Page last updated: 2024-10-22

alosetron and Bowel Diseases, Inflammatory

alosetron has been researched along with Bowel Diseases, Inflammatory in 3 studies

alosetron : A pyrido[4,3-b]indole compound having a 5-methyl-1H-imidazol-4-ylmethyl group at the 2-position.

Research Excerpts

ExcerptRelevanceReference
"Alosetron does not cause adverse pharmacodynamic effects, is absorbed rapidly after oral administration and is widely distributed throughout tissues after oral or iv."2.41Pharmacology and clinical experience with alosetron. ( Camilleri, M, 2000)
"Visceral hyperalgesia was observed on day 7 but not on day 4."1.38Experimental colitis alters expression of 5-HT receptors and transient receptor potential vanilloid 1 leading to visceral hypersensitivity in mice. ( Horie, S; Hosoya, T; Lo, MW; Matsumoto, K; Murayama, T; Takayama, H; Tashima, K, 2012)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (66.67)29.6817
2010's1 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Matsumoto, K1
Lo, MW1
Hosoya, T1
Tashima, K1
Takayama, H1
Murayama, T1
Horie, S1
Camilleri, M2

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Evaluation of the Duodenal Microbiome in Pediatric Functional Dyspepsia[NCT02340312]40 participants (Actual)Observational2015-01-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for alosetron and Bowel Diseases, Inflammatory

ArticleYear
Advances in pharmacological treatments of IBS.
    Journal of pediatric gastroenterology and nutrition, 2004, Volume: 39 Suppl 3

    Topics: Anti-Bacterial Agents; Benzyl Compounds; Carbolines; Clonidine; Humans; Indoles; Inflammatory Bowel

2004
Pharmacology and clinical experience with alosetron.
    Expert opinion on investigational drugs, 2000, Volume: 9, Issue:1

    Topics: Animals; Carbolines; Clinical Trials as Topic; Digestive System; Drug Approval; Drug Evaluation, Pre

2000

Other Studies

1 other study available for alosetron and Bowel Diseases, Inflammatory

ArticleYear
Experimental colitis alters expression of 5-HT receptors and transient receptor potential vanilloid 1 leading to visceral hypersensitivity in mice.
    Laboratory investigation; a journal of technical methods and pathology, 2012, Volume: 92, Issue:5

    Topics: Animals; Carbolines; Dextran Sulfate; Disease Models, Animal; Electromyography; Hyperalgesia; Inflam

2012