Page last updated: 2024-08-25

almagate and Macular Degeneration

almagate has been researched along with Macular Degeneration in 195 studies

Research

Studies (195)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's127 (65.13)29.6817
2010's67 (34.36)24.3611
2020's1 (0.51)2.80

Authors

AuthorsStudies
Hara, H; Nakamura, S1
Cannon, E1
Castanotto, D; Stein, CA1
Buyse, M; Coart, E; Punt, CJ; Quinaux, E; Saad, ED; Squifflet, P1
Battaglia Parodi, M; Brue, C; Cappello, E; Di Bartolo, E; Furino, C; Giuffrida, S; Imparato, M; Reibaldi, M1
Chilov, M; Nguyen, CL; Oh, LJ; Wei, J; Wong, E1
Levy, M; Yan, AC1
Hawkins, BS; Krzystolik, MG; Lindsley, K; Solomon, SD; Vedula, SS2
de Graeff, PA; Haaijer-Ruskamp, FM; Mol, PG; Piening, S; Straus, SM1
Lin, JS; Lü, YH; Wang, QZ; Yang, HY; Zhu, Y1
Choovuthayakorn, J; Ittipunkul, N; Kunavisarut, P; Pathanapitoon, K; Patikulsila, D; Saenpen, N; Watanachai, N1
Chong, NV; Morjaria, R1
DeCastro Molina, JA; George, PP; Heng, BH1
Alimanovic, E; Cekic, S; Jaksic, V; Kasumovic, SS; Mavija, M; Stamenkovic, M1
Amato, R; Biagi, C; Buccellato, E; Conti, V; Covezzoli, A; Donati, M; Melis, M; Montanaro, N; Motola, D; Pazzi, L; Vaccheri, A; Venegoni, M1
Kim, IK; Yonekawa, Y1
Kobayashi, M; Manabe, S; Ono, A; Shiraga, F; Shiragami, C; Yamashita, A1
Aslankara, H; Kaynak, S; Koçak, N; Selım, A1
Losada, M; Manresa, N; Mulero, J; Zafrilla, P1
Hernandez, FJ; Hernandez, LI; Machado, I; Schafer, T1
Kanwar, JR; Kanwar, R; Sriramoju, B; Veedu, RN1
Fujino, Y; Kawashima, H; Nishida, J; Nomura, Y; Takahashi, H; Yanagi, Y1
Avitabile, T; Bonfiglio, V; Casuccio, A; Cennamo, G; Cillino, S; Furino, C; Longo, A; Pani, L; Parisi, G; Parravano, M; Reibaldi, M; Russo, A; Uva, MG; Xoxi, E1
Feucht, N; Huebner, M; Lohmann, C; Maier, M1
Bautista-Paloma, J; Flores-Moreno, S1
Adamis, AP; Buggage, R; Cunningham, E; Goldbaum, M; Guyer, D; Katz, B; Masonson, H; Patel, M; Singerman, LJ1
Chang, LK; Chiang, A; Sarraf, D; Yu, F1
Atmani, K; Coscas, F; Coscas, G; Soubrane, G1
Qureshi, SH; van Wijngaarden, P1
Beresniak, A; Bisot-Locard, S; Bremond-Gignac, D; Citterio, T; Cohen, SY; Mimoun, G; Quentel, G1
Tano, Y1
Cohen, SY; Coscas, G; Creuzot-Garcher, C; Devin, F; Gaudric, A; Korobelnik, JF; Mauget-Faysse, M; Sahel, JA; Soubrane, G; Souied, E; Tadayoni, R; Weber, M1
Adelman, RA; Lu, F1
Brown, GC; Brown, MM; Ho, AC; Huang, SS; Ip, MS; Recchia, FM; Scott, IU1
Gutfleisch, M; Heimes, B; Lommatzsch, AP; Pauleikhoff, D; Spital, G; Zeimer, M1
Angulo Bocco, MC; Coscas, G; Glacet-Bernard, A; Soubrane, G; Zourdani, A1
Bhisitkul, RB; Fung, AE1
Bakri, SJ; Depperschmidt, E; Fung, AE; Gibson, A; Palanki, R1
Garcia-Layana, A; Giraldez, J; Hernandez-Pastor, LJ; Ortega, A2
Gutfleisch, M; Heimes, B; Lommatzsch, A; Pauleikhoff, D; Spital, G; Zeimer, M1
Hughes, MS; Sang, DN; Shah, GK1
Kurz-Levin, M; Michels, S1
Menon, G; Walters, G1
Jeganathan, VS; Verma, N1
Barakat, MR; Kaiser, PK1
Ciulla, TA; Rosenfeld, PJ1
Castellarin, AA; Driscoll, S; Halperin, LS; Hassan, TS; Klein, KS; Prenner, JL; Roth, D; Walsh, MK1
Esaka, E; Nagaoka, M; Nakane, M; Oishi, M; Tahara, M1
Klettner, A; Roider, J1
Csaky, K; Do, DV1
Da Rocha Gomes, S; Dausse, E; Toulmé, JJ1
Barbosa, A; Beatty, S; Campos, A; Eldem, B; Faria, R; Feucht, N; Grisanti, S; Hykin, P; Kadayifçilar, S; Kolar, P; Maestroni, L; Olea, JL; Rito, L; Saeed, A; Silva, R; Sivaprasad, S; Staurenghi, G1
Bressler, SB1
Thelen, U1
Bass, EB; Bressler, NM; Cassard, SD; Gower, EW; Schein, OD1
Nelson, M1
Goss, TF; Weber, PA; Wirostko, BM; Xu, X; Zlateva, G1
Wiwanitkit, V1
Campbell, S; Friberg, TR; Goldbaum, M; Patel, S; Tolentino, M; Weber, P1
Chen, FK; Ikeji, F; Keane, PA; Ouyang, Y; Patel, PJ; Sadda, SR; Tufail, A; Walsh, AC1
Dietzel, M; Gutfleisch, M; Heimes, B; Lommatzsch, A; Pauleikhoff, D; Spital, G1
Bolz, M; Mitsch, C; Pollreisz, A; Schmidt-Erfurth, U1
Cennamo, G; Cesarano, I; D'Amico, G; De Crecchio, G; Finelli, M; Forte, R1
Chrapek, O; Dusek, L; Jarkovský, J; Kandrnal, V; Pitrová, S; Rehák, J1
Ernest, J; Pitrová, S1
Pracharová, Z; Rehák, J; Simicák, J; Sín, M1
Hovorka, M1
Frenkel, MP; Frenkel, RE; Haji, SA1
Buyse, M1
Joussen, AM; Wong, D1
Babish, JD; Brechner, RJ; Caplan, S; Rosenfeld, PJ1
Kirchhof, B; Pauleikhoff, D1
Arcidiacono, B; Costagliola, C; Morescalchi, F; Parmeggiani, F; Semeraro, F1
Kühn, T1
Acquah, K; Day, S; Grossman, DS; Lee, PP; Mruthyunjaya, P; Sloan, FA1
Bird, A; Dietzel, M; Gutfleisch, M; Heimes, B; Lommatzsch, A; Pauleikhoff, D; Schumacher, M1
De Jong-Hesse, Y; Hendrikse, F; La Heij, EC; Ringens, PJ; Schouten, JS; van der Reis, MI1
Albini, TA; Berrocal, AM; Davis, JL; Dubovy, SR; Flynn, HW; Kovach, JL; Lalwani, GA; Lee, WH; Moshfeghi, AA; Murray, TG; Puliafito, CA; Rosenfeld, PJ; Schwartz, SG; Smiddy, WE1
Choi, DY; Gorin, MB; Hubschman, JP; McCannel, CA; McCannel, TA; Ortube, MC; Sarraf, D1
Grabska-Liberek, I; Jamrozy-Witkowska, A; Jankowska-Lech, I; Kowalska, K; Nowosielska, A; Terelak-Borys, B1
Basile, AS; Hutmacher, M; Kowalski, K; Masayo, O; Nakane, M; Nickens, D; Nielsen, J; Whitfield, L1
Aihara, Y; Fukuda, T; Hashimoto, H; Yanagi, Y1
Huic, M; Zechmeister-Koss, I1
Bodaghi, B; Cochereau, I; Dumarcet, N; Goebel, F; Hajjar, J; Korobelnik, JF1
Heussen, FM; Keane, PA; Mokwa, N; Ouyang, Y; Patel, PJ; Sadda, SR; Tufail, A; Walsh, AC1
Athanasakis, K; Fragoulakis, V; Kyriopoulos, J; Maniadakis, N; Masaoutis, P; Tsiantou, V1
Kang, KN; Lee, YS1
Andréasson, S; Bruun, A; Ghosh, F; Lövestam Adrian, M; Myers, AC; Ponjavic, V1
Chong, V1
Coco, RM; Fernández Muñoz, M; Hernandez, AG; Sanabria, MR1
Dombi, T; Kwok, KK; Sultan, MB1
Buggage, R; Chakravarthy, U; Kwok, K; Staurenghi, G; Tressler, CS1
Chrapek, O; Jakubcová, M; Pracharová, Z; Rehák, J; Simicák, J; Sin, M1
Chrapek, O; Dubska, Z; Dusova, J; Kandrnal, V; Kolar, P; Pitrova, S; Rehak, J; Rencova, E; Rozsival, P; Studnicka, J1
Adamis, AP; Cunningham, ET; Feinsod, M; Gragoudas, ES; Guyer, DR1
Fine, SL; Kirkpatrick, P; Martin, DF1
Coster, DJ; van Wijngaarden, P; Williams, KA1
Schachat, AP1
Morrow, T1
Blaise, P; Foidart, JM; Rakic, JM1
Moshfeghi, AA; Puliafito, CA1
Adamis, AP; Ng, EW2
Doggrell, SA1
Keating, GM; Siddiqui, MA1
Arias Barquet, L1
Hansen, MH; Mortensen, KK; Sjølie, AK1
Haamann, PH; la Cour, M; Larsen, M; Lund-Andersen, H; Sander, B; Villumsen, JE1
Gryziewicz, L1
Pauleikhoff, D1
Canny, MD; De Erkenez, A; Jucker, F; Krilleke, D; Lee, JH; Ng, YS; Pardi, A; Shima, DT1
Blinder, KJ; Hariprasad, SM; Shah, GK1
Uwaydat, SH; Wiggins, MN1
Spaide, R1
Mones, J1
Fraunfelder, FW1
Hussar, DA1
Kourlas, H; Schiller, DS1
Baumal, CR; Duker, JS; Reichel, E; Rogers, AH; Schuman, S1
Spires, RA1
Apte, RS; Blinder, KJ; Dhalla, MS; Hariprasad, SM; Tewari, A1
Adamis, AP; Cunningham, ET; D'Amico, DJ; Guyer, DR; Katz, B; Masonson, HN; Patel, M1
Wang, B; Zhou, B1
Arroyo, JG1
Michels, S; Rosenfeld, PJ; Schmidt-Erfurth, U1
Sears, JE; Singh, RP1
Adamis, AP; Chakravarthy, U; Cunningham, ET; Goldbaum, M; Guyer, DR; Katz, B; Patel, M1
Menéndez de Lucas, JA; Morcillo Laiz, R1
Levin, GM1
Bandello, F; Chakravarthy, U; Chong, V; Creuzot-Garcher, C; Dimitrakos, SA; Korobelnik, JF; Larsen, M; Monés, J; Pauleikhoff, D; Pournaras, CJ; Soubrane, G; Staurenghi, G; Virgili, G; Wolf, S1
D'Amico, DJ; Vavvas, D1
Kaiser, PK2
Fekrat, S; Williams, AJ1
Bhisitkul, RB; Rutar, T1
Goldbaum, M; Katz, B1
Del Priore, LV; Shah, AR1
Lin, RC; Rosenfeld, PJ1
Bailey, C; Imrie, FR1
Behar-Cohen, F; Berdugo, M; Sennlaub, F1
Brown, GC; Brown, HC; Brown, MM; Kindermann, S; Sharma, S1
Bienias, W; Nowak, JZ1
Guyatt, G; Heels-Ansdell, D; Kelly, S; Mills, E1
Ulińska, M1
Clegg, AJ; Colquitt, J; Jones, J; Takeda, AL1
Adamis, AP; Apte, RS; Masonson, H; Modi, M; Patel, M; Whitfield, L1
Frenkel, MP; Frenkel, RE; Mani, L; Toler, AR1
Joussen, AM1
Covell, CA; Graziano, JA; Rich, D; Tobin, KA1
Leys, A; Patel, M; Shah, SN; Zlateva, G1
Holz, FG1
Brubaker, JW; Collins, AT; Joeres, S; Kaplowitz, K; Romano, PW; Sadda, SR; Updike, PG; Walsh, AC1
Liew, G; Mitchell, P; Wong, TY1
Olsen, TW1
Teper, SJ; Wylegała, E1
Goldstein, M; Leibovitch, I; Loewenstein, A; Waisbourd, M1
Vinores, SA1
Dayani, PN; Holekamp, NM; Siddiqi, OK1
Brand, CS; Kelly, S; Maciver, FM; Roskell, N; Wolowacz, SE1
Hassan, TS; Quiram, PA; Williams, GA1
Chang, LK; Flaxel, CJ; Lauer, AK; Sarraf, D1
Bornfeld, N; Jurklies, B; Lipski, A1
Novack, GD1
Avery, RL1
Rosenfeld, PJ1
Kompella, UB1
Adán, A; Casaroli-Marano, RP1
Earnshaw, SR; Moride, Y; Rochon, S1
Feucht, N; Kotliar, KE; Lanzl, IM; Lohmann, CP; Maier, M1
Calvo-González, C; Donate-López, J; Fernández-Pérez, C; García-Feijoó, J; Garcia-Sánchez, J; Leila, M; Reche-Frutos, J1
Ishida, S1
Pountney, D1
Apte, RS1
Eter, N; Meyer, CH1
Eter, N; Helb, HM; Meyer, CH1
Meyer, CH1
Heimann, H; Meyer, CH; Ziemssen, F1
Parier, V; Soubrane, G1
Cohen, AF; Dubois, EA; van Bronswijk, H; van Meurs, JC1
Maiti, A; Natarajan, S; Uparkar, M1
Dadgostar, H; Waheed, N1
Harding, SP; Heimann, H; Kumar, N; Lenfestey, PM; Mahmood, S; Murjaneh, S1
Krzystolik, MG; Vedula, SS1
Clegg, AJ; Colquitt, JL; Jones, J; Price, A; Takeda, A; Tan, SC1
Gajdzik-Gajdecka, U; Smuzyńska, M; Trzciakowski, K; Wykrota, H1

Reviews

64 review(s) available for almagate and Macular Degeneration

ArticleYear
[Prospects and Challenges of Anti-VEGF Drug Treatment for Pathological Angiogenesis of the Retina].
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 2021, Volume: 141, Issue:12

    Topics: Angiogenesis Inhibitors; Animals; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Diabetic Retinopathy; Drug Development; Humans; Macular Degeneration; Mice; Molecular Targeted Therapy; Neovascularization, Pathologic; Ranibizumab; Receptors, Vascular Endothelial Growth Factor; Recombinant Fusion Proteins; Retina; Retinal Vein Occlusion; Vascular Endothelial Growth Factor A

2021
Managed care opportunities and approaches to supporting appropriate selection of treatment for sight preservation.
    The American journal of managed care, 2019, Volume: 25, Issue:10 Suppl

    Topics: Aging; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Bevacizumab; Cost-Benefit Analysis; Humans; Intravitreal Injections; Macular Degeneration; Managed Care Programs; Medicare; Off-Label Use; Pharmaceutical Services; Professional Role; Quality-Adjusted Life Years; Ranibizumab; Receptors, Vascular Endothelial Growth Factor; Recombinant Fusion Proteins; United States; Vascular Endothelial Growth Factor A; Vision Disorders

2019
FDA-Approved Oligonucleotide Therapies in 2017.
    Molecular therapy : the journal of the American Society of Gene Therapy, 2017, 05-03, Volume: 25, Issue:5

    Topics: Aptamers, Nucleotide; Clinical Trials as Topic; Cytomegalovirus Retinitis; Drug Approval; Hepatic Veno-Occlusive Disease; Humans; Hypercholesterolemia; Macular Degeneration; Morpholinos; Muscular Atrophy, Spinal; Muscular Dystrophy, Duchenne; Oligonucleotides; Oligonucleotides, Antisense; Polydeoxyribonucleotides; Thionucleotides

2017
Anti-vascular endothelial growth factor for neovascular age-related macular degeneration: a meta-analysis of randomized controlled trials.
    BMC ophthalmology, 2018, May-30, Volume: 18, Issue:1

    Topics: Angiogenesis Inhibitors; Aptamers, Nucleotide; Bevacizumab; Choroidal Neovascularization; Humans; Intravitreal Injections; Macular Degeneration; Randomized Controlled Trials as Topic; Ranibizumab; Receptors, Vascular Endothelial Growth Factor; Recombinant Fusion Proteins; Vascular Endothelial Growth Factor A; Visual Acuity

2018
Aptamer-Mediated Delivery and Cell-Targeting Aptamers: Room for Improvement.
    Nucleic acid therapeutics, 2018, Volume: 28, Issue:3

    Topics: Aptamers, Nucleotide; Biological Transport; Clinical Trials as Topic; Cytosol; Endosomes; Gene Transfer Techniques; Genetic Therapy; Humans; Macular Degeneration; Oligonucleotides, Antisense; RNA, Small Interfering; SELEX Aptamer Technique; Structure-Activity Relationship

2018
Anti-vascular endothelial growth factor for neovascular age-related macular degeneration.
    The Cochrane database of systematic reviews, 2019, 03-04, Volume: 3

    Topics: Aged; Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Bevacizumab; Choroidal Neovascularization; Humans; Intravitreal Injections; Macular Degeneration; Middle Aged; Randomized Controlled Trials as Topic; Ranibizumab; Vascular Endothelial Growth Factor A; Visual Acuity

2019
[Recent progress of the aptamer-based antiviral drugs].
    Yao xue xue bao = Acta pharmaceutica Sinica, 2013, Volume: 48, Issue:4

    Topics: Antiviral Agents; Aptamers, Nucleotide; Genome, Viral; Hepacivirus; HIV; HIV Reverse Transcriptase; Humans; Macular Degeneration; Neoplasms; Oligodeoxyribonucleotides; RNA, Small Interfering; SELEX Aptamer Technique; Viral Envelope Proteins; Virus Replication

2013
Pharmacokinetic evaluation of pegaptanib octasodium for the treatment of diabetic edema.
    Expert opinion on drug metabolism & toxicology, 2014, Volume: 10, Issue:8

    Topics: Animals; Aptamers, Nucleotide; Cardiovascular Diseases; Diabetic Retinopathy; Humans; Macular Degeneration; Macular Edema; Risk Factors; Vascular Endothelial Growth Factor A; Vision Disorders

2014
The methodological quality of systematic reviews comparing intravitreal bevacizumab and alternates for neovascular age related macular degeneration: A systematic review of reviews.
    Indian journal of ophthalmology, 2014, Volume: 62, Issue:7

    Topics: Angiogenesis Inhibitors; Aptamers, Nucleotide; Bevacizumab; Humans; Intravitreal Injections; Macular Degeneration; Retinal Neovascularization; Vascular Endothelial Growth Factor A

2014
Anti-vascular endothelial growth factor for neovascular age-related macular degeneration.
    The Cochrane database of systematic reviews, 2014, Aug-29, Issue:8

    Topics: Aged; Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Choroidal Neovascularization; Humans; Intravitreal Injections; Macular Degeneration; Middle Aged; Porphyrins; Randomized Controlled Trials as Topic; Ranibizumab; Vascular Endothelial Growth Factor A; Verteporfin; Visual Acuity

2014
Therapeutic modalities of exudative age-related macular degeneration.
    Medicinski arhiv, 2014, Volume: 68, Issue:3

    Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Bevacizumab; Combined Modality Therapy; Humans; Lenses, Intraocular; Macular Degeneration; Radiation, Ionizing; Ranibizumab; Receptors, Vascular Endothelial Growth Factor; Recombinant Fusion Proteins; Vascular Endothelial Growth Factor A

2014
Clinical characteristics and current treatment of age-related macular degeneration.
    Cold Spring Harbor perspectives in medicine, 2014, Oct-03, Volume: 5, Issue:1

    Topics: Aged; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Bevacizumab; Combined Modality Therapy; Drug Therapy, Combination; Humans; Light Coagulation; Macular Degeneration; Middle Aged; Photochemotherapy; Ranibizumab; Receptors, Vascular Endothelial Growth Factor; Recombinant Fusion Proteins; Risk Factors; Vascular Endothelial Growth Factor A

2014
Aptamers overview: selection, features and applications.
    Current topics in medicinal chemistry, 2015, Volume: 15, Issue:12

    Topics: Aptamers, Nucleotide; Biological Assay; Drug Delivery Systems; Drug Discovery; Food Technology; Humans; Macular Degeneration; Molecular Targeted Therapy; Reagent Kits, Diagnostic; SELEX Aptamer Technique; Small Molecule Libraries; Staining and Labeling

2015
Aptamer-targeted oligonucleotide theranostics: a smarter approach for brain delivery and the treatment of neurological diseases.
    Current topics in medicinal chemistry, 2015, Volume: 15, Issue:12

    Topics: Alzheimer Disease; Aptamers, Nucleotide; Aptamers, Peptide; Blood-Brain Barrier; Brain Neoplasms; Drug Delivery Systems; Humans; Macular Degeneration; Molecular Targeted Therapy; Multiple Sclerosis; Myasthenia Gravis; Parkinson Disease; SELEX Aptamer Technique; Stroke; Theranostic Nanomedicine

2015
Inhibitors of vascular endothelial growth factor (VEGF) in the management of neovascular age-related macular degeneration: a review of current practice.
    Clinical & experimental optometry, 2008, Volume: 91, Issue:5

    Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Bevacizumab; Choroidal Neovascularization; Clinical Trials as Topic; Humans; Macular Degeneration; Photochemotherapy; Ranibizumab; Vascular Endothelial Growth Factor A

2008
Anti-vascular endothelial growth factor pharmacotherapy for age-related macular degeneration: a report by the American Academy of Ophthalmology.
    Ophthalmology, 2008, Volume: 115, Issue:10

    Topics: Academies and Institutes; Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Bevacizumab; Choroidal Neovascularization; Drug Therapy; Humans; Macular Degeneration; Ranibizumab; Technology Assessment, Biomedical; Treatment Outcome; United States; Vascular Endothelial Growth Factor A

2008
Verteporfin combination regimens in the treatment of neovascular age-related macular degeneration.
    Retina (Philadelphia, Pa.), 2009, Volume: 29, Issue:2

    Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Bevacizumab; Choroidal Neovascularization; Drug Therapy, Combination; Humans; Macular Degeneration; Photochemotherapy; Photosensitizing Agents; Porphyrins; Ranibizumab; Vascular Endothelial Growth Factor A; Verteporfin

2009
[Age-related macular degeneration (AMD)].
    Therapeutische Umschau. Revue therapeutique, 2009, Volume: 66, Issue:3

    Topics: Adult; Age Factors; Aged; Antioxidants; Aptamers, Nucleotide; Diet; Fluorescein Angiography; Fundus Oculi; Genetic Predisposition to Disease; Humans; Macular Degeneration; Middle Aged; Photochemotherapy; Polymorphism, Genetic; Prevalence; Prospective Studies; Randomized Controlled Trials as Topic; Risk Factors; Smoking; Tomography, Optical Coherence; Vascular Endothelial Growth Factor A; Visual Acuity; Zinc

2009
Safety and efficacy of intravitreal anti-VEGF injections for age-related macular degeneration.
    Current opinion in ophthalmology, 2009, Volume: 20, Issue:3

    Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Bevacizumab; Humans; Injections; Macular Degeneration; Ranibizumab; Treatment Outcome; Vascular Endothelial Growth Factor A; Vitreous Body

2009
VEGF inhibitors for the treatment of neovascular age-related macular degeneration.
    Expert opinion on investigational drugs, 2009, Volume: 18, Issue:5

    Topics: Animals; Aptamers, Nucleotide; Humans; Macular Degeneration; Neovascularization, Pathologic; Treatment Outcome; Vascular Endothelial Growth Factor A

2009
Antivascular endothelial growth factor therapy for neovascular age-related macular degeneration.
    Current opinion in ophthalmology, 2009, Volume: 20, Issue:3

    Topics: Angiogenesis Inhibitors; Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Bevacizumab; Choroidal Neovascularization; Drug Approval; Humans; Macular Degeneration; Ranibizumab; United States; United States Food and Drug Administration; Vascular Endothelial Growth Factor A

2009
Treating age-related macular degeneration - interaction of VEGF-antagonists with their target.
    Mini reviews in medicinal chemistry, 2009, Volume: 9, Issue:9

    Topics: Age Factors; Amino Acid Sequence; Angiogenesis Inhibitors; Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Bevacizumab; Humans; Macular Degeneration; Molecular Sequence Data; Ranibizumab; Receptors, Vascular Endothelial Growth Factor; Recombinant Fusion Proteins; RNA, Small Interfering; Vascular Endothelial Growth Factors

2009
Aptamers: a new class of oligonucleotides in the drug discovery pipeline?
    Current opinion in pharmacology, 2009, Volume: 9, Issue:5

    Topics: Animals; Aptamers, Nucleotide; Drug Discovery; High-Throughput Screening Assays; Humans; Macular Degeneration; Nucleic Acid Conformation; SELEX Aptamer Technique; Small Molecule Libraries; Structure-Activity Relationship; Vascular Endothelial Growth Factor A

2009
Introduction: Understanding the role of angiogenesis and antiangiogenic agents in age-related macular degeneration.
    Ophthalmology, 2009, Volume: 116, Issue:10 Suppl

    Topics: Angiogenesis Inhibitors; Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Bevacizumab; Choroidal Neovascularization; Humans; Macular Degeneration; Ranibizumab; Vascular Endothelial Growth Factor A

2009
Systemic adverse drug reactions secondary to anti-VEGF intravitreal injection in patients with neovascular age-related macular degeneration.
    Current vascular pharmacology, 2011, Volume: 9, Issue:5

    Topics: Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Bevacizumab; Choroidal Neovascularization; Humans; Intravitreal Injections; Ligands; Macular Degeneration; Ranibizumab; Receptors, Vascular Endothelial Growth Factor; Treatment Outcome; Vascular Endothelial Growth Factor A; Visual Acuity

2011
A systematic review of the adverse events of intravitreal anti-vascular endothelial growth factor injections.
    Retina (Philadelphia, Pa.), 2011, Volume: 31, Issue:8

    Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Bevacizumab; Humans; Incidence; Intravitreal Injections; Macular Degeneration; Ranibizumab; Vascular Endothelial Growth Factor A

2011
Vascular endothelial growth factor inhibitors (anti-VEGF) in the management of diabetic macular oedema: a systematic review.
    The British journal of ophthalmology, 2012, Volume: 96, Issue:2

    Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Bevacizumab; Diabetic Retinopathy; Humans; Intravitreal Injections; Macular Degeneration; Macular Edema; Randomized Controlled Trials as Topic; Ranibizumab; Retreatment; Treatment Outcome; Vascular Endothelial Growth Factor A; Visual Acuity

2012
RNA aptamers: a review of recent trends and applications.
    Advances in biochemical engineering/biotechnology, 2013, Volume: 131

    Topics: Aptamers, Nucleotide; Clinical Trials as Topic; Cooperative Behavior; Humans; Inflammation; Ligands; Macular Degeneration; SELEX Aptamer Technique; Social Support; Vascular Endothelial Growth Factor A

2013
Biological, preclinical and clinical characteristics of inhibitors of vascular endothelial growth factors.
    Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde, 2012, Volume: 227 Suppl 1

    Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Bevacizumab; Diabetic Retinopathy; Humans; Macular Degeneration; Macular Edema; Ranibizumab; Receptors, Vascular Endothelial Growth Factor; Recombinant Fusion Proteins; Vascular Endothelial Growth Factor A

2012
Inhibitors of ocular neovascularization: promises and potential problems.
    JAMA, 2005, Mar-23, Volume: 293, Issue:12

    Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Diabetic Retinopathy; Humans; Injections; Macular Degeneration; Oligonucleotides; Ranibizumab; Vascular Endothelial Growth Factor A

2005
Pegaptanib sodium for the treatment of neovascular age-related macular degeneration.
    Expert opinion on investigational drugs, 2005, Volume: 14, Issue:5

    Topics: Aptamers, Nucleotide; Clinical Trials as Topic; Humans; Macular Degeneration; Retinal Neovascularization; Vascular Endothelial Growth Factor A; Vitreous Body

2005
Targeting angiogenesis, the underlying disorder in neovascular age-related macular degeneration.
    Canadian journal of ophthalmology. Journal canadien d'ophtalmologie, 2005, Volume: 40, Issue:3

    Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Bevacizumab; Humans; Macular Degeneration; Neovascularization, Pathologic; Treatment Outcome; Vascular Endothelial Growth Factor A

2005
Pegaptanib: the first antiangiogenic agent approved for neovascular macular degeneration.
    Expert opinion on pharmacotherapy, 2005, Volume: 6, Issue:8

    Topics: Angiogenesis Inhibitors; Animals; Aptamers, Nucleotide; Humans; Macular Degeneration; Neovascularization, Pathologic; Vascular Endothelial Growth Factor A

2005
Pegaptanib: in exudative age-related macular degeneration.
    Drugs, 2005, Volume: 65, Issue:11

    Topics: Animals; Aptamers, Nucleotide; Humans; Injections; Macular Degeneration; Oligonucleotides; Randomized Controlled Trials as Topic; Visual Acuity; Vitreous Body

2005
Regulatory aspects of drug approval for macular degeneration.
    Advanced drug delivery reviews, 2005, Dec-13, Volume: 57, Issue:14

    Topics: Aptamers, Nucleotide; Clinical Trials as Topic; Drug Approval; Drugs, Investigational; Humans; Macular Degeneration; Porphyrins; Treatment Outcome; United States; United States Food and Drug Administration; Vascular Endothelial Growth Factor A; Verteporfin

2005
neovascular age-related macular degeneration: Natural History and Treatment Outcomes.
    Retina (Philadelphia, Pa.), 2005, Volume: 25, Issue:8

    Topics: Aptamers, Nucleotide; Choroidal Neovascularization; Fluorescein Angiography; Humans; Laser Coagulation; Macular Degeneration; Photochemotherapy; Prognosis; Treatment Outcome; Visual Acuity

2005
Pegaptanib sodium for the treatment of neovascular age-related macular degeneration: a review.
    Clinical therapeutics, 2006, Volume: 28, Issue:1

    Topics: Animals; Aptamers, Nucleotide; Choroidal Neovascularization; Humans; Macular Degeneration; Treatment Outcome

2006
How you can help when older eyes fail.
    RN, 2006, Volume: 69, Issue:2

    Topics: Age Distribution; Aged; Aptamers, Nucleotide; Causality; Disease Progression; Humans; Laser Coagulation; Macular Degeneration; Middle Aged; Nurse's Role; Nursing Assessment; Patient Education as Topic; Photochemotherapy; Referral and Consultation; Risk Assessment; United States; Visual Acuity

2006
Pegaptanib for the treatment of age-related macular degeneration.
    Experimental eye research, 2006, Volume: 83, Issue:3

    Topics: Aptamers, Nucleotide; Drug Administration Schedule; Drug Costs; Humans; Macular Degeneration; Models, Animal; Randomized Controlled Trials as Topic; Vascular Endothelial Growth Factor A

2006
Promising new treatments for neovascular age-related macular degeneration.
    Expert opinion on investigational drugs, 2006, Volume: 15, Issue:7

    Topics: Aging; Angiogenesis Inhibitors; Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Bevacizumab; Capillary Permeability; Cholestanols; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Double-Blind Method; Drug Design; Drugs, Investigational; Eye Proteins; Humans; Injections; Lactates; Macular Degeneration; Models, Animal; Multicenter Studies as Topic; Neovascularization, Pathologic; Nerve Growth Factors; Pigment Epithelium of Eye; Protein Isoforms; Randomized Controlled Trials as Topic; RNA Interference; RNA, Small Interfering; Serpins; Stilbenes; Treatment Outcome; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-2; Vitreous Body

2006
Pegaptanib (Macugen): treating neovascular age-related macular degeneration and current role in clinical practice.
    Ophthalmology clinics of North America, 2006, Volume: 19, Issue:3

    Topics: Aptamers, Nucleotide; Humans; Macular Degeneration; Retinal Neovascularization; Treatment Outcome; Vascular Endothelial Growth Factor A

2006
Expanding treatment options in age-related macular degeneration.
    International ophthalmology clinics, 2006,Fall, Volume: 46, Issue:4

    Topics: Aptamers, Nucleotide; Drug Therapy, Combination; Humans; Macular Degeneration; Photochemotherapy; Photosensitizing Agents; Treatment Outcome; Vascular Endothelial Growth Factor A

2006
Macugen (pegaptanib sodium), a novel ocular therapeutic that targets vascular endothelial growth factor (VEGF).
    International ophthalmology clinics, 2006,Fall, Volume: 46, Issue:4

    Topics: Aptamers, Nucleotide; Humans; Macular Degeneration; Retinal Neovascularization; Treatment Outcome; Vascular Endothelial Growth Factor A

2006
Anti-VEGF aptamer (pegaptanib) therapy for ocular vascular diseases.
    Annals of the New York Academy of Sciences, 2006, Volume: 1082

    Topics: Aptamers, Nucleotide; Clinical Trials as Topic; Diabetes Complications; Humans; Macular Degeneration; Macular Edema; Retinal Degeneration; Treatment Outcome; Vascular Endothelial Growth Factor A

2006
Progressive visual loss in subfoveal exudation in age-related macular degeneration: a meta-analysis using Lineweaver-Burke plots.
    American journal of ophthalmology, 2007, Volume: 143, Issue:1

    Topics: Angiogenesis Inhibitors; Aptamers, Nucleotide; Blindness; Choroidal Neovascularization; Disease Progression; Exudates and Transudates; Humans; Macula Lutea; Macular Degeneration; Photochemotherapy; Pregnadienediols; Randomized Controlled Trials as Topic; Retrospective Studies; Vascular Endothelial Growth Factor A; Visual Acuity

2007
Antiangiogenic therapy in neovascular age-related macular degeneration.
    International ophthalmology clinics, 2007,Winter, Volume: 47, Issue:1

    Topics: Angiogenesis Inhibitors; Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Choroidal Neovascularization; Humans; Macular Degeneration; Photochemotherapy; Photosensitizing Agents; Ranibizumab; Treatment Outcome; Vascular Endothelial Growth Factor A

2007
Verteporfin photodynamic therapy and anti-angiogenic drugs: potential for combination therapy in exudative age-related macular degeneration.
    Current medical research and opinion, 2007, Volume: 23, Issue:3

    Topics: Age Factors; Aged; Angiogenesis Inhibitors; Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Choroidal Neovascularization; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Female; Haplorhini; Humans; Macular Degeneration; Male; Middle Aged; Photochemotherapy; Porphyrins; Prognosis; Ranibizumab; Risk Assessment; Treatment Outcome; Verteporfin; Visual Acuity

2007
[Age-related macular degeneration (AMD): etiopathogenesis and therapeutic strategies].
    Postepy higieny i medycyny doswiadczalnej (Online), 2007, Volume: 61

    Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antioxidants; Aptamers, Nucleotide; Bevacizumab; Humans; Lipofuscin; Macular Degeneration; Neovascularization, Pathologic; Photochemotherapy; Pregnadienediols; Ranibizumab; Retinal Drusen; Triamcinolone Acetonide

2007
[Pegaptanib sodium in treatment of wet AMD].
    Klinika oczna, 2006, Volume: 108, Issue:10-12

    Topics: Aptamers, Nucleotide; Humans; Macular Degeneration; Practice Guidelines as Topic; Randomized Controlled Trials as Topic; Retinal Neovascularization; Vascular Endothelial Growth Factor A

2006
Pegaptanib and ranibizumab for neovascular age-related macular degeneration: a systematic review.
    The British journal of ophthalmology, 2007, Volume: 91, Issue:9

    Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Choroidal Neovascularization; Disease Progression; Humans; Macular Degeneration; Randomized Controlled Trials as Topic; Ranibizumab; Treatment Outcome; Vascular Endothelial Growth Factor A; Visual Acuity

2007
[Molecular pathogenesis of ocular vascular disease--anti-angiogenesis as a therapeutic concept].
    Deutsche medizinische Wochenschrift (1946), 2007, Jun-08, Volume: 132, Issue:23

    Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Bevacizumab; Diabetic Angiopathies; Diabetic Retinopathy; Humans; Infant, Newborn; Macular Degeneration; Neovascularization, Pathologic; Ranibizumab; Retinal Diseases; Retinopathy of Prematurity; Vascular Diseases

2007
[VEGF in age-related macular degeneration. Part II. VEGF inhibitors use in age-related macular degeneration treatment].
    Klinika oczna, 2007, Volume: 109, Issue:1-3

    Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Humans; Macular Degeneration; Randomized Controlled Trials as Topic; Ranibizumab; Retina; Treatment Outcome; Vascular Endothelial Growth Factor A

2007
Targeting vascular endothelial growth factor: a promising strategy for treating age-related macular degeneration.
    Drugs & aging, 2007, Volume: 24, Issue:8

    Topics: Aging; Angiogenesis Inhibitors; Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Bevacizumab; Choroidal Neovascularization; Drug Delivery Systems; Humans; Injections; Macular Degeneration; Ranibizumab; Vascular Endothelial Growth Factor A; Visual Acuity; Vitreous Body

2007
Pegaptanib in the treatment of wet, age-related macular degeneration.
    International journal of nanomedicine, 2006, Volume: 1, Issue:3

    Topics: Aptamers, Nucleotide; Choroidal Neovascularization; Clinical Trials as Topic; Humans; Macular Degeneration; Vascular Endothelial Growth Factor A

2006
A view on new drugs for macular degeneration.
    Drug and therapeutics bulletin, 2007, Volume: 45, Issue:7

    Topics: Aged; Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Bevacizumab; Drugs, Investigational; Humans; Macular Degeneration; Ranibizumab

2007
Pharmacotherapy for the treatment of choroidal neovascularization due to age-related macular degeneration.
    Annual review of pharmacology and toxicology, 2008, Volume: 48

    Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Bevacizumab; Choroidal Neovascularization; Humans; Laser Coagulation; Macular Degeneration; Porphyrins; Prevalence; Ranibizumab; Verteporfin

2008
Pegaptanib sodium for the treatment of age-related macular degeneration.
    Expert opinion on pharmacotherapy, 2008, Volume: 9, Issue:3

    Topics: Aged; Angiogenesis Inhibitors; Aptamers, Nucleotide; Choroidal Neovascularization; Humans; Macular Degeneration; Protein Isoforms; Vascular Endothelial Growth Factor A

2008
[Monitoring of AMD patients on anti-vascular endothelial growth factor (VEGF) treatment. Practical notes on functional and anatomical examination parameters from drug approval studies, specialist information and case series].
    Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft, 2008, Volume: 105, Issue:2

    Topics: Aged; Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Bevacizumab; Blindness; Choroidal Neovascularization; Clinical Trials, Phase III as Topic; Fluorescein Angiography; Follow-Up Studies; Humans; Injections; Macular Degeneration; Meta-Analysis as Topic; Monitoring, Physiologic; Multicenter Studies as Topic; Photochemotherapy; Photosensitizing Agents; Porphyrins; Randomized Controlled Trials as Topic; Ranibizumab; Retrospective Studies; Time Factors; Tomography, Optical Coherence; Treatment Outcome; Vascular Endothelial Growth Factor A; Verteporfin; Vision Tests; Visual Acuity; Vitreous Body

2008
[Intravitreal injection. Monitoring to avoid postoperative complications].
    Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft, 2008, Volume: 105, Issue:2

    Topics: Adult; Aged; Angiogenesis Inhibitors; Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Bevacizumab; Cataract; Clinical Trials, Phase III as Topic; Endophthalmitis; Eye Hemorrhage; Female; Fetus; Hallucinations; Humans; Injections; Intraocular Pressure; Macular Degeneration; Mice; Paracentesis; Postoperative Complications; Pregnancy; Rabbits; Randomized Controlled Trials as Topic; Ranibizumab; Retinal Detachment; Uveitis; Vascular Endothelial Growth Factor A; Vitreous Body

2008
[Age-related macular degeneration].
    La Revue de medecine interne, 2008, Volume: 29, Issue:3

    Topics: Age Factors; Aged; Aged, 80 and over; Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Dietary Supplements; Fluorescein Angiography; Humans; Laser Coagulation; Macular Degeneration; Middle Aged; Photochemotherapy; Photosensitizing Agents; Porphyrins; Ranibizumab; Tomography, Optical Coherence; Vascular Endothelial Growth Factor A; Verteporfin

2008
[New drugs; pegaptanib and ranibizumab].
    Nederlands tijdschrift voor geneeskunde, 2008, Jan-12, Volume: 152, Issue:2

    Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Disease Progression; Humans; Macular Degeneration; Ranibizumab; Treatment Outcome; Vascular Endothelial Growth Factor A; Visual Acuity

2008
The evolving role of vascular endothelial growth factor inhibitors in the treatment of neovascular age-related macular degeneration.
    Eye (London, England), 2008, Volume: 22, Issue:6

    Topics: Aged; Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Bevacizumab; Clinical Trials, Phase III as Topic; Corneal Neovascularization; Dose-Response Relationship, Drug; Female; Humans; Macular Degeneration; Male; Practice Guidelines as Topic; Ranibizumab; Tomography, Optical Coherence; Vascular Endothelial Growth Factor A

2008
Antiangiogenic therapy with anti-vascular endothelial growth factor modalities for neovascular age-related macular degeneration.
    The Cochrane database of systematic reviews, 2008, Apr-16, Issue:2

    Topics: Aged; Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Choroidal Neovascularization; Humans; Macular Degeneration; Middle Aged; Porphyrins; Randomized Controlled Trials as Topic; Ranibizumab; Vascular Endothelial Growth Factor A; Verteporfin

2008
Ranibizumab and pegaptanib for the treatment of age-related macular degeneration: a systematic review and economic evaluation.
    Health technology assessment (Winchester, England), 2008, Volume: 12, Issue:16

    Topics: Age Factors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Choroidal Neovascularization; Contrast Sensitivity; Cost-Benefit Analysis; Drug Costs; Humans; Macular Degeneration; Randomized Controlled Trials as Topic; Ranibizumab; Visual Acuity

2008

Trials

21 trial(s) available for almagate and Macular Degeneration

ArticleYear
The Additional Value of an E-Mail to Inform Healthcare Professionals of a Drug Safety Issue: A Randomized Controlled Trial in the Netherlands.
    Drug safety, 2013, Volume: 36, Issue:9

    Topics: Adult; Adverse Drug Reaction Reporting Systems; Aptamers, Nucleotide; Attitude of Health Personnel; Communication; Electronic Mail; Female; Humans; Macular Degeneration; Male; Middle Aged; Netherlands; Ophthalmology; Physicians

2013
Pegaptanib sodium for neovascular age-related macular degeneration: third-year safety results of the VEGF Inhibition Study in Ocular Neovascularisation (VISION) trial.
    The British journal of ophthalmology, 2008, Volume: 92, Issue:12

    Topics: Aged; Aptamers, Nucleotide; Choroidal Neovascularization; Female; Fluorescein Angiography; Humans; Intraocular Pressure; Macular Degeneration; Male; Tonometry, Ocular; Treatment Outcome; Vascular Endothelial Growth Factor A

2008
[Pegaptanib sodium one-year treatment study for neovascular age-related macular degeneration].
    Nippon Ganka Gakkai zasshi, 2008, Volume: 112, Issue:7

    Topics: Aged; Aptamers, Nucleotide; Choroidal Neovascularization; Double-Blind Method; Female; Humans; Injections; Macular Degeneration; Male; Vascular Endothelial Growth Factor A; Visual Acuity; Vitreous Body

2008
[Treatment of vascularised serous pigment epithelium detachment in AMD - observations after changing the intravitreal agent due to lack of response].
    Klinische Monatsblatter fur Augenheilkunde, 2008, Volume: 225, Issue:10

    Topics: Aged; Aptamers, Nucleotide; Dose-Response Relationship, Drug; Female; Humans; Macular Degeneration; Male; Retinal Detachment; Treatment Outcome; Vascular Endothelial Growth Factor A

2008
Pegaptanib sodium as maintenance therapy in neovascular age-related macular degeneration: the LEVEL study.
    The British journal of ophthalmology, 2010, Volume: 94, Issue:12

    Topics: Aged; Angiogenesis Inhibitors; Aptamers, Nucleotide; Cornea; Female; Humans; Macular Degeneration; Male; Middle Aged; Prospective Studies; Tomography, Optical Coherence; Treatment Outcome; Vascular Endothelial Growth Factor A; Visual Acuity; Wet Macular Degeneration

2010
Effects of retinal morphology on contrast sensitivity and reading ability in neovascular age-related macular degeneration.
    Investigative ophthalmology & visual science, 2010, Volume: 51, Issue:11

    Topics: Aged; Aged, 80 and over; Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Bevacizumab; Choroidal Neovascularization; Contrast Sensitivity; Cross-Sectional Studies; Double-Blind Method; Female; Humans; Macular Degeneration; Male; Middle Aged; Photochemotherapy; Reading; Retina; Subretinal Fluid; Tomography, Optical Coherence; Vascular Endothelial Growth Factor A; Visual Acuity

2010
[Long-term efficacy and safety profile of pegaptanib sodium for age-related macular degeneration with choroidal neovascularization--evaluation of extended phase II clinical trial].
    Nippon Ganka Gakkai zasshi, 2011, Volume: 115, Issue:2

    Topics: Aged; Aged, 80 and over; Aptamers, Nucleotide; Choroidal Neovascularization; Female; Humans; Macular Degeneration; Male; Vascular Endothelial Growth Factor A; Visual Acuity

2011
Population pharmacokinetics of pegaptanib in patients with neovascular, age-related macular degeneration.
    Journal of clinical pharmacology, 2012, Volume: 52, Issue:8

    Topics: Aged; Aptamers, Nucleotide; Area Under Curve; Cohort Studies; Female; Humans; Kidney Function Tests; Macular Degeneration; Male; Renal Insufficiency; Vascular Endothelial Growth Factor A; Visual Acuity

2012
Assessment of differential pharmacodynamic effects using optical coherence tomography in neovascular age-related macular degeneration.
    Investigative ophthalmology & visual science, 2012, Volume: 53, Issue:3

    Topics: Aged; Aged, 80 and over; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Bevacizumab; Choroidal Neovascularization; Dose-Response Relationship, Drug; Double-Blind Method; Female; Follow-Up Studies; Humans; Intravitreal Injections; Macular Degeneration; Male; Middle Aged; Retrospective Studies; Tomography, Optical Coherence; Treatment Outcome; Vascular Endothelial Growth Factor A

2012
Retinal pigment epithelium tears in age-related macular degeneration treated with antiangiogenic drugs: a controlled study with long follow-up.
    Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde, 2012, Volume: 228, Issue:2

    Topics: Aged; Aged, 80 and over; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Bevacizumab; Case-Control Studies; Female; Fluorescein Angiography; Follow-Up Studies; Humans; Intravitreal Injections; Macular Degeneration; Male; Middle Aged; Ranibizumab; Retinal Perforations; Retinal Pigment Epithelium; Retrospective Studies; Tomography, Optical Coherence; Vascular Endothelial Growth Factor A; Visual Acuity

2012
A retrospective, pooled data analysis of the safety of pegaptanib sodium in the treatment of age-related macular degeneration in subjects with or without diabetes mellitus.
    BMC ophthalmology, 2012, Aug-08, Volume: 12

    Topics: Aptamers, Nucleotide; Choroidal Neovascularization; Cross-Over Studies; Diabetes Mellitus; Dose-Response Relationship, Drug; Follow-Up Studies; Humans; Macular Degeneration; Retrospective Studies; Treatment Outcome; Vascular Endothelial Growth Factor A

2012
Treating early choroidal neovascularisation with pegaptanib sodium in patients with neovascular age-related macular degeneration: findings of the PERSPECTIVES study.
    The British journal of ophthalmology, 2012, Volume: 96, Issue:10

    Topics: Angiogenesis Inhibitors; Aptamers, Nucleotide; Choroidal Neovascularization; Early Diagnosis; Humans; Macular Degeneration; Middle Aged

2012
Pegaptanib for neovascular age-related macular degeneration.
    The New England journal of medicine, 2004, Dec-30, Volume: 351, Issue:27

    Topics: Aged; Aged, 80 and over; Aptamers, Nucleotide; Choroidal Neovascularization; Double-Blind Method; Female; Humans; Injections; Macular Degeneration; Male; Middle Aged; Oligonucleotides; Photochemotherapy; Prospective Studies; Radiography; Vascular Endothelial Growth Factor A; Visual Acuity; Vitreous Body

2004
[Treatment of neovascular age-related macular degeneration with intravitreal vascular endothelial growth factor inhibitor--secondary publication].
    Ugeskrift for laeger, 2005, Aug-29, Volume: 167, Issue:35

    Topics: Aged; Aged, 80 and over; Angiogenesis Inhibitors; Aptamers, Nucleotide; Choroidal Neovascularization; Female; Fluorescein Angiography; Humans; Injections; Macular Degeneration; Male; Middle Aged; Oligonucleotides; Photochemotherapy; Treatment Outcome; Vascular Endothelial Growth Factors; Visual Acuity; Vitreous Body

2005
Pegaptanib sodium for neovascular age-related macular degeneration: two-year safety results of the two prospective, multicenter, controlled clinical trials.
    Ophthalmology, 2006, Volume: 113, Issue:6

    Topics: Aged; Aged, 80 and over; Aptamers, Nucleotide; Choroidal Neovascularization; Double-Blind Method; Female; Fluorescein Angiography; Humans; Injections; Intraocular Pressure; Macular Degeneration; Male; Middle Aged; Prospective Studies; Treatment Outcome; Vascular Endothelial Growth Factor A; Visual Acuity; Vitreous Body

2006
Year 2 efficacy results of 2 randomized controlled clinical trials of pegaptanib for neovascular age-related macular degeneration.
    Ophthalmology, 2006, Volume: 113, Issue:9

    Topics: Aged; Aged, 80 and over; Aptamers, Nucleotide; Choroidal Neovascularization; Double-Blind Method; Female; Fluorescein Angiography; Humans; Indocyanine Green; Injections; Macular Degeneration; Male; Middle Aged; Prospective Studies; Treatment Outcome; Vascular Endothelial Growth Factor A; Visual Acuity; Vitreous Body

2006
A randomized trial of Pegaptanib sodium for age-related macular degeneration used an innovative design to explore disease-modifying effects.
    Journal of clinical epidemiology, 2007, Volume: 60, Issue:5

    Topics: Aptamers, Nucleotide; Choroidal Neovascularization; Drug Administration Schedule; Humans; Injections; Macular Degeneration; Middle Aged; Prospective Studies; Research Design; Treatment Outcome; Vascular Endothelial Growth Factor A; Visual Acuity; Vitreous Body

2007
Pegaptanib 1-year systemic safety results from a safety-pharmacokinetic trial in patients with neovascular age-related macular degeneration.
    Ophthalmology, 2007, Volume: 114, Issue:9

    Topics: Aged; Aged, 80 and over; Angiogenesis Inhibitors; Aptamers, Nucleotide; Blood Pressure; Choroidal Neovascularization; Double-Blind Method; Female; Half-Life; Humans; Immunoglobulin G; Immunoglobulin M; Injections; Intraocular Pressure; Macular Degeneration; Male; Middle Aged; Prospective Studies; Proteinuria; Vascular Endothelial Growth Factor A; Vitreous Body

2007
Quality of life in patients with age-related macular degeneration: results from the VISION study.
    Eye (London, England), 2008, Volume: 22, Issue:6

    Topics: Aged; Aged, 80 and over; Aptamers, Nucleotide; Choroidal Neovascularization; Female; Humans; Macular Degeneration; Male; Middle Aged; Quality of Life; Sickness Impact Profile; Visual Acuity

2008
Combined Pegaptanib sodium (Macugen) and photodynamic therapy in predominantly classic juxtafoveal choroidal neovascularisation in age related macular degeneration.
    The British journal of ophthalmology, 2008, Volume: 92, Issue:1

    Topics: Aged; Angiogenesis Inhibitors; Aptamers, Nucleotide; Choroidal Neovascularization; Combined Modality Therapy; Female; Humans; Macular Degeneration; Male; Middle Aged; Photochemotherapy; Prospective Studies; Treatment Outcome; Vascular Endothelial Growth Factor A; Visual Acuity

2008
[Pegaptanib sodium in treatment of choroidal neovascularization secondary to age-related macular degeneration. One year results].
    Klinika oczna, 2007, Volume: 109, Issue:10-12

    Topics: Aptamers, Nucleotide; Choroidal Neovascularization; Female; Humans; Macular Degeneration; Male; Prospective Studies; Treatment Outcome

2007

Other Studies

110 other study(ies) available for almagate and Macular Degeneration

ArticleYear
The impact of data errors on the outcome of randomized clinical trials.
    Clinical trials (London, England), 2017, Volume: 14, Issue:5

    Topics: Antineoplastic Agents, Immunological; Aptamers, Nucleotide; Cetuximab; Colorectal Neoplasms; Data Accuracy; Data Interpretation, Statistical; Endpoint Determination; Humans; Macular Degeneration; Observer Variation; Randomized Controlled Trials as Topic; Treatment Outcome

2017
Pegaptanib: choroidal neovascularization in patients with age-related macular degeneration and previous arterial thromboembolic events.
    European journal of ophthalmology, 2018, Volume: 28, Issue:1

    Topics: Aged; Aptamers, Nucleotide; Choroidal Neovascularization; Female; Fluorescein Angiography; Follow-Up Studies; Fundus Oculi; Humans; Intravitreal Injections; Macular Degeneration; Male; Retrospective Studies; Thromboembolism; Tomography, Optical Coherence; Treatment Outcome; Vascular Endothelial Growth Factor A; Visual Acuity; Vitreous Body

2018
The use of intravitreal anti-vascular endothelial growth factor injection and its complications in Chiang Mai University Hospital.
    Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 2013, Volume: 96, Issue:11

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Bevacizumab; Child; Child, Preschool; Diabetic Retinopathy; Female; Hospitals, University; Humans; Infant; Intravitreal Injections; Macular Degeneration; Male; Middle Aged; Ranibizumab; Retinal Vein Occlusion; Retrospective Studies; Thailand; Vascular Endothelial Growth Factor A; Young Adult

2013
Comparative safety profiles of intravitreal bevacizumab, ranibizumab and pegaptanib: the analysis of the WHO database of adverse drug reactions.
    European journal of clinical pharmacology, 2014, Volume: 70, Issue:12

    Topics: Adverse Drug Reaction Reporting Systems; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Bevacizumab; Female; Humans; Intravitreal Injections; Macular Degeneration; Male; Ranibizumab; World Health Organization

2014
Effect of switching therapy to pegaptanib in eyes with the persistent cases of exudative age-related macular degeneration.
    Medicine, 2014, Volume: 93, Issue:18

    Topics: Aged; Aged, 80 and over; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Combined Modality Therapy; Drug Substitution; Exudates and Transudates; Female; Humans; Intravitreal Injections; Macular Degeneration; Macular Edema; Male; Middle Aged; Photochemotherapy; Prospective Studies; Radiography; Ranibizumab; Retina; Retinal Detachment; Tomography, Optical Coherence; Treatment Failure; Visual Acuity

2014
Comparative study of photodynamic therapy monotherapy versus triple management in age-related macular degeneration.
    Turkish journal of medical sciences, 2014, Volume: 44, Issue:5

    Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Bevacizumab; Combined Modality Therapy; Female; Glucocorticoids; Humans; Intravitreal Injections; Macular Degeneration; Male; Photochemotherapy; Treatment Outcome; Triamcinolone; Vascular Endothelial Growth Factor A; Visual Acuity

2014
Influence of anti-VEGF about cardiovascular biomarkers in age related macular degeneration.
    The journal of nutrition, health & aging, 2015, Volume: 19, Issue:2

    Topics: Aged; Aged, 80 and over; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Atherosclerosis; Biomarkers; C-Reactive Protein; Cardiovascular Diseases; Female; Fibrinogen; Homocysteine; Humans; Lipids; Macular Degeneration; Male; Middle Aged; Ranibizumab; Risk Factors; Vascular Endothelial Growth Factor A; Wet Macular Degeneration

2015
Vascular Endothelial Growth Factor (VEGF) Concentration Is Underestimated by Enzyme-Linked Immunosorbent Assay in the Presence of Anti-VEGF Drugs.
    Investigative ophthalmology & visual science, 2016, Volume: 57, Issue:2

    Topics: Angiogenesis Inhibitors; Aptamers, Nucleotide; Bevacizumab; Chemokine CCL2; Enzyme-Linked Immunosorbent Assay; Half-Life; Humans; Intravitreal Injections; Macular Degeneration; Ranibizumab; Reagent Kits, Diagnostic; Receptors, Vascular Endothelial Growth Factor; Recombinant Fusion Proteins; Reproducibility of Results; Vascular Endothelial Growth Factor A; Vitreous Body

2016
Association of neovascular age-related macular degeneration with month and season of birth in Italy.
    Aging, 2016, 12-19, Volume: 9, Issue:1

    Topics: Aged; Aged, 80 and over; Angiogenesis Inhibitors; Aptamers, Nucleotide; Bevacizumab; Female; Humans; Incidence; Italy; Macular Degeneration; Male; Neovascularization, Pathologic; Ranibizumab; Receptors, Vascular Endothelial Growth Factor; Recombinant Fusion Proteins; Registries; Seasons; Treatment Outcome; Vascular Endothelial Growth Factor A

2016
[Clinical experience in the treatment of neovascular age-related macular degeneration with pegaptanib].
    Klinische Monatsblatter fur Augenheilkunde, 2008, Volume: 225, Issue:6

    Topics: Aged; Aged, 80 and over; Aptamers, Nucleotide; Choroidal Neovascularization; Drug Administration Schedule; Female; Fluorescein Angiography; Humans; Injections; Intraocular Pressure; Macular Degeneration; Male; Middle Aged; Retreatment; Vascular Endothelial Growth Factor A; Visual Acuity; Vitreous Body

2008
[Treatment of neovascular age-related macular degeneration: an unresolved matter].
    Archivos de la Sociedad Espanola de Oftalmologia, 2008, Volume: 83, Issue:7

    Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Bevacizumab; Drug Approval; Drug Costs; Europe; Humans; Macular Degeneration; National Health Programs; New Zealand; Porphyrins; Ranibizumab; Spain; State Medicine; United States; Verteporfin

2008
Predictors of anti-VEGF-associated retinal pigment epithelial tear using FA and OCT analysis.
    Retina (Philadelphia, Pa.), 2008, Volume: 28, Issue:9

    Topics: Aged; Aged, 80 and over; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Bevacizumab; Choroidal Neovascularization; Female; Fluorescein Angiography; Humans; Macular Degeneration; Male; Predictive Value of Tests; Ranibizumab; Retinal Detachment; Retinal Perforations; Retinal Pigment Epithelium; Retinal Vessels; Retrospective Studies; Risk Assessment; Tomography, Optical Coherence; Vascular Endothelial Growth Factor A

2008
Pegaptanib sodium for occult choroidal neovascularization in neovascular age-related macular degeneration: a prospective case series.
    Eye (London, England), 2009, Volume: 23, Issue:5

    Topics: Aged; Aged, 80 and over; Aptamers, Nucleotide; Choroidal Neovascularization; Compassionate Use Trials; Female; Fluorescein Angiography; Humans; Macular Degeneration; Male; Middle Aged; Outcome Assessment, Health Care; Prospective Studies; Vascular Endothelial Growth Factor A; Visual Acuity

2009
Cost-effectiveness sequential modeling of ranibizumab versus usual care in age-related macular degeneration.
    Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2008, Volume: 246, Issue:11

    Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Blindness; Computer Simulation; Cost-Benefit Analysis; Decision Trees; Drug Therapy, Combination; Humans; Laser Therapy; Macular Degeneration; Models, Economic; Photosensitizing Agents; Population Surveillance; Porphyrins; Ranibizumab; Treatment Outcome; Verteporfin; Visual Acuity

2008
[Evolving intravitreous injection technique].
    Journal francais d'ophtalmologie, 2008, Volume: 31, Issue:6 Pt 1

    Topics: Adrenal Cortex Hormones; Antibiotic Prophylaxis; Aptamers, Nucleotide; Comorbidity; Contraindications; Drug Hypersensitivity; Eye Infections; Humans; Informed Consent; Injections; Macular Degeneration; Monitoring, Physiologic; Mydriatics; Practice Guidelines as Topic; Pupil; Retinal Artery Occlusion; Tonometry, Ocular; Unnecessary Procedures; Vitreous Body; Vitreous Hemorrhage

2008
Are intravitreal bevacizumab and ranibizumab effective in a rat model of choroidal neovascularization?
    Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2009, Volume: 247, Issue:2

    Topics: Angiogenesis Inhibitors; Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Bevacizumab; Choroidal Neovascularization; Disease Models, Animal; Dose-Response Relationship, Drug; Fluorescein Angiography; Injections; Light Coagulation; Macular Degeneration; Ranibizumab; Rats; Rats, Inbred BN; Vascular Endothelial Growth Factor A; Vitreous Body

2009
[Intravitreous injection: retrospective study on 2028 injections and their side effects].
    Journal francais d'ophtalmologie, 2008, Volume: 31, Issue:7

    Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Cataract; Diabetic Retinopathy; Endophthalmitis; Epiretinal Membrane; Humans; Injections; Macular Degeneration; Macular Edema; Ocular Hypertension; Ranibizumab; Retinal Detachment; Retinal Perforations; Retinal Vein Occlusion; Retrospective Studies; Risk Assessment; Triamcinolone Acetonide; Vitreous Body; Vitreous Hemorrhage

2008
Safety monitoring with ocular anti-vascular endothelial growth factor therapies.
    The British journal of ophthalmology, 2008, Volume: 92, Issue:12

    Topics: Aptamers, Nucleotide; Diabetic Retinopathy; Humans; Macular Degeneration; Macular Edema; Vascular Endothelial Growth Factors

2008
Applying the CONSORT and STROBE statements to evaluate the reporting quality of neovascular age-related macular degeneration studies.
    Ophthalmology, 2009, Volume: 116, Issue:2

    Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Bevacizumab; Choroidal Neovascularization; Guidelines as Topic; Humans; Macular Degeneration; Ophthalmology; Periodicals as Topic; Photochemotherapy; Photosensitizing Agents; Porphyrins; Publishing; Quality Control; Randomized Controlled Trials as Topic; Ranibizumab; Verteporfin

2009
Cost-effectiveness of ranibizumab compared with photodynamic treatment of neovascular age-related macular degeneration.
    Clinical therapeutics, 2008, Volume: 30, Issue:12

    Topics: Aged, 80 and over; Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Choroidal Neovascularization; Cost-Benefit Analysis; Humans; Injections; Insurance, Health, Reimbursement; Macular Degeneration; Markov Chains; Middle Aged; Photochemotherapy; Quality of Life; Ranibizumab; Reproducibility of Results; Spain; Visual Acuity

2008
Serous pigment epithelial detachment in age-related macular degeneration: comparison of different treatments.
    Eye (London, England), 2009, Volume: 23, Issue:12

    Topics: Aged; Aged, 80 and over; Angiogenesis Inhibitors; Anti-Inflammatory Agents; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Bevacizumab; Female; Fluorescein Angiography; Follow-Up Studies; Fovea Centralis; Humans; Immunologic Factors; Intravitreal Injections; Macular Degeneration; Male; Middle Aged; Photochemotherapy; Pigment Epithelium of Eye; Ranibizumab; Retinal Detachment; Retrospective Studies; Tomography, Optical Coherence; Triamcinolone Acetonide; Visual Acuity

2009
New paradigms in the treatment of wet AMD: the impact of anti-VEGF therapy.
    Eye (London, England), 2009, Volume: 23 Suppl 1

    Topics: Ambulatory Care; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Critical Pathways; Early Diagnosis; England; Humans; Macular Degeneration; Physical Examination; Practice Guidelines as Topic; Ranibizumab; Referral and Consultation; Vascular Endothelial Growth Factor A

2009
Endophthalmitis after anti-VEGF injections.
    Ophthalmology, 2009, Volume: 116, Issue:6

    Topics: Angiogenesis Inhibitors; Anti-Bacterial Agents; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Bevacizumab; Cohort Studies; Drug Therapy, Combination; Endophthalmitis; Humans; Injections; Macular Degeneration; Ranibizumab; Risk Factors; Vascular Endothelial Growth Factor A; Vitreous Body

2009
Cost-effectiveness of ranibizumab compared with pegaptanib in neovascular age-related macular degeneration.
    Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2010, Volume: 248, Issue:4

    Topics: Aged; Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Choroidal Neovascularization; Cost-Benefit Analysis; Costs and Cost Analysis; Health Care Costs; Health Services Research; Humans; Macular Degeneration; Markov Chains; Quality-Adjusted Life Years; Ranibizumab; Spain; Visual Acuity

2010
[Application of aptamers to medicine: pharmacological profile and results of clinical trials on pegaptanib sodium (Macugen) for age-related macular degeneration].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 2009, Volume: 134, Issue:2

    Topics: Animals; Aptamers, Nucleotide; Humans; Macular Degeneration; Mice; Receptors, Vascular Endothelial Growth Factor; Vascular Endothelial Growth Factor A

2009
Safety implications of vascular endothelial growth factor blockade for subjects receiving intravitreal anti-vascular endothelial growth factor therapies.
    American journal of ophthalmology, 2009, Volume: 148, Issue:5

    Topics: Adverse Drug Reaction Reporting Systems; Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Bevacizumab; Choroidal Neovascularization; Databases, Factual; Drug Administration Routes; Humans; Macular Degeneration; Medical Records Systems, Computerized; Meta-Analysis as Topic; Product Surveillance, Postmarketing; Ranibizumab; Receptors, Vascular Endothelial Growth Factor; Recombinant Fusion Proteins; Registries; Treatment Outcome; Vascular Endothelial Growth Factor A

2009
Intravitreal pegaptanib sodium for choroidal neovascularisation secondary to age-related macular degeneration: Pan-European experience.
    Eye (London, England), 2010, Volume: 24, Issue:5

    Topics: Aptamers, Nucleotide; Choroidal Neovascularization; Cohort Studies; Humans; Intravitreal Injections; Macular Degeneration; Retrospective Studies; Vascular Endothelial Growth Factors; Visual Acuity

2010
[Clinical experience with pegaptanib in the treatment of age-related macular degeneration (AMD)].
    Klinische Monatsblatter fur Augenheilkunde, 2010, Volume: 227, Issue:1

    Topics: Aged; Aged, 80 and over; Aptamers, Nucleotide; Female; Fluorescein Angiography; Humans; Injections; Intraocular Pressure; Macular Degeneration; Male; Retinal Neovascularization; Vascular Endothelial Growth Factor A; Visual Acuity; Vitreous Body

2010
A cost-effectiveness analysis of three treatments for age-related macular degeneration.
    Retina (Philadelphia, Pa.), 2010, Volume: 30, Issue:2

    Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Choroidal Neovascularization; Cost-Benefit Analysis; Drug Costs; Health Care Costs; Humans; Injections; Macular Degeneration; Models, Economic; Photochemotherapy; Photosensitizing Agents; Porphyrins; Quality of Life; Quality-Adjusted Life Years; Ranibizumab; Treatment Outcome; Vascular Endothelial Growth Factor A; Verteporfin; Visual Acuity; Vitreous Body

2010
Re: Verteporfin combination regimens in the treatment of neovascular age-related macular degeneration.
    Retina (Philadelphia, Pa.), 2010, Volume: 30, Issue:2

    Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Bevacizumab; Choroidal Neovascularization; Drug Therapy, Combination; Humans; Macular Degeneration; Photochemotherapy; Photosensitizing Agents; Porphyrins; Ranibizumab; Vascular Endothelial Growth Factor A; Verteporfin

2010
Newly diagnosed exudative age-related macular degeneration treated with pegaptanib sodium monotherapy in US community-based practices: medical chart review study.
    BMC ophthalmology, 2010, Feb-09, Volume: 10

    Topics: Aged; Aged, 80 and over; Aptamers, Nucleotide; Choroidal Neovascularization; Community Medicine; Drug Administration Schedule; Exudates and Transudates; Female; Fovea Centralis; Humans; Injections, Intraocular; Macular Degeneration; Male; Medical Records; Middle Aged; Professional Practice; Retrospective Studies; Treatment Outcome; United States; Vascular Endothelial Growth Factor A; Visual Acuity; Vitreous Body

2010
Ranibizumab vs. pegaptanib: a cost-effectiveness study?
    Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2010, Volume: 248, Issue:11

    Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Choroidal Neovascularization; Cost-Benefit Analysis; Costs and Cost Analysis; Health Care Costs; Health Services Research; Humans; Macular Degeneration; Quality-Adjusted Life Years; Ranibizumab; Visual Acuity

2010
[Retinal angiomatous proliferation with associated pigment epithelium detachment: anti-VEGF therapy].
    Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft, 2011, Volume: 108, Issue:3

    Topics: Aged; Aged, 80 and over; Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Bevacizumab; Choroidal Neovascularization; Female; Fluorescein Angiography; Follow-Up Studies; Humans; Indocyanine Green; Intravitreal Injections; Macular Degeneration; Male; Ophthalmoscopes; Ranibizumab; Retina; Retinal Detachment; Retinal Neovascularization; Retrospective Studies; Tomography, Optical Coherence; Vascular Endothelial Growth Factor A; Visual Acuity

2011
Antivascular endothelial growth factors in age-related macular degeneration.
    Developments in ophthalmology, 2010, Volume: 46

    Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Bevacizumab; Choroidal Neovascularization; Humans; Injections, Intraocular; Macular Degeneration; Ranibizumab; Vascular Endothelial Growth Factor A; Vitreous Body

2010
Intravitreal triamcinolone, bevacizumab and pegaptanib for occult choroidal neovascularization.
    Acta ophthalmologica, 2010, Volume: 88, Issue:8

    Topics: Aged; Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Bevacizumab; Choroidal Neovascularization; Female; Fluorescein Angiography; Follow-Up Studies; Fovea Centralis; Glucocorticoids; Humans; Intraocular Pressure; Intravitreal Injections; Macular Degeneration; Male; Prognosis; Retreatment; Retrospective Studies; Tomography, Optical Coherence; Triamcinolone Acetonide; Vascular Endothelial Growth Factor A; Visual Acuity

2010
[Exsudative age-related macular degeneration treatment results in patients registered in the nation-wide AMADEUS register].
    Ceska a slovenska oftalmologie : casopis Ceske oftalmologicke spolecnosti a Slovenske oftalmologicke spolecnosti, 2010, Volume: 66, Issue:3

    Topics: Aged; Aged, 80 and over; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Czech Republic; Female; Humans; Macular Degeneration; Male; Middle Aged; Photochemotherapy; Porphyrins; Ranibizumab; Registries; Verteporfin; Visual Acuity

2010
[Reimbursement of medical expenses of the exsudative age-related macular degeneration treatment from the public health insurance].
    Ceska a slovenska oftalmologie : casopis Ceske oftalmologicke spolecnosti a Slovenske oftalmologicke spolecnosti, 2010, Volume: 66, Issue:3

    Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Czech Republic; Humans; Insurance, Health, Reimbursement; Macular Degeneration; Photochemotherapy; Porphyrins; Ranibizumab; Verteporfin

2010
[Sodium pegaptanib and ranibizumab in the treatment of the retinal pigment layer ablation in a patient with age-related macular degeneration--a case report].
    Ceska a slovenska oftalmologie : casopis Ceske oftalmologicke spolecnosti a Slovenske oftalmologicke spolecnosti, 2010, Volume: 66, Issue:3

    Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Female; Fluorescein Angiography; Humans; Intravitreal Injections; Macular Degeneration; Middle Aged; Ranibizumab; Retinal Pigment Epithelium; Tomography, Optical Coherence; Visual Acuity

2010
[The change of the anti-VEGF agent in the treatment of exceptionally active choroidal neovascular membrane in age-related macular degeneration].
    Ceska a slovenska oftalmologie : casopis Ceske oftalmologicke spolecnosti a Slovenske oftalmologicke spolecnosti, 2010, Volume: 66, Issue:3

    Topics: Aged, 80 and over; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Choroidal Neovascularization; Drug Substitution; Fluorescein Angiography; Humans; Intravitreal Injections; Macular Degeneration; Male; Ranibizumab; Tomography, Optical Coherence; Vascular Endothelial Growth Factors

2010
Effect of prophylactic intraocular pressure-lowering medication on intraocular pressure spikes after intravitreal injections.
    Archives of ophthalmology (Chicago, Ill. : 1960), 2010, Volume: 128, Issue:12

    Topics: Aged, 80 and over; Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antihypertensive Agents; Aptamers, Nucleotide; Bevacizumab; Female; Humans; Intraocular Pressure; Intravitreal Injections; Macular Degeneration; Male; Ocular Hypertension; Ranibizumab; Retrospective Studies; Tonometry, Ocular; Vascular Endothelial Growth Factor A; Visual Acuity

2010
Generalized pairwise comparisons of prioritized outcomes in the two-sample problem.
    Statistics in medicine, 2010, Dec-30, Volume: 29, Issue:30

    Topics: Antineoplastic Combined Chemotherapy Protocols; Aptamers, Nucleotide; Colorectal Neoplasms; Disease-Free Survival; Fluorouracil; Humans; Leucovorin; Macular Degeneration; Organoplatinum Compounds; Oxaliplatin; Randomized Controlled Trials as Topic; Statistics as Topic; Treatment Outcome; Visual Acuity

2010
The safety of using anti-VEGF: Is there strength in numbers? Curtis LH, Hammill BG, Schulman KA, Cousins SW (2010) Risks of mortality, myocardial infarction, bleeding, and stroke associated with therapies for age-related macular degeneration. Arch Ophthal
    Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2011, Volume: 249, Issue:2

    Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Bevacizumab; Cause of Death; Hemorrhage; Humans; Macular Degeneration; Myocardial Infarction; Photochemotherapy; Ranibizumab; Risk Factors; Stroke; Vascular Endothelial Growth Factor A

2011
Pharmacotherapy for neovascular age-related macular degeneration: an analysis of the 100% 2008 medicare fee-for-service part B claims file.
    American journal of ophthalmology, 2011, Volume: 151, Issue:5

    Topics: Aged; Aged, 80 and over; Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Bevacizumab; Choroidal Neovascularization; Drug Therapy; Drug Utilization Review; Fee-for-Service Plans; Female; Humans; Intravitreal Injections; Macular Degeneration; Male; Medicare Part B; Middle Aged; Porphyrins; Ranibizumab; Retrospective Studies; United States; Vascular Endothelial Growth Factor A; Verteporfin

2011
Retreatment criteria in anti-VEGF therapy of exudative AMD: critical analysis of present regimes and new morphological definition of "lesion activity".
    Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2011, Volume: 249, Issue:5

    Topics: Algorithms; Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Decision Trees; European Union; Exudates and Transudates; Humans; Macular Degeneration; Practice Guidelines as Topic; Ranibizumab; Recurrence; Retreatment; Vascular Endothelial Growth Factor A; Visual Acuity

2011
[Results of an expert survey on VEGF inhibitors in ophthalmology].
    Klinische Monatsblatter fur Augenheilkunde, 2011, Volume: 228, Issue:7

    Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Bevacizumab; Data Collection; Diabetic Retinopathy; Germany; Humans; Interviews as Topic; Intravitreal Injections; Macular Degeneration; Ophthalmology; Practice Patterns, Physicians'; Ranibizumab; Vascular Endothelial Growth Factor A

2011
Ocular complications after anti-vascular endothelial growth factor therapy in Medicare patients with age-related macular degeneration.
    American journal of ophthalmology, 2011, Volume: 152, Issue:2

    Topics: Aged, 80 and over; Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Bevacizumab; Case-Control Studies; Endophthalmitis; Eye Diseases; Female; Follow-Up Studies; Health Services Research; Humans; Incidence; Intravitreal Injections; Macular Degeneration; Male; Medicare Part B; Proportional Hazards Models; Ranibizumab; Retinal Detachment; Retinal Perforations; Retrospective Studies; United States; Uveitis; Vascular Endothelial Growth Factor A; Vitreous Hemorrhage

2011
Long-term visual outcome of pigment epithelial tears in association with anti-VEGF therapy of pigment epithelial detachment in AMD.
    Eye (London, England), 2011, Volume: 25, Issue:9

    Topics: Aged; Aged, 80 and over; Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Bevacizumab; Female; Fluorescein Angiography; Humans; Intravitreal Injections; Macular Degeneration; Male; Middle Aged; Pigment Epithelium of Eye; Ranibizumab; Retinal Detachment; Retinal Perforations; Tomography, Optical Coherence; Vascular Endothelial Growth Factors; Visual Acuity

2011
Endophthalmitis after intravitreal vascular [corrected] endothelial growth factor antagonists: a six-year experience at a university referral center.
    Retina (Philadelphia, Pa.), 2011, Volume: 31, Issue:4

    Topics: Academic Medical Centers; Aged; Aged, 80 and over; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Aqueous Humor; Bacteria; Bevacizumab; Endophthalmitis; Eye Infections, Bacterial; Female; Humans; Intravitreal Injections; Macular Degeneration; Male; Middle Aged; Ranibizumab; Referral and Consultation; Retrospective Studies; Vascular Endothelial Growth Factor A; Visual Acuity; Vitreous Body

2011
Sustained elevated intraocular pressures after intravitreal injection of bevacizumab, ranibizumab, and pegaptanib.
    Retina (Philadelphia, Pa.), 2011, Volume: 31, Issue:6

    Topics: Aged, 80 and over; Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antihypertensive Agents; Aptamers, Nucleotide; Bevacizumab; Female; Filtering Surgery; Humans; Intraocular Pressure; Intravitreal Injections; Macular Degeneration; Male; Ocular Hypertension; Ranibizumab; Retreatment; Retrospective Studies; Tonometry, Ocular; Vascular Endothelial Growth Factor A; Visual Acuity

2011
[Complications of intravitreal injections--own experience].
    Klinika oczna, 2011, Volume: 113, Issue:4-6

    Topics: Aged; Anti-Inflammatory Agents; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Bevacizumab; Conjunctival Diseases; Diabetic Retinopathy; Endophthalmitis; Eye Diseases; Eye Hemorrhage; Female; Follow-Up Studies; Glucocorticoids; Humans; Inflammation; Intravitreal Injections; Iris Diseases; Macular Degeneration; Macular Edema; Male; Middle Aged; Ocular Hypertension; Poland; Ranibizumab; Retinal Diseases; Retinal Vein Occlusion; Retrospective Studies; Risk Factors; Triamcinolone Acetonide; Visual Acuity

2011
[Cost-effectiveness of ranibizumab, photodynamic therapy and pegaptanib sodium in the treatment of neovascular age-related macular degeneration in Japanese].
    Nippon Ganka Gakkai zasshi, 2011, Volume: 115, Issue:9

    Topics: Aged; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Asian People; Choroidal Neovascularization; Cost-Benefit Analysis; Humans; Macular Degeneration; Male; Photochemotherapy; Ranibizumab; Vascular Endothelial Growth Factor A

2011
[Intravitreal injections: AFSSAPS guide to good practice].
    Journal francais d'ophtalmologie, 2012, Volume: 35, Issue:1

    Topics: Aptamers, Nucleotide; Diabetic Retinopathy; Endophthalmitis; France; Humans; Intravitreal Injections; Macular Degeneration; Ophthalmologic Surgical Procedures; Postoperative Complications; Practice Guidelines as Topic; Retinal Diseases; Retinal Vein Occlusion; Societies, Medical

2012
Cost-effectiveness analysis of ranibizumab versus verteporfin photodynamic therapy, pegaptanib sodium, and best supportive care for the treatment of age-related macular degeneration in Greece.
    Clinical therapeutics, 2012, Volume: 34, Issue:2

    Topics: Aged; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Cost-Benefit Analysis; Health Care Costs; Humans; Macular Degeneration; Markov Chains; Photochemotherapy; Porphyrins; Quality-Adjusted Life Years; Ranibizumab; Verteporfin

2012
Retinal function and morphology in rabbit after intravitreal injection of VEGF inhibitors.
    Current eye research, 2012, Volume: 37, Issue:5

    Topics: Angiogenesis Inhibitors; Animals; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Bevacizumab; Disease Models, Animal; Electroretinography; Immunohistochemistry; Intravitreal Injections; Macular Degeneration; Rabbits; Ranibizumab; Retina; Vascular Endothelial Growth Factor A

2012
[The effect comparison of ranibizumab and sodium pegaptanib on the retinal pigment epithelium ablation size in the treatment of age-related macular degeneration].
    Ceska a slovenska oftalmologie : casopis Ceske oftalmologicke spolecnosti a Slovenske oftalmologicke spolecnosti, 2012, Volume: 68, Issue:2

    Topics: Aged; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Female; Humans; Macular Degeneration; Male; Ranibizumab; Retinal Pigment Epithelium; Tomography, Optical Coherence; Vascular Endothelial Growth Factor A

2012
Effects of treatment change in patients with neovascular age-related macular degeneration; results from the Czech National Registry.
    Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia, 2012, Volume: 156, Issue:4

    Topics: Aged; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Czech Republic; Female; Humans; Macular Degeneration; Male; Ranibizumab; Registries; Retrospective Studies; Treatment Failure

2012
Pegaptanib sodium.
    Nature reviews. Drug discovery, 2005, Volume: 4, Issue:3

    Topics: Aptamers, Nucleotide; Double-Blind Method; Humans; Macular Degeneration; Oligonucleotides; Randomized Controlled Trials as Topic; Treatment Outcome; Vascular Endothelial Growth Factor A

2005
New treatments for age-related macular degeneration.
    Ophthalmology, 2005, Volume: 112, Issue:4

    Topics: Aptamers, Nucleotide; Dietary Supplements; Humans; Laser Coagulation; Macular Degeneration; Oligonucleotides; Ophthalmologic Surgical Procedures; Photochemotherapy; Pregnadienediols

2005
Aptamers: slowing progression of AMD.
    Managed care (Langhorne, Pa.), 2005, Volume: 14, Issue:3

    Topics: Age Factors; Aptamers, Nucleotide; Disease Progression; Humans; Macular Degeneration; Oligonucleotides; United States; Vision, Ocular

2005
Pegaptanib and age-related macular degeneration.
    The New England journal of medicine, 2005, Apr-21, Volume: 352, Issue:16

    Topics: Aptamers, Nucleotide; Choroidal Neovascularization; Dose-Response Relationship, Drug; Humans; Injections; Macular Degeneration; Oligonucleotides; Vitreous Body

2005
New drug treats form of age-related macular degeneration. Macugen inhibits progression of wet AMD and also may restore some vision.
    Health news (Waltham, Mass.), 2005, Volume: 11, Issue:5

    Topics: Aged; Angiogenesis Inhibitors; Aptamers, Nucleotide; Humans; Macular Degeneration; Oligonucleotides

2005
Pegaptanib sodium (Macugen) for macular degeneration.
    The Medical letter on drugs and therapeutics, 2005, Jul-04, Volume: 47, Issue:1212

    Topics: Aptamers, Nucleotide; Humans; Injections; Macular Degeneration; Oligonucleotides; Vision Disorders; Vitreous Body

2005
[Antiangiogenic therapy].
    Archivos de la Sociedad Espanola de Oftalmologia, 2005, Volume: 80, Issue:8

    Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Choroidal Neovascularization; Clinical Trials as Topic; Eye Proteins; Humans; Macular Degeneration; Nerve Growth Factors; Photochemotherapy; Ranibizumab; Serpins; Vascular Endothelial Growth Factor A

2005
[Antiangiogenesis therapy of age-related macular degeneration].
    Ugeskrift for laeger, 2005, Aug-29, Volume: 167, Issue:35

    Topics: Aged; Angiogenesis Inhibitors; Aptamers, Nucleotide; Humans; Injections; Macular Degeneration; Oligonucleotides; Vascular Endothelial Growth Factors; Vitreous Body

2005
A therapeutic aptamer inhibits angiogenesis by specifically targeting the heparin binding domain of VEGF165.
    Proceedings of the National Academy of Sciences of the United States of America, 2005, Dec-27, Volume: 102, Issue:52

    Topics: Aptamers, Nucleotide; Binding Sites; Binding, Competitive; Cells, Cultured; Dimerization; Endothelium, Vascular; Heparin; Humans; Macular Degeneration; Magnetic Resonance Spectroscopy; Models, Molecular; Neovascularization, Pathologic; Pichia; Polyethylene Glycols; Protein Binding; Protein Conformation; Protein Isoforms; Protein Structure, Secondary; Protein Structure, Tertiary; Pyrimidines; RNA; Signal Transduction; Thermodynamics; Vascular Endothelial Growth Factor A

2005
Short-term intraocular pressure trends following intravitreal pegaptanib (Macugen) injection.
    American journal of ophthalmology, 2006, Volume: 141, Issue:1

    Topics: Aptamers, Nucleotide; Humans; Injections; Intraocular Pressure; Macular Degeneration; Retrospective Studies; Tonometry, Ocular; Vitreous Body

2006
Age-related macular degeneration: options for earlier detection and improved treatment.
    The Journal of family practice, 2006, Volume: 55, Issue:1

    Topics: Aged; Aged, 80 and over; Aptamers, Nucleotide; Humans; Hypertension; Low-Level Light Therapy; Macular Degeneration; Risk Factors; Smoking; Visual Acuity; Vitamins

2006
New treatments for AMD.
    Ophthalmology, 2006, Volume: 113, Issue:1

    Topics: Aptamers, Nucleotide; Humans; Macular Degeneration; Vascular Endothelial Growth Factor A

2006
New perspectives on the treatment of age-related macular degeneration.
    Drugs of today (Barcelona, Spain : 1998), 2005, Volume: 41, Issue:11

    Topics: Age Factors; Angiogenesis Inhibitors; Aptamers, Nucleotide; Choroidal Neovascularization; Combined Modality Therapy; Genetic Therapy; Humans; Light Coagulation; Macular Degeneration; Photochemotherapy

2005
Pegaptanib for wet macular degeneration.
    Drugs of today (Barcelona, Spain : 1998), 2005, Volume: 41, Issue:11

    Topics: Age Factors; Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Choroidal Neovascularization; Clinical Trials as Topic; Humans; Light Coagulation; Macular Degeneration; Molecular Structure; Photochemotherapy; Ranibizumab; Vascular Endothelial Growth Factor A; Vitamins

2005
New drugs 06, part I.
    Nursing, 2006, Volume: 36, Issue:2

    Topics: Acamprosate; Adenine Nucleotides; Alcohol Deterrents; Amyloid; Analgesics, Non-Narcotic; Anti-HIV Agents; Antifungal Agents; Antineoplastic Agents; Aptamers, Nucleotide; Arabinonucleosides; Azabicyclo Compounds; Benzofurans; Clofarabine; Drug Approval; Drug Therapy; Drug-Related Side Effects and Adverse Reactions; Echinocandins; Exenatide; Fibroblast Growth Factor 7; Guanine; Humans; Hypoglycemic Agents; Islet Amyloid Polypeptide; Lipopeptides; Lipoproteins; Macular Degeneration; Micafungin; omega-Conotoxins; Patient Education as Topic; Peptides; Peptides, Cyclic; Piperazines; Pyrrolidines; Quinuclidines; Solifenacin Succinate; Stomatitis; Taurine; Tetrahydroisoquinolines; Urinary Incontinence; Venoms

2006
Six-week outcomes after pegaptanib.
    Ophthalmology, 2006, Volume: 113, Issue:3

    Topics: Aptamers, Nucleotide; Humans; Macular Degeneration; Time Factors; Tomography, Optical Coherence; Treatment Outcome; Visual Acuity; Vitreous Body

2006
Retinal pigment epithelial tear following intravitreal pegaptanib sodium.
    American journal of ophthalmology, 2006, Volume: 141, Issue:4

    Topics: Aged; Aptamers, Nucleotide; Choroidal Neovascularization; Female; Fluorescein Angiography; Humans; Indocyanine Green; Injections; Macular Degeneration; Male; Pigment Epithelium of Eye; Retinal Detachment; Retinal Perforations; Tomography, Optical Coherence; Visual Acuity

2006
[Comments on current therapeutic possibilities for neovascular age-related macula degeneration].
    Klinische Monatsblatter fur Augenheilkunde, 2006, Volume: 223, Issue:4

    Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Choroidal Neovascularization; Germany; Glucocorticoids; Humans; Laser Coagulation; Macular Degeneration; Photochemotherapy; Porphyrins; Practice Guidelines as Topic; Practice Patterns, Physicians'; Pregnadienediols; Ranibizumab; Triamcinolone; Verteporfin

2006
A 76-year-old man with macular degeneration.
    JAMA, 2006, May-24, Volume: 295, Issue:20

    Topics: Aged; Angiogenesis Inhibitors; Antioxidants; Aptamers, Nucleotide; Humans; Laser Coagulation; Macular Degeneration; Male; Risk Factors; Vascular Endothelial Growth Factor A

2006
Retinal pigment epithelial tears after pegaptanib injection for exudative age-related macular degeneration.
    American journal of ophthalmology, 2006, Volume: 142, Issue:1

    Topics: Aged; Aptamers, Nucleotide; Exudates and Transudates; Female; Fluorescein Angiography; Humans; Injections; Macular Degeneration; Pigment Epithelium of Eye; Retinal Perforations; Rupture

2006
Macular degeneration. Advances in treatment.
    Mayo Clinic health letter (English ed.), 2006, Volume: 24, Issue:7

    Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antioxidants; Aptamers, Nucleotide; Glucocorticoids; Humans; Light Coagulation; Macular Degeneration; Photochemotherapy; Pregnadienediols; Ranibizumab; Triamcinolone

2006
[Medical and legal issues related to the drugs currently used in the treatment of Age-Related Macular Degeneration (ARMD)].
    Archivos de la Sociedad Espanola de Oftalmologia, 2006, Volume: 81, Issue:7

    Topics: Aptamers, Nucleotide; Drug Utilization; Humans; Macular Degeneration; Photosensitizing Agents; Porphyrins; Spain; Triamcinolone Acetonide; Verteporfin

2006
Readers' responses to "the cost of marginal medicine is too high".
    MedGenMed : Medscape general medicine, 2006, May-15, Volume: 8, Issue:2

    Topics: Aptamers, Nucleotide; Health Care Costs; Humans; Macular Degeneration; Medicare

2006
Evolving European guidance on the medical management of neovascular age related macular degeneration.
    The British journal of ophthalmology, 2006, Volume: 90, Issue:9

    Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Choroidal Neovascularization; Evidence-Based Medicine; Humans; Macular Degeneration; Photochemotherapy; Pregnadienediols; Ranibizumab; Treatment Outcome; Triamcinolone Acetonide

2006
Antivascular endothelial growth factor agents and their development: therapeutic implications in ocular diseases.
    American journal of ophthalmology, 2006, Volume: 142, Issue:4

    Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Bevacizumab; Humans; Macular Degeneration; Ranibizumab; Vascular Endothelial Growth Factor A

2006
Progression of choroidal neovascularization following injection of pegaptanib sodium (macugen) in two eyes with neovascular age-related macular degeneration.
    American journal of ophthalmology, 2006, Volume: 142, Issue:4

    Topics: Aged; Angiogenesis Inhibitors; Aptamers, Nucleotide; Choroidal Neovascularization; Disease Progression; Female; Fluorescein Angiography; Humans; Injections; Macular Degeneration; Male; Middle Aged; Vascular Endothelial Growth Factor A; Vitreous Body

2006
New treatments for age-related macular degeneration.
    Age and ageing, 2007, Volume: 36, Issue:1

    Topics: Aged; Aged, 80 and over; Aging; Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Bevacizumab; Choroidal Neovascularization; Humans; Light Coagulation; Macular Degeneration; Photochemotherapy; Randomized Controlled Trials as Topic; Ranibizumab; Vascular Endothelial Growth Factor A

2007
[Age-related macular degeneration: therapeutic hopes].
    Medecine sciences : M/S, 2007, Volume: 23, Issue:2

    Topics: Age of Onset; Aged; Aged, 80 and over; Aging; Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Bevacizumab; Double-Blind Method; Female; Genetic Predisposition to Disease; Humans; Macular Degeneration; Male; Middle Aged; Multicenter Studies as Topic; Randomized Controlled Trials as Topic; Ranibizumab; Vascular Endothelial Growth Factor A

2007
A value-based medicine comparison of interventions for subfoveal neovascular macular degeneration.
    Ophthalmology, 2007, Volume: 114, Issue:6

    Topics: Aptamers, Nucleotide; Choroidal Neovascularization; Clinical Trials as Topic; Cost of Illness; Cost-Benefit Analysis; Economics, Medical; Evidence-Based Medicine; Fovea Centralis; Health Care Costs; Humans; Laser Coagulation; Macular Degeneration; Photochemotherapy; Photosensitizing Agents; Porphyrins; Quality of Life; Quality-Adjusted Life Years; Verteporfin; Visual Acuity

2007
Intraocular pressure effects of pegaptanib (Macugen) injections in patients with and without glaucoma.
    American journal of ophthalmology, 2007, Volume: 143, Issue:6

    Topics: Aged; Antihypertensive Agents; Aptamers, Nucleotide; Chronic Disease; Glaucoma, Open-Angle; Humans; Injections; Intraocular Pressure; Macular Degeneration; Retrospective Studies; Time Factors; Tonometry, Ocular; Vascular Endothelial Growth Factor A; Vitreous Body

2007
New outlook for age-related macular degeneration.
    Nursing, 2007, Volume: 37, Issue:3

    Topics: Aged; Aging; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Fluorescein Angiography; Humans; Light Coagulation; Macular Degeneration; Nursing Assessment; Patient Education as Topic; Photochemotherapy; Ranibizumab; Tomography, Optical Coherence

2007
[A new drug for macular degeneration. A breakthrough accomplished (interview by Waldtraud Paukstadt)].
    MMW Fortschritte der Medizin, 2007, Jan-18, Volume: 149, Issue:3

    Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Bevacizumab; Drug Costs; Germany; Humans; Macular Degeneration; Ranibizumab; Treatment Outcome

2007
Quantitative comparison of optical coherence tomography after pegaptanib or bevacizumab in neovascular age-related macular degeneration.
    Ophthalmology, 2008, Volume: 115, Issue:2

    Topics: Aged; Aged, 80 and over; Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Bevacizumab; Choroidal Neovascularization; Female; Humans; Injections; Macular Degeneration; Male; Retina; Retrospective Studies; Tomography, Optical Coherence; Treatment Outcome; Vascular Endothelial Growth Factor A; Visual Acuity; Vitreous Body

2008
[Position of the Retinological Society, the German Ophthalmological Society and the Professional Association of Ophthalmologists in Germany on the current therapeutic possibilities for neovascular age-related macular degeneration].
    Klinische Monatsblatter fur Augenheilkunde, 2007, Volume: 224, Issue:7

    Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Bevacizumab; Choroidal Neovascularization; Drug Therapy, Combination; Evidence-Based Medicine; Humans; Macular Degeneration; Ophthalmology; Photochemotherapy; Porphyrins; Pregnadienediols; Ranibizumab; Societies, Medical; Triamcinolone Acetonide; Vascular Endothelial Growth Factor A; Verteporfin

2007
Macular degeneration, patients' groups, and pharma.
    Lancet (London, England), 2007, Jul-21, Volume: 370, Issue:9583

    Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Bevacizumab; Cost-Benefit Analysis; Humans; Macular Degeneration; National Health Programs; Patient Rights; Public Opinion; Ranibizumab; United Kingdom

2007
Clinical update: new treatments for age-related macular degeneration.
    Lancet (London, England), 2007, Jul-21, Volume: 370, Issue:9583

    Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Bevacizumab; Coronary Disease; Half-Life; Humans; Macular Degeneration; Randomized Controlled Trials as Topic; Ranibizumab; Treatment Outcome; Vascular Endothelial Growth Factor A

2007
Treatment of exudative age-related macular degeneration: many factors to consider.
    American journal of ophthalmology, 2007, Volume: 144, Issue:2

    Topics: Angiogenesis Inhibitors; Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Bevacizumab; Cost of Illness; Disease Models, Animal; Drug Costs; Humans; Injections; Macular Degeneration; Ranibizumab; Vascular Endothelial Growth Factor A; Vitreous Body

2007
Safety of intravitreal injections in patients receiving warfarin anticoagulation.
    American journal of ophthalmology, 2007, Volume: 144, Issue:3

    Topics: Aged; Aged, 80 and over; Angiogenesis Inhibitors; Anticoagulants; Aptamers, Nucleotide; Aspirin; Celecoxib; Choroidal Neovascularization; Drug Therapy, Combination; Eye Hemorrhage; Female; Humans; Injections; Macular Degeneration; Male; Middle Aged; Pyrazoles; Retrospective Studies; Sulfonamides; Vascular Endothelial Growth Factor A; Vitreous Body; Warfarin

2007
Cost effectiveness of pegaptanib for the treatment of age-related macular degeneration in the UK.
    PharmacoEconomics, 2007, Volume: 25, Issue:10

    Topics: Age Factors; Aged; Aged, 80 and over; Aptamers, Nucleotide; Clinical Trials as Topic; Cost-Benefit Analysis; Female; Humans; Macular Degeneration; Male; Markov Chains; Middle Aged; Models, Statistical; Quality-Adjusted Life Years; Reproducibility of Results; Sex Factors; Treatment Outcome; United Kingdom; Vascular Endothelial Growth Factor A; Visual Acuity

2007
Treatment of naïve lesions in neovascular age-related macular degeneration with pegaptanib.
    Retina (Philadelphia, Pa.), 2007, Volume: 27, Issue:7

    Topics: Aged; Aged, 80 and over; Angiogenesis Inhibitors; Aptamers, Nucleotide; Choroidal Neovascularization; Female; Fluorescein Angiography; Humans; Injections; Macular Degeneration; Male; Retrospective Studies; Tomography, Optical Coherence; Treatment Outcome; Vascular Endothelial Growth Factor A; Visual Acuity; Vitreous Body

2007
RPE tears after pegaptanib treatment in age-related macular degeneration.
    Retina (Philadelphia, Pa.), 2007, Volume: 27, Issue:7

    Topics: Aged; Aged, 80 and over; Angiogenesis Inhibitors; Aptamers, Nucleotide; Choroidal Neovascularization; Female; Fluorescein Angiography; Humans; Injections; Macular Degeneration; Male; Pigment Epithelium of Eye; Postoperative Complications; Retinal Perforations; Tomography, Optical Coherence; Vascular Endothelial Growth Factor A; Visual Acuity; Vitreous Body

2007
Multifocal electroretinography in patients with exudative amd and intravitreal treatment with pegaptanib sodium.
    Retina (Philadelphia, Pa.), 2007, Volume: 27, Issue:7

    Topics: Aged; Aged, 80 and over; Angiogenesis Inhibitors; Aptamers, Nucleotide; Choroidal Neovascularization; Electroretinography; Exudates and Transudates; Female; Humans; Injections; Macular Degeneration; Male; Middle Aged; Retina; Vascular Endothelial Growth Factor A; Visual Acuity; Vitreous Body

2007
New treatments for age-related macular degeneration.
    Lancet (London, England), 2007, Oct-27, Volume: 370, Issue:9597

    Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Bevacizumab; Dose-Response Relationship, Drug; Humans; Macular Degeneration; Ranibizumab; Vascular Endothelial Growth Factor A

2007
New treatments for age-related macular degeneration.
    Lancet (London, England), 2007, Oct-27, Volume: 370, Issue:9597

    Topics: Angiogenesis Inhibitors; Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Bevacizumab; Humans; Macular Degeneration; Rabbits; Ranibizumab; Reference Values

2007
Drug delivery to the back of the eye.
    Archivos de la Sociedad Espanola de Oftalmologia, 2007, Volume: 82, Issue:11

    Topics: Antiviral Agents; Aptamers, Nucleotide; Clinical Trials, Phase III as Topic; Drug Administration Routes; Drug Delivery Systems; Eye Diseases; Glaucoma; Humans; Injections; Macular Degeneration; Nanoparticles; Oligonucleotides, Antisense; Ophthalmic Solutions; Retinal Diseases; Thionucleotides; Vascular Endothelial Growth Factor A

2007
[New therapeutic aspects in age-related macular degeneration].
    Medicina clinica, 2007, Nov-10, Volume: 129, Issue:17

    Topics: Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Clinical Trials, Phase III as Topic; Disease Progression; Forecasting; Humans; Macular Degeneration; Middle Aged; Multicenter Studies as Topic; Photochemotherapy; Photosensitizing Agents; Porphyrins; Randomized Controlled Trials as Topic; Ranibizumab; Risk Factors; Smoking; Smoking Cessation; Vascular Endothelial Growth Factor A; Verteporfin; Visual Acuity

2007
Cost-effectiveness of pegaptanib compared to photodynamic therapy with verteporfin and to standard care in the treatment of subfoveal wet age-related macular degeneration in Canada.
    Clinical therapeutics, 2007, Volume: 29, Issue:9

    Topics: Aged; Aged, 80 and over; Aptamers, Nucleotide; Canada; Cost-Benefit Analysis; Female; Fovea Centralis; Humans; Laser Coagulation; Macular Degeneration; Male; Models, Econometric; Photochemotherapy; Photosensitizing Agents; Porphyrins; Quality-Adjusted Life Years; Vascular Endothelial Growth Factor A; Verteporfin; Visual Acuity

2007
Intraocular pressure effects of pegaptanib (macugen) injections in patients with and without glaucoma.
    American journal of ophthalmology, 2008, Volume: 145, Issue:1

    Topics: Angiogenesis Inhibitors; Aptamers, Nucleotide; Chronic Disease; Glaucoma, Open-Angle; Humans; Injections; Intraocular Pressure; Macular Degeneration; Tonometry, Ocular; Vascular Endothelial Growth Factor A; Vitreous Body

2008
[The current state and issues of medical treatment for age-related macular degeneration].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 2008, Volume: 131, Issue:1

    Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Bevacizumab; Humans; Macular Degeneration; Ranibizumab; Vascular Endothelial Growth Factors

2008
AMD: out of sight out of mind.
    Nursing older people, 2007, Volume: 19, Issue:10

    Topics: Aged; Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Bevacizumab; Cost-Benefit Analysis; Drug Approval; Drug Costs; Drug Utilization; Geriatric Nursing; Health Promotion; Humans; Macular Degeneration; Nurse's Role; Ophthalmology; Practice Guidelines as Topic; Practice Patterns, Physicians'; Ranibizumab; Risk Factors; State Medicine; Treatment Outcome; United Kingdom

2007
Incidence of ocular hemorrhages in anticoagulated patients receiving repeated intravitreal injections.
    American journal of ophthalmology, 2008, Volume: 145, Issue:2

    Topics: Angiogenesis Inhibitors; Anticoagulants; Aptamers, Nucleotide; Aspirin; Choroidal Neovascularization; Drug Therapy, Combination; Eye Hemorrhage; Humans; Incidence; Injections; Macular Degeneration; Risk Factors; Vascular Endothelial Growth Factor A; Vitreous Body; Warfarin

2008
[Introduction to the topic: anti-VEGF therapy in the management of AMD].
    Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft, 2008, Volume: 105, Issue:2

    Topics: Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Choroidal Neovascularization; Endophthalmitis; Humans; Injections; Macular Degeneration; Postoperative Care; Ranibizumab; Time Factors; Tomography, Optical Coherence; Treatment Outcome; Vascular Endothelial Growth Factor A; Visual Acuity; Vitreous Body

2008
Correspondence.
    Retina (Philadelphia, Pa.), 2008, Volume: 28, Issue:3

    Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Bevacizumab; Choroidal Neovascularization; Humans; Injections; Macular Degeneration; Treatment Outcome; Vascular Endothelial Growth Factor A; Visual Acuity; Vitreous Body

2008
Early response of retinal angiomatous proliferation treated with intravitreal pegaptanib: a retrospective review.
    Eye (London, England), 2009, Volume: 23, Issue:3

    Topics: Aged; Aged, 80 and over; Angiogenesis Inhibitors; Angiomatosis; Aptamers, Nucleotide; Drug Evaluation; Female; Follow-Up Studies; Humans; Injections, Intraocular; Macular Degeneration; Male; Middle Aged; Retinal Diseases; Retrospective Studies; Vascular Endothelial Growth Factor A; Visual Acuity

2009