Page last updated: 2024-08-17

allyl isothiocyanate and Disease Models, Animal

allyl isothiocyanate has been researched along with Disease Models, Animal in 22 studies

Research

Studies (22)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (9.09)29.6817
2010's13 (59.09)24.3611
2020's7 (31.82)2.80

Authors

AuthorsStudies
Aubdool, AA; Bodkin, JV; Brain, SD; Cox, P; Dupont, T; Fairman, E; Hashizume, Y; Ishii, N; Kato, T; Kitching, L; Newman, J; Omoto, K; Rawson, D; Ryckmans, T; Strover, J1
Gencoglu, H; Morde, AA; Orhan, C; Ozercan, IH; Padigaru, M; Sahin, K; Sahin, N; Tuzcu, M1
Luo, Y; Malewicz, N; Nie, H; Pan, J; Rong, J; Situ, Y; Tang, D; Verkhratsky, A; Wang, Y; Ye, K; Zhang, Z; Zhao, J; Zhu, T1
Chen, Y; Feng, ZM; Gao, JG; Li, CX; Li, YM; Lin, YM; Ma, H; Wan, XY; Xu, CF; Xu, P; Yu, CH; Zeng, H1
Fang, W; Li, Z; Wang, D; Wang, X; Wu, J; Wu, Q; Yao, Z1
Batallé, G; Cabarga, L; Pol, O1
Fasano, A; Larocca, M; Latronico, T; Liuzzi, GM; Milella, S; Rossano, R1
Jung, HJ; Kang, JH; Kim, MW; Namgung, H; Oh, SH; Park, SY; Phan, THL; Seo, SY; Yoon, YS1
Hashimoto, K; Horie, S; Imai, T; Matsumoto, K; Tashima, K1
Jia, J; Tu, W; Wu, Y; Xie, C; Xu, Y1
Condon, L; Curtright, A; Dhaka, A; Esancy, K; Feng, J; Kimball, C1
Altunay, S; Caglayan, B; Dalay, A; Erten, F; Gunal, MY; Juturu, V; Kilic, E; Orhan, C; Sahin, K; Tuzcu, M; Yulug, B1
Botaitis, S; Franco, R; Mantso, T; Mitsiogianni, M; Panayiotidis, MI; Pappa, A; Trafalis, DT; Vasantha Rupasinghe, HP; Zoumpourlis, V1
Kase, Y; Kono, T; Miyagi, C; Miyano, K; Mizuno, K; Omiya, Y; Suzuki, Y; Uezono, Y1
Boezio, AA; Cheung, E; Copeland, KW; Gavva, NR; Geuns-Meyer, S; Lee, J; Lehto, SG; Olivieri, P; Schenkel, LB; Wan, Q; Wang, W; Wells, MC; Youngblood, B1
Fan, X; Hu, Y; Li, X; Liu, Z; Myers, AC; Pasricha, PJ; Tse, CM; Xi, J; Yu, S; Yu, X1
Filipek, B; Sałat, K1
Aguilera, M; De Alba, J; Domènech, A; Fernández-Blanco, JA; Miralpeix, M; Prats, N; Tarrasón, G1
Kandasamy, R; Lee, AT; Morgan, MM1
Holden, JE; Jeong, Y1
Hagen, SJ; Hayashi, S; Kubo, Y; Matsui, H; Nakamura, E; Takahashi, N; Takeuchi, K; Yamaguchi, A1
Bock, E; Holzer, P; Mitrovic, M; Pabst, MA; Shahbazian, A1

Other Studies

22 other study(ies) available for allyl isothiocyanate and Disease Models, Animal

ArticleYear
Design and pharmacological evaluation of PF-4840154, a non-electrophilic reference agonist of the TrpA1 channel.
    Bioorganic & medicinal chemistry letters, 2011, Aug-15, Volume: 21, Issue:16

    Topics: Animals; Ankyrins; Calcium Channels; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Design; Edema; Humans; Mice; Mice, Knockout; Molecular Structure; Nerve Tissue Proteins; Pain; Piperazines; Pyrimidines; Rats; Stereoisomerism; Structure-Activity Relationship; Transient Receptor Potential Channels; TRPA1 Cation Channel; TRPC Cation Channels

2011
Allyl isothiocyanate attenuates LED light-induced retinal damage in rats: exploration for the potential molecular mechanisms.
    Cutaneous and ocular toxicology, 2021, Volume: 40, Issue:4

    Topics: Animals; Apoptosis; Disease Models, Animal; Humans; Isothiocyanates; Light Pollution; Lighting; Male; Mitochondria; Oxidative Stress; Protective Agents; Rats; Retina; Retinal Degeneration; Semiconductors

2021
Oxymatrine screened from Sophora flavescens by cell membrane immobilized chromatography relieves histamine-independent itch.
    The Journal of pharmacy and pharmacology, 2021, Dec-07, Volume: 73, Issue:12

    Topics: Alkaloids; Animals; Antipruritics; Cell Membrane; Chloroquine; Chromatography; Disease Models, Animal; Drug Discovery; Ganglia, Spinal; Histamine; Humans; Isothiocyanates; Male; Mice, Inbred C57BL; Molecular Docking Simulation; Oligopeptides; Phytotherapy; Plant Extracts; Pruritus; Quinolizines; RNA, Messenger; Sophora; TRPA1 Cation Channel

2021
Allyl isothiocyanate ameliorates lipid accumulation and inflammation in nonalcoholic fatty liver disease
    World journal of gastroenterology, 2019, Sep-14, Volume: 25, Issue:34

    Topics: AMP-Activated Protein Kinases; Animals; Cell Line; Diet, High-Fat; Disease Models, Animal; Down-Regulation; Hepatocytes; Humans; Inflammation; Isothiocyanates; Lipid Metabolism; Liver; Male; Mice; Mice, Inbred C57BL; NF-kappa B; Non-alcoholic Fatty Liver Disease; Palmitic Acid; Signal Transduction; Sirtuin 1; Up-Regulation

2019
Allyl isothiocyanate may reverse the expression of MRP1 in COPD rats via the Notch1 signaling pathway.
    Archives of pharmacal research, 2019, Volume: 42, Issue:11

    Topics: Animals; Cell Line; Diamines; Disease Models, Animal; Down-Regulation; Epithelial Cells; Humans; Isothiocyanates; Lipopolysaccharides; Lung; Male; Multidrug Resistance-Associated Proteins; Pulmonary Disease, Chronic Obstructive; Rats; Receptor, Notch1; Signal Transduction; Thiazoles; Transcription Factor HES-1; Up-Regulation

2019
Treatment with slow-releasing hydrogen sulfide donors inhibits the nociceptive and depressive-like behaviours accompanying chronic neuropathic pain: Endogenous antioxidant system activation.
    Journal of psychopharmacology (Oxford, England), 2020, Volume: 34, Issue:7

    Topics: Animals; Antioxidants; Anxiety; Behavior, Animal; Chronic Pain; Depression; Disease Models, Animal; Hydrogen Sulfide; Isothiocyanates; Male; Mice; Mice, Inbred C57BL; Neuralgia

2020
Neuroprotective potential of isothiocyanates in an in vitro model of neuroinflammation.
    Inflammopharmacology, 2021, Volume: 29, Issue:2

    Topics: Animals; Astrocytes; Cells, Cultured; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Inflammation; Isothiocyanates; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Neuroprotective Agents; Rats; Rats, Wistar; Reactive Oxygen Species; Sulfoxides

2021
Allyl Isothiocyanate Protects Acetaminophen-Induced Liver Injury via NRF2 Activation by Decreasing Spontaneous Degradation in Hepatocyte.
    Nutrients, 2020, Nov-23, Volume: 12, Issue:11

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Hepatocytes; Isothiocyanates; Liver; Mice; Mice, Inbred C57BL

2020
The rodent model of impaired gastric motility induced by allyl isothiocyanate, a pungent ingredient of wasabi, to evaluate therapeutic agents for functional dyspepsia.
    Journal of pharmacological sciences, 2021, Volume: 145, Issue:1

    Topics: Animals; Benzamides; Benzyl Compounds; Disease Models, Animal; Dyspepsia; Gastrointestinal Motility; Isothiocyanates; Male; Mice, Inbred Strains; Morpholines; Neostigmine; Panax; Phytotherapy; Plant Extracts; Thiazoles; Wasabia; Zanthoxylum; Zingiberaceae

2021
Transient Receptor Potential Ankyrin 1 and Substance P Mediate the Development of Gastric Mucosal Lesions in a Water Immersion Restraint Stress Rat Model.
    Digestion, 2018, Volume: 97, Issue:3

    Topics: Acetanilides; Animals; Disease Models, Animal; Ganglia, Spinal; Gastric Mucosa; Humans; Isothiocyanates; Male; Neurons; Purines; Rats; Rats, Wistar; Stomach Ulcer; Stress, Psychological; Substance P; TRPA1 Cation Channel

2018
A zebrafish and mouse model for selective pruritus via direct activation of TRPA1.
    eLife, 2018, 03-21, Volume: 7

    Topics: Animals; Animals, Genetically Modified; Disease Models, Animal; Evoked Potentials, Somatosensory; HEK293 Cells; Humans; Imiquimod; Isothiocyanates; Larva; Membrane Potentials; Mice; Neurons; Pruritus; TRPA1 Cation Channel; Zebrafish; Zebrafish Proteins

2018
Allyl isothiocyanate attenuates oxidative stress and inflammation by modulating Nrf2/HO-1 and NF-κB pathways in traumatic brain injury in mice.
    Molecular biology reports, 2019, Volume: 46, Issue:1

    Topics: Animals; Antioxidants; Brain Injuries; Brain Injuries, Traumatic; Cytokines; Disease Models, Animal; Glial Fibrillary Acidic Protein; Heme Oxygenase-1; Inflammation; Intercellular Adhesion Molecule-1; Interleukin-1beta; Interleukin-6; Isothiocyanates; Male; Membrane Proteins; Mice; Mice, Inbred C57BL; NF-E2-Related Factor 2; NF-kappa B; Oxidative Stress; Reactive Oxygen Species; Signal Transduction

2019
Allyl isothiocyanate regulates lysine acetylation and methylation marks in an experimental model of malignant melanoma.
    European journal of nutrition, 2020, Volume: 59, Issue:2

    Topics: Acetylation; Animals; Blotting, Western; Cells, Cultured; Disease Models, Animal; Humans; Isothiocyanates; Lysine; Melanoma; Methylation; Mice

2020
Goshajinkigan, a traditional Japanese medicine, prevents oxaliplatin-induced acute peripheral neuropathy by suppressing functional alteration of TRP channels in rat.
    Journal of pharmacological sciences, 2014, Volume: 125, Issue:1

    Topics: Acute Disease; Animals; Cold Temperature; Disease Models, Animal; Drugs, Chinese Herbal; Ganglia, Spinal; Gene Expression; Isothiocyanates; Male; Menthol; Nociception; Organoplatinum Compounds; Oxaliplatin; Peripheral Nervous System Diseases; Phytotherapy; Rats; Rats, Sprague-Dawley; RNA, Messenger; Transient Receptor Potential Channels; TRPA1 Cation Channel; TRPC Cation Channels; TRPM Cation Channels

2014
Development of novel azabenzofuran TRPA1 antagonists as in vivo tools.
    Bioorganic & medicinal chemistry letters, 2014, Aug-01, Volume: 24, Issue:15

    Topics: Animals; Calcium Channel Blockers; Calcium Channels; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Design; Heterocyclic Compounds, 3-Ring; Humans; Isothiocyanates; Molecular Structure; Nerve Tissue Proteins; Rats; Structure-Activity Relationship; Transient Receptor Potential Channels; TRPA1 Cation Channel; TRPC Cation Channels

2014
Allergen challenge sensitizes TRPA1 in vagal sensory neurons and afferent C-fiber subtypes in guinea pig esophagus.
    American journal of physiology. Gastrointestinal and liver physiology, 2015, Mar-15, Volume: 308, Issue:6

    Topics: Action Potentials; Allergens; Animals; Calcium Signaling; Disease Models, Animal; Eosinophilic Esophagitis; Eosinophils; Esophagus; Guinea Pigs; Isothiocyanates; Male; Mast Cells; Nerve Fibers, Unmyelinated; Nodose Ganglion; Ovalbumin; Sensation; Sensory Receptor Cells; Time Factors; Transient Receptor Potential Channels; Vagus Nerve

2015
Antinociceptive activity of transient receptor potential channel TRPV1, TRPA1, and TRPM8 antagonists in neurogenic and neuropathic pain models in mice.
    Journal of Zhejiang University. Science. B, 2015, Volume: 16, Issue:3

    Topics: Acetanilides; Analgesics; Animals; Benzamides; Capsaicin; Cold Temperature; Disease Models, Animal; Formaldehyde; Hyperalgesia; Isothiocyanates; Male; Mice; Neuralgia; Oximes; Paclitaxel; Pain Measurement; Purines; Thiophenes; Touch; Transient Receptor Potential Channels; TRPA1 Cation Channel; TRPM Cation Channels; TRPV Cation Channels

2015
Enhanced cough reflex in a model of bleomycin-induced lung fibrosis in guinea pigs.
    Clinical science (London, England : 1979), 2015, Volume: 129, Issue:12

    Topics: Animals; Bleomycin; Brain-Derived Neurotrophic Factor; Bronchoalveolar Lavage Fluid; Capsaicin; Citric Acid; Cough; Cytokines; Disease Models, Animal; Disease Progression; Gene Expression Regulation; Guinea Pigs; Ion Channels; Isothiocyanates; Lung; Male; Matrix Metalloproteinase 2; Pulmonary Fibrosis; Reflex, Abnormal; Time Factors

2015
Depression of home cage wheel running: a reliable and clinically relevant method to assess migraine pain in rats.
    The journal of headache and pain, 2017, Volume: 18, Issue:1

    Topics: Animals; Behavior, Animal; Disease Models, Animal; Female; Isothiocyanates; Migraine Disorders; Rats; Rats, Sprague-Dawley; Running; Serotonin 5-HT1 Receptor Agonists; Sumatriptan

2017
Lateral hypothalamic-induced alpha-adrenoceptor modulation occurs in a model of inflammatory pain in rats.
    Biological research for nursing, 2009, Volume: 10, Issue:4

    Topics: Adrenergic alpha-Antagonists; Animals; Carbachol; Cholinergic Agonists; Disease Models, Animal; Female; Hypothalamic Area, Lateral; Inflammation; Isothiocyanates; Nociceptors; Nursing Research; Pain; Rats; Rats, Sprague-Dawley; Reaction Time; Receptors, Adrenergic, alpha; Tarsus, Animal; Yohimbine

2009
Impairment by allyl isothiocyanate of gastric epithelial wound repair through inhibition of ion transporters.
    Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2008, Volume: 59, Issue:4

    Topics: Animals; Anion Transport Proteins; Ankyrins; Antiporters; Calcium Channels; Cell Line; Cell Survival; Disease Models, Animal; Dose-Response Relationship, Drug; Epithelial Cells; Gastric Mucosa; Gene Expression Regulation; Isothiocyanates; Male; Rats; Rats, Sprague-Dawley; SLC4A Proteins; Sodium-Bicarbonate Symporters; Time Factors; TRPA1 Cation Channel; TRPC Cation Channels; Wound Healing

2008
Chemo-nociceptive signalling from the colon is enhanced by mild colitis and blocked by inhibition of transient receptor potential ankyrin 1 channels.
    British journal of pharmacology, 2010, Volume: 160, Issue:6

    Topics: Acetanilides; Animals; Capsaicin; Colitis; Colon; Dextran Sulfate; Disease Models, Animal; Female; Gene Expression Regulation; Isothiocyanates; Mice; Morphine; Neurons, Afferent; Proto-Oncogene Proteins c-fos; Purines; Signal Transduction; Transient Receptor Potential Channels; TRPA1 Cation Channel

2010