Page last updated: 2024-10-21

alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid and Anterior Choroidal Artery Infarction

alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid has been researched along with Anterior Choroidal Artery Infarction in 6 studies

alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid: An IBOTENIC ACID homolog and glutamate agonist. The compound is the defining agonist for the AMPA subtype of glutamate receptors (RECEPTORS, AMPA). It has been used as a radionuclide imaging agent but is more commonly used as an experimental tool in cell biological studies.

Research Excerpts

ExcerptRelevanceReference
"Transient focal cerebral ischemia was induced in male Wistar rats for 2 h using the suture occlusion technique."1.32Exogenous brain-derived neurotrophic factor prevents postischemic downregulation of [3H]muscimol binding to GABA(A) receptors in the cortical penumbra. ( Kiessling, M; Kollmar, R; Schäbitz, WR; Schwab, S; Sommer, C, 2003)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (50.00)18.2507
2000's3 (50.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Sommer, C2
Kollmar, R1
Schwab, S2
Kiessling, M1
Schäbitz, WR2
Müller, HD1
Hanumanthiah, KM1
Diederich, K1
Buchan, AM2
Lesiuk, H1
Barnes, KA1
Li, H1
Huang, ZG2
Smith, KE2
Xue, D2
Siesjö, B1
Barnes, K1
Lesiuk, HJ1
Kimbro, JR1
Kelly, PJ1
Drummond, JC1
Cole, DJ1
Patel, PM1

Other Studies

6 other studies available for alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid and Anterior Choroidal Artery Infarction

ArticleYear
Exogenous brain-derived neurotrophic factor prevents postischemic downregulation of [3H]muscimol binding to GABA(A) receptors in the cortical penumbra.
    Brain research. Molecular brain research, 2003, Mar-17, Volume: 111, Issue:1-2

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Binding, Competitive; Brain Ische

2003
Brain-derived neurotrophic factor but not forced arm use improves long-term outcome after photothrombotic stroke and transiently upregulates binding densities of excitatory glutamate receptors in the rat brain.
    Stroke, 2008, Volume: 39, Issue:3

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Autoradiography; Brain; Brain-Der

2008
AMPA antagonists: do they hold more promise for clinical stroke trials than NMDA antagonists?
    Stroke, 1993, Volume: 24, Issue:12 Suppl

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anti-Anxiety Agents; Benzodiazepi

1993
[Future treatment of stroke. Brain injury can be reduced with drugs].
    Nordisk medicin, 1993, Volume: 108, Issue:12

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Calcium Channel Blockers; Cell Death; Cere

1993
Delayed treatment with AMPA, but not NMDA, antagonists reduces neocortical infarction.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 1994, Volume: 14, Issue:2

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anti-Anxiety Agents; Benzodiazepi

1994
Isoflurane and pentobarbital reduce AMPA toxicity in vivo in the rat cerebral cortex.
    Anesthesiology, 2000, Volume: 92, Issue:3

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Anesthetics, Inhalation; Animals; Blood Pr

2000