Page last updated: 2024-10-21

alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid and Alcoholism

alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid has been researched along with Alcoholism in 2 studies

alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid: An IBOTENIC ACID homolog and glutamate agonist. The compound is the defining agonist for the AMPA subtype of glutamate receptors (RECEPTORS, AMPA). It has been used as a radionuclide imaging agent but is more commonly used as an experimental tool in cell biological studies.

Alcoholism: A primary, chronic disease with genetic, psychosocial, and environmental factors influencing its development and manifestations. The disease is often progressive and fatal. It is characterized by impaired control over drinking, preoccupation with the drug alcohol, use of alcohol despite adverse consequences, and distortions in thinking, most notably denial. Each of these symptoms may be continuous or periodic. (Morse & Flavin for the Joint Commission of the National Council on Alcoholism and Drug Dependence and the American Society of Addiction Medicine to Study the Definition and Criteria for the Diagnosis of Alcoholism: in JAMA 1992;268:1012-4)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Korpi, ER1
den Hollander, B1
Farooq, U1
Vashchinkina, E1
Rajkumar, R1
Nutt, DJ1
Hyytiä, P1
Dawe, GS1
Karpyak, VM1
Geske, JR1
Colby, CL1
Mrazek, DA1
Biernacka, JM1

Reviews

1 review available for alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid and Alcoholism

ArticleYear
Mechanisms of Action and Persistent Neuroplasticity by Drugs of Abuse.
    Pharmacological reviews, 2015, Volume: 67, Issue:4

    Topics: Alcoholism; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amphetamines; Animals; Behavio

2015

Other Studies

1 other study available for alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid and Alcoholism

ArticleYear
Genetic variability in the NMDA-dependent AMPA trafficking cascade is associated with alcohol dependence.
    Addiction biology, 2012, Volume: 17, Issue:4

    Topics: Alcoholism; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Calcium-Calmodulin-Dependent P

2012