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alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid and Attention Deficit Disorder with Hyperactivity

alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid has been researched along with Attention Deficit Disorder with Hyperactivity in 1 studies

alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid: An IBOTENIC ACID homolog and glutamate agonist. The compound is the defining agonist for the AMPA subtype of glutamate receptors (RECEPTORS, AMPA). It has been used as a radionuclide imaging agent but is more commonly used as an experimental tool in cell biological studies.

Attention Deficit Disorder with Hyperactivity: A behavior disorder originating in childhood in which the essential features are signs of developmentally inappropriate inattention, impulsivity, and hyperactivity. Although most individuals have symptoms of both inattention and hyperactivity-impulsivity, one or the other pattern may be predominant. The disorder is more frequent in males than females. Onset is in childhood. Symptoms often attenuate during late adolescence although a minority experience the full complement of symptoms into mid-adulthood. (From DSM-V)

Research Excerpts

ExcerptRelevanceReference
" Most frequently reported adverse events were nausea, dizziness, and headache."2.77A translational approach to evaluate the efficacy and safety of the novel AMPA receptor positive allosteric modulator org 26576 in adult attention-deficit/hyperactivity disorder. ( Adler, LA; Cazorla, P; Kroon, RA; Schipper, J; Shahid, M; Stein, M; Szegedi, A; Tarazi, FI, 2012)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Adler, LA1
Kroon, RA1
Stein, M1
Shahid, M1
Tarazi, FI1
Szegedi, A1
Schipper, J1
Cazorla, P1

Trials

1 trial available for alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid and Attention Deficit Disorder with Hyperactivity

ArticleYear
A translational approach to evaluate the efficacy and safety of the novel AMPA receptor positive allosteric modulator org 26576 in adult attention-deficit/hyperactivity disorder.
    Biological psychiatry, 2012, Dec-01, Volume: 72, Issue:11

    Topics: Adult; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Attention; Attention Defic

2012