alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid has been researched along with Age-Related Memory Disorders in 10 studies
alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid: An IBOTENIC ACID homolog and glutamate agonist. The compound is the defining agonist for the AMPA subtype of glutamate receptors (RECEPTORS, AMPA). It has been used as a radionuclide imaging agent but is more commonly used as an experimental tool in cell biological studies.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Learning and memory and drug addiction are modulated by the same neurotrophic factors, share certain intracellular signaling cascades, and depend on activation of the transcription factor CREB." | 1.31 | Common molecular and cellular substrates of addiction and memory. ( Nestler, EJ, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (10.00) | 18.2507 |
| 2000's | 3 (30.00) | 29.6817 |
| 2010's | 5 (50.00) | 24.3611 |
| 2020's | 1 (10.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ashourpour, F | 1 |
| Jafari, A | 1 |
| Babaei, P | 1 |
| Cui, J | 1 |
| Ng, LJ | 1 |
| Volman, V | 1 |
| Bretin, S | 1 |
| Krazem, A | 1 |
| Henkous, N | 1 |
| Froger-Colleaux, C | 1 |
| Mocaer, E | 1 |
| Louis, C | 1 |
| Perdaems, N | 1 |
| Marighetto, A | 1 |
| Beracochea, D | 1 |
| Nelson-Mora, J | 1 |
| Escobar, ML | 1 |
| Rodríguez-Durán, L | 1 |
| Massieu, L | 1 |
| Montiel, T | 1 |
| Rodríguez, VM | 1 |
| Hernández-Mercado, K | 1 |
| Gonsebatt, ME | 1 |
| Morice, E | 1 |
| Farley, S | 1 |
| Poirier, R | 1 |
| Dallerac, G | 1 |
| Chagneau, C | 1 |
| Pannetier, S | 1 |
| Hanauer, A | 1 |
| Davis, S | 1 |
| Vaillend, C | 1 |
| Laroche, S | 1 |
| Roberts, BM | 1 |
| Holden, DE | 1 |
| Shaffer, CL | 1 |
| Seymour, PA | 1 |
| Menniti, FS | 1 |
| Schmidt, CJ | 1 |
| Williams, GV | 1 |
| Castner, SA | 1 |
| Nestler, EJ | 1 |
| Saura, CA | 1 |
| Choi, SY | 2 |
| Beglopoulos, V | 1 |
| Malkani, S | 1 |
| Zhang, D | 2 |
| Shankaranarayana Rao, BS | 1 |
| Chattarji, S | 2 |
| Kelleher, RJ | 1 |
| Kandel, ER | 1 |
| Duff, K | 1 |
| Kirkwood, A | 2 |
| Shen, J | 1 |
| Hayashi, ML | 1 |
| Rao, BS | 1 |
| Jung, HY | 1 |
| Lee, HK | 1 |
| Tonegawa, S | 1 |
| Bradbury, EJ | 1 |
| Kershaw, TR | 1 |
| Marchbanks, RM | 1 |
| Sinden, JD | 1 |
10 other studies available for alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid and Age-Related Memory Disorders
| Article | Year |
|---|---|
Co-treatment of AMPA endocytosis inhibitor and GluN2B antagonist facilitate consolidation and retrieval of memory impaired by β amyloid peptide.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amyloid beta-Peptides; Animals; Endocytosi | 2022 |
Callosal injury-induced working memory impairment: a computational network modeling study.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Computer Simulation; Corpus Callo | 2017 |
Synergistic enhancing-memory effect of donepezil and S 47445, an AMPA positive allosteric modulator, in middle-aged and aged mice.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Alzheimer Disease; Animals; Benzoxazines; | 2018 |
Gestational exposure to inorganic arsenic (iAs3+) alters glutamate disposition in the mouse hippocampus and ionotropic glutamate receptor expression leading to memory impairment.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Arsenic; Dentate Gyrus; Female; G | 2018 |
Defective synaptic transmission and structure in the dentate gyrus and selective fear memory impairment in the Rsk2 mutant mouse model of Coffin-Lowry syndrome.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Coffin-Lowry Syndrome; Conditioni | 2013 |
Prevention of ketamine-induced working memory impairments by AMPA potentiators in a nonhuman primate model of cognitive dysfunction.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Analysis of Variance; Animals; Animals, Ne | 2010 |
Common molecular and cellular substrates of addiction and memory.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Brain; Corpus Striatum; Cyclic AMP Respons | 2002 |
Loss of presenilin function causes impairments of memory and synaptic plasticity followed by age-dependent neurodegeneration.
Topics: Activating Transcription Factor 1; Age Factors; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic | 2004 |
Altered cortical synaptic morphology and impaired memory consolidation in forebrain- specific dominant-negative PAK transgenic mice.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Analysis of Variance; Animals; Animals, Ne | 2004 |
Astrocyte transplants alleviate lesion induced memory deficits independently of cholinergic recovery.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Astrocytes; Brain Tissue Transpla | 1995 |