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alloxan and Tauopathies

alloxan has been researched along with Tauopathies in 1 studies

Alloxan: Acidic compound formed by oxidation of URIC ACID. It is isolated as an efflorescent crystalline hydrate.
alloxan : A member of the class of pyrimidones, the structure of which is that of perhydropyrimidine substituted at C-2, -4, -5 and -6 by oxo groups.

Tauopathies: Neurodegenerative disorders involving deposition of abnormal tau protein isoforms (TAU PROTEINS) in neurons and glial cells in the brain. Pathological aggregations of tau proteins are associated with mutation of the tau gene on chromosome 17 in patients with ALZHEIMER DISEASE; DEMENTIA; PARKINSONIAN DISORDERS; progressive supranuclear palsy (SUPRANUCLEAR PALSY, PROGRESSIVE); and corticobasal degeneration.

Research Excerpts

ExcerptRelevanceReference
"Alloxan treatment reduced HSP90 levels and promoted proteasomal degradation of tau, c-Jun N-amino terminal kinase, and histone deacetylase (HDAC) 6."1.38Adaptive responses to alloxan-induced mild oxidative stress ameliorate certain tauopathy phenotypes. ( Kimura, T; Maeda, S; Mizoroki, T; Murayama, M; Sahara, N; Soeda, Y; Takashima, A; Yamashita, S; Yoshiike, Y, 2012)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Yoshiike, Y1
Yamashita, S1
Mizoroki, T1
Maeda, S1
Murayama, M1
Kimura, T1
Sahara, N1
Soeda, Y1
Takashima, A1

Other Studies

1 other study available for alloxan and Tauopathies

ArticleYear
Adaptive responses to alloxan-induced mild oxidative stress ameliorate certain tauopathy phenotypes.
    Aging cell, 2012, Volume: 11, Issue:1

    Topics: Acetylation; Adaptation, Physiological; Aging; Alloxan; Animals; Disease Models, Animal; Female; His

2012