alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid has been researched along with Attention Deficit Disorder with Hyperactivity in 1 studies
alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid: An IBOTENIC ACID homolog and glutamate agonist. The compound is the defining agonist for the AMPA subtype of glutamate receptors (RECEPTORS, AMPA). It has been used as a radionuclide imaging agent but is more commonly used as an experimental tool in cell biological studies.
Attention Deficit Disorder with Hyperactivity: A behavior disorder originating in childhood in which the essential features are signs of developmentally inappropriate inattention, impulsivity, and hyperactivity. Although most individuals have symptoms of both inattention and hyperactivity-impulsivity, one or the other pattern may be predominant. The disorder is more frequent in males than females. Onset is in childhood. Symptoms often attenuate during late adolescence although a minority experience the full complement of symptoms into mid-adulthood. (From DSM-V)
| Excerpt | Relevance | Reference |
|---|---|---|
| " Most frequently reported adverse events were nausea, dizziness, and headache." | 2.77 | A translational approach to evaluate the efficacy and safety of the novel AMPA receptor positive allosteric modulator org 26576 in adult attention-deficit/hyperactivity disorder. ( Adler, LA; Cazorla, P; Kroon, RA; Schipper, J; Shahid, M; Stein, M; Szegedi, A; Tarazi, FI, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Adler, LA | 1 |
| Kroon, RA | 1 |
| Stein, M | 1 |
| Shahid, M | 1 |
| Tarazi, FI | 1 |
| Szegedi, A | 1 |
| Schipper, J | 1 |
| Cazorla, P | 1 |
1 trial available for alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid and Attention Deficit Disorder with Hyperactivity
| Article | Year |
|---|---|
A translational approach to evaluate the efficacy and safety of the novel AMPA receptor positive allosteric modulator org 26576 in adult attention-deficit/hyperactivity disorder.
Topics: Adult; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Attention; Attention Defic | 2012 |