alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid has been researched along with Anterior Circulation Transient Ischemic Attack in 13 studies
alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid: An IBOTENIC ACID homolog and glutamate agonist. The compound is the defining agonist for the AMPA subtype of glutamate receptors (RECEPTORS, AMPA). It has been used as a radionuclide imaging agent but is more commonly used as an experimental tool in cell biological studies.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Ischemia was induced by 10 min of cardiac arrest, followed by restoration of spontaneous circulation for periods of 0, 0." | 1.29 | Non-NMDA glutamate receptor binding in canine brain after global cerebral ischemia and reperfusion. ( Fiskum, G; Perry, DC; Rosenthal, RE; Wei, H, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (7.69) | 18.7374 |
| 1990's | 11 (84.62) | 18.2507 |
| 2000's | 1 (7.69) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sheardown, MJ | 1 |
| Suzdak, PD | 1 |
| Nordholm, L | 1 |
| Frank, L | 2 |
| Bruhn, T | 2 |
| Diemer, NH | 3 |
| Li, H | 1 |
| Buchan, AM | 1 |
| Bowes, MP | 1 |
| Swanson, S | 1 |
| Zivin, JA | 1 |
| Wei, H | 1 |
| Fiskum, G | 1 |
| Rosenthal, RE | 1 |
| Perry, DC | 1 |
| Gill, R | 1 |
| Lodge, D | 2 |
| Bond, A | 1 |
| O'Neill, MJ | 1 |
| Hicks, CA | 1 |
| Jones, MG | 1 |
| Weiser, T | 1 |
| Brenner, M | 1 |
| Palluk, R | 1 |
| Bechtel, WD | 1 |
| Ceci, A | 1 |
| Brambilla, A | 1 |
| Ensinger, HA | 1 |
| Sagrada, A | 1 |
| Wienrich, M | 1 |
| Ikemune, K | 1 |
| Mitani, A | 1 |
| Namba, S | 1 |
| Kataoka, K | 1 |
| Arai, T | 1 |
| Narayanan, U | 1 |
| Chi, OZ | 1 |
| Liu, X | 1 |
| Weiss, HR | 1 |
| Balchen, T | 1 |
| Westerberg, E | 1 |
| Monaghan, DT | 1 |
| Cotman, CW | 1 |
| Wieloch, T | 1 |
1 review available for alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid and Anterior Circulation Transient Ischemic Attack
| Article | Year |
|---|---|
Pharmacology of AMPA antagonists and their role in neuroprotection.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Disease Models, Animal; Excitator | 1997 |
12 other studies available for alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid and Anterior Circulation Transient Ischemic Attack
| Article | Year |
|---|---|
AMPA, but not NMDA, receptor antagonism is neuroprotective in gerbil global ischaemia, even when delayed 24 h.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cerebral Cortex; Dizocilpine Male | 1993 |
The effect of an AMPA antagonist (NBQX) on postischemic neuron loss and protein synthesis in the rat brain.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Astrocytes; Autoradiography; Brai | 1993 |
Treatment with an AMPA antagonist 12 hours following severe normothermic forebrain ischemia prevents CA1 neuronal injury.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anti-Anxiety Agents; Benzodiazepi | 1993 |
The AMPA antagonist LY293558 improves functional neurological outcome following reversible spinal cord ischemia in rabbits.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Blood Pressure; Ischemia; Ischemi | 1996 |
Non-NMDA glutamate receptor binding in canine brain after global cerebral ischemia and reperfusion.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Autoradiography; Brain; Cardiopul | 1996 |
Stereoselective effects-of 2,3-benzodiazepines in vivo: electrophysiology and neuroprotection studies.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzodiazepines; Electrophysiolog | 1996 |
BIIR 561 CL: a novel combined antagonist of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors and voltage-dependent sodium channels with anticonvulsive and neuroprotective properties.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anti-Anxiety Agents; Anticonvulsa | 1999 |
Functional changes of N-methyl-D-aspartic acid and alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionate channels in gerbil hippocampal CA1, in relation to postischemic enhancement of glutamate receptor-mediated responses.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Gerbillinae; Hippocampus; Ion Cha | 1999 |
Effect of AMPA on cerebral cortical oxygen balance of ischemic rat brain.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Arterial Occlusive Diseases; Brai | 2000 |
Regional cerebral protein synthesis after transient ischemia in the rat: effect of the AMPA antagonist NBQX.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Autoradiography; Brain; Ibotenic | 1992 |
The AMPA antagonist, NBQX, protects against ischemia-induced loss of cerebellar Purkinje cells.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cell Death; Ibotenic Acid; Ischem | 1992 |
Excitatory amino acid receptors and ischemic brain damage in the rat.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Autoradiography; H | 1987 |