alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid has been researched along with Brain Damage, Chronic in 4 studies
alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid: An IBOTENIC ACID homolog and glutamate agonist. The compound is the defining agonist for the AMPA subtype of glutamate receptors (RECEPTORS, AMPA). It has been used as a radionuclide imaging agent but is more commonly used as an experimental tool in cell biological studies.
Brain Damage, Chronic: A condition characterized by long-standing brain dysfunction or damage, usually of three months duration or longer. Potential etiologies include BRAIN INFARCTION; certain NEURODEGENERATIVE DISORDERS; CRANIOCEREBRAL TRAUMA; ANOXIA, BRAIN; ENCEPHALITIS; certain NEUROTOXICITY SYNDROMES; metabolic disorders (see BRAIN DISEASES, METABOLIC); and other conditions.
| Excerpt | Relevance | Reference |
|---|---|---|
| " For this purpose we conducted a dose-response study at concentrations of AMPA between 0." | 1.35 | Pattern of injury with a graded excitotoxic insult and ensuing chronic medial septal damage in the rat brain. ( Andrés, N; Batlle, M; Mahy, N; Malpesa, Y; Prats, A; Pugliese, M; Rodríguez, MJ, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (50.00) | 18.2507 |
| 2000's | 2 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Rodríguez, MJ | 1 |
| Prats, A | 1 |
| Malpesa, Y | 1 |
| Andrés, N | 1 |
| Pugliese, M | 1 |
| Batlle, M | 1 |
| Mahy, N | 2 |
| Lecrux, C | 1 |
| Nicole, O | 1 |
| Chazalviel, L | 1 |
| Catone, C | 1 |
| Chuquet, J | 1 |
| MacKenzie, ET | 1 |
| Touzani, O | 1 |
| Bendahan, G | 1 |
| Boatell, ML | 1 |
| Bjelke, B | 1 |
| Tinner, B | 1 |
| Olson, L | 1 |
| Fuxe, K | 1 |
| Ikonomidou, C | 1 |
| Turski, L | 1 |
1 review available for alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid and Brain Damage, Chronic
| Article | Year |
|---|---|
Neurodegenerative disorders: clues from glutamate and energy metabolism.
Topics: Aging; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain Damage, Chronic; Bra | 1996 |
3 other studies available for alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid and Brain Damage, Chronic
| Article | Year |
|---|---|
Pattern of injury with a graded excitotoxic insult and ensuing chronic medial septal damage in the rat brain.
Topics: Acetylcholine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Astrocytes; Atroph | 2009 |
Spontaneously hypertensive rats are highly vulnerable to AMPA-induced brain lesions.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Blood Pressure; Brain Damage, Chr | 2007 |
Differential brain area vulnerability to long-term subcortical excitotoxic lesions.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain Damage, Chronic; Calcium; I | 1995 |