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alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid and Apnea

alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid has been researched along with Apnea in 4 studies

alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid: An IBOTENIC ACID homolog and glutamate agonist. The compound is the defining agonist for the AMPA subtype of glutamate receptors (RECEPTORS, AMPA). It has been used as a radionuclide imaging agent but is more commonly used as an experimental tool in cell biological studies.

Apnea: A transient absence of spontaneous respiration.

Research Excerpts

ExcerptRelevanceReference
" We show that repeated obstructive apneas disrupt vagal feedback and trigger LTF of hypoglossal motoneuron activity and genioglossus muscle tone."3.76Identification of a novel form of noradrenergic-dependent respiratory motor plasticity triggered by vagal feedback. ( Duffin, J; Peever, J; Tadjalli, A, 2010)
" Microinjection of NMDA (1 nmol/50 nL; n = 7) or AMPA (50 pmol/50 nL; n = 4) into the comNTS produced a long lasting apnea."3.73Respiratory and autonomic responses to microinjection of NMDA and AMPA into the commissural subnucleus of the NTS of awake rats. ( Almado, CE; Machado, BH, 2005)
" Activation of NMDA receptors at the ventrolateral nucleus of the tractus solitarius with bilateral microinjection of NMDA, 39 pmol, produced a large increase in expiratory duration (+11 +/- 3 s, n = 8), and apnea during the expiratory phase of the respiratory cycle in half of the animals studied."3.69NMDA receptors are involved at the ventrolateral nucleus tractus solitarii for termination of inspiration. ( Berger, I; Gillis, RA; Kelly, M; Magee, S; McManigle, JE; Norman, WP; Panico, WH; Taveira DaSilva, AM; Vitagliano, S, 1995)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (50.00)18.2507
2000's1 (25.00)29.6817
2010's1 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Tadjalli, A1
Duffin, J1
Peever, J1
Almado, CE1
Machado, BH1
Berger, I1
Gillis, RA1
Vitagliano, S1
Panico, WH1
Magee, S1
Kelly, M1
Norman, WP1
McManigle, JE1
Taveira DaSilva, AM1
Banno, T1
Kohno, K1

Other Studies

4 other studies available for alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid and Apnea

ArticleYear
Identification of a novel form of noradrenergic-dependent respiratory motor plasticity triggered by vagal feedback.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2010, Dec-15, Volume: 30, Issue:50

    Topics: Adrenergic alpha-1 Receptor Antagonists; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; A

2010
Respiratory and autonomic responses to microinjection of NMDA and AMPA into the commissural subnucleus of the NTS of awake rats.
    Brain research, 2005, Nov-23, Volume: 1063, Issue:1

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Analysis of Variance; Animals; Apnea; Auto

2005
NMDA receptors are involved at the ventrolateral nucleus tractus solitarii for termination of inspiration.
    European journal of pharmacology, 1995, Apr-24, Volume: 277, Issue:2-3

    Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-

1995
Conformational changes of the smooth endoplasmic reticulum are facilitated by L-glutamate and its receptors in rat Purkinje cells.
    The Journal of comparative neurology, 1998, Dec-14, Volume: 402, Issue:2

    Topics: Alanine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Apnea; Bradycardia; Calc

1998