alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid has been researched along with Bipolar Disorder in 2 studies
alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid: An IBOTENIC ACID homolog and glutamate agonist. The compound is the defining agonist for the AMPA subtype of glutamate receptors (RECEPTORS, AMPA). It has been used as a radionuclide imaging agent but is more commonly used as an experimental tool in cell biological studies.
Bipolar Disorder: A major affective disorder marked by severe mood swings (manic or major depressive episodes) and a tendency to remission and recurrence.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Lithium has been the gold standard in the treatment of bipolar disorder (BPD) for 60 y." | 3.76 | A kinesin signaling complex mediates the ability of GSK-3beta to affect mood-associated behaviors. ( Blumenthal, R; Drevets, W; Du, J; Hunsberger, JG; Khairova, R; Liu, L; Machado-Vieira, R; Manji, HK; Tragon, T; Wang, Y; Wang, YT; Wei, Y, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zarate, CA | 1 |
| Machado-Vieira, R | 2 |
| Du, J | 1 |
| Wei, Y | 1 |
| Liu, L | 1 |
| Wang, Y | 1 |
| Khairova, R | 1 |
| Blumenthal, R | 1 |
| Tragon, T | 1 |
| Hunsberger, JG | 1 |
| Drevets, W | 1 |
| Wang, YT | 1 |
| Manji, HK | 1 |
2 other studies available for alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid and Bipolar Disorder
| Article | Year |
|---|---|
GSK-3: A key regulatory target for ketamine's rapid antidepressant effects mediated by enhanced AMPA to NMDA throughput.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Antidepressive Agents; Bipolar Disorder; G | 2016 |
A kinesin signaling complex mediates the ability of GSK-3beta to affect mood-associated behaviors.
Topics: Affect; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Antidepressive Agents; Bi | 2010 |