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alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid and Chronic Illness

alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid has been researched along with Chronic Illness in 8 studies

alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid: An IBOTENIC ACID homolog and glutamate agonist. The compound is the defining agonist for the AMPA subtype of glutamate receptors (RECEPTORS, AMPA). It has been used as a radionuclide imaging agent but is more commonly used as an experimental tool in cell biological studies.

Research Excerpts

ExcerptRelevanceReference
" Whereas MTA reduced the neuronal cell death in pilocarpine-induced status epilepticus and the size of the lesion in global but not focal ischemic brain damage, it was ineffective in preserving dopaminergic neurons of the substantia nigra in the 1-methyl-4-phenyl-1,2,3,6-tetrahydro-pyridine (MPTP)-mice model."3.80Differential neuroprotective effects of 5'-deoxy-5'-methylthioadenosine. ( Alberch, J; Ceña, V; Collon, KW; Domercq, M; Fernández-Díez, B; Franco, R; Giralt, A; Giralt, E; Gottlieb, M; Lopez, I; Martínez-Pinilla, E; Matute, C; Moreno, B; Parent, JM; Posadas, I; Sánchez-Gómez, MV; Teixido, M; Villoslada, P; Zhang, H, 2014)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (25.00)18.2507
2000's3 (37.50)29.6817
2010's3 (37.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Moreno, B1
Lopez, I1
Fernández-Díez, B1
Gottlieb, M1
Matute, C1
Sánchez-Gómez, MV1
Domercq, M1
Giralt, A1
Alberch, J1
Collon, KW1
Zhang, H1
Parent, JM1
Teixido, M1
Giralt, E1
Ceña, V1
Posadas, I1
Martínez-Pinilla, E1
Villoslada, P1
Franco, R1
Zhang, TT1
Shen, FY1
Ma, LQ1
Wen, W1
Wang, B1
Peng, YZ1
Wang, ZR1
Zhao, X1
Cabrera-Pastor, A1
Llansola, M1
Reznikov, V1
Boix, J1
Felipo, V1
Garry, EM1
Moss, A1
Rosie, R1
Delaney, A1
Mitchell, R1
Fleetwood-Walker, SM1
Verkuyl, JM1
Hemby, SE1
Joëls, M1
Centonze, D1
Gubellini, P1
Bernardi, G1
Calabresi, P1
Kurumaji, A1
Ishimaru, M1
Toru, M1
Maddison, JE1
Watson, WE1
Dodd, PR1
Johnston, GA1

Other Studies

8 other studies available for alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid and Chronic Illness

ArticleYear
Differential neuroprotective effects of 5'-deoxy-5'-methylthioadenosine.
    PloS one, 2014, Volume: 9, Issue:3

    Topics: Acute Disease; Adrenergic Antagonists; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Ani

2014
Potentiation of synaptic transmission in Rat anterior cingulate cortex by chronic itch.
    Molecular brain, 2016, 07-29, Volume: 9, Issue:1

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Behavior, Animal; Chronic Disease

2016
Differential effects of chronic hyperammonemia on modulation of the glutamate-nitric oxide-cGMP pathway by metabotropic glutamate receptor 5 and low and high affinity AMPA receptors in cerebellum in vivo.
    Neurochemistry international, 2012, Volume: 61, Issue:1

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Blotting, Western; Chronic Diseas

2012
Specific involvement in neuropathic pain of AMPA receptors and adapter proteins for the GluR2 subunit.
    Molecular and cellular neurosciences, 2003, Volume: 24, Issue:1

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Carrier Proteins; Cell Membrane;

2003
Chronic stress attenuates GABAergic inhibition and alters gene expression of parvocellular neurons in rat hypothalamus.
    The European journal of neuroscience, 2004, Volume: 20, Issue:6

    Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Anim

2004
Impaired excitatory transmission in the striatum of rats chronically intoxicated with manganese.
    Experimental neurology, 2001, Volume: 172, Issue:2

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain; Cerebral Cortex; Chronic D

2001
Alpha-[3H]amino-3-hydroxy-5-methylisoxazole-4-propionic acid binding to human cerebral cortical membranes: minimal changes in postmortem brains of chronic schizophrenics.
    Journal of neurochemistry, 1992, Volume: 59, Issue:3

    Topics: 4-Chloromercuribenzenesulfonate; Adult; Aged; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Ac

1992
Alterations in cortical [3H]kainate and alpha-[3H]amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid binding in a spontaneous canine model of chronic hepatic encephalopathy.
    Journal of neurochemistry, 1991, Volume: 56, Issue:6

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cerebral Cortex; Chronic Disease;

1991