alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid has been researched along with Amyloid Deposits in 2 studies
alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid: An IBOTENIC ACID homolog and glutamate agonist. The compound is the defining agonist for the AMPA subtype of glutamate receptors (RECEPTORS, AMPA). It has been used as a radionuclide imaging agent but is more commonly used as an experimental tool in cell biological studies.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In 2-month-old mice, no β-amyloid plaques deposition, but the presence of soluble oligomers, were found in CA1 area but not in dentate gyrus (DG)." | 1.42 | Region- and age-dependent reductions of hippocampal long-term potentiation and NMDA to AMPA ratio in a genetic model of Alzheimer's disease. ( Borsello, T; Calabresi, P; Costa, C; de Iure, A; Di Filippo, M; Ghiglieri, V; Sclip, A; Tantucci, M; Tozzi, A, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fernández-Pérez, EJ | 1 |
| Gallegos, S | 1 |
| Armijo-Weingart, L | 1 |
| Araya, A | 1 |
| Riffo-Lepe, NO | 1 |
| Cayuman, F | 1 |
| Aguayo, LG | 1 |
| Tozzi, A | 1 |
| Sclip, A | 1 |
| Tantucci, M | 1 |
| de Iure, A | 1 |
| Ghiglieri, V | 1 |
| Costa, C | 1 |
| Di Filippo, M | 1 |
| Borsello, T | 1 |
| Calabresi, P | 1 |
2 other studies available for alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid and Amyloid Deposits
| Article | Year |
|---|---|
Changes in neuronal excitability and synaptic transmission in nucleus accumbens in a transgenic Alzheimer's disease mouse model.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Alzheimer Disease; Animals; Biomarkers; Di | 2020 |
Region- and age-dependent reductions of hippocampal long-term potentiation and NMDA to AMPA ratio in a genetic model of Alzheimer's disease.
Topics: Aging; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Alzheimer Disease; Amyloid beta-Pro | 2015 |