alosetron has been researched along with Inflammatory Bowel Diseases in 3 studies
alosetron : A pyrido[4,3-b]indole compound having a 5-methyl-1H-imidazol-4-ylmethyl group at the 2-position.
Inflammatory Bowel Diseases: Chronic, non-specific inflammation of the GASTROINTESTINAL TRACT. Etiology may be genetic or environmental. This term includes CROHN DISEASE and ULCERATIVE COLITIS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Alosetron does not cause adverse pharmacodynamic effects, is absorbed rapidly after oral administration and is widely distributed throughout tissues after oral or iv." | 2.41 | Pharmacology and clinical experience with alosetron. ( Camilleri, M, 2000) |
| "Visceral hyperalgesia was observed on day 7 but not on day 4." | 1.38 | Experimental colitis alters expression of 5-HT receptors and transient receptor potential vanilloid 1 leading to visceral hypersensitivity in mice. ( Horie, S; Hosoya, T; Lo, MW; Matsumoto, K; Murayama, T; Takayama, H; Tashima, K, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Matsumoto, K | 1 |
| Lo, MW | 1 |
| Hosoya, T | 1 |
| Tashima, K | 1 |
| Takayama, H | 1 |
| Murayama, T | 1 |
| Horie, S | 1 |
| Camilleri, M | 2 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Evaluation of the Duodenal Microbiome in Pediatric Functional Dyspepsia[NCT02340312] | 40 participants (Actual) | Observational | 2015-01-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for alosetron and Inflammatory Bowel Diseases
| Article | Year |
|---|---|
Advances in pharmacological treatments of IBS.
Topics: Anti-Bacterial Agents; Benzyl Compounds; Carbolines; Clonidine; Humans; Indoles; Inflammatory Bowel | 2004 |
Pharmacology and clinical experience with alosetron.
Topics: Animals; Carbolines; Clinical Trials as Topic; Digestive System; Drug Approval; Drug Evaluation, Pre | 2000 |
1 other study available for alosetron and Inflammatory Bowel Diseases
| Article | Year |
|---|---|
Experimental colitis alters expression of 5-HT receptors and transient receptor potential vanilloid 1 leading to visceral hypersensitivity in mice.
Topics: Animals; Carbolines; Dextran Sulfate; Disease Models, Animal; Electromyography; Hyperalgesia; Inflam | 2012 |