alloxan has been researched along with Obesity in 15 studies
Alloxan: Acidic compound formed by oxidation of URIC ACID. It is isolated as an efflorescent crystalline hydrate.
alloxan : A member of the class of pyrimidones, the structure of which is that of perhydropyrimidine substituted at C-2, -4, -5 and -6 by oxo groups.
Obesity: A status with BODY WEIGHT that is grossly above the recommended standards, usually due to accumulation of excess FATS in the body. The standards may vary with age, sex, genetic or cultural background. In the BODY MASS INDEX, a BMI greater than 30.0 kg/m2 is considered obese, and a BMI greater than 40.0 kg/m2 is considered morbidly obese (MORBID OBESITY).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Carnitine deficiency and impaired glucose tolerance (IGT) exacerbate liver steatosis." | 8.12 | High-fat diet-induced nonalcoholic steatohepatitis is accelerated by low carnitine and impaired glucose tolerance in novel murine models. ( Matsuura, T; Mekada, K; Nakamura, SI; Ozaki, K; Terayama, Y, 2022) |
| "Carnitine deficiency and impaired glucose tolerance (IGT) exacerbate liver steatosis." | 4.12 | High-fat diet-induced nonalcoholic steatohepatitis is accelerated by low carnitine and impaired glucose tolerance in novel murine models. ( Matsuura, T; Mekada, K; Nakamura, SI; Ozaki, K; Terayama, Y, 2022) |
| "Nonalcoholic fatty liver disease (NAFLD) occurs in approximately 80% of cases of type 2 diabetes mellitus (T2DM)." | 1.42 | Effects of fenugreek, Nigella, and termis seeds in nonalcoholic fatty liver in obese diabetic albino rats. ( Mohamed, KM; Mohamed, WS; Mostafa, AM; Serwah, AH, 2015) |
| "Alloxan-treated, Obese and non-obese/SHR manifested gross and microscopic degenerative changes suggesting acceleration of the normal aging process." | 1.27 | Resistance of obese and non-obese, spontaneously hypertensive rats to alloxan-induced diabetes. ( Mc Murtry, JP; Wexler, BC, 1983) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (66.67) | 18.7374 |
| 1990's | 2 (13.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (13.33) | 24.3611 |
| 2020's | 1 (6.67) | 2.80 |
| Authors | Studies |
|---|---|
| Terayama, Y | 1 |
| Nakamura, SI | 1 |
| Mekada, K | 1 |
| Matsuura, T | 1 |
| Ozaki, K | 1 |
| Mohamed, WS | 1 |
| Mostafa, AM | 1 |
| Mohamed, KM | 1 |
| Serwah, AH | 1 |
| Sladek, CD | 1 |
| Stevens, W | 1 |
| Song, Z | 1 |
| Johnson, GC | 1 |
| MacLean, PS | 1 |
| SOLOMON, J | 2 |
| MAYER, J | 3 |
| KUFTINEC, DM | 1 |
| Wexler, BC | 1 |
| Mc Murtry, JP | 1 |
| Mahler, RJ | 3 |
| Lazaris, IaA | 1 |
| Kasatkin, IuN | 1 |
| Gol'dberg, RS | 1 |
| Smirnova, LK | 1 |
| Angel, I | 1 |
| Hauger, RL | 1 |
| Giblin, BA | 1 |
| Paul, SM | 1 |
| Sekiguchi, F | 1 |
| Ishibashi, K | 1 |
| Kawamoto, Y | 1 |
| Ino, T | 1 |
| Gunnarsson, R | 1 |
| Hellerström, C | 1 |
| Bulkley, RJ | 1 |
| Szabo, O | 1 |
| Townley, RG | 1 |
| Daley, D | 1 |
| Selenke, W | 1 |
1 review available for alloxan and Obesity
| Article | Year |
|---|---|
The relationship between the hyperplastic pancreatic islet and insulin insensitivity in obesity.
Topics: Adipose Tissue; Alloxan; Animals; Glucagon; Glucose; Humans; Hyperplasia; Insulin; Insulin Resistanc | 1981 |
14 other studies available for alloxan and Obesity
| Article | Year |
|---|---|
High-fat diet-induced nonalcoholic steatohepatitis is accelerated by low carnitine and impaired glucose tolerance in novel murine models.
Topics: Alloxan; Animals; Carcinogenesis; Carnitine; Diet, High-Fat; Disease Models, Animal; Glucose Intoler | 2022 |
Effects of fenugreek, Nigella, and termis seeds in nonalcoholic fatty liver in obese diabetic albino rats.
Topics: Adipose Tissue; Alloxan; Analysis of Variance; Animals; Diabetes Mellitus, Experimental; Disease Mod | 2015 |
The "metabolic sensor" function of rat supraoptic oxytocin and vasopressin neurons is attenuated during lactation but not in diet-induced obesity.
Topics: Alloxan; Animals; Dehydration; Diet, High-Fat; Dietary Fats; Enzyme Inhibitors; Female; Glucokinase; | 2016 |
Effect of alloxan on obese hyperglycaemic mice.
Topics: Alloxan; Animals; Hyperglycemia; Mice; Mice, Obese; Obesity | 1962 |
EXTREME SENSITIVITY OF OBESE HYPERGLYCEMIC MICE TO CAFFEINE AND COFFEE.
Topics: Alloxan; Animals; Blood Glucose; Caffeine; Coffee; Glucose Tolerance Test; Hyperglycemia; Insulin; M | 1964 |
Resistance of obese and non-obese, spontaneously hypertensive rats to alloxan-induced diabetes.
Topics: Adrenal Cortex; Alloxan; Animals; Blood Glucose; Blood Pressure; Body Weight; Diabetes Mellitus, Exp | 1983 |
[Role of the endocrine function of the islands of Langerhans in the mechanism of development of hypothalamic obesity].
Topics: Alloxan; Animals; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Energy Intake; Female | 1976 |
Regulation of the anorectic drug recognition site during glucoprivic feeding.
Topics: Alloxan; Animals; Blood Glucose; Cerebral Ventricles; Deoxyglucose; Feeding Behavior; Glucose; Hypot | 1992 |
[Diabetic peculiarity of the ALS-Ay and ALR-Ay strains].
Topics: Alloxan; Animals; Diabetes Mellitus, Experimental; Disease Models, Animal; Female; Glucose Tolerance | 1991 |
The hyperplastic pancreatic islet as the cause of insulin resistance in obesity.
Topics: Alloxan; Animals; Blood Glucose; Diet; Humans; Hyperplasia; Insulin; Insulin Resistance; Islets of L | 1974 |
Acute effects of alloxan on the metabolism and insulin secretion of the pancreatic B-cell.
Topics: Alloxan; Anaerobiosis; Animals; Carbon Radioisotopes; Citrates; Female; Genotype; Glucose; Glycolysi | 1973 |
Effect of a low dose of alloxan on blood glucose, islet beta cell granulation, body weight, and insulin resistance of ob/ob mice.
Topics: Alloxan; Animals; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Fasting; Female; Gluc | 1974 |
Amelioration of insulin resistance in obese mice.
Topics: Alloxan; Animals; Blood Glucose; Body Weight; Fasting; Fatty Acids, Nonesterified; Hyperplasia; Inje | 1971 |
The effect of agents used in the treatment of bronchial asthma on carbohydrate metabolism and histamine sensitivity after beta-adrenergic blockade.
Topics: Adenine Nucleotides; Adrenal Cortex Hormones; Adrenalectomy; Alloxan; Aminophylline; Animals; Antige | 1970 |