alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid has been researched along with Brain Vascular Disorders in 2 studies
alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid: An IBOTENIC ACID homolog and glutamate agonist. The compound is the defining agonist for the AMPA subtype of glutamate receptors (RECEPTORS, AMPA). It has been used as a radionuclide imaging agent but is more commonly used as an experimental tool in cell biological studies.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Stroke and head trauma are worldwide public health problems and leading causes of death and disability in humans, yet, no adequate neuroprotective treatment is available for therapy." | 1.30 | ZK200775: a phosphonate quinoxalinedione AMPA antagonist for neuroprotection in stroke and trauma. ( Dirnagl, U; Huth, A; Jacobsen, P; McDonald, F; Neuhaus, R; Ottow, E; Schneider, HH; Sheardown, M; Turski, L; Wiegand, F, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Buchan, AM | 1 |
| Lesiuk, H | 1 |
| Barnes, KA | 1 |
| Li, H | 1 |
| Huang, ZG | 1 |
| Smith, KE | 1 |
| Xue, D | 1 |
| Turski, L | 1 |
| Huth, A | 1 |
| Sheardown, M | 1 |
| McDonald, F | 1 |
| Neuhaus, R | 1 |
| Schneider, HH | 1 |
| Dirnagl, U | 1 |
| Wiegand, F | 1 |
| Jacobsen, P | 1 |
| Ottow, E | 1 |
2 other studies available for alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid and Brain Vascular Disorders
| Article | Year |
|---|---|
AMPA antagonists: do they hold more promise for clinical stroke trials than NMDA antagonists?
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anti-Anxiety Agents; Benzodiazepi | 1993 |
ZK200775: a phosphonate quinoxalinedione AMPA antagonist for neuroprotection in stroke and trauma.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cells, Cultured; Cerebrovascular | 1998 |