
Terrier, J1
Espallergues, J1
Valjent, E1
O'Connor, EC1
Lüscher, C1
Keralapurath, MM1
Briggs, SB1
Wagner, JJ1
Ho, SY1
Chen, CH1
Liu, TH1
Chang, HF1
Liou, JC1
Ping, A1
Xi, J1
Prasad, BM1
Wang, MH1
Kruzich, PJ1
Cornish, JL1
Duffy, P1
Brebner, K1
Froestl, W1
Roberts, DC1

Other Studies

9 other studies available for alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid and Cocaine Abuse

ArticleYear
Oxycodone withdrawal is associated with increased cocaine self-administration and aberrant accumbens glutamate plasticity in rats.
    Neuropharmacology, 2024, Jan-01, Volume: 242

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Analgesics, Opioid; Animals; Cocaine; Coca

2024
AMPA receptor upregulation in the nucleus accumbens shell of cocaine-sensitized rats depends upon S-nitrosylation of stargazin.
    Neuropharmacology, 2014, Volume: 77

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium Channels; Cocaine; Cocain

2014
Prelimbic cortex and ventral tegmental area modulate synaptic plasticity differentially in nucleus accumbens during cocaine-reinstated drug seeking.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2014, Volume: 39, Issue:5

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cocaine; Cocaine-Related Disorder

2014
Contrasting forms of cocaine-evoked plasticity control components of relapse.
    Nature, 2014, May-22, Volume: 509, Issue:7501

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cocaine; Cocaine-Related Disorder

2014
Cocaine self-administration induces changes in synaptic transmission and plasticity in ventral hippocampus.
    Addiction biology, 2017, Volume: 22, Issue:2

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; CA1 Region, Hippocampal; Cocaine;

2017
Protein kinase mζ is necessary for cocaine-induced synaptic potentiation in the ventral tegmental area.
    Biological psychiatry, 2012, Apr-15, Volume: 71, Issue:8

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzophenanthridines; Cocaine; Co

2012
Contributions of nucleus accumbens core and shell GluR1 containing AMPA receptors in AMPA- and cocaine-primed reinstatement of cocaine-seeking behavior.
    Brain research, 2008, Jun-18, Volume: 1215

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Appetitive Behavior; Behavior, Ad

2008
A role for nucleus accumbens glutamate transmission in the relapse to cocaine-seeking behavior.
    Neuroscience, 1999, Volume: 93, Issue:4

    Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-

1999
The GABA(B) antagonist CGP56433A attenuates the effect of baclofen on cocaine but not heroin self-administration in the rat.
    Psychopharmacology, 2002, Volume: 160, Issue:1

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Baclofen; Benzoates; Cocaine-Rela

2002