alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid has been researched along with Anhedonia in 2 studies
alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid: An IBOTENIC ACID homolog and glutamate agonist. The compound is the defining agonist for the AMPA subtype of glutamate receptors (RECEPTORS, AMPA). It has been used as a radionuclide imaging agent but is more commonly used as an experimental tool in cell biological studies.
Anhedonia: Inability to experience pleasure due to impairment or dysfunction of normal psychological and neurobiological mechanisms. It is a symptom of many PSYCHOTIC DISORDERS (e.g., DEPRESSIVE DISORDER, MAJOR; and SCHIZOPHRENIA).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Anhedonia was induced by chronic stress in male mice and assayed by preferences for sucrose and female urine (n = 5-7 mice/group)." | 8.12 | Negative Allosteric Modulation of Gamma-Aminobutyric Acid A Receptors at α5 Subunit-Containing Benzodiazepine Sites Reverses Stress-Induced Anhedonia and Weakened Synaptic Function in Mice. ( Georgiou, P; Gould, TD; Rudolph, U; Thompson, SM; Troppoli, TA; Zanos, P, 2022) |
| "Anhedonia was induced by chronic stress in male mice and assayed by preferences for sucrose and female urine (n = 5-7 mice/group)." | 4.12 | Negative Allosteric Modulation of Gamma-Aminobutyric Acid A Receptors at α5 Subunit-Containing Benzodiazepine Sites Reverses Stress-Induced Anhedonia and Weakened Synaptic Function in Mice. ( Georgiou, P; Gould, TD; Rudolph, U; Thompson, SM; Troppoli, TA; Zanos, P, 2022) |
| "Anhedonia is a core symptom of social defeat stress (SDS)-induced depression associated with the reward system." | 1.46 | Association of social defeat stress-induced anhedonia-like symptoms with mGluR1-dependent decrease in membrane-bound AMPA-GluR1 in the mouse ventral midbrain. ( Seki, K; Yashiro, S, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Troppoli, TA | 1 |
| Zanos, P | 1 |
| Georgiou, P | 1 |
| Gould, TD | 1 |
| Rudolph, U | 1 |
| Thompson, SM | 1 |
| Yashiro, S | 1 |
| Seki, K | 1 |
2 other studies available for alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid and Anhedonia
| Article | Year |
|---|---|
Negative Allosteric Modulation of Gamma-Aminobutyric Acid A Receptors at α5 Subunit-Containing Benzodiazepine Sites Reverses Stress-Induced Anhedonia and Weakened Synaptic Function in Mice.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Anhedonia; Animals; Benzodiazepines; Femal | 2022 |
Association of social defeat stress-induced anhedonia-like symptoms with mGluR1-dependent decrease in membrane-bound AMPA-GluR1 in the mouse ventral midbrain.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Anhedonia; Animals; Glycine; Male; Mesence | 2017 |