alosetron has been researched along with Allodynia in 5 studies
alosetron : A pyrido[4,3-b]indole compound having a 5-methyl-1H-imidazol-4-ylmethyl group at the 2-position.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Visceral hyperalgesia was observed on day 7 but not on day 4." | 1.38 | Experimental colitis alters expression of 5-HT receptors and transient receptor potential vanilloid 1 leading to visceral hypersensitivity in mice. ( Horie, S; Hosoya, T; Lo, MW; Matsumoto, K; Murayama, T; Takayama, H; Tashima, K, 2012) |
| "WA stress led to visceral hyperalgesia 24 h later." | 1.34 | Dual role of 5-HT3 receptors in a rat model of delayed stress-induced visceral hyperalgesia. ( Bradesi, S; Hicks, GA; Lao, L; Lee, K; Mayer, EA; McLean, PG; Winchester, WJ, 2007) |
| "alosetron treated rats failed to demonstrate any alteration in the VMR." | 1.33 | Effects of the 5-HT3 receptor antagonist, alosetron, in a rat model of somatic and visceral hyperalgesia. ( McLean, PG; Miranda, A; Peles, S; Sengupta, JN, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (60.00) | 29.6817 |
| 2010's | 2 (40.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| El-Ayache, N | 1 |
| Galligan, JJ | 1 |
| Li, Z | 1 |
| Zhang, XJ | 1 |
| Xu, HX | 1 |
| Sung, JJ | 1 |
| Bian, ZX | 1 |
| Matsumoto, K | 1 |
| Lo, MW | 1 |
| Hosoya, T | 1 |
| Tashima, K | 1 |
| Takayama, H | 1 |
| Murayama, T | 1 |
| Horie, S | 1 |
| Miranda, A | 1 |
| Peles, S | 1 |
| McLean, PG | 2 |
| Sengupta, JN | 1 |
| Bradesi, S | 1 |
| Lao, L | 1 |
| Winchester, WJ | 1 |
| Lee, K | 1 |
| Hicks, GA | 1 |
| Mayer, EA | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Evaluation of the Duodenal Microbiome in Pediatric Functional Dyspepsia[NCT02340312] | 40 participants (Actual) | Observational | 2015-01-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
5 other studies available for alosetron and Allodynia
| Article | Year |
|---|---|
5-HT
Topics: Animals; Carbolines; Disease Models, Animal; Humans; Hyperalgesia; Hypersensitivity; Irritable Bowel | 2019 |
Intracolonical administration of protease-activated receptor-2 agonists produced visceral hyperalgesia by up-regulating serotonin in the colon of rats.
Topics: Amino Acid Sequence; Animals; Carbolines; Cell Count; Colon; Enterochromaffin Cells; Hyperalgesia; M | 2009 |
Experimental colitis alters expression of 5-HT receptors and transient receptor potential vanilloid 1 leading to visceral hypersensitivity in mice.
Topics: Animals; Carbolines; Dextran Sulfate; Disease Models, Animal; Electromyography; Hyperalgesia; Inflam | 2012 |
Effects of the 5-HT3 receptor antagonist, alosetron, in a rat model of somatic and visceral hyperalgesia.
Topics: Absorption; Animals; Carbolines; Colon; Dilatation, Pathologic; Electromyography; Gastrointestinal M | 2006 |
Dual role of 5-HT3 receptors in a rat model of delayed stress-induced visceral hyperalgesia.
Topics: Acute Disease; Analgesics, Non-Narcotic; Animals; Avoidance Learning; Capsaicin; Carbolines; Cathete | 2007 |