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alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid and Cerebellar Ataxia

alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid has been researched along with Cerebellar Ataxia in 1 studies

alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid: An IBOTENIC ACID homolog and glutamate agonist. The compound is the defining agonist for the AMPA subtype of glutamate receptors (RECEPTORS, AMPA). It has been used as a radionuclide imaging agent but is more commonly used as an experimental tool in cell biological studies.

Cerebellar Ataxia: Incoordination of voluntary movements that occur as a manifestation of CEREBELLAR DISEASES. Characteristic features include a tendency for limb movements to overshoot or undershoot a target (dysmetria), a tremor that occurs during attempted movements (intention TREMOR), impaired force and rhythm of diadochokinesis (rapidly alternating movements), and GAIT ATAXIA. (From Adams et al., Principles of Neurology, 6th ed, p90)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hashimoto, K1
Fukaya, M1
Qiao, X1
Sakimura, K1
Watanabe, M1
Kano, M1

Other Studies

1 other study available for alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid and Cerebellar Ataxia

ArticleYear
Impairment of AMPA receptor function in cerebellar granule cells of ataxic mutant mouse stargazer.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1999, Jul-15, Volume: 19, Issue:14

    Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Anim

1999