Page last updated: 2024-08-17

allyl isothiocyanate and Ache

allyl isothiocyanate has been researched along with Ache in 19 studies

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's7 (36.84)29.6817
2010's11 (57.89)24.3611
2020's1 (5.26)2.80

Authors

AuthorsStudies
Bandell, M; Earley, TJ; Eid, SR; Hwang, SW; Patapoutian, A; Petrus, MJ; Story, GM; Viswanath, V1
Cravatt, BF; Dubin, AE; Evans, MJ; Macpherson, LJ; Marr, F; Patapoutian, A; Schultz, PG1
Baraldi, PG; Geppetti, P; Materazzi, S; Preti, D1
Aubdool, AA; Bodkin, JV; Brain, SD; Cox, P; Dupont, T; Fairman, E; Hashizume, Y; Ishii, N; Kato, T; Kitching, L; Newman, J; Omoto, K; Rawson, D; Ryckmans, T; Strover, J1
Dai, Y; Kogure, Y; Mabuchi, M; Nakao, S; Noguchi, K; Shimizu, T; Tanaka, A; Wang, S1
Aoki, S; Dai, Y; Duan, S; Ishikawa, M; Iwaoka, E; Kanda, H; Kogure, Y; Mizuta, K; Noguchi, K; Sonoda, H; Takeda, S; Wang, S; Yamamoto, S; Yang, Y1
Andersen, HH; Arendt-Nielsen, L; Gazerani, P; Lo Vecchio, S1
Dawson, CT; Hilgendorf, TN; Kandasamy, R; Morgan, MM1
Harano, N; Hitomi, S; Inenaga, K; Kuramitsu, S; Matoba, M; Matsuo, K; Miyano, K; Ono, K; Ota, Y; Seta, Y; Uezono, Y; Yamaguchi, K1
Cianchetti, C; Luvisetto, S; Vacca, V1
de Oliveira Borges, M; Fischer, L; Lavoranti, MI; Martynhak, BJ; Miksza, AF; Parada, CA; Sardi, NF; Tambeli, CH1
Holden, JE; Jeong, Y1
Dai, Y; Kobayashi, K; Na, R; Noguchi, K; Wang, S; Yamamoto, S; Yoshida, N; Yu, L1
Inoue, N; Ito, S; Kyoi, T; Nogawa, M; Tajima, K1
Carstens, E; Carstens, MI; Davoodi, A; Spradley, JM1
Dai, Y; Fukuoka, T; Higashi, T; Kobayashi, K; Noguchi, K; Obata, K; Tominaga, M; Wang, S; Yamamoto, S; Yamanaka, H1
Chiang, CY; Dostrovsky, JO; Hu, JW; Sessle, BJ; Wang, J; Xie, YF; Zhang, S1
Andrade, EL; Calixto, JB; Ferreira, J; Luiz, AP1
Cui, X; Dai, Y; Fukuoka, T; Kobayashi, K; Noguchi, K; Obata, K; Tominaga, M; Wang, S; Yamanaka, H1

Reviews

1 review(s) available for allyl isothiocyanate and Ache

ArticleYear
Transient receptor potential ankyrin 1 (TRPA1) channel as emerging target for novel analgesics and anti-inflammatory agents.
    Journal of medicinal chemistry, 2010, Jul-22, Volume: 53, Issue:14

    Topics: Analgesics; Animals; Anti-Inflammatory Agents; Asthma; Humans; Ion Channel Gating; Neurons; Pain; Peripheral Nervous System Diseases; Pulmonary Disease, Chronic Obstructive; Transient Receptor Potential Channels

2010

Other Studies

18 other study(ies) available for allyl isothiocyanate and Ache

ArticleYear
Noxious cold ion channel TRPA1 is activated by pungent compounds and bradykinin.
    Neuron, 2004, Mar-25, Volume: 41, Issue:6

    Topics: Acrolein; Animals; Behavior, Animal; Bradykinin; Cell Membrane; CHO Cells; Cold Temperature; Cricetinae; Dose-Response Relationship, Drug; Humans; Inflammation Mediators; Ion Channels; Membrane Potentials; Mice; Neurons, Afferent; Nociceptors; Pain; Pain Measurement; Rats; Transient Receptor Potential Channels; TRPA1 Cation Channel; Type C Phospholipases

2004
Noxious compounds activate TRPA1 ion channels through covalent modification of cysteines.
    Nature, 2007, Feb-01, Volume: 445, Issue:7127

    Topics: Acrolein; Animals; Cysteine; Disulfides; Dithiothreitol; Electric Conductivity; Ethyl Methanesulfonate; Humans; Ion Channel Gating; Mice; Mustard Plant; Noxae; Pain; Plant Oils; Transient Receptor Potential Channels

2007
Design and pharmacological evaluation of PF-4840154, a non-electrophilic reference agonist of the TrpA1 channel.
    Bioorganic & medicinal chemistry letters, 2011, Aug-15, Volume: 21, Issue:16

    Topics: Animals; Ankyrins; Calcium Channels; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Design; Edema; Humans; Mice; Mice, Knockout; Molecular Structure; Nerve Tissue Proteins; Pain; Piperazines; Pyrimidines; Rats; Stereoisomerism; Structure-Activity Relationship; Transient Receptor Potential Channels; TRPA1 Cation Channel; TRPC Cation Channels

2011
Synthesis of resveratrol derivatives as new analgesic drugs through desensitization of the TRPA1 receptor.
    Bioorganic & medicinal chemistry letters, 2017, 07-15, Volume: 27, Issue:14

    Topics: Analgesics; Animals; Calcium Channels; Ganglia, Spinal; HEK293 Cells; Humans; Inhibitory Concentration 50; Nerve Tissue Proteins; Pain; Patch-Clamp Techniques; Rats; Resveratrol; Stilbenes; Transient Receptor Potential Channels; TRPA1 Cation Channel

2017
Atractylodin Produces Antinociceptive Effect through a Long-Lasting TRPA1 Channel Activation.
    International journal of molecular sciences, 2021, Mar-31, Volume: 22, Issue:7

    Topics: Analgesics; Animals; Calcium; Calcium Channels; Furans; Ganglia, Spinal; HEK293 Cells; Humans; Isothiocyanates; Lidocaine; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Neurons; Nociception; Nociceptors; Pain; Rats; Rats, Sprague-Dawley; Transient Receptor Potential Channels; TRPA1 Cation Channel; TRPC Cation Channels

2021
Dose-response study of topical allyl isothiocyanate (mustard oil) as a human surrogate model of pain, hyperalgesia, and neurogenic inflammation.
    Pain, 2017, Volume: 158, Issue:9

    Topics: Administration, Topical; Adult; Dose-Response Relationship, Drug; Female; Functional Laterality; Healthy Volunteers; Humans; Hyperalgesia; Isothiocyanates; Male; Models, Theoretical; Neurogenic Inflammation; Pain; Pain Measurement; Pain Threshold; Physical Stimulation; Pigmentation; Random Allocation; TRPA1 Cation Channel; Young Adult

2017
Medication overuse headache following repeated morphine, but not [INCREMENT]9-tetrahydrocannabinol administration in the female rat.
    Behavioural pharmacology, 2018, Volume: 29, Issue:5

    Topics: Analgesics, Opioid; Animals; Dronabinol; Drug Tolerance; Dura Mater; Female; Headache Disorders, Secondary; Injections, Intraperitoneal; Isothiocyanates; Migraine Disorders; Models, Animal; Morphine; Motor Activity; Pain; Pain Measurement; Rats; Rats, Sprague-Dawley

2018
Novel methods of applying direct chemical and mechanical stimulation to the oral mucosa for traditional behavioral pain assays in conscious rats.
    Journal of neuroscience methods, 2015, Jan-15, Volume: 239

    Topics: Animals; Capsaicin; Consciousness; Grooming; Hyperalgesia; Isothiocyanates; Male; Mouth Mucosa; Pain; Pain Measurement; Pain Threshold; Physical Stimulation; Rats; Rats, Sprague-Dawley; Skin; Stimulation, Chemical; Time Factors

2015
Analgesic effects of botulinum neurotoxin type A in a model of allyl isothiocyanate- and capsaicin-induced pain in mice.
    Toxicon : official journal of the International Society on Toxinology, 2015, Volume: 94

    Topics: Analgesics; Animals; Botulinum Toxins, Type A; Capsaicin; Isothiocyanates; Male; Mice; Mice, Inbred C57BL; Pain

2015
TRPA1, substance P, histamine and 5-hydroxytryptamine interact in an interdependent way to induce nociception.
    Inflammation research : official journal of the European Histamine Research Society ... [et al.], 2017, Volume: 66, Issue:4

    Topics: Acetanilides; Animals; Histamine; Histamine H1 Antagonists; Isothiocyanates; Male; Oligonucleotides, Antisense; p-Methoxy-N-methylphenethylamine; Pain; Piperazines; Purines; Pyrilamine; Quinuclidines; Rats, Wistar; Receptor, Serotonin, 5-HT1A; Receptors, Histamine H1; Receptors, Neurokinin-1; Receptors, Serotonin, 5-HT3; Serotonin; Serotonin Antagonists; Substance P; TRPA1 Cation Channel; TRPC Cation Channels

2017
Lateral hypothalamic-induced alpha-adrenoceptor modulation occurs in a model of inflammatory pain in rats.
    Biological research for nursing, 2009, Volume: 10, Issue:4

    Topics: Adrenergic alpha-Antagonists; Animals; Carbachol; Cholinergic Agonists; Disease Models, Animal; Female; Hypothalamic Area, Lateral; Inflammation; Isothiocyanates; Nociceptors; Nursing Research; Pain; Rats; Rats, Sprague-Dawley; Reaction Time; Receptors, Adrenergic, alpha; Tarsus, Animal; Yohimbine

2009
Inhibition of TRPA1 channel activity in sensory neurons by the glial cell line-derived neurotrophic factor family member, artemin.
    Molecular pain, 2011, May-27, Volume: 7

    Topics: Animals; Ankyrins; Behavior, Animal; Calcium Channels; Formaldehyde; Ganglia, Spinal; Glial Cell Line-Derived Neurotrophic Factor; Glial Cell Line-Derived Neurotrophic Factor Receptors; Ion Channel Gating; Isothiocyanates; Male; Nerve Tissue Proteins; Nociceptors; Pain; Protein Transport; Rats; Rats, Sprague-Dawley; Sensory Receptor Cells; Time Factors; TRPA1 Cation Channel; TRPC Cation Channels

2011
Etodolac blocks the allyl isothiocyanate-induced response in mouse sensory neurons by selective TRPA1 activation.
    Pharmacology, 2012, Volume: 90, Issue:1-2

    Topics: Analgesics, Non-Narcotic; Animals; Behavior, Animal; Calcium; Cells, Cultured; CHO Cells; Cricetinae; Cricetulus; Cyclooxygenase 2 Inhibitors; Etodolac; Ganglia, Spinal; HEK293 Cells; Humans; Isothiocyanates; Male; Mice; Pain; Sensory Receptor Cells; Transient Receptor Potential Channels; TRPA1 Cation Channel

2012
Effects of acute stressors on itch- and pain-related behaviors in rats.
    Pain, 2012, Volume: 153, Issue:9

    Topics: Animals; Behavior, Animal; Grooming; Injections, Intradermal; Irritants; Isothiocyanates; Male; Naltrexone; Narcotic Antagonists; Nociception; Pain; Pruritus; Rats; Rats, Sprague-Dawley; Serotonin; Stress, Psychological

2012
Sensitization of TRPA1 by PAR2 contributes to the sensation of inflammatory pain.
    The Journal of clinical investigation, 2007, Volume: 117, Issue:7

    Topics: Acrolein; Animals; Ankyrins; Behavior, Animal; Calcium Channels; Cell Line; Electrophysiology; Enzyme Activation; Ganglia, Spinal; Gene Expression Regulation; Humans; Inflammation; Isothiocyanates; Male; Nerve Tissue Proteins; Pain; Patch-Clamp Techniques; Phosphatidylinositol 4,5-Diphosphate; Protein Kinase C; Rats; Rats, Sprague-Dawley; Receptor, PAR-2; Transient Receptor Potential Channels; TRPA1 Cation Channel; TRPC Cation Channels; Type C Phospholipases

2007
Astroglial glutamate-glutamine shuttle is involved in central sensitization of nociceptive neurons in rat medullary dorsal horn.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2007, Aug-22, Volume: 27, Issue:34

    Topics: Action Potentials; Analysis of Variance; Animals; Dental Pulp; Drug Interactions; Glutamine; Isothiocyanates; Male; Methionine Sulfoximine; Neurons, Afferent; Nociceptors; Pain; Pain Threshold; Physical Stimulation; Rats; Rats, Sprague-Dawley; Trigeminal Caudal Nucleus

2007
Pronociceptive response elicited by TRPA1 receptor activation in mice.
    Neuroscience, 2008, Mar-18, Volume: 152, Issue:2

    Topics: Analgesics; Anilides; Animals; Behavior, Animal; Capsaicin; Cinnamates; Dipeptides; Dose-Response Relationship, Drug; Drug Interactions; Indoles; Isothiocyanates; Male; Mice; Pain; Pain Measurement; Ruthenium Red; Time Factors; Transient Receptor Potential Channels; TRPA1 Cation Channel

2008
Phospholipase C and protein kinase A mediate bradykinin sensitization of TRPA1: a molecular mechanism of inflammatory pain.
    Brain : a journal of neurology, 2008, Volume: 131, Issue:Pt 5

    Topics: Animals; Ankyrins; Bradykinin; Calcium Channels; Cells, Cultured; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Drug Synergism; Ganglia, Spinal; Humans; Inflammation; Isothiocyanates; Male; Pain; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Signal Transduction; TRPA1 Cation Channel; TRPC Cation Channels; Type C Phospholipases

2008