alloxan has been researched along with Malaria in 9 studies
Alloxan: Acidic compound formed by oxidation of URIC ACID. It is isolated as an efflorescent crystalline hydrate.
alloxan : A member of the class of pyrimidones, the structure of which is that of perhydropyrimidine substituted at C-2, -4, -5 and -6 by oxo groups.
Malaria: A protozoan disease caused in humans by four species of the PLASMODIUM genus: PLASMODIUM FALCIPARUM; PLASMODIUM VIVAX; PLASMODIUM OVALE; and PLASMODIUM MALARIAE; and transmitted by the bite of an infected female mosquito of the genus ANOPHELES. Malaria is endemic in parts of Asia, Africa, Central and South America, Oceania, and certain Caribbean islands. It is characterized by extreme exhaustion associated with paroxysms of high FEVER; SWEATING; shaking CHILLS; and ANEMIA. Malaria in ANIMALS is caused by other species of plasmodia.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Three hours after iv administration of alloxan and 5,6-diamino-2,4-dihydroxy-pyrimidine to mice infected with chloroquine-sensitive (CS) and chloroquine-resistant (CR) strains of Plasmodium berghei, the 2 compounds showed remarkable antimalarial actions." | 7.67 | [Antimalarial action of alloxan and 5,6-diamino-2,4-dihydroxy-pyrimidine in Plasmodium berghei]. ( Chang, HL; Huang, ZY; Wang, JJ; Wu, KY, 1989) |
| "The in vivo antimalarial and antidiabetic activity of extract of Camellia sinensis (ECS) in alloxan-induced diabetic and Plasmodium berghei-infected mice were investigated." | 4.02 | Ethanolic extract of Camellia sinensise licited hypoglycemic but lacked antimalarial properties in Plasmodium berghei-infected diabetic mice. ( Ademowo, OG; Adisa, RA; Akinwunmi, MT; Aroyeun, SO, 2021) |
| "Three hours after iv administration of alloxan and 5,6-diamino-2,4-dihydroxy-pyrimidine to mice infected with chloroquine-sensitive (CS) and chloroquine-resistant (CR) strains of Plasmodium berghei, the 2 compounds showed remarkable antimalarial actions." | 3.67 | [Antimalarial action of alloxan and 5,6-diamino-2,4-dihydroxy-pyrimidine in Plasmodium berghei]. ( Chang, HL; Huang, ZY; Wang, JJ; Wu, KY, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (88.89) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (11.11) | 2.80 |
| Authors | Studies |
|---|---|
| Akinwunmi, MT | 1 |
| Adisa, RA | 1 |
| Aroyeun, SO | 1 |
| Ademowo, OG | 1 |
| Cox, FE | 3 |
| Millott, SM | 1 |
| Clark, IA | 2 |
| Hunt, NH | 1 |
| Huang, ZY | 1 |
| Chang, HL | 1 |
| Wu, KY | 1 |
| Wang, JJ | 1 |
| Cowden, WB | 1 |
| Chaudhri, G | 1 |
| Cenedella, RJ | 1 |
| Saxe, LH | 1 |
| Pollack, S | 1 |
| George, JN | 1 |
| Crosby, WH | 1 |
9 other studies available for alloxan and Malaria
| Article | Year |
|---|---|
Ethanolic extract of Camellia sinensise licited hypoglycemic but lacked antimalarial properties in Plasmodium berghei-infected diabetic mice.
Topics: Alloxan; Animals; Antimalarials; Camellia; Diabetes Mellitus, Experimental; Ethanol; Hypoglycemic Ag | 2021 |
Differential susceptibility of rodent malaria parasites to nonspecific immunity.
Topics: Alloxan; Animals; Disease Susceptibility; Erythrocytes; Female; Immunity, Innate; Malaria; Mice; Pla | 1983 |
The importance of parasite load in the killing of Plasmodium vinckei in mice treated with Corynebacterium parvum or alloxan monohydrate.
Topics: Alloxan; Animals; Erythrocytes; Immunity, Innate; Malaria; Mice; Propionibacterium acnes | 1984 |
Evidence for reactive oxygen intermediates causing hemolysis and parasite death in malaria.
Topics: Alloxan; Animals; Deferoxamine; Erythrocytes; Female; Free Radicals; Hemolysis; Hydrogen Peroxide; M | 1983 |
Oxidant killing of the malaria parasites.
Topics: Alloxan; Animals; Free Radicals; Malaria; Mice; Oxygen | 1983 |
[Antimalarial action of alloxan and 5,6-diamino-2,4-dihydroxy-pyrimidine in Plasmodium berghei].
Topics: Alloxan; Animals; Antimalarials; Female; Glutathione Reductase; Hemolysis; Malaria; Mice; Plasmodium | 1989 |
Possible roles for oxidants, through tumor necrosis factor, in malarial anemia.
Topics: Alloxan; Animals; Antioxidants; Cells, Cultured; Deferoxamine; Hydrogen Peroxide; Lipopolysaccharide | 1989 |
Partial reversal of the in vivo antimalarial activity of DDS against Plasmodium berghei by induced hyperglycemia.
Topics: Administration, Oral; Alloxan; Animals; Antimalarials; Blood Glucose; Dapsone; Erythrocytes; Glucose | 1971 |
Effect of agents simulating the abnormalities of the glucose-6-phosphate dehydrogenase-deficient red cell on Plasmodium berghei malaria.
Topics: Alloxan; Animals; Erythrocytes; Glutathione; Malaria; Methemoglobinemia; Mice; Nitrites; Phenylhydra | 1966 |