alovudine has been researched along with HIV in 13 studies
*HIV: Human immunodeficiency virus. A non-taxonomic and historical term referring to any of two species, specifically HIV-1 and/or HIV-2. Prior to 1986, this was called human T-lymphotropic virus type III/lymphadenopathy-associated virus (HTLV-III/LAV). From 1986-1990, it was an official species called HIV. Since 1991, HIV was no longer considered an official species name; the two species were designated HIV-1 and HIV-2. [MeSH]
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (30.77) | 18.7374 |
| 1990's | 8 (61.54) | 18.2507 |
| 2000's | 1 (7.69) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Balzarini, J; Bergstrom, DE; De Clercq, E; Mott, AW; Swartling, DJ | 1 |
| Baba, M; Balzarini, J; De Clercq, E; Herdewijn, P; Janssen, G; Pauwels, R; Van Aerschot, A | 1 |
| Baba, M; Balzarini, J; Broder, S; De Clercq, E; Herdewijn, P; Pauwels, R; Vanderhaeghe, H | 1 |
| Bravo, ML; Cotte, L; Dorléacq, N; Ghosn, J; Harmenberg, J; Katlama, C; Mårdh, G; Mayers, D; Piketty, C; Quinson, AM; Sabo, N; Valdez, H | 1 |
| Armstrong, D; Barditch-Crovo, PA; Baron, PA; Duncanson, F; Flexner, C; Ganes, D; Jacobson, MA; Petty, BG; Powderly, W; van der Horst, C | 1 |
| Faraj, A; Gosselin, G; Imbach, JL; Perigaud, C; Schinazi, RF; Sommadossi, JP; Xie, MY | 1 |
| Eriksson, S; Karlsson, A; Oberg, B; Olofsson, S | 1 |
| Armstrong, D; Chou, TC; Kong, XB; Lang, SA; Muchmore, E; Ostrander, M; Polsky, B; Vidal, PM; Watanabe, KA; Zhu, QY | 1 |
| Cox, S; Harmenberg, J; Koshida, R; Wahren, B | 1 |
| Balzarini, J; Blaton, N; De Clercq, E; De Ranter, C; Everaert, D; Gosselin, G; Herdewijn, P; Imbach, JL; Peeters, O; Van Aerschot, A | 1 |
| Camerman, A; Camerman, N; Mastropaolo, D | 1 |
| Balzarini, J; De Clercq, E; Johns, DG; Matthes, E; Meeus, P | 1 |
| Langen, P; Lehmann, C; Matthes, E; Rosenthal, HA; Scholz, D | 1 |
2 trial(s) available for alovudine and HIV
| Article | Year |
|---|---|
Antiviral activity of low-dose alovudine in antiretroviral-experienced patients: results from a 4-week randomized, double-blind, placebo-controlled dose-ranging trial.
Topics: Adult; Aged; Anti-HIV Agents; CD4 Lymphocyte Count; Dideoxynucleosides; Double-Blind Method; Female; HIV; HIV Infections; Humans; Male; Middle Aged; RNA, Viral; Viral Load | 2007 |
Relationship between plasma concentrations of 3'-deoxy-3'-fluorothymidine (alovudine) and antiretroviral activity in two concentration-controlled trials.
Topics: Adult; Aged; Antiviral Agents; CD4 Lymphocyte Count; Dideoxynucleosides; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Female; HIV; HIV Core Protein p24; HIV Infections; Humans; Male; Middle Aged; Prospective Studies | 1994 |
11 other study(ies) available for alovudine and HIV
| Article | Year |
|---|---|
3',3'-Difluoro-3'-deoxythymidine: comparison of anti-HIV activity to 3'-fluoro-3'-deoxythymidine.
Topics: Antiviral Agents; Dideoxynucleosides; HIV; Molecular Conformation; Structure-Activity Relationship | 1992 |
Synthesis and anti-HIV activity of different sugar-modified pyrimidine and purine nucleosides.
Topics: Animals; Antiviral Agents; Cell Line; Cytopathogenic Effect, Viral; HIV; Magnetic Resonance Spectroscopy; Purine Nucleosides; Pyrimidine Nucleosides; Structure-Activity Relationship; Virus Replication; Zidovudine | 1988 |
3'-substituted 2',3'-dideoxynucleoside analogues as potential anti-HIV (HTLV-III/LAV) agents.
Topics: Antiviral Agents; Cell Line; Chemical Phenomena; Chemistry; Cytopathogenic Effect, Viral; Deoxyribonucleosides; HIV; Humans; Structure-Activity Relationship; T-Lymphocytes; Virus Replication | 1987 |
Selective protection of toxicity of 2',3'-dideoxypyrimidine nucleoside analogs by beta-D-uridine in human granulocyte-macrophage progenitor cells.
Topics: Antiviral Agents; Bone Marrow Cells; Cells, Cultured; Dideoxynucleosides; Granulocytes; Hematopoietic Stem Cells; HIV; Humans; Macrophages; Molecular Structure; Uridine; Zidovudine | 1996 |
The HIV replication inhibitor 3'-fluoro-3'-deoxythymidine blocks sialylation of N-linked oligosaccharides.
Topics: Antibodies, Monoclonal; Antibodies, Viral; Antiviral Agents; Chromatography, High Pressure Liquid; Dideoxynucleosides; HIV; Oligosaccharides; Sialic Acids; Simplexvirus; Thymidine Kinase; Viral Envelope Proteins; Virus Replication | 1992 |
Comparisons of anti-human immunodeficiency virus activities, cellular transport, and plasma and intracellular pharmacokinetics of 3'-fluoro-3'-deoxythymidine and 3'-azido-3'-deoxythymidine.
Topics: Animals; Antiviral Agents; Cell Membrane Permeability; Cells, Cultured; Chromatography, High Pressure Liquid; Dideoxynucleosides; Female; HIV; Humans; Macaca fascicularis; Male; Tritium; Zidovudine | 1992 |
Synergistic combinations and peptides in the inhibition of human immunodeficiency virus.
Topics: Alpha-Globulins; Amino Acid Sequence; Antiviral Agents; Cell Line; Dideoxynucleosides; Drug Synergism; Foscarnet; HIV; Humans; Molecular Sequence Data; Oligopeptides; Phosphonoacetic Acid; Proteins; Reverse Transcriptase Inhibitors; Serine Proteinase Inhibitors; Virus Replication; Zidovudine | 1991 |
2'-Azido-2',3'-dideoxythymidine: synthesis and crystal structure of a 2'-substituted dideoxynucleoside.
Topics: Antiviral Agents; Crystallography; Dideoxynucleosides; HIV; Humans; In Vitro Techniques; Molecular Structure; Structure-Activity Relationship; Virus Replication; X-Ray Diffraction; Zidovudine | 1990 |
Structure of the anti-human immunodeficiency virus agent 3'-fluoro-3'-deoxythymidine and electronic charge calculations for 3'-deoxythymidines.
Topics: Antiviral Agents; Dideoxynucleosides; HIV; Hydrogen Bonding; Molecular Conformation; Molecular Structure; Thymidine | 1990 |
The antiretroviral and cytostatic activity, and metabolism of 3'-azido-2',3'-dideoxythymidine, 3'-fluoro-2',3'-dideoxythymidine and 2',3'-dideoxycytidine are highly cell type-dependent.
Topics: Antiviral Agents; Cell Division; Cell Line; Dideoxynucleosides; HIV; Humans; Virus Replication; Zalcitabine; Zidovudine | 1989 |
Phosphorylation, anti-HIV activity and cytotoxicity of 3'-fluorothymidine.
Topics: Animals; Antiviral Agents; Cell Division; Cell Line; Cell Survival; Cytidine Diphosphate; Cytopathogenic Effect, Viral; Dideoxynucleosides; HIV; Humans; Mice; Phosphorylation; Rats; Thymidine; Virus Replication; Zidovudine | 1988 |