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alosetron and Ischemia

alosetron has been researched along with Ischemia in 3 studies

alosetron : A pyrido[4,3-b]indole compound having a 5-methyl-1H-imidazol-4-ylmethyl group at the 2-position.

Ischemia: A hypoperfusion of the BLOOD through an organ or tissue caused by a PATHOLOGIC CONSTRICTION or obstruction of its BLOOD VESSELS, or an absence of BLOOD CIRCULATION.

Research Excerpts

ExcerptRelevanceReference
"Alosetron users did not differ from IBS patients not using alosetron in the incidence of bowel surgery or hospitalized complications of constipation; there were no cases of colonic ischemia."7.72Incidence of colonic ischemia, hospitalized complications of constipation, and bowel surgery in relation to use of alosetron hydrochloride. ( Alfredson, T; Cook, SF; Miller, DP; Sands, BE; Walker, AM, 2003)
"Alosetron is a potent and selective serotonin antagonist that recently became the first Food and Drug Administration-approved agent for diarrhea-predominant IBS."5.31Ischemic colitis during treatment with alosetron. ( Fisher, RS; Friedel, D; Thomas, R, 2001)
" Reports of ischaemic colitis led to restricted use of the approved drug, alosetron."4.84Is there an experimental basis for the development of ischaemic colitis as a result of 5-HT3 antagonist treatment? ( Camilleri, M, 2007)
"Alosetron users did not differ from IBS patients not using alosetron in the incidence of bowel surgery or hospitalized complications of constipation; there were no cases of colonic ischemia."3.72Incidence of colonic ischemia, hospitalized complications of constipation, and bowel surgery in relation to use of alosetron hydrochloride. ( Alfredson, T; Cook, SF; Miller, DP; Sands, BE; Walker, AM, 2003)
"Alosetron is a potent and selective serotonin antagonist that recently became the first Food and Drug Administration-approved agent for diarrhea-predominant IBS."1.31Ischemic colitis during treatment with alosetron. ( Fisher, RS; Friedel, D; Thomas, R, 2001)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Miller, DP1
Alfredson, T1
Cook, SF1
Sands, BE1
Walker, AM1
Camilleri, M1
Friedel, D1
Thomas, R1
Fisher, RS1

Reviews

1 review available for alosetron and Ischemia

ArticleYear
Is there an experimental basis for the development of ischaemic colitis as a result of 5-HT3 antagonist treatment?
    Neurogastroenterology and motility, 2007, Volume: 19, Issue:2

    Topics: Carbolines; Colitis; Diarrhea; Humans; Ischemia; Risk Factors; Serotonin 5-HT3 Receptor Antagonists;

2007

Other Studies

2 other studies available for alosetron and Ischemia

ArticleYear
Incidence of colonic ischemia, hospitalized complications of constipation, and bowel surgery in relation to use of alosetron hydrochloride.
    The American journal of gastroenterology, 2003, Volume: 98, Issue:5

    Topics: Adolescent; Adult; Aged; Carbolines; Child; Child, Preschool; Cohort Studies; Colon; Colonic Disease

2003
Ischemic colitis during treatment with alosetron.
    Gastroenterology, 2001, Volume: 120, Issue:2

    Topics: Carbolines; Colitis; Colonic Diseases, Functional; Colonoscopy; Humans; Ischemia; Male; Middle Aged;

2001