alloxan has been researched along with Pregnancy in Diabetes in 25 studies
Alloxan: Acidic compound formed by oxidation of URIC ACID. It is isolated as an efflorescent crystalline hydrate.
alloxan : A member of the class of pyrimidones, the structure of which is that of perhydropyrimidine substituted at C-2, -4, -5 and -6 by oxo groups.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Alloxan was used to induce diabetes (DWT, DTG, DKO) in female mice before pregnancy and, noninjected mice served as controls (NWT, NTG, NKO)." | 3.74 | Maternal blood glucose levels determine the severity of diabetic embryopathy in mice with different expression of copper-zinc superoxide dismutase (CuZnSOD). ( Eriksson, UJ; Wentzel, P; Zabihi, S, 2008) |
| "25 female sheep of the Texel breed were made hyperglycaemic by administration of alloxan monohydrate (ALX) in early pregnancy and 15 ewes served as controls." | 3.67 | Alloxan-induced diabetes mellitus in pregnant sheep and chronic fetal catheterization. ( Eskes, TK; Jongsma, HW; Lips, JP, 1988) |
| "To investigate whether maternal or fetal glucocorticoid secretion is altered during pregnancy complicated by diabetes mellitus, in vitro production of corticosterone (B) and cortisol (F) was measured on day 28 of gestation in rabbits made alloxan diabetic prior to pregnancy." | 3.66 | Maternal and fetal adrenocortical function in the diabetic rabbit. ( Beck, RR; Guleff, PS, 1981) |
| "Women with type 1 diabetes are subfertile." | 1.36 | Maternal diabetes impairs gastrulation and insulin and IGF-I receptor expression in rabbit blastocysts. ( Fischer, B; Fischer, S; Navarrete Santos, A; Ramin, N; Schindler, M; Schmidt, T; Thieme, R, 2010) |
| "We aimed to characterize the enamel hypoplasia in Wistar rats born to alloxan-induced diabetes mellitus rats." | 1.32 | Enamel hypoplasia in a litter of rats with alloxan-induced diabetes mellitus. ( Foss, MC; Peres, LC; Silva-Sousa, YT, 2003) |
| "Enamel hypoplasia is the most common developmental defect of human teeth that may be seen in deciduous teeth of babies born to diabetic women." | 1.32 | Are there structural alterations in the enamel organ of offspring of rats with alloxan-induced diabetes mellitus? ( Foss, MC; Peres, LC; Silva-Sousa, YT, 2003) |
| "Other evidence suggests that skeletal deformities may be due to hyperinsulinism in the foetuses of diabetic mothers." | 1.26 | Embryonic malformations in rats, resulting from maternal diabetes: preliminary observations. ( Deuchar, EM, 1977) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 14 (56.00) | 18.7374 |
| 1990's | 2 (8.00) | 18.2507 |
| 2000's | 4 (16.00) | 29.6817 |
| 2010's | 4 (16.00) | 24.3611 |
| 2020's | 1 (4.00) | 2.80 |
| Authors | Studies |
|---|---|
| Schindler, M | 5 |
| Dannenberger, D | 1 |
| Nuernberg, G | 1 |
| Pendzialek, M | 3 |
| Grybel, K | 1 |
| Seeling, T | 2 |
| Navarrete Santos, A | 5 |
| Grybel, KJ | 1 |
| Gürke, J | 2 |
| Fischer, B | 4 |
| Plösch, T | 1 |
| Seyring, S | 1 |
| Haucke, E | 1 |
| Knelangen, JM | 1 |
| Santos, AN | 1 |
| Ramin, N | 2 |
| Thieme, R | 2 |
| Fischer, S | 2 |
| Schmidt, T | 1 |
| Mühleck, B | 1 |
| Silva-Sousa, YT | 2 |
| Peres, LC | 2 |
| Foss, MC | 2 |
| BARASHNEV, IuI | 1 |
| Ettarh, RR | 1 |
| Arikawe, AP | 1 |
| Zabihi, S | 1 |
| Wentzel, P | 1 |
| Eriksson, UJ | 2 |
| Farrell, PM | 1 |
| Engle, MJ | 1 |
| Frantz, ID | 2 |
| Goldman, AS | 1 |
| Kalkhoff, R | 1 |
| Kemnitz, JW | 1 |
| Perelman, R | 1 |
| Stern, JS | 1 |
| Susa, JB | 1 |
| Sosenko, IR | 1 |
| Lawson, EE | 1 |
| Demottaz, V | 1 |
| Sapronova, AIa | 1 |
| Mitskevich, MS | 1 |
| Guleff, PS | 1 |
| Beck, RR | 1 |
| Martin, RJ | 1 |
| Makula, A | 1 |
| Kasser, TR | 1 |
| Ramsay, TG | 1 |
| White, ME | 1 |
| Wolverton, CK | 1 |
| Deuchar, EM | 1 |
| Guerra, MD | 1 |
| Peters, VM | 1 |
| Abdel-Rahman, MS | 1 |
| Elrakhawy, FI | 1 |
| Iskander, FA | 1 |
| Diamond, MP | 1 |
| Moley, KH | 1 |
| Pellicer, A | 1 |
| Vaughn, WK | 1 |
| DeCherney, AH | 1 |
| Lips, JP | 1 |
| Jongsma, HW | 1 |
| Eskes, TK | 1 |
| Goldner, MG | 1 |
| Spergel, G | 1 |
| Sisson, JA | 1 |
| Plotz, EJ | 1 |
| Jadick, PF | 1 |
| Althoff, J | 1 |
| Mohr, U | 1 |
| Pielsticker, K | 1 |
| Zimmer, F | 1 |
2 reviews available for alloxan and Pregnancy in Diabetes
| Article | Year |
|---|---|
Congenital malformations in diabetic animal models--a review.
Topics: Alloxan; Animals; Chromosome Aberrations; Congenital Abnormalities; Copper; Cricetinae; Diabetes Mel | 1984 |
On the transmission of alloxan diabetes and other diabetogenic influences.
Topics: Alloxan; Animals; Diabetes Mellitus; Diabetes Mellitus, Experimental; Female; Genes, Regulator; Huma | 1972 |
23 other studies available for alloxan and Pregnancy in Diabetes
| Article | Year |
|---|---|
Embryonic fatty acid metabolism in diabetic pregnancy: the difference between embryoblasts and trophoblasts.
Topics: Alloxan; Animals; Blastocyst; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Embryo, Ma | 2020 |
Adiponectin stimulates lipid metabolism via AMPK in rabbit blastocysts.
Topics: Acetyl-CoA Carboxylase; Adiponectin; Alloxan; AMP-Activated Protein Kinases; Animals; Blastocyst; Ca | 2017 |
Maternal diabetes leads to unphysiological high lipid accumulation in rabbit preimplantation embryos.
Topics: Alloxan; Animals; Blastocyst; Blood Glucose; Diabetes Mellitus, Type 1; Disease Models, Animal; Fatt | 2014 |
Maternal diabetes impairs gastrulation and insulin and IGF-I receptor expression in rabbit blastocysts.
Topics: Alloxan; Animals; Apoptosis; Blastocyst; Blood Glucose; Diabetes Mellitus, Experimental; Diabetes Me | 2010 |
Insulin growth factor adjustment in preimplantation rabbit blastocysts and uterine tissues in response to maternal type 1 diabetes.
Topics: Alloxan; Animals; Blastocyst; Cell Differentiation; Diabetes Mellitus, Experimental; Diabetes Mellit | 2012 |
Enamel hypoplasia in a litter of rats with alloxan-induced diabetes mellitus.
Topics: Alloxan; Animals; Blood Glucose; Dental Enamel Hypoplasia; Diabetes Mellitus, Experimental; Disease | 2003 |
[DISORDERS OF FETAL BRAIN DEVELOPMENT IN MATERNAL ALLOXAN DIABETES].
Topics: Alloxan; Animals; Brain; Brain Diseases; Congenital Abnormalities; Diabetes Mellitus, Experimental; | 1964 |
Are there structural alterations in the enamel organ of offspring of rats with alloxan-induced diabetes mellitus?
Topics: Alloxan; Ameloblasts; Amelogenesis; Animals; Blood Glucose; Cell Nucleus; Cell Size; Dental Enamel; | 2003 |
Effects of diabetes and insulin resistance in pregnant rats on ex vivo vascular reaction to magnesium.
Topics: Alloxan; Animals; Aorta; Blood Glucose; Diabetes Mellitus, Experimental; Female; In Vitro Techniques | 2004 |
Maternal blood glucose levels determine the severity of diabetic embryopathy in mice with different expression of copper-zinc superoxide dismutase (CuZnSOD).
Topics: Alloxan; Animals; Blood Glucose; Congenital Abnormalities; Diabetes Mellitus, Experimental; Female; | 2008 |
Complications of pregnancy and fetal development.
Topics: Alloxan; Animals; Congenital Abnormalities; Cricetinae; Cricetulus; Diabetes Mellitus, Experimental; | 1982 |
Functional delay in lung maturation in fetuses of diabetic rabbits.
Topics: Alloxan; Animals; Diabetes Mellitus, Experimental; Female; Lung; Lung Volume Measurements; Pregnancy | 1980 |
[Effect of removal of the hypothalamus and pituitary gland from rat fetuses on the development of pancreatic B-cell function].
Topics: Alloxan; Animals; Female; Hypophysectomy; Hypothalamus; Insulin; Insulin Secretion; Islets of Langer | 1981 |
Maternal and fetal adrenocortical function in the diabetic rabbit.
Topics: Adrenal Cortex; Alloxan; Animals; Corticosterone; Diabetes Mellitus, Experimental; Female; Fetal Blo | 1981 |
Placental metabolism and enzyme activities in diabetic pigs.
Topics: Alanine; Alanine Transaminase; Alloxan; Animals; Aspartate Aminotransferases; Diabetes Mellitus, Exp | 1980 |
The onset of maternal diabetes in swine induces alterations in the development of the fetal preadipocyte.
Topics: Adipocytes; Alloxan; Animals; Cell Differentiation; Cell Division; Cells, Cultured; Female; Fetus; G | 1995 |
Embryonic malformations in rats, resulting from maternal diabetes: preliminary observations.
Topics: Abnormalities, Multiple; Alloxan; Animals; Congenital Abnormalities; Diabetes Mellitus, Experimental | 1977 |
[Fetal macrosomy in alloxanized rats (author's transl)].
Topics: Alloxan; Animals; Body Weight; Diabetes Mellitus, Experimental; Female; Fetal Diseases; Insulin; Isl | 1979 |
Endocrine pancreas in the postnatal offspring of alloxan diabetic rats.
Topics: Alloxan; Animals; Animals, Newborn; Blood Glucose; Diabetes Mellitus, Experimental; Female; Fertilit | 1992 |
Effects of streptozotocin- and alloxan-induced diabetes mellitus on mouse follicular and early embryo development.
Topics: Alloxan; Animals; Diabetes Mellitus, Experimental; Embryonic and Fetal Development; Female; Insulin; | 1989 |
Alloxan-induced diabetes mellitus in pregnant sheep and chronic fetal catheterization.
Topics: Alloxan; Animals; Birth Weight; Blood Gas Analysis; Blood Glucose; Catheterization; Diabetes Mellitu | 1988 |
Maternal and fetal plasma lipids in alloxan diabetic and nondiabetic rabbits fed a peanut oil-cholesterol diet.
Topics: Alloxan; Animals; Cholesterol; Cholesterol, Dietary; Diabetes Mellitus, Experimental; Dietary Fats; | 1968 |
[Experimental studies of pregnancy toxemia problems in alloxan diabetic rats].
Topics: Abortion, Spontaneous; Alloxan; Amniotic Fluid; Animals; Blood Glucose; Body Weight; Diabetes Mellit | 1968 |