alovudine has been researched along with Cancer of Lung in 60 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (1.67) | 18.2507 |
| 2000's | 20 (33.33) | 29.6817 |
| 2010's | 37 (61.67) | 24.3611 |
| 2020's | 2 (3.33) | 2.80 |
| Authors | Studies |
|---|---|
| Bando, Y; Ikushima, H; Kondo, K; Kuwahara, K; Miyoshi, H; Otani, T; Otsuka, H; Yamashita, M | 1 |
| Calderoni, L; Castellucci, P; Fanti, S; Telo, S; Vichi, S; Zagni, F | 1 |
| Kuang, A; Ma, H; Pang, F; Ren, P; Shen, G | 1 |
| Akoury, J; Douglas, KA; Gadgeel, S; Lawhorn-Crews, JM; Li, J; Mangner, TJ; McHugh, CI; Polin, L; Ratnam, M; Shields, AF; Thipparthi, MR | 1 |
| Gao, Y; Huang, Y; Li, C; Meng, X; Pang, L; Sun, X; Yu, J; Zhang, X | 1 |
| Aide, N; Beauregard, JM; Blum, R; Drummond, E; Giraudet, AL; Hicks, RJ; Hofman, MS; Roselt, P | 1 |
| Boellaard, R; Frings, V; Giovannetti, E; Herder, GJ; Hoekstra, OS; Honeywell, R; Peters, GJ; Smit, EF; Thunnissen, E; van der Veldt, AA | 1 |
| Boellaard, R; de Langen, AJ; Frings, V; Hoekstra, OS; Schuit, RC; Smit, EF; van der Veldt, AA; Yaqub, M | 1 |
| Aide, N; Berriolo-Riedinger, A; Blagosklonov, O; Brenot-Rossi, I; Bridji, B; Cachin, F; Caignon, JM; Chaumet-Riffaud, P; Collombier, L; Courbon, F; Devillers, A; Doyeux, K; Dubray, B; Fernandez, P; Gremillet, E; Houzard, C; Kolesnikov-Gauthier, H; Modzelewski, R; Olivier, P; Roux, J; Tessonnier, L; Thureau, S; Vera, P; Vervueren, L | 1 |
| Anton-Rodriguez, J; Asselin, MC; Blackhall, F; Earl, M; Faivre-Finn, C; Haslett, K; Jackson, A; Koh, PK; Ryder, D; Tamal, M; Taylor, B; Trigonis, I; Young, H | 1 |
| Jang, SJ; Kim, SY; Lee, EJ; Lee, HJ; Lee, JJ; Lee, SJ; Moon, DH; Ryu, JS; Yeo, JS | 1 |
| Aboagye, EO; Faber, C; Griffiths, J; Heinzmann, K; Hermann, S; Honess, DJ; Jacobs, AH; Kopka, K; Kuhlmann, MT; Müller-Tidow, C; Schäfers, M; Schelhaas, S; Schneider, R; Schober, O; Smith, DM; Viel, T; Wachsmuth, L; Wagner, S | 1 |
| Ball, DL; Binns, D; Callahan, J; Collins, M; Everitt, SJ; Herschtal, A; Hicks, RJ; Kron, T; MacManus, M; Plumridge, N; Schneider, M | 1 |
| Ball, DL; Chabrot, M; Everitt, SJ; Hicks, RJ; Leimgruber, A; MacManus, M; Möller, A; Solomon, B | 1 |
| Boellaard, R; Frings, V; Golla, SS; Hoekstra, OS; Hoyng, LL; Lammertsma, AA; Schuit, RC; Smit, EF; Windhorst, AD; Yaqub, M | 1 |
| Frechen, S; Fuhr, U; Kahraman, D; Kobe, C; Nogova, L; Scheffler, M; Suleiman, AA; Wolf, J; Zander, T | 1 |
| Fu, Z; Hu, M; Li, C; Liu, J; Lu, J; Meng, X; Shi, X; Sun, X; Xing, L; Yu, J | 1 |
| Bressel, M; Burbury, K; Callahan, J; Campbell, BA; Everitt, S; Hicks, RJ; Hofman, MS; MacManus, M; Simoens, N | 1 |
| Faber, C; Griffiths, JR; Heinzmann, K; Held, A; Hermann, S; Honess, DJ; Jacobs, AH; Schelhaas, S; Smith, DM; Wachsmuth, L | 1 |
| Briston, DA; Douglas, KA; Gadgeel, S; Heilbrun, LK; Lawhorn-Crews, JM; Mangner, TJ; Muzik, O; Shields, AF; Zalzala, S | 1 |
| Boellaard, R; de Bree, R; de Langen, AJ; Hoekstra, OS; Klabbers, B; Lammertsma, AA; Lubberink, M; Slotman, BJ; Smit, EF; Spreeuwenberg, MD | 1 |
| Backes, H; Borgman, CL; Jacobs, AH; Koker, M; Li, H; Neumaier, B; Shapiro, GI; Shimamura, T; Sos, ML; Tawadros, S; Thomas, RK; Ullrich, RT; Waerzeggers, Y; Winkeler, A; Wolf, J; Zander, T | 1 |
| Ball, D; Binns, D; Everitt, S; Hicks, RJ; Kron, T; Mac Manus, M; Schneider-Kolsky, M; Walter, T | 1 |
| Fu, Z; Han, A; Mu, D; Sun, X; Yang, W; Yu, J; Zhang, Y | 1 |
| Baba, M; Fukumura, T; Inubushi, M; Koizumi, M; Nakajima, M; Saga, T; Sugane, T; Yamamoto, N; Yoshikawa, K | 1 |
| Bohn, P; Dubray, B; Edet-Sanson, A; Gardin, I; Hapdey, S; Ménard, JF; Modzelewski, R; Salles, A; Thiberville, L; Vera, P | 1 |
| Boellaard, R; de Langen, AJ; Frings, V; Hoekstra, OS; Smit, EF; van Tinteren, H; van Velden, FH | 1 |
| Binns, DS; Callahan, J; Conti, P; Fine, BM; Hicks, RJ; Macfarlane, D; Mileshkin, L; Pirzkall, A; Scott, AM; Yu, W | 1 |
| Baba, M; Fukumura, T; Inubushi, M; Koizumi, M; Miyamoto, T; Nakajima, M; Saga, T; Tanimoto, K; Yamamoto, N; Yoshikawa, K | 1 |
| Boellaard, R; Buettner, R; Dietlein, M; Draube, A; Engel-Riedel, W; Hallek, M; Hellmich, M; Heukamp, L; Jacobs, AH; Ko, YD; Kobe, C; Lammertsma, AA; Neumaier, B; Nogova, L; Papachristou, I; Querings, S; Scheffler, M; Schlesinger, A; Schulte, K; Smit, E; Stoelben, E; Thomas, RK; Toepelt, K; Ullrich, RT; Wolf, J; Zander, T | 1 |
| Dosaka-Akita, H; Hatano, T; Kinoshita, I; Kuge, Y; Nishijima, K; Shimizu, Y; Takeuchi, S; Tamaki, N; Zhao, S; Zhao, Y | 1 |
| Lee, HJ; Lee, SJ; Moon, DH | 1 |
| Boellaard, R; Cheebsumon, P; de Langen, AJ; Frings, V; Hoekstra, OS; Lammertsma, AA; van Velden, FH; Yaqub, M | 1 |
| Boellaard, R; Dietlein, M; Holstein, A; Kahraman, D; Kobe, C; Lammertsma, AA; Neumaier, B; Nogova, L; Scheffler, M; Ullrich, RT; Wolf, J; Zander, T | 2 |
| Del Vecchio, S; Iommelli, F; Salvatore, M; Speranza, A; Zannetti, A | 1 |
| Fu, Z; Mu, D; Sun, X; Yang, W; Yu, J; Zhang, Y | 1 |
| Civelek, AC; Huang, T; Jiang, H; Li, J; Li, XF; Ng, CK; Postel, GC; Shen, B | 1 |
| Dietlein, M; Kahraman, D; Kobe, C; Neumaier, B; Nogova, L; Scheffler, M; Thomas, R; Wolf, J; Zander, T | 1 |
| Asher, C; Chu, SK; Garwin, GG; Johnson, BW; Krohn, KA; Li, T; Miyaoka, RS; Plotnik, DA; Schwartz, JL | 1 |
| Boellaard, R; Dietlein, M; Holstein, A; Kahraman, D; Kobe, C; Lammertsma, AA; Neumaier, B; Nogova, L; Scheffler, M; Wolf, J; Zander, T | 1 |
| Chang, E; Cheng, Z; Jiang, H; Liu, H; Xu, Y | 1 |
| Boellaard, R; Büttner, R; Dietlein, M; Engel-Riedel, W; Heukamp, L; Kahraman, D; Kobe, C; Lammertsma, AA; Neumaier, B; Nogova, L; Papachristou, I; Querings, S; Scheffler, M; Stoelben, E; Wolf, J; Zander, T | 1 |
| Grierson, JR; Kolb, PD; Rasey, JS; Schwartz, JL; Wiens, LW | 1 |
| Grierson, J; Muzi, M; Peterson, LM; Pugsley, JM; Rabinowitz, P; Schmidt, RA; Vallières, E; Vesselle, H; Wood, DE | 1 |
| Grierson, J; Krohn, KA; Mankoff, DA; Muzi, M; Peterson, LM; Vesselle, H | 1 |
| Grierson, JR; Jordan, R; Krohn, KA; Schwartz, JL; Tamura, Y | 1 |
| Grierson, JR; Jordan, R; Krohn, KA; Muzi, M; Schwartz, JL | 1 |
| Cobben, DC; Elsinga, PH; Groen, HM; Hoekstra, HJ; Jager, PL; Maas, B; Suurmeijer, AJ; Vaalburg, W | 1 |
| Buck, AK; Glatting, G; Halter, G; Hetzel, M; Kratochwil, C; Mattfeldt, T; Möller, P; Mottaghy, FM; Neumaier, B; Reske, SN; Schirrmeister, H; Wahl, A | 1 |
| Grierson, JR; Krohn, KA; Mankoff, DA; Muzi, M; Peterson, L; Schmidt, RA; Vesselle, H; Wells, JM | 1 |
| Chen, DL; Dehdashti, F | 1 |
| Cameron, RB; Czernin, J; Fishbein, MC; Phelps, ME; Schiepers, C; Weber, WA; Yap, CS | 1 |
| Liang, ZY; Liu, X; Zhang, JM; Zheng, X; Zhou, NK | 1 |
| Bandoh, S; Chang, SS; Haba, R; Ishikawa, S; Kanaji, N; Kushida, Y; Nakano, J; Nishiyama, Y; Ohkawa, M; Yamamoto, Y | 1 |
| Asakura, M; Bandoh, S; Ishikawa, S; Kanaji, N; Kimura, N; Nishiyama, Y; Ohkawa, M; Okuda, M; Yamamoto, Y | 1 |
| Alauddin, MM; Bornmann, W; Gelovani, JG; Mawlawi, O; Mukhopadhyay, U; Nishii, R; Pal, A; Volgin, AY | 1 |
| Chen, P; Feng, H; Ma, L; Tan, Y; Tian, J; Wu, W; Xin, J; Yang, X; Yu, L; Zhao, Z | 1 |
| Dohmen, BM; Grierson, JR; Lawhorn-Crews, JM; Machulla, HJ; Mangner, TJ; Muzik, O; Obradovich, JE; Shields, AF; Stayanoff, JC | 1 |
| Buck, AK; Glatting, G; Halter, G; Hetzel, M; Liewald, F; Mattfeldt, T; Neumaier, B; Reske, SN; Schirrmeister, H; Von Der Heide, M | 1 |
3 review(s) available for alovudine and Cancer of Lung
| Article | Year |
|---|---|
Alternative and New Radiopharmaceutical Agents for Lung Cancer.
Topics: Acetates; Carbon Radioisotopes; Dideoxynucleosides; Fluorodeoxyglucose F18; Gallium Isotopes; Gallium Radioisotopes; Humans; Lung Neoplasms; Methionine; Misonidazole; Neoplasm Staging; Neuroendocrine Tumors; Peptides; Peptides, Cyclic; Positron Emission Tomography Computed Tomography; Quinolines; Radiopharmaceuticals; Sensitivity and Specificity | 2020 |
Correlations of 18F-FDG and 18F-FLT uptake on PET with Ki-67 expression in patients with lung cancer: a meta-analysis.
Topics: Dideoxynucleosides; Fluorodeoxyglucose F18; Humans; Ki-67 Antigen; Lung Neoplasms; Positron-Emission Tomography; Sensitivity and Specificity | 2018 |
Advances in positron emission tomographic imaging of lung cancer.
Topics: Carbon Radioisotopes; Carcinoma, Non-Small-Cell Lung; Dideoxynucleosides; Fluorine Radioisotopes; Fluorodeoxyglucose F18; Humans; Hypoxia; Lung Neoplasms; Positron-Emission Tomography; Radiopharmaceuticals | 2005 |
18 trial(s) available for alovudine and Cancer of Lung
| Article | Year |
|---|---|
Evaluation of a new visual uptake scoring scale for 18F-fluorothymidine positron emission tomography in the diagnosis of pulmonary lesions.
Topics: Adult; Aged; Aged, 80 and over; Biological Transport; Dideoxynucleosides; Female; Humans; Lung Neoplasms; Male; Middle Aged; Observer Variation; Positron-Emission Tomography; ROC Curve | 2013 |
Methodological considerations in quantification of 3'-deoxy-3'-[18F]fluorothymidine uptake measured with positron emission tomography in patients with non-small cell lung cancer.
Topics: Adult; Aged; Calibration; Carcinoma, Non-Small-Cell Lung; Demography; Dideoxynucleosides; Female; Humans; Lung Neoplasms; Male; Middle Aged; Nonlinear Dynamics; Positron-Emission Tomography; Regression Analysis | 2014 |
Interobserver agreement of qualitative analysis and tumor delineation of 18F-fluoromisonidazole and 3'-deoxy-3'-18F-fluorothymidine PET images in lung cancer.
Topics: Adult; Aged; Algorithms; Carcinoma, Non-Small-Cell Lung; Dideoxynucleosides; Female; Fluorodeoxyglucose F18; Humans; Image Enhancement; Image Interpretation, Computer-Assisted; Lung Neoplasms; Male; Middle Aged; Misonidazole; Observer Variation; Positron-Emission Tomography; Radiopharmaceuticals; Reproducibility of Results; Sensitivity and Specificity; Tumor Burden | 2013 |
Effect of Platinum-Based Chemoradiotherapy on Cellular Proliferation in Bone Marrow and Spleen, Estimated by (18)F-FLT PET/CT in Patients with Locally Advanced Non-Small Cell Lung Cancer.
Topics: Adult; Aged; Aged, 80 and over; Bone Marrow Cells; Carcinoma, Non-Small-Cell Lung; Cell Count; Cell Proliferation; Chemoradiotherapy; Dideoxynucleosides; Female; Fluorodeoxyglucose F18; Glucose; Humans; Lung Neoplasms; Male; Middle Aged; Neutrophils; Organ Specificity; Platinum; Positron-Emission Tomography; Spleen; Tomography, X-Ray Computed | 2014 |
Modeling tumor dynamics and overall survival in advanced non-small-cell lung cancer treated with erlotinib.
Topics: Adult; Aged; Carcinoma, Non-Small-Cell Lung; Cohort Studies; Dideoxynucleosides; Erlotinib Hydrochloride; Female; Fluorodeoxyglucose F18; Humans; Lung Neoplasms; Male; Middle Aged; Positron-Emission Tomography; Prognosis; Protein Kinase Inhibitors; Quinazolines; Radiopharmaceuticals; Survival Analysis | 2015 |
Imaging of proliferation with 18F-FLT PET/CT versus 18F-FDG PET/CT in non-small-cell lung cancer.
Topics: Adult; Aged; Aged, 80 and over; Biological Transport; Carcinoma, Non-Small-Cell Lung; Cell Proliferation; Cyclin D1; Dideoxynucleosides; Female; Fluorodeoxyglucose F18; Humans; Immunohistochemistry; Lung Neoplasms; Male; Middle Aged; Neoplasm Staging; Positron-Emission Tomography; Tomography, X-Ray Computed | 2010 |
Uptake decrease of proliferative PET tracer 18FLT in bone marrow after carbon ion therapy in lung cancer.
Topics: Aged; Bone Marrow; Carbon; Cell Proliferation; Demography; Dideoxynucleosides; Female; Humans; Ions; Lumbar Vertebrae; Lung Neoplasms; Male; Positron-Emission Tomography; Radiopharmaceuticals; Tomography, X-Ray Computed | 2011 |
Compliance with PET acquisition protocols for therapeutic monitoring of erlotinib therapy in an international trial for patients with non-small cell lung cancer.
Topics: Biological Transport; Blood Glucose; Carcinoma, Non-Small-Cell Lung; Dideoxynucleosides; Erlotinib Hydrochloride; Feasibility Studies; Fluorodeoxyglucose F18; Guideline Adherence; Humans; Internationality; Lung Neoplasms; Positron-Emission Tomography; Quality Control; Quinazolines; Treatment Outcome | 2011 |
Early prediction of nonprogression in advanced non-small-cell lung cancer treated with erlotinib by using [(18)F]fluorodeoxyglucose and [(18)F]fluorothymidine positron emission tomography.
Topics: Adult; Aged; Carcinoma, Non-Small-Cell Lung; Dideoxynucleosides; Disease-Free Survival; Erlotinib Hydrochloride; Female; Fluorodeoxyglucose F18; Genes, erbB-1; Humans; Lung Neoplasms; Male; Middle Aged; Mutation; Positron-Emission Tomography; Prognosis; Quinazolines | 2011 |
Quantitative analysis of response to treatment with erlotinib in advanced non-small cell lung cancer using 18F-FDG and 3'-deoxy-3'-18F-fluorothymidine PET.
Topics: Carcinoma, Non-Small-Cell Lung; Dideoxynucleosides; Disease-Free Survival; Erlotinib Hydrochloride; Female; Fluorodeoxyglucose F18; Humans; Lung Neoplasms; Male; Neoplasm Staging; Positron-Emission Tomography; Quinazolines; Time Factors; Treatment Outcome | 2011 |
Imaging proliferation of ¹⁸F-FLT PET/CT correlated with the expression of microvessel density of tumour tissue in non-small-cell lung cancer.
Topics: Adult; Aged; Aged, 80 and over; Antigens, CD; Biological Transport; Carcinoma, Non-Small-Cell Lung; Cell Proliferation; Dideoxynucleosides; Female; Gene Expression Regulation, Neoplastic; Humans; Ki-67 Antigen; Lung Neoplasms; Male; Microvessels; Middle Aged; Multimodal Imaging; Neovascularization, Pathologic; Positron-Emission Tomography; Prognosis; Tomography, X-Ray Computed | 2012 |
Tumor lesion glycolysis and tumor lesion proliferation for response prediction and prognostic differentiation in patients with advanced non-small cell lung cancer treated with erlotinib.
Topics: Adult; Aged; Carcinoma, Non-Small-Cell Lung; Cell Proliferation; Dideoxynucleosides; Disease-Free Survival; Erlotinib Hydrochloride; Female; Fluorodeoxyglucose F18; Glycolysis; Humans; Kaplan-Meier Estimate; Lung Neoplasms; Male; Middle Aged; Neoplasm Staging; Positron-Emission Tomography; Prognosis; Quinazolines; Treatment Outcome | 2012 |
Prognostic impact of [18F]fluorothymidine and [18F]fluoro-D-glucose baseline uptakes in patients with lung cancer treated first-line with erlotinib.
Topics: Adult; Aged; Carcinoma, Non-Small-Cell Lung; Dideoxynucleosides; Erlotinib Hydrochloride; Female; Fluorodeoxyglucose F18; Genes, erbB-1; Humans; Kaplan-Meier Estimate; Lung; Lung Neoplasms; Male; Middle Aged; Mutation; Positron-Emission Tomography; Prognosis; Protein Kinase Inhibitors; Quinazolines | 2013 |
18F-Fluorothymidine radiation dosimetry in human PET imaging studies.
Topics: Aged; Aged, 80 and over; Dideoxynucleosides; Female; Humans; Lung Neoplasms; Male; Metabolic Clearance Rate; Middle Aged; Organ Specificity; Radiation Dosage; Radioisotope Dilution Technique; Radiometry; Radiopharmaceuticals; Risk Assessment; Tissue Distribution; Tomography, Emission-Computed; Whole-Body Counting | 2003 |
Is 18F-3'-fluoro-3'-deoxy-L-thymidine useful for the staging and restaging of non-small cell lung cancer?
Topics: Adult; Aged; Carcinoma, Non-Small-Cell Lung; Dideoxynucleosides; Female; Humans; Lung Neoplasms; Male; Middle Aged; Neoplasm Staging; Radionuclide Imaging; Radiopharmaceuticals; Reproducibility of Results; Sensitivity and Specificity | 2004 |
Clinical relevance of imaging proliferative activity in lung nodules.
Topics: Adult; Aged; Aged, 80 and over; Dideoxynucleosides; Female; Fluorodeoxyglucose F18; Humans; Lung Neoplasms; Male; Middle Aged; Neoplasm Invasiveness; Neoplasm Staging; Radionuclide Imaging; Radiopharmaceuticals; Reproducibility of Results; Sensitivity and Specificity; Severity of Illness Index; Solitary Pulmonary Nodule | 2005 |
Kinetic analysis of 3'-deoxy-3'-fluorothymidine PET studies: validation studies in patients with lung cancer.
Topics: Algorithms; Carcinoma, Non-Small-Cell Lung; Computer Simulation; Dideoxynucleosides; Humans; Image Interpretation, Computer-Assisted; Kinetics; Lung Neoplasms; Metabolic Clearance Rate; Models, Biological; Neoplasm Invasiveness; Neoplasm Staging; Organ Specificity; Radioisotope Dilution Technique; Radionuclide Imaging; Radiopharmaceuticals; Reproducibility of Results; Sensitivity and Specificity; Tissue Distribution | 2005 |
3-deoxy-3-[(18)F]fluorothymidine-positron emission tomography for noninvasive assessment of proliferation in pulmonary nodules.
Topics: Adult; Aged; Aged, 80 and over; Cell Division; Dideoxynucleosides; Female; Fluorine Radioisotopes; Humans; Immunohistochemistry; Ki-67 Antigen; Lung Neoplasms; Male; Middle Aged; Prospective Studies; Radiopharmaceuticals; Tomography, Emission-Computed | 2002 |
39 other study(ies) available for alovudine and Cancer of Lung
| Article | Year |
|---|---|
Early Prediction of Radiotherapeutic Efficacy in a Mouse Model of Non-Small Cell Lung Carcinoma Using
Topics: Animals; Carcinoma, Non-Small-Cell Lung; Fluorodeoxyglucose F18; Humans; Lung Neoplasms; Mice; Positron Emission Tomography Computed Tomography; Positron-Emission Tomography; Radiopharmaceuticals | 2023 |
Using Radiolabeled 3'-Deoxy-3'-
Topics: Animals; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Transformation, Neoplastic; Dexamethasone; Dideoxynucleosides; Humans; Isotope Labeling; Lung Neoplasms; Mice; Neoplasm Metastasis; Pilot Projects; Positron-Emission Tomography; Treatment Outcome | 2018 |
Spatial Concordance of Tumor Proliferation and Accelerated Repopulation from Pathologic Images to 3'-[
Topics: A549 Cells; Animals; Cell Proliferation; Dideoxynucleosides; Feasibility Studies; Female; Humans; Lung Neoplasms; Mice, Inbred BALB C; Mice, Nude; Positron-Emission Tomography; Radiotherapy Dosage; Tomography, X-Ray Computed | 2019 |
Pemetrexed induced thymidylate synthase inhibition in non-small cell lung cancer patients: a pilot study with 3'-deoxy-3'-[¹⁸F]fluorothymidine positron emission tomography.
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Carcinoma, Non-Small-Cell Lung; Deoxyuridine; Dideoxynucleosides; Female; Glutamates; Guanine; Humans; Lung Neoplasms; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Neoplasm Metastasis; Outcome Assessment, Health Care; Pemetrexed; Polymorphism, Genetic; Positron-Emission Tomography; Prognosis; Thymidylate Synthase; Time Factors; Tissue Distribution | 2013 |
Early reduction in tumour [18F]fluorothymidine (FLT) uptake in patients with non-small cell lung cancer (NSCLC) treated with radiotherapy alone.
Topics: Aged; Aged, 80 and over; Carcinoma, Non-Small-Cell Lung; Dideoxynucleosides; Female; Humans; Lung Neoplasms; Male; Middle Aged; Positron-Emission Tomography; Radiopharmaceuticals; Reproducibility of Results | 2014 |
Thymidine phosphorylase influences [(18)F]fluorothymidine uptake in cancer cells and patients with non-small cell lung cancer.
Topics: Adult; Aged; Biological Transport; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Dideoxynucleosides; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Gene Expression Regulation, Neoplastic; Humans; Intracellular Space; Lung Neoplasms; Male; Middle Aged; Pyrrolidines; Thymidine; Thymidine Phosphorylase; Thymine; Time Factors | 2014 |
Variability of Proliferation and Diffusion in Different Lung Cancer Models as Measured by 3'-Deoxy-3'-¹⁸F-Fluorothymidine PET and Diffusion-Weighted MR Imaging.
Topics: Animals; Biological Transport; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Proliferation; Cell Transformation, Neoplastic; Dideoxynucleosides; Diffusion; Diffusion Magnetic Resonance Imaging; Female; Fluorodeoxyglucose F18; Humans; Kinetics; Lung Neoplasms; Mice; Positron-Emission Tomography | 2014 |
Differential (18)F-FDG and (18)F-FLT Uptake on Serial PET/CT Imaging Before and During Definitive Chemoradiation for Non-Small Cell Lung Cancer.
Topics: Aged; Aged, 80 and over; Biological Transport; Carcinoma, Non-Small-Cell Lung; Cell Proliferation; Chemoradiotherapy; Dideoxynucleosides; Disease Progression; Female; Fluorodeoxyglucose F18; Follow-Up Studies; Humans; Lung Neoplasms; Male; Middle Aged; Multimodal Imaging; Neoplasm Staging; Positron-Emission Tomography; Survival Analysis; Tomography, X-Ray Computed | 2014 |
Assessment of simplified methods to measure 18F-FLT uptake changes in EGFR-mutated non-small cell lung cancer patients undergoing EGFR tyrosine kinase inhibitor treatment.
Topics: Aged; Carcinoma, Non-Small-Cell Lung; Dideoxynucleosides; ErbB Receptors; Female; Fluorine Radioisotopes; Humans; Lung Neoplasms; Male; Middle Aged; Mutation; Prospective Studies; Protein Kinase Inhibitors; Radionuclide Imaging; Radiopharmaceuticals | 2014 |
Exploring spatial overlap of high-uptake regions derived from dual tracer positron emission tomography-computer tomography imaging using 18F-fluorodeoxyglucose and 18F-fluorodeoxythymidine in nonsmall cell lung cancer patients: a prospective pilot study.
Topics: Adult; Aged; Carcinoma, Non-Small-Cell Lung; Dideoxynucleosides; Female; Fluorodeoxyglucose F18; Humans; Lung Neoplasms; Male; Middle Aged; Multimodal Imaging; Neoplasm Staging; Pilot Projects; Positron-Emission Tomography; Prospective Studies; Radiation Dosage; Radiographic Image Interpretation, Computer-Assisted; Radiopharmaceuticals; Tomography, X-Ray Computed | 2015 |
Distribution Atlas of Proliferating Bone Marrow in Non-Small Cell Lung Cancer Patients Measured by FLT-PET/CT Imaging, With Potential Applicability in Radiation Therapy Planning.
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Bone and Bones; Bone Marrow; Carcinoma, Non-Small-Cell Lung; Dideoxynucleosides; Drug Dosage Calculations; Female; Fluorine Radioisotopes; Humans; Lung Neoplasms; Male; Medical Illustration; Middle Aged; Multimodal Imaging; Organ Specificity; Positron-Emission Tomography; Radiotherapy Planning, Computer-Assisted; Retrospective Studies; Sex Factors; Smoking; Tomography, X-Ray Computed | 2015 |
Gemcitabine Mechanism of Action Confounds Early Assessment of Treatment Response by 3'-Deoxy-3'-[18F]Fluorothymidine in Preclinical Models of Lung Cancer.
Topics: Animals; Antineoplastic Agents; Blotting, Western; Cell Line, Tumor; Deoxycytidine; Dideoxynucleosides; Diffusion Magnetic Resonance Imaging; Disease Models, Animal; Female; Flow Cytometry; Gemcitabine; Humans; Image Processing, Computer-Assisted; Immunohistochemistry; Lung Neoplasms; Mice; Mice, Nude; Positron-Emission Tomography; Radiopharmaceuticals; Xenograft Model Antitumor Assays | 2016 |
Analysis and reproducibility of 3'-Deoxy-3'-[18F]fluorothymidine positron emission tomography imaging in patients with non-small cell lung cancer.
Topics: Aged; Carcinoma, Non-Small-Cell Lung; Dideoxynucleosides; Female; Humans; Image Processing, Computer-Assisted; Lung Neoplasms; Male; Middle Aged; Positron-Emission Tomography; Radiopharmaceuticals; Reproducibility of Results | 2008 |
Reproducibility of quantitative 18F-3'-deoxy-3'-fluorothymidine measurements using positron emission tomography.
Topics: Carcinoma, Non-Small-Cell Lung; Dideoxynucleosides; Fluorine Radioisotopes; Head and Neck Neoplasms; Humans; Lung Neoplasms; Lymphatic Metastasis; Positron-Emission Tomography; Prospective Studies; Radiopharmaceuticals; Reproducibility of Results | 2009 |
Early detection of erlotinib treatment response in NSCLC by 3'-deoxy-3'-[F]-fluoro-L-thymidine ([F]FLT) positron emission tomography (PET).
Topics: Animals; Carcinoma, Non-Small-Cell Lung; Cell Cycle; Cell Line, Tumor; Dideoxynucleosides; Down-Regulation; Early Detection of Cancer; ErbB Receptors; Erlotinib Hydrochloride; Humans; Immunohistochemistry; In Situ Nick-End Labeling; Ki-67 Antigen; Lung Neoplasms; Mice; Positron-Emission Tomography; Quinazolines; Signal Transduction; Treatment Outcome; Xenograft Model Antitumor Assays | 2008 |
Imaging cellular proliferation during chemo-radiotherapy: a pilot study of serial 18F-FLT positron emission tomography/computed tomography imaging for non-small-cell lung cancer.
Topics: Aged; Carcinoma, Non-Small-Cell Lung; Cell Proliferation; Combined Modality Therapy; Dideoxynucleosides; Female; Fluorine Radioisotopes; Fluorodeoxyglucose F18; Humans; Lung Neoplasms; Male; Middle Aged; Pilot Projects; Positron-Emission Tomography; Radiopharmaceuticals; Tomography, X-Ray Computed | 2009 |
Simultaneous positron emission tomography (PET) assessment of metabolism with ¹⁸F-fluoro-2-deoxy-d-glucose (FDG), proliferation with ¹⁸F-fluoro-thymidine (FLT), and hypoxia with ¹⁸fluoro-misonidazole (F-miso) before and during radiotherapy in patients wit
Topics: Aged; Carcinoma, Non-Small-Cell Lung; Cell Proliferation; Dideoxynucleosides; Female; Fluorodeoxyglucose F18; Humans; Lung Neoplasms; Male; Middle Aged; Misonidazole; Pilot Projects; Positron-Emission Tomography; Radiopharmaceuticals; Tomography, X-Ray Computed | 2011 |
Repeatability of metabolically active volume measurements with 18F-FDG and 18F-FLT PET in non-small cell lung cancer.
Topics: Aged; Carcinoma, Non-Small-Cell Lung; Dideoxynucleosides; Female; Fluorodeoxyglucose F18; Humans; Image Interpretation, Computer-Assisted; Lung Neoplasms; Male; Middle Aged; Phantoms, Imaging; Prospective Studies; Radionuclide Imaging; Radiopharmaceuticals; Reproducibility of Results | 2010 |
PET/CT with 3'-deoxy-3'-[18F]fluorothymidine for lung cancer patients receiving carbon-ion radiotherapy.
Topics: Aged; Aged, 80 and over; Carbon; Dideoxynucleosides; Female; Fluorodeoxyglucose F18; Humans; Kaplan-Meier Estimate; Lung Neoplasms; Male; Middle Aged; Positron-Emission Tomography; Radiopharmaceuticals | 2011 |
18F-fluorothymidine PET/CT as an early predictor of tumor response to treatment with cetuximab in human lung cancer xenografts.
Topics: Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cetuximab; Dideoxynucleosides; Humans; Ki-67 Antigen; Lung Neoplasms; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Transplantation; Positron-Emission Tomography; Transplantation, Heterologous; Tumor Burden | 2011 |
Quantitative analysis of thymidine kinase 1 and 5'(3')-deoxyribonucleotidase mRNA expression: the role of fluorothymidine uptake.
Topics: 5'-Nucleotidase; Cell Line, Tumor; Colonic Neoplasms; Dideoxynucleosides; HCT116 Cells; HT29 Cells; Humans; Lung Neoplasms; RNA, Messenger; Thymidine Kinase; Tritium | 2011 |
Effects of image characteristics on performance of tumor delineation methods: a test-retest assessment.
Topics: Carcinoma, Non-Small-Cell Lung; Dideoxynucleosides; Female; Fluorine Radioisotopes; Fluorodeoxyglucose F18; Humans; Image Interpretation, Computer-Assisted; Lung Neoplasms; Male; Middle Aged; Positron-Emission Tomography; Radiopharmaceuticals; Retrospective Studies | 2011 |
3'-deoxy-3'-18F-fluorothymidine PET/CT to guide therapy with epidermal growth factor receptor antagonists and Bcl-xL inhibitors in non-small cell lung cancer.
Topics: Aniline Compounds; Animals; Antineoplastic Agents; Apoptosis; bcl-X Protein; Blotting, Western; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Proliferation; Dideoxynucleosides; Drug Resistance, Neoplasm; ErbB Receptors; Erlotinib Hydrochloride; Female; Image Processing, Computer-Assisted; Lung Neoplasms; Mice; Mice, Inbred BALB C; Multimodal Imaging; Positron-Emission Tomography; Protein Kinase Inhibitors; Quinazolines; Radiopharmaceuticals; Sulfonamides; Tomography, X-Ray Computed | 2012 |
Predictive value of early and late residual 18F-fluorodeoxyglucose and 18F-fluorothymidine uptake using different SUV measurements in patients with non-small-cell lung cancer treated with erlotinib.
Topics: Adult; Aged; Carcinoma, Non-Small-Cell Lung; Dideoxynucleosides; Discriminant Analysis; Disease-Free Survival; Erlotinib Hydrochloride; Female; Fluorodeoxyglucose F18; Humans; Kaplan-Meier Estimate; Lung Neoplasms; Male; Middle Aged; Positron-Emission Tomography; Predictive Value of Tests; Quinazolines; Radiopharmaceuticals; Retrospective Studies; ROC Curve | 2012 |
Tumor microenvironment-dependent 18F-FDG, 18F-fluorothymidine, and 18F-misonidazole uptake: a pilot study in mouse models of human non-small cell lung cancer.
Topics: Animals; Biological Transport; Bromodeoxyuridine; Carcinoma, Non-Small-Cell Lung; Cell Hypoxia; Cell Line, Tumor; Cell Proliferation; Dideoxynucleosides; Disease Models, Animal; Female; Fluorine Radioisotopes; Fluorodeoxyglucose F18; Humans; Lung Neoplasms; Mice; Misonidazole; Necrosis; Nitroimidazoles; Pilot Projects; Positron-Emission Tomography; Radioactive Tracers; Tumor Microenvironment | 2012 |
Monitoring reversible and irreversible EGFR inhibition with erlotinib and afatinib in a patient with EGFR-mutated non-small cell lung cancer (NSCLC) using sequential [18F]fluorothymidine (FLT-)PET.
Topics: Adenocarcinoma; Afatinib; Aged; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Dideoxynucleosides; DNA Mutational Analysis; Drug Resistance, Neoplasm; ErbB Receptors; Erlotinib Hydrochloride; Fatal Outcome; Female; Humans; Lung Neoplasms; Quinazolines; Radionuclide Imaging; Radiopharmaceuticals; Sequence Deletion | 2012 |
Levels of human equilibrative nucleoside transporter-1 are higher in proliferating regions of A549 tumor cells grown as tumor xenografts in vivo.
Topics: Adenocarcinoma; Adenocarcinoma of Lung; Animals; Biological Transport; Cell Line, Tumor; Cell Proliferation; Cell Transformation, Neoplastic; Dideoxynucleosides; Equilibrative Nucleoside Transporter 1; Humans; Lung Neoplasms; Male; Mice; Positron-Emission Tomography; Protein Transport | 2012 |
Cerenkov Luminescence Imaging (CLI) for cancer therapy monitoring.
Topics: Angiogenesis Inhibitors; Animals; Antibodies, Monoclonal, Humanized; Bevacizumab; Dideoxynucleosides; Female; Humans; Luminescent Measurements; Lung Neoplasms; Mice; Mice, Nude; Positron-Emission Tomography; Radiopharmaceuticals; Xenograft Model Antitumor Assays | 2012 |
Validation of FLT uptake as a measure of thymidine kinase-1 activity in A549 carcinoma cells.
Topics: Adenocarcinoma; Cell Cycle; Cell Division; Culture Media; Dideoxynucleosides; Fluorine Radioisotopes; Humans; Lung Neoplasms; Thymidine Kinase; Tumor Cells, Cultured | 2002 |
In vivo validation of 3'deoxy-3'-[(18)F]fluorothymidine ([(18)F]FLT) as a proliferation imaging tracer in humans: correlation of [(18)F]FLT uptake by positron emission tomography with Ki-67 immunohistochemistry and flow cytometry in human lung tumors.
Topics: Carcinoma, Non-Small-Cell Lung; Cell Division; Dideoxynucleosides; Flow Cytometry; Fluorescent Dyes; Fluorine Radioisotopes; Humans; Immunohistochemistry; Ki-67 Antigen; Lung Neoplasms; Tomography, Emission-Computed | 2002 |
Effect of p53 activation on cell growth, thymidine kinase-1 activity, and 3'-deoxy-3'fluorothymidine uptake.
Topics: Adenocarcinoma; Cell Division; Cell Line, Tumor; Dideoxynucleosides; Dose-Response Relationship, Radiation; Enzyme Activation; Gamma Rays; Humans; Lung Neoplasms; Thymidine Kinase; Tumor Suppressor Protein p53 | 2004 |
Metabolism of 3'-deoxy-3'-[F-18]fluorothymidine in proliferating A549 cells: validations for positron emission tomography.
Topics: Adenocarcinoma; Cell Line, Tumor; Cell Proliferation; Dideoxynucleosides; Humans; Kinetics; Lung Neoplasms; Metabolic Clearance Rate; Neoplasm Staging; Positron-Emission Tomography; Radiopharmaceuticals | 2004 |
Evaluation of thoracic tumors with 18F-fluorothymidine and 18F-fluorodeoxyglucose-positron emission tomography.
Topics: Aged; Carcinoma, Non-Small-Cell Lung; Dideoxynucleosides; Female; Fluorodeoxyglucose F18; Humans; Immunohistochemistry; Ki-67 Antigen; Lung Neoplasms; Lymphatic Metastasis; Male; Neoplasm Staging; Positron-Emission Tomography; Radiopharmaceuticals; Sensitivity and Specificity; Thoracic Neoplasms | 2006 |
[Correlation of 3'-deoxy-3'-18F-fluorothymidine uptake to cell proliferation in lung carcinoma xenografts].
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Cisplatin; Dideoxynucleosides; Female; Fluorine Radioisotopes; Fluorodeoxyglucose F18; Lung Neoplasms; Male; Mice; Mice, Inbred Strains; Neoplasm Transplantation; Positron-Emission Tomography; Proliferating Cell Nuclear Antigen; Tissue Distribution; Xenograft Model Antitumor Assays | 2006 |
Correlation of 18F-FLT and 18F-FDG uptake on PET with Ki-67 immunohistochemistry in non-small cell lung cancer.
Topics: Aged; Aged, 80 and over; Biomarkers, Tumor; Carcinoma, Non-Small-Cell Lung; Dideoxynucleosides; Female; Fluorodeoxyglucose F18; Humans; Ki-67 Antigen; Lung Neoplasms; Male; Middle Aged; Positron-Emission Tomography; Radiopharmaceuticals; Reproducibility of Results; Sensitivity and Specificity; Statistics as Topic | 2007 |
Comparison of (18)F-FLT PET and (18)F-FDG PET for preoperative staging in non-small cell lung cancer.
Topics: Aged; Aged, 80 and over; Carcinoma, Non-Small-Cell Lung; Dideoxynucleosides; Female; Fluorodeoxyglucose F18; Humans; Lung Neoplasms; Male; Middle Aged; Neoplasm Staging; Positron-Emission Tomography; Preoperative Care; Radiopharmaceuticals; Reproducibility of Results; Sensitivity and Specificity | 2008 |
Evaluation of 2'-deoxy-2'-[18F]fluoro-5-methyl-1-beta-L: -arabinofuranosyluracil ([18F]-L: -FMAU) as a PET imaging agent for cellular proliferation: comparison with [18F]-D: -FMAU and [18F]FLT.
Topics: Animals; Arabinofuranosyluracil; Cell Proliferation; Dideoxynucleosides; Fluorine Radioisotopes; Humans; Lung Neoplasms; Mice; Mice, Nude; Neoplasm Invasiveness; Positron-Emission Tomography; Radiopharmaceuticals; Reproducibility of Results; Sensitivity and Specificity | 2008 |
A multicenter clinical trial on the diagnostic value of dual-tracer PET/CT in pulmonary lesions using 3'-deoxy-3'-18F-fluorothymidine and 18F-FDG.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; China; Dideoxynucleosides; Fluorodeoxyglucose F18; Humans; Lung Neoplasms; Middle Aged; Positron-Emission Tomography; Radiopharmaceuticals; Reproducibility of Results; Sensitivity and Specificity; Solitary Pulmonary Nodule; Subtraction Technique; Tomography, X-Ray Computed | 2008 |
Imaging proliferation in vivo with [F-18]FLT and positron emission tomography.
Topics: Animals; Bone Marrow; Carcinoma, Non-Small-Cell Lung; Dideoxynucleosides; Dogs; Fluorine Radioisotopes; Humans; Lung Neoplasms; Neoplasm Staging; Pilot Projects; Tissue Distribution; Tomography, Emission-Computed | 1998 |