Page last updated: 2024-08-25

almagate and Age-Related Macular Degeneration

almagate has been researched along with Age-Related Macular Degeneration in 195 studies

Research

Studies (195)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's127 (65.13)29.6817
2010's67 (34.36)24.3611
2020's1 (0.51)2.80

Authors

AuthorsStudies
Hara, H; Nakamura, S1
Cannon, E1
Castanotto, D; Stein, CA1
Buyse, M; Coart, E; Punt, CJ; Quinaux, E; Saad, ED; Squifflet, P1
Battaglia Parodi, M; Brue, C; Cappello, E; Di Bartolo, E; Furino, C; Giuffrida, S; Imparato, M; Reibaldi, M1
Chilov, M; Nguyen, CL; Oh, LJ; Wei, J; Wong, E1
Levy, M; Yan, AC1
Hawkins, BS; Krzystolik, MG; Lindsley, K; Solomon, SD; Vedula, SS2
de Graeff, PA; Haaijer-Ruskamp, FM; Mol, PG; Piening, S; Straus, SM1
Lin, JS; Lü, YH; Wang, QZ; Yang, HY; Zhu, Y1
Choovuthayakorn, J; Ittipunkul, N; Kunavisarut, P; Pathanapitoon, K; Patikulsila, D; Saenpen, N; Watanachai, N1
Chong, NV; Morjaria, R1
DeCastro Molina, JA; George, PP; Heng, BH1
Alimanovic, E; Cekic, S; Jaksic, V; Kasumovic, SS; Mavija, M; Stamenkovic, M1
Amato, R; Biagi, C; Buccellato, E; Conti, V; Covezzoli, A; Donati, M; Melis, M; Montanaro, N; Motola, D; Pazzi, L; Vaccheri, A; Venegoni, M1
Kim, IK; Yonekawa, Y1
Kobayashi, M; Manabe, S; Ono, A; Shiraga, F; Shiragami, C; Yamashita, A1
Aslankara, H; Kaynak, S; Koçak, N; Selım, A1
Losada, M; Manresa, N; Mulero, J; Zafrilla, P1
Hernandez, FJ; Hernandez, LI; Machado, I; Schafer, T1
Kanwar, JR; Kanwar, R; Sriramoju, B; Veedu, RN1
Fujino, Y; Kawashima, H; Nishida, J; Nomura, Y; Takahashi, H; Yanagi, Y1
Avitabile, T; Bonfiglio, V; Casuccio, A; Cennamo, G; Cillino, S; Furino, C; Longo, A; Pani, L; Parisi, G; Parravano, M; Reibaldi, M; Russo, A; Uva, MG; Xoxi, E1
Feucht, N; Huebner, M; Lohmann, C; Maier, M1
Bautista-Paloma, J; Flores-Moreno, S1
Adamis, AP; Buggage, R; Cunningham, E; Goldbaum, M; Guyer, D; Katz, B; Masonson, H; Patel, M; Singerman, LJ1
Chang, LK; Chiang, A; Sarraf, D; Yu, F1
Atmani, K; Coscas, F; Coscas, G; Soubrane, G1
Qureshi, SH; van Wijngaarden, P1
Beresniak, A; Bisot-Locard, S; Bremond-Gignac, D; Citterio, T; Cohen, SY; Mimoun, G; Quentel, G1
Tano, Y1
Cohen, SY; Coscas, G; Creuzot-Garcher, C; Devin, F; Gaudric, A; Korobelnik, JF; Mauget-Faysse, M; Sahel, JA; Soubrane, G; Souied, E; Tadayoni, R; Weber, M1
Adelman, RA; Lu, F1
Brown, GC; Brown, MM; Ho, AC; Huang, SS; Ip, MS; Recchia, FM; Scott, IU1
Gutfleisch, M; Heimes, B; Lommatzsch, AP; Pauleikhoff, D; Spital, G; Zeimer, M1
Angulo Bocco, MC; Coscas, G; Glacet-Bernard, A; Soubrane, G; Zourdani, A1
Bhisitkul, RB; Fung, AE1
Bakri, SJ; Depperschmidt, E; Fung, AE; Gibson, A; Palanki, R1
Garcia-Layana, A; Giraldez, J; Hernandez-Pastor, LJ; Ortega, A2
Gutfleisch, M; Heimes, B; Lommatzsch, A; Pauleikhoff, D; Spital, G; Zeimer, M1
Hughes, MS; Sang, DN; Shah, GK1
Kurz-Levin, M; Michels, S1
Menon, G; Walters, G1
Jeganathan, VS; Verma, N1
Barakat, MR; Kaiser, PK1
Ciulla, TA; Rosenfeld, PJ1
Castellarin, AA; Driscoll, S; Halperin, LS; Hassan, TS; Klein, KS; Prenner, JL; Roth, D; Walsh, MK1
Esaka, E; Nagaoka, M; Nakane, M; Oishi, M; Tahara, M1
Klettner, A; Roider, J1
Csaky, K; Do, DV1
Da Rocha Gomes, S; Dausse, E; Toulmé, JJ1
Barbosa, A; Beatty, S; Campos, A; Eldem, B; Faria, R; Feucht, N; Grisanti, S; Hykin, P; Kadayifçilar, S; Kolar, P; Maestroni, L; Olea, JL; Rito, L; Saeed, A; Silva, R; Sivaprasad, S; Staurenghi, G1
Bressler, SB1
Thelen, U1
Bass, EB; Bressler, NM; Cassard, SD; Gower, EW; Schein, OD1
Nelson, M1
Goss, TF; Weber, PA; Wirostko, BM; Xu, X; Zlateva, G1
Wiwanitkit, V1
Campbell, S; Friberg, TR; Goldbaum, M; Patel, S; Tolentino, M; Weber, P1
Chen, FK; Ikeji, F; Keane, PA; Ouyang, Y; Patel, PJ; Sadda, SR; Tufail, A; Walsh, AC1
Dietzel, M; Gutfleisch, M; Heimes, B; Lommatzsch, A; Pauleikhoff, D; Spital, G1
Bolz, M; Mitsch, C; Pollreisz, A; Schmidt-Erfurth, U1
Cennamo, G; Cesarano, I; D'Amico, G; De Crecchio, G; Finelli, M; Forte, R1
Chrapek, O; Dusek, L; Jarkovský, J; Kandrnal, V; Pitrová, S; Rehák, J1
Ernest, J; Pitrová, S1
Pracharová, Z; Rehák, J; Simicák, J; Sín, M1
Hovorka, M1
Frenkel, MP; Frenkel, RE; Haji, SA1
Buyse, M1
Joussen, AM; Wong, D1
Babish, JD; Brechner, RJ; Caplan, S; Rosenfeld, PJ1
Kirchhof, B; Pauleikhoff, D1
Arcidiacono, B; Costagliola, C; Morescalchi, F; Parmeggiani, F; Semeraro, F1
Kühn, T1
Acquah, K; Day, S; Grossman, DS; Lee, PP; Mruthyunjaya, P; Sloan, FA1
Bird, A; Dietzel, M; Gutfleisch, M; Heimes, B; Lommatzsch, A; Pauleikhoff, D; Schumacher, M1
De Jong-Hesse, Y; Hendrikse, F; La Heij, EC; Ringens, PJ; Schouten, JS; van der Reis, MI1
Albini, TA; Berrocal, AM; Davis, JL; Dubovy, SR; Flynn, HW; Kovach, JL; Lalwani, GA; Lee, WH; Moshfeghi, AA; Murray, TG; Puliafito, CA; Rosenfeld, PJ; Schwartz, SG; Smiddy, WE1
Choi, DY; Gorin, MB; Hubschman, JP; McCannel, CA; McCannel, TA; Ortube, MC; Sarraf, D1
Grabska-Liberek, I; Jamrozy-Witkowska, A; Jankowska-Lech, I; Kowalska, K; Nowosielska, A; Terelak-Borys, B1
Basile, AS; Hutmacher, M; Kowalski, K; Masayo, O; Nakane, M; Nickens, D; Nielsen, J; Whitfield, L1
Aihara, Y; Fukuda, T; Hashimoto, H; Yanagi, Y1
Huic, M; Zechmeister-Koss, I1
Bodaghi, B; Cochereau, I; Dumarcet, N; Goebel, F; Hajjar, J; Korobelnik, JF1
Heussen, FM; Keane, PA; Mokwa, N; Ouyang, Y; Patel, PJ; Sadda, SR; Tufail, A; Walsh, AC1
Athanasakis, K; Fragoulakis, V; Kyriopoulos, J; Maniadakis, N; Masaoutis, P; Tsiantou, V1
Kang, KN; Lee, YS1
Andréasson, S; Bruun, A; Ghosh, F; Lövestam Adrian, M; Myers, AC; Ponjavic, V1
Chong, V1
Coco, RM; Fernández Muñoz, M; Hernandez, AG; Sanabria, MR1
Dombi, T; Kwok, KK; Sultan, MB1
Buggage, R; Chakravarthy, U; Kwok, K; Staurenghi, G; Tressler, CS1
Chrapek, O; Jakubcová, M; Pracharová, Z; Rehák, J; Simicák, J; Sin, M1
Chrapek, O; Dubska, Z; Dusova, J; Kandrnal, V; Kolar, P; Pitrova, S; Rehak, J; Rencova, E; Rozsival, P; Studnicka, J1
Adamis, AP; Cunningham, ET; Feinsod, M; Gragoudas, ES; Guyer, DR1
Fine, SL; Kirkpatrick, P; Martin, DF1
Coster, DJ; van Wijngaarden, P; Williams, KA1
Schachat, AP1
Morrow, T1
Blaise, P; Foidart, JM; Rakic, JM1
Moshfeghi, AA; Puliafito, CA1
Adamis, AP; Ng, EW2
Doggrell, SA1
Keating, GM; Siddiqui, MA1
Arias Barquet, L1
Hansen, MH; Mortensen, KK; Sjølie, AK1
Haamann, PH; la Cour, M; Larsen, M; Lund-Andersen, H; Sander, B; Villumsen, JE1
Gryziewicz, L1
Pauleikhoff, D1
Canny, MD; De Erkenez, A; Jucker, F; Krilleke, D; Lee, JH; Ng, YS; Pardi, A; Shima, DT1
Blinder, KJ; Hariprasad, SM; Shah, GK1
Uwaydat, SH; Wiggins, MN1
Spaide, R1
Mones, J1
Fraunfelder, FW1
Hussar, DA1
Kourlas, H; Schiller, DS1
Baumal, CR; Duker, JS; Reichel, E; Rogers, AH; Schuman, S1
Spires, RA1
Apte, RS; Blinder, KJ; Dhalla, MS; Hariprasad, SM; Tewari, A1
Adamis, AP; Cunningham, ET; D'Amico, DJ; Guyer, DR; Katz, B; Masonson, HN; Patel, M1
Wang, B; Zhou, B1
Arroyo, JG1
Michels, S; Rosenfeld, PJ; Schmidt-Erfurth, U1
Sears, JE; Singh, RP1
Adamis, AP; Chakravarthy, U; Cunningham, ET; Goldbaum, M; Guyer, DR; Katz, B; Patel, M1
Menéndez de Lucas, JA; Morcillo Laiz, R1
Levin, GM1
Bandello, F; Chakravarthy, U; Chong, V; Creuzot-Garcher, C; Dimitrakos, SA; Korobelnik, JF; Larsen, M; Monés, J; Pauleikhoff, D; Pournaras, CJ; Soubrane, G; Staurenghi, G; Virgili, G; Wolf, S1
D'Amico, DJ; Vavvas, D1
Kaiser, PK2
Fekrat, S; Williams, AJ1
Bhisitkul, RB; Rutar, T1
Goldbaum, M; Katz, B1
Del Priore, LV; Shah, AR1
Lin, RC; Rosenfeld, PJ1
Bailey, C; Imrie, FR1
Behar-Cohen, F; Berdugo, M; Sennlaub, F1
Brown, GC; Brown, HC; Brown, MM; Kindermann, S; Sharma, S1
Bienias, W; Nowak, JZ1
Guyatt, G; Heels-Ansdell, D; Kelly, S; Mills, E1
Ulińska, M1
Clegg, AJ; Colquitt, J; Jones, J; Takeda, AL1
Adamis, AP; Apte, RS; Masonson, H; Modi, M; Patel, M; Whitfield, L1
Frenkel, MP; Frenkel, RE; Mani, L; Toler, AR1
Joussen, AM1
Covell, CA; Graziano, JA; Rich, D; Tobin, KA1
Leys, A; Patel, M; Shah, SN; Zlateva, G1
Holz, FG1
Brubaker, JW; Collins, AT; Joeres, S; Kaplowitz, K; Romano, PW; Sadda, SR; Updike, PG; Walsh, AC1
Liew, G; Mitchell, P; Wong, TY1
Olsen, TW1
Teper, SJ; Wylegała, E1
Goldstein, M; Leibovitch, I; Loewenstein, A; Waisbourd, M1
Vinores, SA1
Dayani, PN; Holekamp, NM; Siddiqi, OK1
Brand, CS; Kelly, S; Maciver, FM; Roskell, N; Wolowacz, SE1
Hassan, TS; Quiram, PA; Williams, GA1
Chang, LK; Flaxel, CJ; Lauer, AK; Sarraf, D1
Bornfeld, N; Jurklies, B; Lipski, A1
Novack, GD1
Avery, RL1
Rosenfeld, PJ1
Kompella, UB1
Adán, A; Casaroli-Marano, RP1
Earnshaw, SR; Moride, Y; Rochon, S1
Feucht, N; Kotliar, KE; Lanzl, IM; Lohmann, CP; Maier, M1
Calvo-González, C; Donate-López, J; Fernández-Pérez, C; García-Feijoó, J; Garcia-Sánchez, J; Leila, M; Reche-Frutos, J1
Ishida, S1
Pountney, D1
Apte, RS1
Eter, N; Meyer, CH1
Eter, N; Helb, HM; Meyer, CH1
Meyer, CH1
Heimann, H; Meyer, CH; Ziemssen, F1
Parier, V; Soubrane, G1
Cohen, AF; Dubois, EA; van Bronswijk, H; van Meurs, JC1
Maiti, A; Natarajan, S; Uparkar, M1
Dadgostar, H; Waheed, N1
Harding, SP; Heimann, H; Kumar, N; Lenfestey, PM; Mahmood, S; Murjaneh, S1
Krzystolik, MG; Vedula, SS1
Clegg, AJ; Colquitt, JL; Jones, J; Price, A; Takeda, A; Tan, SC1
Gajdzik-Gajdecka, U; Smuzyńska, M; Trzciakowski, K; Wykrota, H1

Reviews

64 review(s) available for almagate and Age-Related Macular Degeneration

ArticleYear
[Prospects and Challenges of Anti-VEGF Drug Treatment for Pathological Angiogenesis of the Retina].
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 2021, Volume: 141, Issue:12

    Topics: Angiogenesis Inhibitors; Animals; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Diabetic Retinopathy; Drug Development; Humans; Macular Degeneration; Mice; Molecular Targeted Therapy; Neovascularization, Pathologic; Ranibizumab; Receptors, Vascular Endothelial Growth Factor; Recombinant Fusion Proteins; Retina; Retinal Vein Occlusion; Vascular Endothelial Growth Factor A

2021
Managed care opportunities and approaches to supporting appropriate selection of treatment for sight preservation.
    The American journal of managed care, 2019, Volume: 25, Issue:10 Suppl

    Topics: Aging; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Bevacizumab; Cost-Benefit Analysis; Humans; Intravitreal Injections; Macular Degeneration; Managed Care Programs; Medicare; Off-Label Use; Pharmaceutical Services; Professional Role; Quality-Adjusted Life Years; Ranibizumab; Receptors, Vascular Endothelial Growth Factor; Recombinant Fusion Proteins; United States; Vascular Endothelial Growth Factor A; Vision Disorders

2019
FDA-Approved Oligonucleotide Therapies in 2017.
    Molecular therapy : the journal of the American Society of Gene Therapy, 2017, 05-03, Volume: 25, Issue:5

    Topics: Aptamers, Nucleotide; Clinical Trials as Topic; Cytomegalovirus Retinitis; Drug Approval; Hepatic Veno-Occlusive Disease; Humans; Hypercholesterolemia; Macular Degeneration; Morpholinos; Muscular Atrophy, Spinal; Muscular Dystrophy, Duchenne; Oligonucleotides; Oligonucleotides, Antisense; Polydeoxyribonucleotides; Thionucleotides

2017
Anti-vascular endothelial growth factor for neovascular age-related macular degeneration: a meta-analysis of randomized controlled trials.
    BMC ophthalmology, 2018, May-30, Volume: 18, Issue:1

    Topics: Angiogenesis Inhibitors; Aptamers, Nucleotide; Bevacizumab; Choroidal Neovascularization; Humans; Intravitreal Injections; Macular Degeneration; Randomized Controlled Trials as Topic; Ranibizumab; Receptors, Vascular Endothelial Growth Factor; Recombinant Fusion Proteins; Vascular Endothelial Growth Factor A; Visual Acuity

2018
Aptamer-Mediated Delivery and Cell-Targeting Aptamers: Room for Improvement.
    Nucleic acid therapeutics, 2018, Volume: 28, Issue:3

    Topics: Aptamers, Nucleotide; Biological Transport; Clinical Trials as Topic; Cytosol; Endosomes; Gene Transfer Techniques; Genetic Therapy; Humans; Macular Degeneration; Oligonucleotides, Antisense; RNA, Small Interfering; SELEX Aptamer Technique; Structure-Activity Relationship

2018
Anti-vascular endothelial growth factor for neovascular age-related macular degeneration.
    The Cochrane database of systematic reviews, 2019, 03-04, Volume: 3

    Topics: Aged; Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Bevacizumab; Choroidal Neovascularization; Humans; Intravitreal Injections; Macular Degeneration; Middle Aged; Randomized Controlled Trials as Topic; Ranibizumab; Vascular Endothelial Growth Factor A; Visual Acuity

2019
[Recent progress of the aptamer-based antiviral drugs].
    Yao xue xue bao = Acta pharmaceutica Sinica, 2013, Volume: 48, Issue:4

    Topics: Antiviral Agents; Aptamers, Nucleotide; Genome, Viral; Hepacivirus; HIV; HIV Reverse Transcriptase; Humans; Macular Degeneration; Neoplasms; Oligodeoxyribonucleotides; RNA, Small Interfering; SELEX Aptamer Technique; Viral Envelope Proteins; Virus Replication

2013
Pharmacokinetic evaluation of pegaptanib octasodium for the treatment of diabetic edema.
    Expert opinion on drug metabolism & toxicology, 2014, Volume: 10, Issue:8

    Topics: Animals; Aptamers, Nucleotide; Cardiovascular Diseases; Diabetic Retinopathy; Humans; Macular Degeneration; Macular Edema; Risk Factors; Vascular Endothelial Growth Factor A; Vision Disorders

2014
The methodological quality of systematic reviews comparing intravitreal bevacizumab and alternates for neovascular age related macular degeneration: A systematic review of reviews.
    Indian journal of ophthalmology, 2014, Volume: 62, Issue:7

    Topics: Angiogenesis Inhibitors; Aptamers, Nucleotide; Bevacizumab; Humans; Intravitreal Injections; Macular Degeneration; Retinal Neovascularization; Vascular Endothelial Growth Factor A

2014
Anti-vascular endothelial growth factor for neovascular age-related macular degeneration.
    The Cochrane database of systematic reviews, 2014, Aug-29, Issue:8

    Topics: Aged; Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Choroidal Neovascularization; Humans; Intravitreal Injections; Macular Degeneration; Middle Aged; Porphyrins; Randomized Controlled Trials as Topic; Ranibizumab; Vascular Endothelial Growth Factor A; Verteporfin; Visual Acuity

2014
Therapeutic modalities of exudative age-related macular degeneration.
    Medicinski arhiv, 2014, Volume: 68, Issue:3

    Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Bevacizumab; Combined Modality Therapy; Humans; Lenses, Intraocular; Macular Degeneration; Radiation, Ionizing; Ranibizumab; Receptors, Vascular Endothelial Growth Factor; Recombinant Fusion Proteins; Vascular Endothelial Growth Factor A

2014
Clinical characteristics and current treatment of age-related macular degeneration.
    Cold Spring Harbor perspectives in medicine, 2014, Oct-03, Volume: 5, Issue:1

    Topics: Aged; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Bevacizumab; Combined Modality Therapy; Drug Therapy, Combination; Humans; Light Coagulation; Macular Degeneration; Middle Aged; Photochemotherapy; Ranibizumab; Receptors, Vascular Endothelial Growth Factor; Recombinant Fusion Proteins; Risk Factors; Vascular Endothelial Growth Factor A

2014
Aptamers overview: selection, features and applications.
    Current topics in medicinal chemistry, 2015, Volume: 15, Issue:12

    Topics: Aptamers, Nucleotide; Biological Assay; Drug Delivery Systems; Drug Discovery; Food Technology; Humans; Macular Degeneration; Molecular Targeted Therapy; Reagent Kits, Diagnostic; SELEX Aptamer Technique; Small Molecule Libraries; Staining and Labeling

2015
Aptamer-targeted oligonucleotide theranostics: a smarter approach for brain delivery and the treatment of neurological diseases.
    Current topics in medicinal chemistry, 2015, Volume: 15, Issue:12

    Topics: Alzheimer Disease; Aptamers, Nucleotide; Aptamers, Peptide; Blood-Brain Barrier; Brain Neoplasms; Drug Delivery Systems; Humans; Macular Degeneration; Molecular Targeted Therapy; Multiple Sclerosis; Myasthenia Gravis; Parkinson Disease; SELEX Aptamer Technique; Stroke; Theranostic Nanomedicine

2015
Inhibitors of vascular endothelial growth factor (VEGF) in the management of neovascular age-related macular degeneration: a review of current practice.
    Clinical & experimental optometry, 2008, Volume: 91, Issue:5

    Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Bevacizumab; Choroidal Neovascularization; Clinical Trials as Topic; Humans; Macular Degeneration; Photochemotherapy; Ranibizumab; Vascular Endothelial Growth Factor A

2008
Anti-vascular endothelial growth factor pharmacotherapy for age-related macular degeneration: a report by the American Academy of Ophthalmology.
    Ophthalmology, 2008, Volume: 115, Issue:10

    Topics: Academies and Institutes; Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Bevacizumab; Choroidal Neovascularization; Drug Therapy; Humans; Macular Degeneration; Ranibizumab; Technology Assessment, Biomedical; Treatment Outcome; United States; Vascular Endothelial Growth Factor A

2008
Verteporfin combination regimens in the treatment of neovascular age-related macular degeneration.
    Retina (Philadelphia, Pa.), 2009, Volume: 29, Issue:2

    Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Bevacizumab; Choroidal Neovascularization; Drug Therapy, Combination; Humans; Macular Degeneration; Photochemotherapy; Photosensitizing Agents; Porphyrins; Ranibizumab; Vascular Endothelial Growth Factor A; Verteporfin

2009
[Age-related macular degeneration (AMD)].
    Therapeutische Umschau. Revue therapeutique, 2009, Volume: 66, Issue:3

    Topics: Adult; Age Factors; Aged; Antioxidants; Aptamers, Nucleotide; Diet; Fluorescein Angiography; Fundus Oculi; Genetic Predisposition to Disease; Humans; Macular Degeneration; Middle Aged; Photochemotherapy; Polymorphism, Genetic; Prevalence; Prospective Studies; Randomized Controlled Trials as Topic; Risk Factors; Smoking; Tomography, Optical Coherence; Vascular Endothelial Growth Factor A; Visual Acuity; Zinc

2009
Safety and efficacy of intravitreal anti-VEGF injections for age-related macular degeneration.
    Current opinion in ophthalmology, 2009, Volume: 20, Issue:3

    Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Bevacizumab; Humans; Injections; Macular Degeneration; Ranibizumab; Treatment Outcome; Vascular Endothelial Growth Factor A; Vitreous Body

2009
VEGF inhibitors for the treatment of neovascular age-related macular degeneration.
    Expert opinion on investigational drugs, 2009, Volume: 18, Issue:5

    Topics: Animals; Aptamers, Nucleotide; Humans; Macular Degeneration; Neovascularization, Pathologic; Treatment Outcome; Vascular Endothelial Growth Factor A

2009
Antivascular endothelial growth factor therapy for neovascular age-related macular degeneration.
    Current opinion in ophthalmology, 2009, Volume: 20, Issue:3

    Topics: Angiogenesis Inhibitors; Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Bevacizumab; Choroidal Neovascularization; Drug Approval; Humans; Macular Degeneration; Ranibizumab; United States; United States Food and Drug Administration; Vascular Endothelial Growth Factor A

2009
Treating age-related macular degeneration - interaction of VEGF-antagonists with their target.
    Mini reviews in medicinal chemistry, 2009, Volume: 9, Issue:9

    Topics: Age Factors; Amino Acid Sequence; Angiogenesis Inhibitors; Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Bevacizumab; Humans; Macular Degeneration; Molecular Sequence Data; Ranibizumab; Receptors, Vascular Endothelial Growth Factor; Recombinant Fusion Proteins; RNA, Small Interfering; Vascular Endothelial Growth Factors

2009
Aptamers: a new class of oligonucleotides in the drug discovery pipeline?
    Current opinion in pharmacology, 2009, Volume: 9, Issue:5

    Topics: Animals; Aptamers, Nucleotide; Drug Discovery; High-Throughput Screening Assays; Humans; Macular Degeneration; Nucleic Acid Conformation; SELEX Aptamer Technique; Small Molecule Libraries; Structure-Activity Relationship; Vascular Endothelial Growth Factor A

2009
Introduction: Understanding the role of angiogenesis and antiangiogenic agents in age-related macular degeneration.
    Ophthalmology, 2009, Volume: 116, Issue:10 Suppl

    Topics: Angiogenesis Inhibitors; Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Bevacizumab; Choroidal Neovascularization; Humans; Macular Degeneration; Ranibizumab; Vascular Endothelial Growth Factor A

2009
Systemic adverse drug reactions secondary to anti-VEGF intravitreal injection in patients with neovascular age-related macular degeneration.
    Current vascular pharmacology, 2011, Volume: 9, Issue:5

    Topics: Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Bevacizumab; Choroidal Neovascularization; Humans; Intravitreal Injections; Ligands; Macular Degeneration; Ranibizumab; Receptors, Vascular Endothelial Growth Factor; Treatment Outcome; Vascular Endothelial Growth Factor A; Visual Acuity

2011
A systematic review of the adverse events of intravitreal anti-vascular endothelial growth factor injections.
    Retina (Philadelphia, Pa.), 2011, Volume: 31, Issue:8

    Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Bevacizumab; Humans; Incidence; Intravitreal Injections; Macular Degeneration; Ranibizumab; Vascular Endothelial Growth Factor A

2011
Vascular endothelial growth factor inhibitors (anti-VEGF) in the management of diabetic macular oedema: a systematic review.
    The British journal of ophthalmology, 2012, Volume: 96, Issue:2

    Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Bevacizumab; Diabetic Retinopathy; Humans; Intravitreal Injections; Macular Degeneration; Macular Edema; Randomized Controlled Trials as Topic; Ranibizumab; Retreatment; Treatment Outcome; Vascular Endothelial Growth Factor A; Visual Acuity

2012
RNA aptamers: a review of recent trends and applications.
    Advances in biochemical engineering/biotechnology, 2013, Volume: 131

    Topics: Aptamers, Nucleotide; Clinical Trials as Topic; Cooperative Behavior; Humans; Inflammation; Ligands; Macular Degeneration; SELEX Aptamer Technique; Social Support; Vascular Endothelial Growth Factor A

2013
Biological, preclinical and clinical characteristics of inhibitors of vascular endothelial growth factors.
    Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde, 2012, Volume: 227 Suppl 1

    Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Bevacizumab; Diabetic Retinopathy; Humans; Macular Degeneration; Macular Edema; Ranibizumab; Receptors, Vascular Endothelial Growth Factor; Recombinant Fusion Proteins; Vascular Endothelial Growth Factor A

2012
Inhibitors of ocular neovascularization: promises and potential problems.
    JAMA, 2005, Mar-23, Volume: 293, Issue:12

    Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Diabetic Retinopathy; Humans; Injections; Macular Degeneration; Oligonucleotides; Ranibizumab; Vascular Endothelial Growth Factor A

2005
Pegaptanib sodium for the treatment of neovascular age-related macular degeneration.
    Expert opinion on investigational drugs, 2005, Volume: 14, Issue:5

    Topics: Aptamers, Nucleotide; Clinical Trials as Topic; Humans; Macular Degeneration; Retinal Neovascularization; Vascular Endothelial Growth Factor A; Vitreous Body

2005
Targeting angiogenesis, the underlying disorder in neovascular age-related macular degeneration.
    Canadian journal of ophthalmology. Journal canadien d'ophtalmologie, 2005, Volume: 40, Issue:3

    Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Bevacizumab; Humans; Macular Degeneration; Neovascularization, Pathologic; Treatment Outcome; Vascular Endothelial Growth Factor A

2005
Pegaptanib: the first antiangiogenic agent approved for neovascular macular degeneration.
    Expert opinion on pharmacotherapy, 2005, Volume: 6, Issue:8

    Topics: Angiogenesis Inhibitors; Animals; Aptamers, Nucleotide; Humans; Macular Degeneration; Neovascularization, Pathologic; Vascular Endothelial Growth Factor A

2005
Pegaptanib: in exudative age-related macular degeneration.
    Drugs, 2005, Volume: 65, Issue:11

    Topics: Animals; Aptamers, Nucleotide; Humans; Injections; Macular Degeneration; Oligonucleotides; Randomized Controlled Trials as Topic; Visual Acuity; Vitreous Body

2005
Regulatory aspects of drug approval for macular degeneration.
    Advanced drug delivery reviews, 2005, Dec-13, Volume: 57, Issue:14

    Topics: Aptamers, Nucleotide; Clinical Trials as Topic; Drug Approval; Drugs, Investigational; Humans; Macular Degeneration; Porphyrins; Treatment Outcome; United States; United States Food and Drug Administration; Vascular Endothelial Growth Factor A; Verteporfin

2005
neovascular age-related macular degeneration: Natural History and Treatment Outcomes.
    Retina (Philadelphia, Pa.), 2005, Volume: 25, Issue:8

    Topics: Aptamers, Nucleotide; Choroidal Neovascularization; Fluorescein Angiography; Humans; Laser Coagulation; Macular Degeneration; Photochemotherapy; Prognosis; Treatment Outcome; Visual Acuity

2005
Pegaptanib sodium for the treatment of neovascular age-related macular degeneration: a review.
    Clinical therapeutics, 2006, Volume: 28, Issue:1

    Topics: Animals; Aptamers, Nucleotide; Choroidal Neovascularization; Humans; Macular Degeneration; Treatment Outcome

2006
How you can help when older eyes fail.
    RN, 2006, Volume: 69, Issue:2

    Topics: Age Distribution; Aged; Aptamers, Nucleotide; Causality; Disease Progression; Humans; Laser Coagulation; Macular Degeneration; Middle Aged; Nurse's Role; Nursing Assessment; Patient Education as Topic; Photochemotherapy; Referral and Consultation; Risk Assessment; United States; Visual Acuity

2006
Pegaptanib for the treatment of age-related macular degeneration.
    Experimental eye research, 2006, Volume: 83, Issue:3

    Topics: Aptamers, Nucleotide; Drug Administration Schedule; Drug Costs; Humans; Macular Degeneration; Models, Animal; Randomized Controlled Trials as Topic; Vascular Endothelial Growth Factor A

2006
Promising new treatments for neovascular age-related macular degeneration.
    Expert opinion on investigational drugs, 2006, Volume: 15, Issue:7

    Topics: Aging; Angiogenesis Inhibitors; Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Bevacizumab; Capillary Permeability; Cholestanols; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Double-Blind Method; Drug Design; Drugs, Investigational; Eye Proteins; Humans; Injections; Lactates; Macular Degeneration; Models, Animal; Multicenter Studies as Topic; Neovascularization, Pathologic; Nerve Growth Factors; Pigment Epithelium of Eye; Protein Isoforms; Randomized Controlled Trials as Topic; RNA Interference; RNA, Small Interfering; Serpins; Stilbenes; Treatment Outcome; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-2; Vitreous Body

2006
Pegaptanib (Macugen): treating neovascular age-related macular degeneration and current role in clinical practice.
    Ophthalmology clinics of North America, 2006, Volume: 19, Issue:3

    Topics: Aptamers, Nucleotide; Humans; Macular Degeneration; Retinal Neovascularization; Treatment Outcome; Vascular Endothelial Growth Factor A

2006
Expanding treatment options in age-related macular degeneration.
    International ophthalmology clinics, 2006,Fall, Volume: 46, Issue:4

    Topics: Aptamers, Nucleotide; Drug Therapy, Combination; Humans; Macular Degeneration; Photochemotherapy; Photosensitizing Agents; Treatment Outcome; Vascular Endothelial Growth Factor A

2006
Macugen (pegaptanib sodium), a novel ocular therapeutic that targets vascular endothelial growth factor (VEGF).
    International ophthalmology clinics, 2006,Fall, Volume: 46, Issue:4

    Topics: Aptamers, Nucleotide; Humans; Macular Degeneration; Retinal Neovascularization; Treatment Outcome; Vascular Endothelial Growth Factor A

2006
Anti-VEGF aptamer (pegaptanib) therapy for ocular vascular diseases.
    Annals of the New York Academy of Sciences, 2006, Volume: 1082

    Topics: Aptamers, Nucleotide; Clinical Trials as Topic; Diabetes Complications; Humans; Macular Degeneration; Macular Edema; Retinal Degeneration; Treatment Outcome; Vascular Endothelial Growth Factor A

2006
Progressive visual loss in subfoveal exudation in age-related macular degeneration: a meta-analysis using Lineweaver-Burke plots.
    American journal of ophthalmology, 2007, Volume: 143, Issue:1

    Topics: Angiogenesis Inhibitors; Aptamers, Nucleotide; Blindness; Choroidal Neovascularization; Disease Progression; Exudates and Transudates; Humans; Macula Lutea; Macular Degeneration; Photochemotherapy; Pregnadienediols; Randomized Controlled Trials as Topic; Retrospective Studies; Vascular Endothelial Growth Factor A; Visual Acuity

2007
Antiangiogenic therapy in neovascular age-related macular degeneration.
    International ophthalmology clinics, 2007,Winter, Volume: 47, Issue:1

    Topics: Angiogenesis Inhibitors; Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Choroidal Neovascularization; Humans; Macular Degeneration; Photochemotherapy; Photosensitizing Agents; Ranibizumab; Treatment Outcome; Vascular Endothelial Growth Factor A

2007
Verteporfin photodynamic therapy and anti-angiogenic drugs: potential for combination therapy in exudative age-related macular degeneration.
    Current medical research and opinion, 2007, Volume: 23, Issue:3

    Topics: Age Factors; Aged; Angiogenesis Inhibitors; Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Choroidal Neovascularization; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Female; Haplorhini; Humans; Macular Degeneration; Male; Middle Aged; Photochemotherapy; Porphyrins; Prognosis; Ranibizumab; Risk Assessment; Treatment Outcome; Verteporfin; Visual Acuity

2007
[Age-related macular degeneration (AMD): etiopathogenesis and therapeutic strategies].
    Postepy higieny i medycyny doswiadczalnej (Online), 2007, Volume: 61

    Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antioxidants; Aptamers, Nucleotide; Bevacizumab; Humans; Lipofuscin; Macular Degeneration; Neovascularization, Pathologic; Photochemotherapy; Pregnadienediols; Ranibizumab; Retinal Drusen; Triamcinolone Acetonide

2007
[Pegaptanib sodium in treatment of wet AMD].
    Klinika oczna, 2006, Volume: 108, Issue:10-12

    Topics: Aptamers, Nucleotide; Humans; Macular Degeneration; Practice Guidelines as Topic; Randomized Controlled Trials as Topic; Retinal Neovascularization; Vascular Endothelial Growth Factor A

2006
Pegaptanib and ranibizumab for neovascular age-related macular degeneration: a systematic review.
    The British journal of ophthalmology, 2007, Volume: 91, Issue:9

    Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Choroidal Neovascularization; Disease Progression; Humans; Macular Degeneration; Randomized Controlled Trials as Topic; Ranibizumab; Treatment Outcome; Vascular Endothelial Growth Factor A; Visual Acuity

2007
[Molecular pathogenesis of ocular vascular disease--anti-angiogenesis as a therapeutic concept].
    Deutsche medizinische Wochenschrift (1946), 2007, Jun-08, Volume: 132, Issue:23

    Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Bevacizumab; Diabetic Angiopathies; Diabetic Retinopathy; Humans; Infant, Newborn; Macular Degeneration; Neovascularization, Pathologic; Ranibizumab; Retinal Diseases; Retinopathy of Prematurity; Vascular Diseases

2007
[VEGF in age-related macular degeneration. Part II. VEGF inhibitors use in age-related macular degeneration treatment].
    Klinika oczna, 2007, Volume: 109, Issue:1-3

    Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Humans; Macular Degeneration; Randomized Controlled Trials as Topic; Ranibizumab; Retina; Treatment Outcome; Vascular Endothelial Growth Factor A

2007
Targeting vascular endothelial growth factor: a promising strategy for treating age-related macular degeneration.
    Drugs & aging, 2007, Volume: 24, Issue:8

    Topics: Aging; Angiogenesis Inhibitors; Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Bevacizumab; Choroidal Neovascularization; Drug Delivery Systems; Humans; Injections; Macular Degeneration; Ranibizumab; Vascular Endothelial Growth Factor A; Visual Acuity; Vitreous Body

2007
Pegaptanib in the treatment of wet, age-related macular degeneration.
    International journal of nanomedicine, 2006, Volume: 1, Issue:3

    Topics: Aptamers, Nucleotide; Choroidal Neovascularization; Clinical Trials as Topic; Humans; Macular Degeneration; Vascular Endothelial Growth Factor A

2006
A view on new drugs for macular degeneration.
    Drug and therapeutics bulletin, 2007, Volume: 45, Issue:7

    Topics: Aged; Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Bevacizumab; Drugs, Investigational; Humans; Macular Degeneration; Ranibizumab

2007
Pharmacotherapy for the treatment of choroidal neovascularization due to age-related macular degeneration.
    Annual review of pharmacology and toxicology, 2008, Volume: 48

    Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Bevacizumab; Choroidal Neovascularization; Humans; Laser Coagulation; Macular Degeneration; Porphyrins; Prevalence; Ranibizumab; Verteporfin

2008
Pegaptanib sodium for the treatment of age-related macular degeneration.
    Expert opinion on pharmacotherapy, 2008, Volume: 9, Issue:3

    Topics: Aged; Angiogenesis Inhibitors; Aptamers, Nucleotide; Choroidal Neovascularization; Humans; Macular Degeneration; Protein Isoforms; Vascular Endothelial Growth Factor A

2008
[Monitoring of AMD patients on anti-vascular endothelial growth factor (VEGF) treatment. Practical notes on functional and anatomical examination parameters from drug approval studies, specialist information and case series].
    Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft, 2008, Volume: 105, Issue:2

    Topics: Aged; Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Bevacizumab; Blindness; Choroidal Neovascularization; Clinical Trials, Phase III as Topic; Fluorescein Angiography; Follow-Up Studies; Humans; Injections; Macular Degeneration; Meta-Analysis as Topic; Monitoring, Physiologic; Multicenter Studies as Topic; Photochemotherapy; Photosensitizing Agents; Porphyrins; Randomized Controlled Trials as Topic; Ranibizumab; Retrospective Studies; Time Factors; Tomography, Optical Coherence; Treatment Outcome; Vascular Endothelial Growth Factor A; Verteporfin; Vision Tests; Visual Acuity; Vitreous Body

2008
[Intravitreal injection. Monitoring to avoid postoperative complications].
    Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft, 2008, Volume: 105, Issue:2

    Topics: Adult; Aged; Angiogenesis Inhibitors; Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Bevacizumab; Cataract; Clinical Trials, Phase III as Topic; Endophthalmitis; Eye Hemorrhage; Female; Fetus; Hallucinations; Humans; Injections; Intraocular Pressure; Macular Degeneration; Mice; Paracentesis; Postoperative Complications; Pregnancy; Rabbits; Randomized Controlled Trials as Topic; Ranibizumab; Retinal Detachment; Uveitis; Vascular Endothelial Growth Factor A; Vitreous Body

2008
[Age-related macular degeneration].
    La Revue de medecine interne, 2008, Volume: 29, Issue:3

    Topics: Age Factors; Aged; Aged, 80 and over; Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Dietary Supplements; Fluorescein Angiography; Humans; Laser Coagulation; Macular Degeneration; Middle Aged; Photochemotherapy; Photosensitizing Agents; Porphyrins; Ranibizumab; Tomography, Optical Coherence; Vascular Endothelial Growth Factor A; Verteporfin

2008
[New drugs; pegaptanib and ranibizumab].
    Nederlands tijdschrift voor geneeskunde, 2008, Jan-12, Volume: 152, Issue:2

    Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Disease Progression; Humans; Macular Degeneration; Ranibizumab; Treatment Outcome; Vascular Endothelial Growth Factor A; Visual Acuity

2008
The evolving role of vascular endothelial growth factor inhibitors in the treatment of neovascular age-related macular degeneration.
    Eye (London, England), 2008, Volume: 22, Issue:6

    Topics: Aged; Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Bevacizumab; Clinical Trials, Phase III as Topic; Corneal Neovascularization; Dose-Response Relationship, Drug; Female; Humans; Macular Degeneration; Male; Practice Guidelines as Topic; Ranibizumab; Tomography, Optical Coherence; Vascular Endothelial Growth Factor A

2008
Antiangiogenic therapy with anti-vascular endothelial growth factor modalities for neovascular age-related macular degeneration.
    The Cochrane database of systematic reviews, 2008, Apr-16, Issue:2

    Topics: Aged; Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Choroidal Neovascularization; Humans; Macular Degeneration; Middle Aged; Porphyrins; Randomized Controlled Trials as Topic; Ranibizumab; Vascular Endothelial Growth Factor A; Verteporfin

2008
Ranibizumab and pegaptanib for the treatment of age-related macular degeneration: a systematic review and economic evaluation.
    Health technology assessment (Winchester, England), 2008, Volume: 12, Issue:16

    Topics: Age Factors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Choroidal Neovascularization; Contrast Sensitivity; Cost-Benefit Analysis; Drug Costs; Humans; Macular Degeneration; Randomized Controlled Trials as Topic; Ranibizumab; Visual Acuity

2008

Trials

21 trial(s) available for almagate and Age-Related Macular Degeneration

ArticleYear
The Additional Value of an E-Mail to Inform Healthcare Professionals of a Drug Safety Issue: A Randomized Controlled Trial in the Netherlands.
    Drug safety, 2013, Volume: 36, Issue:9

    Topics: Adult; Adverse Drug Reaction Reporting Systems; Aptamers, Nucleotide; Attitude of Health Personnel; Communication; Electronic Mail; Female; Humans; Macular Degeneration; Male; Middle Aged; Netherlands; Ophthalmology; Physicians

2013
Pegaptanib sodium for neovascular age-related macular degeneration: third-year safety results of the VEGF Inhibition Study in Ocular Neovascularisation (VISION) trial.
    The British journal of ophthalmology, 2008, Volume: 92, Issue:12

    Topics: Aged; Aptamers, Nucleotide; Choroidal Neovascularization; Female; Fluorescein Angiography; Humans; Intraocular Pressure; Macular Degeneration; Male; Tonometry, Ocular; Treatment Outcome; Vascular Endothelial Growth Factor A

2008
[Pegaptanib sodium one-year treatment study for neovascular age-related macular degeneration].
    Nippon Ganka Gakkai zasshi, 2008, Volume: 112, Issue:7

    Topics: Aged; Aptamers, Nucleotide; Choroidal Neovascularization; Double-Blind Method; Female; Humans; Injections; Macular Degeneration; Male; Vascular Endothelial Growth Factor A; Visual Acuity; Vitreous Body

2008
[Treatment of vascularised serous pigment epithelium detachment in AMD - observations after changing the intravitreal agent due to lack of response].
    Klinische Monatsblatter fur Augenheilkunde, 2008, Volume: 225, Issue:10

    Topics: Aged; Aptamers, Nucleotide; Dose-Response Relationship, Drug; Female; Humans; Macular Degeneration; Male; Retinal Detachment; Treatment Outcome; Vascular Endothelial Growth Factor A

2008
Pegaptanib sodium as maintenance therapy in neovascular age-related macular degeneration: the LEVEL study.
    The British journal of ophthalmology, 2010, Volume: 94, Issue:12

    Topics: Aged; Angiogenesis Inhibitors; Aptamers, Nucleotide; Cornea; Female; Humans; Macular Degeneration; Male; Middle Aged; Prospective Studies; Tomography, Optical Coherence; Treatment Outcome; Vascular Endothelial Growth Factor A; Visual Acuity; Wet Macular Degeneration

2010
Effects of retinal morphology on contrast sensitivity and reading ability in neovascular age-related macular degeneration.
    Investigative ophthalmology & visual science, 2010, Volume: 51, Issue:11

    Topics: Aged; Aged, 80 and over; Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Bevacizumab; Choroidal Neovascularization; Contrast Sensitivity; Cross-Sectional Studies; Double-Blind Method; Female; Humans; Macular Degeneration; Male; Middle Aged; Photochemotherapy; Reading; Retina; Subretinal Fluid; Tomography, Optical Coherence; Vascular Endothelial Growth Factor A; Visual Acuity

2010
[Long-term efficacy and safety profile of pegaptanib sodium for age-related macular degeneration with choroidal neovascularization--evaluation of extended phase II clinical trial].
    Nippon Ganka Gakkai zasshi, 2011, Volume: 115, Issue:2

    Topics: Aged; Aged, 80 and over; Aptamers, Nucleotide; Choroidal Neovascularization; Female; Humans; Macular Degeneration; Male; Vascular Endothelial Growth Factor A; Visual Acuity

2011
Population pharmacokinetics of pegaptanib in patients with neovascular, age-related macular degeneration.
    Journal of clinical pharmacology, 2012, Volume: 52, Issue:8

    Topics: Aged; Aptamers, Nucleotide; Area Under Curve; Cohort Studies; Female; Humans; Kidney Function Tests; Macular Degeneration; Male; Renal Insufficiency; Vascular Endothelial Growth Factor A; Visual Acuity

2012
Assessment of differential pharmacodynamic effects using optical coherence tomography in neovascular age-related macular degeneration.
    Investigative ophthalmology & visual science, 2012, Volume: 53, Issue:3

    Topics: Aged; Aged, 80 and over; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Bevacizumab; Choroidal Neovascularization; Dose-Response Relationship, Drug; Double-Blind Method; Female; Follow-Up Studies; Humans; Intravitreal Injections; Macular Degeneration; Male; Middle Aged; Retrospective Studies; Tomography, Optical Coherence; Treatment Outcome; Vascular Endothelial Growth Factor A

2012
Retinal pigment epithelium tears in age-related macular degeneration treated with antiangiogenic drugs: a controlled study with long follow-up.
    Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde, 2012, Volume: 228, Issue:2

    Topics: Aged; Aged, 80 and over; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Bevacizumab; Case-Control Studies; Female; Fluorescein Angiography; Follow-Up Studies; Humans; Intravitreal Injections; Macular Degeneration; Male; Middle Aged; Ranibizumab; Retinal Perforations; Retinal Pigment Epithelium; Retrospective Studies; Tomography, Optical Coherence; Vascular Endothelial Growth Factor A; Visual Acuity

2012
A retrospective, pooled data analysis of the safety of pegaptanib sodium in the treatment of age-related macular degeneration in subjects with or without diabetes mellitus.
    BMC ophthalmology, 2012, Aug-08, Volume: 12

    Topics: Aptamers, Nucleotide; Choroidal Neovascularization; Cross-Over Studies; Diabetes Mellitus; Dose-Response Relationship, Drug; Follow-Up Studies; Humans; Macular Degeneration; Retrospective Studies; Treatment Outcome; Vascular Endothelial Growth Factor A

2012
Treating early choroidal neovascularisation with pegaptanib sodium in patients with neovascular age-related macular degeneration: findings of the PERSPECTIVES study.
    The British journal of ophthalmology, 2012, Volume: 96, Issue:10

    Topics: Angiogenesis Inhibitors; Aptamers, Nucleotide; Choroidal Neovascularization; Early Diagnosis; Humans; Macular Degeneration; Middle Aged

2012
Pegaptanib for neovascular age-related macular degeneration.
    The New England journal of medicine, 2004, Dec-30, Volume: 351, Issue:27

    Topics: Aged; Aged, 80 and over; Aptamers, Nucleotide; Choroidal Neovascularization; Double-Blind Method; Female; Humans; Injections; Macular Degeneration; Male; Middle Aged; Oligonucleotides; Photochemotherapy; Prospective Studies; Radiography; Vascular Endothelial Growth Factor A; Visual Acuity; Vitreous Body

2004
[Treatment of neovascular age-related macular degeneration with intravitreal vascular endothelial growth factor inhibitor--secondary publication].
    Ugeskrift for laeger, 2005, Aug-29, Volume: 167, Issue:35

    Topics: Aged; Aged, 80 and over; Angiogenesis Inhibitors; Aptamers, Nucleotide; Choroidal Neovascularization; Female; Fluorescein Angiography; Humans; Injections; Macular Degeneration; Male; Middle Aged; Oligonucleotides; Photochemotherapy; Treatment Outcome; Vascular Endothelial Growth Factors; Visual Acuity; Vitreous Body

2005
Pegaptanib sodium for neovascular age-related macular degeneration: two-year safety results of the two prospective, multicenter, controlled clinical trials.
    Ophthalmology, 2006, Volume: 113, Issue:6

    Topics: Aged; Aged, 80 and over; Aptamers, Nucleotide; Choroidal Neovascularization; Double-Blind Method; Female; Fluorescein Angiography; Humans; Injections; Intraocular Pressure; Macular Degeneration; Male; Middle Aged; Prospective Studies; Treatment Outcome; Vascular Endothelial Growth Factor A; Visual Acuity; Vitreous Body

2006
Year 2 efficacy results of 2 randomized controlled clinical trials of pegaptanib for neovascular age-related macular degeneration.
    Ophthalmology, 2006, Volume: 113, Issue:9

    Topics: Aged; Aged, 80 and over; Aptamers, Nucleotide; Choroidal Neovascularization; Double-Blind Method; Female; Fluorescein Angiography; Humans; Indocyanine Green; Injections; Macular Degeneration; Male; Middle Aged; Prospective Studies; Treatment Outcome; Vascular Endothelial Growth Factor A; Visual Acuity; Vitreous Body

2006
A randomized trial of Pegaptanib sodium for age-related macular degeneration used an innovative design to explore disease-modifying effects.
    Journal of clinical epidemiology, 2007, Volume: 60, Issue:5

    Topics: Aptamers, Nucleotide; Choroidal Neovascularization; Drug Administration Schedule; Humans; Injections; Macular Degeneration; Middle Aged; Prospective Studies; Research Design; Treatment Outcome; Vascular Endothelial Growth Factor A; Visual Acuity; Vitreous Body

2007
Pegaptanib 1-year systemic safety results from a safety-pharmacokinetic trial in patients with neovascular age-related macular degeneration.
    Ophthalmology, 2007, Volume: 114, Issue:9

    Topics: Aged; Aged, 80 and over; Angiogenesis Inhibitors; Aptamers, Nucleotide; Blood Pressure; Choroidal Neovascularization; Double-Blind Method; Female; Half-Life; Humans; Immunoglobulin G; Immunoglobulin M; Injections; Intraocular Pressure; Macular Degeneration; Male; Middle Aged; Prospective Studies; Proteinuria; Vascular Endothelial Growth Factor A; Vitreous Body

2007
Quality of life in patients with age-related macular degeneration: results from the VISION study.
    Eye (London, England), 2008, Volume: 22, Issue:6

    Topics: Aged; Aged, 80 and over; Aptamers, Nucleotide; Choroidal Neovascularization; Female; Humans; Macular Degeneration; Male; Middle Aged; Quality of Life; Sickness Impact Profile; Visual Acuity

2008
Combined Pegaptanib sodium (Macugen) and photodynamic therapy in predominantly classic juxtafoveal choroidal neovascularisation in age related macular degeneration.
    The British journal of ophthalmology, 2008, Volume: 92, Issue:1

    Topics: Aged; Angiogenesis Inhibitors; Aptamers, Nucleotide; Choroidal Neovascularization; Combined Modality Therapy; Female; Humans; Macular Degeneration; Male; Middle Aged; Photochemotherapy; Prospective Studies; Treatment Outcome; Vascular Endothelial Growth Factor A; Visual Acuity

2008
[Pegaptanib sodium in treatment of choroidal neovascularization secondary to age-related macular degeneration. One year results].
    Klinika oczna, 2007, Volume: 109, Issue:10-12

    Topics: Aptamers, Nucleotide; Choroidal Neovascularization; Female; Humans; Macular Degeneration; Male; Prospective Studies; Treatment Outcome

2007

Other Studies

110 other study(ies) available for almagate and Age-Related Macular Degeneration

ArticleYear
The impact of data errors on the outcome of randomized clinical trials.
    Clinical trials (London, England), 2017, Volume: 14, Issue:5

    Topics: Antineoplastic Agents, Immunological; Aptamers, Nucleotide; Cetuximab; Colorectal Neoplasms; Data Accuracy; Data Interpretation, Statistical; Endpoint Determination; Humans; Macular Degeneration; Observer Variation; Randomized Controlled Trials as Topic; Treatment Outcome

2017
Pegaptanib: choroidal neovascularization in patients with age-related macular degeneration and previous arterial thromboembolic events.
    European journal of ophthalmology, 2018, Volume: 28, Issue:1

    Topics: Aged; Aptamers, Nucleotide; Choroidal Neovascularization; Female; Fluorescein Angiography; Follow-Up Studies; Fundus Oculi; Humans; Intravitreal Injections; Macular Degeneration; Male; Retrospective Studies; Thromboembolism; Tomography, Optical Coherence; Treatment Outcome; Vascular Endothelial Growth Factor A; Visual Acuity; Vitreous Body

2018
The use of intravitreal anti-vascular endothelial growth factor injection and its complications in Chiang Mai University Hospital.
    Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 2013, Volume: 96, Issue:11

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Bevacizumab; Child; Child, Preschool; Diabetic Retinopathy; Female; Hospitals, University; Humans; Infant; Intravitreal Injections; Macular Degeneration; Male; Middle Aged; Ranibizumab; Retinal Vein Occlusion; Retrospective Studies; Thailand; Vascular Endothelial Growth Factor A; Young Adult

2013
Comparative safety profiles of intravitreal bevacizumab, ranibizumab and pegaptanib: the analysis of the WHO database of adverse drug reactions.
    European journal of clinical pharmacology, 2014, Volume: 70, Issue:12

    Topics: Adverse Drug Reaction Reporting Systems; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Bevacizumab; Female; Humans; Intravitreal Injections; Macular Degeneration; Male; Ranibizumab; World Health Organization

2014
Effect of switching therapy to pegaptanib in eyes with the persistent cases of exudative age-related macular degeneration.
    Medicine, 2014, Volume: 93, Issue:18

    Topics: Aged; Aged, 80 and over; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Combined Modality Therapy; Drug Substitution; Exudates and Transudates; Female; Humans; Intravitreal Injections; Macular Degeneration; Macular Edema; Male; Middle Aged; Photochemotherapy; Prospective Studies; Radiography; Ranibizumab; Retina; Retinal Detachment; Tomography, Optical Coherence; Treatment Failure; Visual Acuity

2014
Comparative study of photodynamic therapy monotherapy versus triple management in age-related macular degeneration.
    Turkish journal of medical sciences, 2014, Volume: 44, Issue:5

    Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Bevacizumab; Combined Modality Therapy; Female; Glucocorticoids; Humans; Intravitreal Injections; Macular Degeneration; Male; Photochemotherapy; Treatment Outcome; Triamcinolone; Vascular Endothelial Growth Factor A; Visual Acuity

2014
Influence of anti-VEGF about cardiovascular biomarkers in age related macular degeneration.
    The journal of nutrition, health & aging, 2015, Volume: 19, Issue:2

    Topics: Aged; Aged, 80 and over; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Atherosclerosis; Biomarkers; C-Reactive Protein; Cardiovascular Diseases; Female; Fibrinogen; Homocysteine; Humans; Lipids; Macular Degeneration; Male; Middle Aged; Ranibizumab; Risk Factors; Vascular Endothelial Growth Factor A; Wet Macular Degeneration

2015
Vascular Endothelial Growth Factor (VEGF) Concentration Is Underestimated by Enzyme-Linked Immunosorbent Assay in the Presence of Anti-VEGF Drugs.
    Investigative ophthalmology & visual science, 2016, Volume: 57, Issue:2

    Topics: Angiogenesis Inhibitors; Aptamers, Nucleotide; Bevacizumab; Chemokine CCL2; Enzyme-Linked Immunosorbent Assay; Half-Life; Humans; Intravitreal Injections; Macular Degeneration; Ranibizumab; Reagent Kits, Diagnostic; Receptors, Vascular Endothelial Growth Factor; Recombinant Fusion Proteins; Reproducibility of Results; Vascular Endothelial Growth Factor A; Vitreous Body

2016
Association of neovascular age-related macular degeneration with month and season of birth in Italy.
    Aging, 2016, 12-19, Volume: 9, Issue:1

    Topics: Aged; Aged, 80 and over; Angiogenesis Inhibitors; Aptamers, Nucleotide; Bevacizumab; Female; Humans; Incidence; Italy; Macular Degeneration; Male; Neovascularization, Pathologic; Ranibizumab; Receptors, Vascular Endothelial Growth Factor; Recombinant Fusion Proteins; Registries; Seasons; Treatment Outcome; Vascular Endothelial Growth Factor A

2016
[Clinical experience in the treatment of neovascular age-related macular degeneration with pegaptanib].
    Klinische Monatsblatter fur Augenheilkunde, 2008, Volume: 225, Issue:6

    Topics: Aged; Aged, 80 and over; Aptamers, Nucleotide; Choroidal Neovascularization; Drug Administration Schedule; Female; Fluorescein Angiography; Humans; Injections; Intraocular Pressure; Macular Degeneration; Male; Middle Aged; Retreatment; Vascular Endothelial Growth Factor A; Visual Acuity; Vitreous Body

2008
[Treatment of neovascular age-related macular degeneration: an unresolved matter].
    Archivos de la Sociedad Espanola de Oftalmologia, 2008, Volume: 83, Issue:7

    Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Bevacizumab; Drug Approval; Drug Costs; Europe; Humans; Macular Degeneration; National Health Programs; New Zealand; Porphyrins; Ranibizumab; Spain; State Medicine; United States; Verteporfin

2008
Predictors of anti-VEGF-associated retinal pigment epithelial tear using FA and OCT analysis.
    Retina (Philadelphia, Pa.), 2008, Volume: 28, Issue:9

    Topics: Aged; Aged, 80 and over; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Bevacizumab; Choroidal Neovascularization; Female; Fluorescein Angiography; Humans; Macular Degeneration; Male; Predictive Value of Tests; Ranibizumab; Retinal Detachment; Retinal Perforations; Retinal Pigment Epithelium; Retinal Vessels; Retrospective Studies; Risk Assessment; Tomography, Optical Coherence; Vascular Endothelial Growth Factor A

2008
Pegaptanib sodium for occult choroidal neovascularization in neovascular age-related macular degeneration: a prospective case series.
    Eye (London, England), 2009, Volume: 23, Issue:5

    Topics: Aged; Aged, 80 and over; Aptamers, Nucleotide; Choroidal Neovascularization; Compassionate Use Trials; Female; Fluorescein Angiography; Humans; Macular Degeneration; Male; Middle Aged; Outcome Assessment, Health Care; Prospective Studies; Vascular Endothelial Growth Factor A; Visual Acuity

2009
Cost-effectiveness sequential modeling of ranibizumab versus usual care in age-related macular degeneration.
    Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2008, Volume: 246, Issue:11

    Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Blindness; Computer Simulation; Cost-Benefit Analysis; Decision Trees; Drug Therapy, Combination; Humans; Laser Therapy; Macular Degeneration; Models, Economic; Photosensitizing Agents; Population Surveillance; Porphyrins; Ranibizumab; Treatment Outcome; Verteporfin; Visual Acuity

2008
[Evolving intravitreous injection technique].
    Journal francais d'ophtalmologie, 2008, Volume: 31, Issue:6 Pt 1

    Topics: Adrenal Cortex Hormones; Antibiotic Prophylaxis; Aptamers, Nucleotide; Comorbidity; Contraindications; Drug Hypersensitivity; Eye Infections; Humans; Informed Consent; Injections; Macular Degeneration; Monitoring, Physiologic; Mydriatics; Practice Guidelines as Topic; Pupil; Retinal Artery Occlusion; Tonometry, Ocular; Unnecessary Procedures; Vitreous Body; Vitreous Hemorrhage

2008
Are intravitreal bevacizumab and ranibizumab effective in a rat model of choroidal neovascularization?
    Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2009, Volume: 247, Issue:2

    Topics: Angiogenesis Inhibitors; Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Bevacizumab; Choroidal Neovascularization; Disease Models, Animal; Dose-Response Relationship, Drug; Fluorescein Angiography; Injections; Light Coagulation; Macular Degeneration; Ranibizumab; Rats; Rats, Inbred BN; Vascular Endothelial Growth Factor A; Vitreous Body

2009
[Intravitreous injection: retrospective study on 2028 injections and their side effects].
    Journal francais d'ophtalmologie, 2008, Volume: 31, Issue:7

    Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Cataract; Diabetic Retinopathy; Endophthalmitis; Epiretinal Membrane; Humans; Injections; Macular Degeneration; Macular Edema; Ocular Hypertension; Ranibizumab; Retinal Detachment; Retinal Perforations; Retinal Vein Occlusion; Retrospective Studies; Risk Assessment; Triamcinolone Acetonide; Vitreous Body; Vitreous Hemorrhage

2008
Safety monitoring with ocular anti-vascular endothelial growth factor therapies.
    The British journal of ophthalmology, 2008, Volume: 92, Issue:12

    Topics: Aptamers, Nucleotide; Diabetic Retinopathy; Humans; Macular Degeneration; Macular Edema; Vascular Endothelial Growth Factors

2008
Applying the CONSORT and STROBE statements to evaluate the reporting quality of neovascular age-related macular degeneration studies.
    Ophthalmology, 2009, Volume: 116, Issue:2

    Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Bevacizumab; Choroidal Neovascularization; Guidelines as Topic; Humans; Macular Degeneration; Ophthalmology; Periodicals as Topic; Photochemotherapy; Photosensitizing Agents; Porphyrins; Publishing; Quality Control; Randomized Controlled Trials as Topic; Ranibizumab; Verteporfin

2009
Cost-effectiveness of ranibizumab compared with photodynamic treatment of neovascular age-related macular degeneration.
    Clinical therapeutics, 2008, Volume: 30, Issue:12

    Topics: Aged, 80 and over; Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Choroidal Neovascularization; Cost-Benefit Analysis; Humans; Injections; Insurance, Health, Reimbursement; Macular Degeneration; Markov Chains; Middle Aged; Photochemotherapy; Quality of Life; Ranibizumab; Reproducibility of Results; Spain; Visual Acuity

2008
Serous pigment epithelial detachment in age-related macular degeneration: comparison of different treatments.
    Eye (London, England), 2009, Volume: 23, Issue:12

    Topics: Aged; Aged, 80 and over; Angiogenesis Inhibitors; Anti-Inflammatory Agents; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Bevacizumab; Female; Fluorescein Angiography; Follow-Up Studies; Fovea Centralis; Humans; Immunologic Factors; Intravitreal Injections; Macular Degeneration; Male; Middle Aged; Photochemotherapy; Pigment Epithelium of Eye; Ranibizumab; Retinal Detachment; Retrospective Studies; Tomography, Optical Coherence; Triamcinolone Acetonide; Visual Acuity

2009
New paradigms in the treatment of wet AMD: the impact of anti-VEGF therapy.
    Eye (London, England), 2009, Volume: 23 Suppl 1

    Topics: Ambulatory Care; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Critical Pathways; Early Diagnosis; England; Humans; Macular Degeneration; Physical Examination; Practice Guidelines as Topic; Ranibizumab; Referral and Consultation; Vascular Endothelial Growth Factor A

2009
Endophthalmitis after anti-VEGF injections.
    Ophthalmology, 2009, Volume: 116, Issue:6

    Topics: Angiogenesis Inhibitors; Anti-Bacterial Agents; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Bevacizumab; Cohort Studies; Drug Therapy, Combination; Endophthalmitis; Humans; Injections; Macular Degeneration; Ranibizumab; Risk Factors; Vascular Endothelial Growth Factor A; Vitreous Body

2009
Cost-effectiveness of ranibizumab compared with pegaptanib in neovascular age-related macular degeneration.
    Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2010, Volume: 248, Issue:4

    Topics: Aged; Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Choroidal Neovascularization; Cost-Benefit Analysis; Costs and Cost Analysis; Health Care Costs; Health Services Research; Humans; Macular Degeneration; Markov Chains; Quality-Adjusted Life Years; Ranibizumab; Spain; Visual Acuity

2010
[Application of aptamers to medicine: pharmacological profile and results of clinical trials on pegaptanib sodium (Macugen) for age-related macular degeneration].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 2009, Volume: 134, Issue:2

    Topics: Animals; Aptamers, Nucleotide; Humans; Macular Degeneration; Mice; Receptors, Vascular Endothelial Growth Factor; Vascular Endothelial Growth Factor A

2009
Safety implications of vascular endothelial growth factor blockade for subjects receiving intravitreal anti-vascular endothelial growth factor therapies.
    American journal of ophthalmology, 2009, Volume: 148, Issue:5

    Topics: Adverse Drug Reaction Reporting Systems; Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Bevacizumab; Choroidal Neovascularization; Databases, Factual; Drug Administration Routes; Humans; Macular Degeneration; Medical Records Systems, Computerized; Meta-Analysis as Topic; Product Surveillance, Postmarketing; Ranibizumab; Receptors, Vascular Endothelial Growth Factor; Recombinant Fusion Proteins; Registries; Treatment Outcome; Vascular Endothelial Growth Factor A

2009
Intravitreal pegaptanib sodium for choroidal neovascularisation secondary to age-related macular degeneration: Pan-European experience.
    Eye (London, England), 2010, Volume: 24, Issue:5

    Topics: Aptamers, Nucleotide; Choroidal Neovascularization; Cohort Studies; Humans; Intravitreal Injections; Macular Degeneration; Retrospective Studies; Vascular Endothelial Growth Factors; Visual Acuity

2010
[Clinical experience with pegaptanib in the treatment of age-related macular degeneration (AMD)].
    Klinische Monatsblatter fur Augenheilkunde, 2010, Volume: 227, Issue:1

    Topics: Aged; Aged, 80 and over; Aptamers, Nucleotide; Female; Fluorescein Angiography; Humans; Injections; Intraocular Pressure; Macular Degeneration; Male; Retinal Neovascularization; Vascular Endothelial Growth Factor A; Visual Acuity; Vitreous Body

2010
A cost-effectiveness analysis of three treatments for age-related macular degeneration.
    Retina (Philadelphia, Pa.), 2010, Volume: 30, Issue:2

    Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Choroidal Neovascularization; Cost-Benefit Analysis; Drug Costs; Health Care Costs; Humans; Injections; Macular Degeneration; Models, Economic; Photochemotherapy; Photosensitizing Agents; Porphyrins; Quality of Life; Quality-Adjusted Life Years; Ranibizumab; Treatment Outcome; Vascular Endothelial Growth Factor A; Verteporfin; Visual Acuity; Vitreous Body

2010
Re: Verteporfin combination regimens in the treatment of neovascular age-related macular degeneration.
    Retina (Philadelphia, Pa.), 2010, Volume: 30, Issue:2

    Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Bevacizumab; Choroidal Neovascularization; Drug Therapy, Combination; Humans; Macular Degeneration; Photochemotherapy; Photosensitizing Agents; Porphyrins; Ranibizumab; Vascular Endothelial Growth Factor A; Verteporfin

2010
Newly diagnosed exudative age-related macular degeneration treated with pegaptanib sodium monotherapy in US community-based practices: medical chart review study.
    BMC ophthalmology, 2010, Feb-09, Volume: 10

    Topics: Aged; Aged, 80 and over; Aptamers, Nucleotide; Choroidal Neovascularization; Community Medicine; Drug Administration Schedule; Exudates and Transudates; Female; Fovea Centralis; Humans; Injections, Intraocular; Macular Degeneration; Male; Medical Records; Middle Aged; Professional Practice; Retrospective Studies; Treatment Outcome; United States; Vascular Endothelial Growth Factor A; Visual Acuity; Vitreous Body

2010
Ranibizumab vs. pegaptanib: a cost-effectiveness study?
    Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2010, Volume: 248, Issue:11

    Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Choroidal Neovascularization; Cost-Benefit Analysis; Costs and Cost Analysis; Health Care Costs; Health Services Research; Humans; Macular Degeneration; Quality-Adjusted Life Years; Ranibizumab; Visual Acuity

2010
[Retinal angiomatous proliferation with associated pigment epithelium detachment: anti-VEGF therapy].
    Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft, 2011, Volume: 108, Issue:3

    Topics: Aged; Aged, 80 and over; Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Bevacizumab; Choroidal Neovascularization; Female; Fluorescein Angiography; Follow-Up Studies; Humans; Indocyanine Green; Intravitreal Injections; Macular Degeneration; Male; Ophthalmoscopes; Ranibizumab; Retina; Retinal Detachment; Retinal Neovascularization; Retrospective Studies; Tomography, Optical Coherence; Vascular Endothelial Growth Factor A; Visual Acuity

2011
Antivascular endothelial growth factors in age-related macular degeneration.
    Developments in ophthalmology, 2010, Volume: 46

    Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Bevacizumab; Choroidal Neovascularization; Humans; Injections, Intraocular; Macular Degeneration; Ranibizumab; Vascular Endothelial Growth Factor A; Vitreous Body

2010
Intravitreal triamcinolone, bevacizumab and pegaptanib for occult choroidal neovascularization.
    Acta ophthalmologica, 2010, Volume: 88, Issue:8

    Topics: Aged; Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Bevacizumab; Choroidal Neovascularization; Female; Fluorescein Angiography; Follow-Up Studies; Fovea Centralis; Glucocorticoids; Humans; Intraocular Pressure; Intravitreal Injections; Macular Degeneration; Male; Prognosis; Retreatment; Retrospective Studies; Tomography, Optical Coherence; Triamcinolone Acetonide; Vascular Endothelial Growth Factor A; Visual Acuity

2010
[Exsudative age-related macular degeneration treatment results in patients registered in the nation-wide AMADEUS register].
    Ceska a slovenska oftalmologie : casopis Ceske oftalmologicke spolecnosti a Slovenske oftalmologicke spolecnosti, 2010, Volume: 66, Issue:3

    Topics: Aged; Aged, 80 and over; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Czech Republic; Female; Humans; Macular Degeneration; Male; Middle Aged; Photochemotherapy; Porphyrins; Ranibizumab; Registries; Verteporfin; Visual Acuity

2010
[Reimbursement of medical expenses of the exsudative age-related macular degeneration treatment from the public health insurance].
    Ceska a slovenska oftalmologie : casopis Ceske oftalmologicke spolecnosti a Slovenske oftalmologicke spolecnosti, 2010, Volume: 66, Issue:3

    Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Czech Republic; Humans; Insurance, Health, Reimbursement; Macular Degeneration; Photochemotherapy; Porphyrins; Ranibizumab; Verteporfin

2010
[Sodium pegaptanib and ranibizumab in the treatment of the retinal pigment layer ablation in a patient with age-related macular degeneration--a case report].
    Ceska a slovenska oftalmologie : casopis Ceske oftalmologicke spolecnosti a Slovenske oftalmologicke spolecnosti, 2010, Volume: 66, Issue:3

    Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Female; Fluorescein Angiography; Humans; Intravitreal Injections; Macular Degeneration; Middle Aged; Ranibizumab; Retinal Pigment Epithelium; Tomography, Optical Coherence; Visual Acuity

2010
[The change of the anti-VEGF agent in the treatment of exceptionally active choroidal neovascular membrane in age-related macular degeneration].
    Ceska a slovenska oftalmologie : casopis Ceske oftalmologicke spolecnosti a Slovenske oftalmologicke spolecnosti, 2010, Volume: 66, Issue:3

    Topics: Aged, 80 and over; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Choroidal Neovascularization; Drug Substitution; Fluorescein Angiography; Humans; Intravitreal Injections; Macular Degeneration; Male; Ranibizumab; Tomography, Optical Coherence; Vascular Endothelial Growth Factors

2010
Effect of prophylactic intraocular pressure-lowering medication on intraocular pressure spikes after intravitreal injections.
    Archives of ophthalmology (Chicago, Ill. : 1960), 2010, Volume: 128, Issue:12

    Topics: Aged, 80 and over; Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antihypertensive Agents; Aptamers, Nucleotide; Bevacizumab; Female; Humans; Intraocular Pressure; Intravitreal Injections; Macular Degeneration; Male; Ocular Hypertension; Ranibizumab; Retrospective Studies; Tonometry, Ocular; Vascular Endothelial Growth Factor A; Visual Acuity

2010
Generalized pairwise comparisons of prioritized outcomes in the two-sample problem.
    Statistics in medicine, 2010, Dec-30, Volume: 29, Issue:30

    Topics: Antineoplastic Combined Chemotherapy Protocols; Aptamers, Nucleotide; Colorectal Neoplasms; Disease-Free Survival; Fluorouracil; Humans; Leucovorin; Macular Degeneration; Organoplatinum Compounds; Oxaliplatin; Randomized Controlled Trials as Topic; Statistics as Topic; Treatment Outcome; Visual Acuity

2010
The safety of using anti-VEGF: Is there strength in numbers? Curtis LH, Hammill BG, Schulman KA, Cousins SW (2010) Risks of mortality, myocardial infarction, bleeding, and stroke associated with therapies for age-related macular degeneration. Arch Ophthal
    Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2011, Volume: 249, Issue:2

    Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Bevacizumab; Cause of Death; Hemorrhage; Humans; Macular Degeneration; Myocardial Infarction; Photochemotherapy; Ranibizumab; Risk Factors; Stroke; Vascular Endothelial Growth Factor A

2011
Pharmacotherapy for neovascular age-related macular degeneration: an analysis of the 100% 2008 medicare fee-for-service part B claims file.
    American journal of ophthalmology, 2011, Volume: 151, Issue:5

    Topics: Aged; Aged, 80 and over; Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Bevacizumab; Choroidal Neovascularization; Drug Therapy; Drug Utilization Review; Fee-for-Service Plans; Female; Humans; Intravitreal Injections; Macular Degeneration; Male; Medicare Part B; Middle Aged; Porphyrins; Ranibizumab; Retrospective Studies; United States; Vascular Endothelial Growth Factor A; Verteporfin

2011
Retreatment criteria in anti-VEGF therapy of exudative AMD: critical analysis of present regimes and new morphological definition of "lesion activity".
    Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2011, Volume: 249, Issue:5

    Topics: Algorithms; Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Decision Trees; European Union; Exudates and Transudates; Humans; Macular Degeneration; Practice Guidelines as Topic; Ranibizumab; Recurrence; Retreatment; Vascular Endothelial Growth Factor A; Visual Acuity

2011
[Results of an expert survey on VEGF inhibitors in ophthalmology].
    Klinische Monatsblatter fur Augenheilkunde, 2011, Volume: 228, Issue:7

    Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Bevacizumab; Data Collection; Diabetic Retinopathy; Germany; Humans; Interviews as Topic; Intravitreal Injections; Macular Degeneration; Ophthalmology; Practice Patterns, Physicians'; Ranibizumab; Vascular Endothelial Growth Factor A

2011
Ocular complications after anti-vascular endothelial growth factor therapy in Medicare patients with age-related macular degeneration.
    American journal of ophthalmology, 2011, Volume: 152, Issue:2

    Topics: Aged, 80 and over; Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Bevacizumab; Case-Control Studies; Endophthalmitis; Eye Diseases; Female; Follow-Up Studies; Health Services Research; Humans; Incidence; Intravitreal Injections; Macular Degeneration; Male; Medicare Part B; Proportional Hazards Models; Ranibizumab; Retinal Detachment; Retinal Perforations; Retrospective Studies; United States; Uveitis; Vascular Endothelial Growth Factor A; Vitreous Hemorrhage

2011
Long-term visual outcome of pigment epithelial tears in association with anti-VEGF therapy of pigment epithelial detachment in AMD.
    Eye (London, England), 2011, Volume: 25, Issue:9

    Topics: Aged; Aged, 80 and over; Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Bevacizumab; Female; Fluorescein Angiography; Humans; Intravitreal Injections; Macular Degeneration; Male; Middle Aged; Pigment Epithelium of Eye; Ranibizumab; Retinal Detachment; Retinal Perforations; Tomography, Optical Coherence; Vascular Endothelial Growth Factors; Visual Acuity

2011
Endophthalmitis after intravitreal vascular [corrected] endothelial growth factor antagonists: a six-year experience at a university referral center.
    Retina (Philadelphia, Pa.), 2011, Volume: 31, Issue:4

    Topics: Academic Medical Centers; Aged; Aged, 80 and over; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Aqueous Humor; Bacteria; Bevacizumab; Endophthalmitis; Eye Infections, Bacterial; Female; Humans; Intravitreal Injections; Macular Degeneration; Male; Middle Aged; Ranibizumab; Referral and Consultation; Retrospective Studies; Vascular Endothelial Growth Factor A; Visual Acuity; Vitreous Body

2011
Sustained elevated intraocular pressures after intravitreal injection of bevacizumab, ranibizumab, and pegaptanib.
    Retina (Philadelphia, Pa.), 2011, Volume: 31, Issue:6

    Topics: Aged, 80 and over; Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antihypertensive Agents; Aptamers, Nucleotide; Bevacizumab; Female; Filtering Surgery; Humans; Intraocular Pressure; Intravitreal Injections; Macular Degeneration; Male; Ocular Hypertension; Ranibizumab; Retreatment; Retrospective Studies; Tonometry, Ocular; Vascular Endothelial Growth Factor A; Visual Acuity

2011
[Complications of intravitreal injections--own experience].
    Klinika oczna, 2011, Volume: 113, Issue:4-6

    Topics: Aged; Anti-Inflammatory Agents; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Bevacizumab; Conjunctival Diseases; Diabetic Retinopathy; Endophthalmitis; Eye Diseases; Eye Hemorrhage; Female; Follow-Up Studies; Glucocorticoids; Humans; Inflammation; Intravitreal Injections; Iris Diseases; Macular Degeneration; Macular Edema; Male; Middle Aged; Ocular Hypertension; Poland; Ranibizumab; Retinal Diseases; Retinal Vein Occlusion; Retrospective Studies; Risk Factors; Triamcinolone Acetonide; Visual Acuity

2011
[Cost-effectiveness of ranibizumab, photodynamic therapy and pegaptanib sodium in the treatment of neovascular age-related macular degeneration in Japanese].
    Nippon Ganka Gakkai zasshi, 2011, Volume: 115, Issue:9

    Topics: Aged; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Asian People; Choroidal Neovascularization; Cost-Benefit Analysis; Humans; Macular Degeneration; Male; Photochemotherapy; Ranibizumab; Vascular Endothelial Growth Factor A

2011
[Intravitreal injections: AFSSAPS guide to good practice].
    Journal francais d'ophtalmologie, 2012, Volume: 35, Issue:1

    Topics: Aptamers, Nucleotide; Diabetic Retinopathy; Endophthalmitis; France; Humans; Intravitreal Injections; Macular Degeneration; Ophthalmologic Surgical Procedures; Postoperative Complications; Practice Guidelines as Topic; Retinal Diseases; Retinal Vein Occlusion; Societies, Medical

2012
Cost-effectiveness analysis of ranibizumab versus verteporfin photodynamic therapy, pegaptanib sodium, and best supportive care for the treatment of age-related macular degeneration in Greece.
    Clinical therapeutics, 2012, Volume: 34, Issue:2

    Topics: Aged; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Cost-Benefit Analysis; Health Care Costs; Humans; Macular Degeneration; Markov Chains; Photochemotherapy; Porphyrins; Quality-Adjusted Life Years; Ranibizumab; Verteporfin

2012
Retinal function and morphology in rabbit after intravitreal injection of VEGF inhibitors.
    Current eye research, 2012, Volume: 37, Issue:5

    Topics: Angiogenesis Inhibitors; Animals; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Bevacizumab; Disease Models, Animal; Electroretinography; Immunohistochemistry; Intravitreal Injections; Macular Degeneration; Rabbits; Ranibizumab; Retina; Vascular Endothelial Growth Factor A

2012
[The effect comparison of ranibizumab and sodium pegaptanib on the retinal pigment epithelium ablation size in the treatment of age-related macular degeneration].
    Ceska a slovenska oftalmologie : casopis Ceske oftalmologicke spolecnosti a Slovenske oftalmologicke spolecnosti, 2012, Volume: 68, Issue:2

    Topics: Aged; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Female; Humans; Macular Degeneration; Male; Ranibizumab; Retinal Pigment Epithelium; Tomography, Optical Coherence; Vascular Endothelial Growth Factor A

2012
Effects of treatment change in patients with neovascular age-related macular degeneration; results from the Czech National Registry.
    Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia, 2012, Volume: 156, Issue:4

    Topics: Aged; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Czech Republic; Female; Humans; Macular Degeneration; Male; Ranibizumab; Registries; Retrospective Studies; Treatment Failure

2012
Pegaptanib sodium.
    Nature reviews. Drug discovery, 2005, Volume: 4, Issue:3

    Topics: Aptamers, Nucleotide; Double-Blind Method; Humans; Macular Degeneration; Oligonucleotides; Randomized Controlled Trials as Topic; Treatment Outcome; Vascular Endothelial Growth Factor A

2005
New treatments for age-related macular degeneration.
    Ophthalmology, 2005, Volume: 112, Issue:4

    Topics: Aptamers, Nucleotide; Dietary Supplements; Humans; Laser Coagulation; Macular Degeneration; Oligonucleotides; Ophthalmologic Surgical Procedures; Photochemotherapy; Pregnadienediols

2005
Aptamers: slowing progression of AMD.
    Managed care (Langhorne, Pa.), 2005, Volume: 14, Issue:3

    Topics: Age Factors; Aptamers, Nucleotide; Disease Progression; Humans; Macular Degeneration; Oligonucleotides; United States; Vision, Ocular

2005
Pegaptanib and age-related macular degeneration.
    The New England journal of medicine, 2005, Apr-21, Volume: 352, Issue:16

    Topics: Aptamers, Nucleotide; Choroidal Neovascularization; Dose-Response Relationship, Drug; Humans; Injections; Macular Degeneration; Oligonucleotides; Vitreous Body

2005
New drug treats form of age-related macular degeneration. Macugen inhibits progression of wet AMD and also may restore some vision.
    Health news (Waltham, Mass.), 2005, Volume: 11, Issue:5

    Topics: Aged; Angiogenesis Inhibitors; Aptamers, Nucleotide; Humans; Macular Degeneration; Oligonucleotides

2005
Pegaptanib sodium (Macugen) for macular degeneration.
    The Medical letter on drugs and therapeutics, 2005, Jul-04, Volume: 47, Issue:1212

    Topics: Aptamers, Nucleotide; Humans; Injections; Macular Degeneration; Oligonucleotides; Vision Disorders; Vitreous Body

2005
[Antiangiogenic therapy].
    Archivos de la Sociedad Espanola de Oftalmologia, 2005, Volume: 80, Issue:8

    Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Choroidal Neovascularization; Clinical Trials as Topic; Eye Proteins; Humans; Macular Degeneration; Nerve Growth Factors; Photochemotherapy; Ranibizumab; Serpins; Vascular Endothelial Growth Factor A

2005
[Antiangiogenesis therapy of age-related macular degeneration].
    Ugeskrift for laeger, 2005, Aug-29, Volume: 167, Issue:35

    Topics: Aged; Angiogenesis Inhibitors; Aptamers, Nucleotide; Humans; Injections; Macular Degeneration; Oligonucleotides; Vascular Endothelial Growth Factors; Vitreous Body

2005
A therapeutic aptamer inhibits angiogenesis by specifically targeting the heparin binding domain of VEGF165.
    Proceedings of the National Academy of Sciences of the United States of America, 2005, Dec-27, Volume: 102, Issue:52

    Topics: Aptamers, Nucleotide; Binding Sites; Binding, Competitive; Cells, Cultured; Dimerization; Endothelium, Vascular; Heparin; Humans; Macular Degeneration; Magnetic Resonance Spectroscopy; Models, Molecular; Neovascularization, Pathologic; Pichia; Polyethylene Glycols; Protein Binding; Protein Conformation; Protein Isoforms; Protein Structure, Secondary; Protein Structure, Tertiary; Pyrimidines; RNA; Signal Transduction; Thermodynamics; Vascular Endothelial Growth Factor A

2005
Short-term intraocular pressure trends following intravitreal pegaptanib (Macugen) injection.
    American journal of ophthalmology, 2006, Volume: 141, Issue:1

    Topics: Aptamers, Nucleotide; Humans; Injections; Intraocular Pressure; Macular Degeneration; Retrospective Studies; Tonometry, Ocular; Vitreous Body

2006
Age-related macular degeneration: options for earlier detection and improved treatment.
    The Journal of family practice, 2006, Volume: 55, Issue:1

    Topics: Aged; Aged, 80 and over; Aptamers, Nucleotide; Humans; Hypertension; Low-Level Light Therapy; Macular Degeneration; Risk Factors; Smoking; Visual Acuity; Vitamins

2006
New treatments for AMD.
    Ophthalmology, 2006, Volume: 113, Issue:1

    Topics: Aptamers, Nucleotide; Humans; Macular Degeneration; Vascular Endothelial Growth Factor A

2006
New perspectives on the treatment of age-related macular degeneration.
    Drugs of today (Barcelona, Spain : 1998), 2005, Volume: 41, Issue:11

    Topics: Age Factors; Angiogenesis Inhibitors; Aptamers, Nucleotide; Choroidal Neovascularization; Combined Modality Therapy; Genetic Therapy; Humans; Light Coagulation; Macular Degeneration; Photochemotherapy

2005
Pegaptanib for wet macular degeneration.
    Drugs of today (Barcelona, Spain : 1998), 2005, Volume: 41, Issue:11

    Topics: Age Factors; Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Choroidal Neovascularization; Clinical Trials as Topic; Humans; Light Coagulation; Macular Degeneration; Molecular Structure; Photochemotherapy; Ranibizumab; Vascular Endothelial Growth Factor A; Vitamins

2005
New drugs 06, part I.
    Nursing, 2006, Volume: 36, Issue:2

    Topics: Acamprosate; Adenine Nucleotides; Alcohol Deterrents; Amyloid; Analgesics, Non-Narcotic; Anti-HIV Agents; Antifungal Agents; Antineoplastic Agents; Aptamers, Nucleotide; Arabinonucleosides; Azabicyclo Compounds; Benzofurans; Clofarabine; Drug Approval; Drug Therapy; Drug-Related Side Effects and Adverse Reactions; Echinocandins; Exenatide; Fibroblast Growth Factor 7; Guanine; Humans; Hypoglycemic Agents; Islet Amyloid Polypeptide; Lipopeptides; Lipoproteins; Macular Degeneration; Micafungin; omega-Conotoxins; Patient Education as Topic; Peptides; Peptides, Cyclic; Piperazines; Pyrrolidines; Quinuclidines; Solifenacin Succinate; Stomatitis; Taurine; Tetrahydroisoquinolines; Urinary Incontinence; Venoms

2006
Six-week outcomes after pegaptanib.
    Ophthalmology, 2006, Volume: 113, Issue:3

    Topics: Aptamers, Nucleotide; Humans; Macular Degeneration; Time Factors; Tomography, Optical Coherence; Treatment Outcome; Visual Acuity; Vitreous Body

2006
Retinal pigment epithelial tear following intravitreal pegaptanib sodium.
    American journal of ophthalmology, 2006, Volume: 141, Issue:4

    Topics: Aged; Aptamers, Nucleotide; Choroidal Neovascularization; Female; Fluorescein Angiography; Humans; Indocyanine Green; Injections; Macular Degeneration; Male; Pigment Epithelium of Eye; Retinal Detachment; Retinal Perforations; Tomography, Optical Coherence; Visual Acuity

2006
[Comments on current therapeutic possibilities for neovascular age-related macula degeneration].
    Klinische Monatsblatter fur Augenheilkunde, 2006, Volume: 223, Issue:4

    Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Choroidal Neovascularization; Germany; Glucocorticoids; Humans; Laser Coagulation; Macular Degeneration; Photochemotherapy; Porphyrins; Practice Guidelines as Topic; Practice Patterns, Physicians'; Pregnadienediols; Ranibizumab; Triamcinolone; Verteporfin

2006
A 76-year-old man with macular degeneration.
    JAMA, 2006, May-24, Volume: 295, Issue:20

    Topics: Aged; Angiogenesis Inhibitors; Antioxidants; Aptamers, Nucleotide; Humans; Laser Coagulation; Macular Degeneration; Male; Risk Factors; Vascular Endothelial Growth Factor A

2006
Retinal pigment epithelial tears after pegaptanib injection for exudative age-related macular degeneration.
    American journal of ophthalmology, 2006, Volume: 142, Issue:1

    Topics: Aged; Aptamers, Nucleotide; Exudates and Transudates; Female; Fluorescein Angiography; Humans; Injections; Macular Degeneration; Pigment Epithelium of Eye; Retinal Perforations; Rupture

2006
Macular degeneration. Advances in treatment.
    Mayo Clinic health letter (English ed.), 2006, Volume: 24, Issue:7

    Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antioxidants; Aptamers, Nucleotide; Glucocorticoids; Humans; Light Coagulation; Macular Degeneration; Photochemotherapy; Pregnadienediols; Ranibizumab; Triamcinolone

2006
[Medical and legal issues related to the drugs currently used in the treatment of Age-Related Macular Degeneration (ARMD)].
    Archivos de la Sociedad Espanola de Oftalmologia, 2006, Volume: 81, Issue:7

    Topics: Aptamers, Nucleotide; Drug Utilization; Humans; Macular Degeneration; Photosensitizing Agents; Porphyrins; Spain; Triamcinolone Acetonide; Verteporfin

2006
Readers' responses to "the cost of marginal medicine is too high".
    MedGenMed : Medscape general medicine, 2006, May-15, Volume: 8, Issue:2

    Topics: Aptamers, Nucleotide; Health Care Costs; Humans; Macular Degeneration; Medicare

2006
Evolving European guidance on the medical management of neovascular age related macular degeneration.
    The British journal of ophthalmology, 2006, Volume: 90, Issue:9

    Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Choroidal Neovascularization; Evidence-Based Medicine; Humans; Macular Degeneration; Photochemotherapy; Pregnadienediols; Ranibizumab; Treatment Outcome; Triamcinolone Acetonide

2006
Antivascular endothelial growth factor agents and their development: therapeutic implications in ocular diseases.
    American journal of ophthalmology, 2006, Volume: 142, Issue:4

    Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Bevacizumab; Humans; Macular Degeneration; Ranibizumab; Vascular Endothelial Growth Factor A

2006
Progression of choroidal neovascularization following injection of pegaptanib sodium (macugen) in two eyes with neovascular age-related macular degeneration.
    American journal of ophthalmology, 2006, Volume: 142, Issue:4

    Topics: Aged; Angiogenesis Inhibitors; Aptamers, Nucleotide; Choroidal Neovascularization; Disease Progression; Female; Fluorescein Angiography; Humans; Injections; Macular Degeneration; Male; Middle Aged; Vascular Endothelial Growth Factor A; Vitreous Body

2006
New treatments for age-related macular degeneration.
    Age and ageing, 2007, Volume: 36, Issue:1

    Topics: Aged; Aged, 80 and over; Aging; Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Bevacizumab; Choroidal Neovascularization; Humans; Light Coagulation; Macular Degeneration; Photochemotherapy; Randomized Controlled Trials as Topic; Ranibizumab; Vascular Endothelial Growth Factor A

2007
[Age-related macular degeneration: therapeutic hopes].
    Medecine sciences : M/S, 2007, Volume: 23, Issue:2

    Topics: Age of Onset; Aged; Aged, 80 and over; Aging; Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Bevacizumab; Double-Blind Method; Female; Genetic Predisposition to Disease; Humans; Macular Degeneration; Male; Middle Aged; Multicenter Studies as Topic; Randomized Controlled Trials as Topic; Ranibizumab; Vascular Endothelial Growth Factor A

2007
A value-based medicine comparison of interventions for subfoveal neovascular macular degeneration.
    Ophthalmology, 2007, Volume: 114, Issue:6

    Topics: Aptamers, Nucleotide; Choroidal Neovascularization; Clinical Trials as Topic; Cost of Illness; Cost-Benefit Analysis; Economics, Medical; Evidence-Based Medicine; Fovea Centralis; Health Care Costs; Humans; Laser Coagulation; Macular Degeneration; Photochemotherapy; Photosensitizing Agents; Porphyrins; Quality of Life; Quality-Adjusted Life Years; Verteporfin; Visual Acuity

2007
Intraocular pressure effects of pegaptanib (Macugen) injections in patients with and without glaucoma.
    American journal of ophthalmology, 2007, Volume: 143, Issue:6

    Topics: Aged; Antihypertensive Agents; Aptamers, Nucleotide; Chronic Disease; Glaucoma, Open-Angle; Humans; Injections; Intraocular Pressure; Macular Degeneration; Retrospective Studies; Time Factors; Tonometry, Ocular; Vascular Endothelial Growth Factor A; Vitreous Body

2007
New outlook for age-related macular degeneration.
    Nursing, 2007, Volume: 37, Issue:3

    Topics: Aged; Aging; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Fluorescein Angiography; Humans; Light Coagulation; Macular Degeneration; Nursing Assessment; Patient Education as Topic; Photochemotherapy; Ranibizumab; Tomography, Optical Coherence

2007
[A new drug for macular degeneration. A breakthrough accomplished (interview by Waldtraud Paukstadt)].
    MMW Fortschritte der Medizin, 2007, Jan-18, Volume: 149, Issue:3

    Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Bevacizumab; Drug Costs; Germany; Humans; Macular Degeneration; Ranibizumab; Treatment Outcome

2007
Quantitative comparison of optical coherence tomography after pegaptanib or bevacizumab in neovascular age-related macular degeneration.
    Ophthalmology, 2008, Volume: 115, Issue:2

    Topics: Aged; Aged, 80 and over; Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Bevacizumab; Choroidal Neovascularization; Female; Humans; Injections; Macular Degeneration; Male; Retina; Retrospective Studies; Tomography, Optical Coherence; Treatment Outcome; Vascular Endothelial Growth Factor A; Visual Acuity; Vitreous Body

2008
[Position of the Retinological Society, the German Ophthalmological Society and the Professional Association of Ophthalmologists in Germany on the current therapeutic possibilities for neovascular age-related macular degeneration].
    Klinische Monatsblatter fur Augenheilkunde, 2007, Volume: 224, Issue:7

    Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Bevacizumab; Choroidal Neovascularization; Drug Therapy, Combination; Evidence-Based Medicine; Humans; Macular Degeneration; Ophthalmology; Photochemotherapy; Porphyrins; Pregnadienediols; Ranibizumab; Societies, Medical; Triamcinolone Acetonide; Vascular Endothelial Growth Factor A; Verteporfin

2007
Macular degeneration, patients' groups, and pharma.
    Lancet (London, England), 2007, Jul-21, Volume: 370, Issue:9583

    Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Bevacizumab; Cost-Benefit Analysis; Humans; Macular Degeneration; National Health Programs; Patient Rights; Public Opinion; Ranibizumab; United Kingdom

2007
Clinical update: new treatments for age-related macular degeneration.
    Lancet (London, England), 2007, Jul-21, Volume: 370, Issue:9583

    Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Bevacizumab; Coronary Disease; Half-Life; Humans; Macular Degeneration; Randomized Controlled Trials as Topic; Ranibizumab; Treatment Outcome; Vascular Endothelial Growth Factor A

2007
Treatment of exudative age-related macular degeneration: many factors to consider.
    American journal of ophthalmology, 2007, Volume: 144, Issue:2

    Topics: Angiogenesis Inhibitors; Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Bevacizumab; Cost of Illness; Disease Models, Animal; Drug Costs; Humans; Injections; Macular Degeneration; Ranibizumab; Vascular Endothelial Growth Factor A; Vitreous Body

2007
Safety of intravitreal injections in patients receiving warfarin anticoagulation.
    American journal of ophthalmology, 2007, Volume: 144, Issue:3

    Topics: Aged; Aged, 80 and over; Angiogenesis Inhibitors; Anticoagulants; Aptamers, Nucleotide; Aspirin; Celecoxib; Choroidal Neovascularization; Drug Therapy, Combination; Eye Hemorrhage; Female; Humans; Injections; Macular Degeneration; Male; Middle Aged; Pyrazoles; Retrospective Studies; Sulfonamides; Vascular Endothelial Growth Factor A; Vitreous Body; Warfarin

2007
Cost effectiveness of pegaptanib for the treatment of age-related macular degeneration in the UK.
    PharmacoEconomics, 2007, Volume: 25, Issue:10

    Topics: Age Factors; Aged; Aged, 80 and over; Aptamers, Nucleotide; Clinical Trials as Topic; Cost-Benefit Analysis; Female; Humans; Macular Degeneration; Male; Markov Chains; Middle Aged; Models, Statistical; Quality-Adjusted Life Years; Reproducibility of Results; Sex Factors; Treatment Outcome; United Kingdom; Vascular Endothelial Growth Factor A; Visual Acuity

2007
Treatment of naïve lesions in neovascular age-related macular degeneration with pegaptanib.
    Retina (Philadelphia, Pa.), 2007, Volume: 27, Issue:7

    Topics: Aged; Aged, 80 and over; Angiogenesis Inhibitors; Aptamers, Nucleotide; Choroidal Neovascularization; Female; Fluorescein Angiography; Humans; Injections; Macular Degeneration; Male; Retrospective Studies; Tomography, Optical Coherence; Treatment Outcome; Vascular Endothelial Growth Factor A; Visual Acuity; Vitreous Body

2007
RPE tears after pegaptanib treatment in age-related macular degeneration.
    Retina (Philadelphia, Pa.), 2007, Volume: 27, Issue:7

    Topics: Aged; Aged, 80 and over; Angiogenesis Inhibitors; Aptamers, Nucleotide; Choroidal Neovascularization; Female; Fluorescein Angiography; Humans; Injections; Macular Degeneration; Male; Pigment Epithelium of Eye; Postoperative Complications; Retinal Perforations; Tomography, Optical Coherence; Vascular Endothelial Growth Factor A; Visual Acuity; Vitreous Body

2007
Multifocal electroretinography in patients with exudative amd and intravitreal treatment with pegaptanib sodium.
    Retina (Philadelphia, Pa.), 2007, Volume: 27, Issue:7

    Topics: Aged; Aged, 80 and over; Angiogenesis Inhibitors; Aptamers, Nucleotide; Choroidal Neovascularization; Electroretinography; Exudates and Transudates; Female; Humans; Injections; Macular Degeneration; Male; Middle Aged; Retina; Vascular Endothelial Growth Factor A; Visual Acuity; Vitreous Body

2007
New treatments for age-related macular degeneration.
    Lancet (London, England), 2007, Oct-27, Volume: 370, Issue:9597

    Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Bevacizumab; Dose-Response Relationship, Drug; Humans; Macular Degeneration; Ranibizumab; Vascular Endothelial Growth Factor A

2007
New treatments for age-related macular degeneration.
    Lancet (London, England), 2007, Oct-27, Volume: 370, Issue:9597

    Topics: Angiogenesis Inhibitors; Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Bevacizumab; Humans; Macular Degeneration; Rabbits; Ranibizumab; Reference Values

2007
Drug delivery to the back of the eye.
    Archivos de la Sociedad Espanola de Oftalmologia, 2007, Volume: 82, Issue:11

    Topics: Antiviral Agents; Aptamers, Nucleotide; Clinical Trials, Phase III as Topic; Drug Administration Routes; Drug Delivery Systems; Eye Diseases; Glaucoma; Humans; Injections; Macular Degeneration; Nanoparticles; Oligonucleotides, Antisense; Ophthalmic Solutions; Retinal Diseases; Thionucleotides; Vascular Endothelial Growth Factor A

2007
[New therapeutic aspects in age-related macular degeneration].
    Medicina clinica, 2007, Nov-10, Volume: 129, Issue:17

    Topics: Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Clinical Trials, Phase III as Topic; Disease Progression; Forecasting; Humans; Macular Degeneration; Middle Aged; Multicenter Studies as Topic; Photochemotherapy; Photosensitizing Agents; Porphyrins; Randomized Controlled Trials as Topic; Ranibizumab; Risk Factors; Smoking; Smoking Cessation; Vascular Endothelial Growth Factor A; Verteporfin; Visual Acuity

2007
Cost-effectiveness of pegaptanib compared to photodynamic therapy with verteporfin and to standard care in the treatment of subfoveal wet age-related macular degeneration in Canada.
    Clinical therapeutics, 2007, Volume: 29, Issue:9

    Topics: Aged; Aged, 80 and over; Aptamers, Nucleotide; Canada; Cost-Benefit Analysis; Female; Fovea Centralis; Humans; Laser Coagulation; Macular Degeneration; Male; Models, Econometric; Photochemotherapy; Photosensitizing Agents; Porphyrins; Quality-Adjusted Life Years; Vascular Endothelial Growth Factor A; Verteporfin; Visual Acuity

2007
Intraocular pressure effects of pegaptanib (macugen) injections in patients with and without glaucoma.
    American journal of ophthalmology, 2008, Volume: 145, Issue:1

    Topics: Angiogenesis Inhibitors; Aptamers, Nucleotide; Chronic Disease; Glaucoma, Open-Angle; Humans; Injections; Intraocular Pressure; Macular Degeneration; Tonometry, Ocular; Vascular Endothelial Growth Factor A; Vitreous Body

2008
[The current state and issues of medical treatment for age-related macular degeneration].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 2008, Volume: 131, Issue:1

    Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Bevacizumab; Humans; Macular Degeneration; Ranibizumab; Vascular Endothelial Growth Factors

2008
AMD: out of sight out of mind.
    Nursing older people, 2007, Volume: 19, Issue:10

    Topics: Aged; Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Bevacizumab; Cost-Benefit Analysis; Drug Approval; Drug Costs; Drug Utilization; Geriatric Nursing; Health Promotion; Humans; Macular Degeneration; Nurse's Role; Ophthalmology; Practice Guidelines as Topic; Practice Patterns, Physicians'; Ranibizumab; Risk Factors; State Medicine; Treatment Outcome; United Kingdom

2007
Incidence of ocular hemorrhages in anticoagulated patients receiving repeated intravitreal injections.
    American journal of ophthalmology, 2008, Volume: 145, Issue:2

    Topics: Angiogenesis Inhibitors; Anticoagulants; Aptamers, Nucleotide; Aspirin; Choroidal Neovascularization; Drug Therapy, Combination; Eye Hemorrhage; Humans; Incidence; Injections; Macular Degeneration; Risk Factors; Vascular Endothelial Growth Factor A; Vitreous Body; Warfarin

2008
[Introduction to the topic: anti-VEGF therapy in the management of AMD].
    Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft, 2008, Volume: 105, Issue:2

    Topics: Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Choroidal Neovascularization; Endophthalmitis; Humans; Injections; Macular Degeneration; Postoperative Care; Ranibizumab; Time Factors; Tomography, Optical Coherence; Treatment Outcome; Vascular Endothelial Growth Factor A; Visual Acuity; Vitreous Body

2008
Correspondence.
    Retina (Philadelphia, Pa.), 2008, Volume: 28, Issue:3

    Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Aptamers, Nucleotide; Bevacizumab; Choroidal Neovascularization; Humans; Injections; Macular Degeneration; Treatment Outcome; Vascular Endothelial Growth Factor A; Visual Acuity; Vitreous Body

2008
Early response of retinal angiomatous proliferation treated with intravitreal pegaptanib: a retrospective review.
    Eye (London, England), 2009, Volume: 23, Issue:3

    Topics: Aged; Aged, 80 and over; Angiogenesis Inhibitors; Angiomatosis; Aptamers, Nucleotide; Drug Evaluation; Female; Follow-Up Studies; Humans; Injections, Intraocular; Macular Degeneration; Male; Middle Aged; Retinal Diseases; Retrospective Studies; Vascular Endothelial Growth Factor A; Visual Acuity

2009