alloxan has been researched along with Innate Inflammatory Response in 27 studies
Alloxan: Acidic compound formed by oxidation of URIC ACID. It is isolated as an efflorescent crystalline hydrate.
alloxan : A member of the class of pyrimidones, the structure of which is that of perhydropyrimidine substituted at C-2, -4, -5 and -6 by oxo groups.
| Excerpt | Relevance | Reference |
|---|---|---|
| " This study investigated the role of genistein supplementation in inflammation and oxidative stress, which are related to NLRP3 inflammasome, NFκB and Nrf2 activation, during cutaneous wound healing in alloxan-induced diabetic mice." | 7.83 | Ameliorative effect of dietary genistein on diabetes induced hyper-inflammation and oxidative stress during early stage of wound healing in alloxan induced diabetic mice. ( Eo, H; Lee, HJ; Lim, Y, 2016) |
| "Alloxan-induced diabetes mellitus in rats was characterized by persistent increase in blood levels of corticosterone, while chronic granulomatous inflammation induced by silicon dioxide and its combination with alloxan-induced diabetes mellitus were associated with transient increase in blood corticosterone level followed by gradual development of hypoadrenocorticism." | 7.76 | Adrenocortical system response to induction of inflammation with silicon dioxide in rats with alloxan-induced diabetes mellitus. ( Kuznetsova, NV; Palchikova, NA; Selyatitskaya, VG; Shkurupiy, VA, 2010) |
| " The effect of alloxan diabetes and adrenalectomy on the acute inflammatory response was investigated in rats using the carrageenin-induced pleurisy model." | 7.67 | Effect of alloxan diabetes and adrenalectomy on carrageenin-induced pleurisy in the rat. ( Bechara, GH; Moraes, FR; Moraes, JR, 1987) |
| "Diabetic nephropathy is one of the major microvascular complications of diabetes mellitus which ultimately gives rise to cardiovascular diseases." | 5.46 | Small Molecule Inhibiting Nuclear Factor-kB Ameliorates Oxidative Stress and Suppresses Renal Inflammation in Early Stage of Alloxan-Induced Diabetic Nephropathy in Rat. ( Ahmed, S; Borgohain, MP; Choubey, A; Chowdhury, L; Kumar, S; Lahkar, M; Pant, R, 2017) |
| " This study investigated the role of genistein supplementation in inflammation and oxidative stress, which are related to NLRP3 inflammasome, NFκB and Nrf2 activation, during cutaneous wound healing in alloxan-induced diabetic mice." | 3.83 | Ameliorative effect of dietary genistein on diabetes induced hyper-inflammation and oxidative stress during early stage of wound healing in alloxan induced diabetic mice. ( Eo, H; Lee, HJ; Lim, Y, 2016) |
| "Dietary supplementation with CM fruits effectively prevents the development of diabetes mellitus, dyslipidemia and hepatic inflammation in alloxan-induced diabetes." | 3.80 | Biochemical and histopathological study of the anti-hyperglycemic and anti-hyperlipidemic effects of cornelian cherry (Cornus mas L.) in alloxan-induced diabetic rats. ( Asgary, S; Najafi, S; Rafieian-Kopaei, M; Sahebkar, A; Shamsi, F, 2014) |
| " To examine whether insulin influences the development of inflammation in the alveolar septa, diabetic male Wistar rats (alloxan, 42 mg/kg, i." | 3.77 | Insulin modulates inflammatory and repair responses to elastase-induced emphysema in diabetic rats. ( Capelozzi, VL; Castro, EO; Di Petta, A; Greco, KV; Lopes, FD; Martins, MA; Moreira, LF; Sannomiya, P, 2011) |
| "Alloxan-induced diabetes mellitus in rats was characterized by persistent increase in blood levels of corticosterone, while chronic granulomatous inflammation induced by silicon dioxide and its combination with alloxan-induced diabetes mellitus were associated with transient increase in blood corticosterone level followed by gradual development of hypoadrenocorticism." | 3.76 | Adrenocortical system response to induction of inflammation with silicon dioxide in rats with alloxan-induced diabetes mellitus. ( Kuznetsova, NV; Palchikova, NA; Selyatitskaya, VG; Shkurupiy, VA, 2010) |
| "Our findings show that alloxan diabetes induces downregulation of the skin allergic inflammatory response in rats, and this was correlated with reduction in local mast cell numbers and expression of extracellular matrix components." | 3.74 | Suppression of allergic inflammatory response in the skin of alloxan-diabetic rats: relationship with reduced local mast cell numbers. ( Barreto, EO; Campos, LV; de F Carvalho, V; e Silva, PM; Farias-Filho, FA; Florim, LT; Martins, MA; Pirmez, C; Savino, W, 2008) |
| " The effect of alloxan diabetes and adrenalectomy on the acute inflammatory response was investigated in rats using the carrageenin-induced pleurisy model." | 3.67 | Effect of alloxan diabetes and adrenalectomy on carrageenin-induced pleurisy in the rat. ( Bechara, GH; Moraes, FR; Moraes, JR, 1987) |
| "Arachidonic acid (AA) has potent anti-inflammatory actions and prevents the cytotoxic actions of alloxan and streptozotocin (STZ) against pancreatic β cells and thus, prevents the development of type 1 diabetes mellitus (induced by alloxan and STZ) and by virtue of its anti-inflammatory actions protects against the development of type 2 diabetes mellitus (DM) induced by STZ in experimental animals that are models of type 1 and type 2 DM in humans." | 1.72 | Syntaxin interacts with arachidonic acid to prevent diabetes mellitus. ( Das, UN, 2022) |
| "Inflammation is involved in diabetes-related vascular dysfunction." | 1.51 | Involvement of inducible nitric oxide synthase and estrogen receptor ESR2 (ERβ) in the vascular dysfunction in female type 1 diabetic rats. ( Akamine, EH; Carvalho, MHC; Ceravolo, GS; Costa, BP; Fortes, ZB; Santos, FF; Santos-Eichler, R; Sartoretto, SM, 2019) |
| "Diabetic nephropathy is one of the major microvascular complications of diabetes mellitus which ultimately gives rise to cardiovascular diseases." | 1.46 | Small Molecule Inhibiting Nuclear Factor-kB Ameliorates Oxidative Stress and Suppresses Renal Inflammation in Early Stage of Alloxan-Induced Diabetic Nephropathy in Rat. ( Ahmed, S; Borgohain, MP; Choubey, A; Chowdhury, L; Kumar, S; Lahkar, M; Pant, R, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (22.22) | 18.7374 |
| 1990's | 2 (7.41) | 18.2507 |
| 2000's | 2 (7.41) | 29.6817 |
| 2010's | 12 (44.44) | 24.3611 |
| 2020's | 5 (18.52) | 2.80 |
| Authors | Studies |
|---|---|
| Das, UN | 1 |
| Ojo, OA | 1 |
| Grant, S | 1 |
| Amanze, JC | 1 |
| Oni, AI | 1 |
| Ojo, AB | 1 |
| Elebiyo, TC | 1 |
| Obafemi, TO | 1 |
| Ayokunle, DI | 1 |
| Ogunlakin, AD | 1 |
| Wang, YL | 1 |
| Lin, SX | 1 |
| Wang, Y | 1 |
| Liang, T | 1 |
| Jiang, T | 1 |
| Liu, P | 1 |
| Li, XY | 1 |
| Lang, DQ | 1 |
| Liu, Q | 1 |
| Shen, CY | 1 |
| Zaib, M | 1 |
| Sharif, A | 1 |
| Akhtar, B | 1 |
| Khan, HM | 1 |
| Akhtar, MF | 1 |
| Hassan, W | 1 |
| Razzaq, F | 1 |
| Nawaz, S | 1 |
| Qaisar, N | 1 |
| Sartoretto, SM | 1 |
| Santos, FF | 1 |
| Costa, BP | 1 |
| Ceravolo, GS | 1 |
| Santos-Eichler, R | 1 |
| Carvalho, MHC | 1 |
| Fortes, ZB | 1 |
| Akamine, EH | 1 |
| de Azevedo Queiroz, ÍO | 1 |
| Gonçalves, LO | 1 |
| Takamiya, AS | 1 |
| Rezende, GC | 1 |
| Machado, T | 1 |
| Siveiri-Araujo, G | 1 |
| Ervolino, E | 1 |
| Oliveira, SHP | 1 |
| Gomes-Filho, JE | 1 |
| Carlos, D | 1 |
| Spiller, F | 1 |
| Souto, FO | 1 |
| Trevelin, SC | 1 |
| Borges, VF | 1 |
| de Freitas, A | 1 |
| Alves-Filho, JC | 1 |
| Silva, JS | 1 |
| Ryffel, B | 1 |
| Cunha, FQ | 1 |
| Asgary, S | 1 |
| Rafieian-Kopaei, M | 1 |
| Shamsi, F | 1 |
| Najafi, S | 1 |
| Sahebkar, A | 1 |
| Langoni Cassettari, L | 1 |
| Colli Rocha Dias, P | 1 |
| Natália Lucchesi, A | 1 |
| Ferraz de Arruda, M | 1 |
| Veruska Paiva Ortolan, E | 1 |
| Marques, ME | 1 |
| Spadella, CT | 1 |
| Fraga-Silva, TF | 1 |
| Marchetti, CM | 1 |
| Mimura, LA | 1 |
| Locachevic, GA | 1 |
| Golim, MA | 1 |
| Venturini, J | 1 |
| Arruda, MS | 1 |
| Zhao, Q | 1 |
| Li, J | 1 |
| Yan, J | 1 |
| Liu, S | 1 |
| Guo, Y | 1 |
| Chen, D | 1 |
| Luo, Q | 1 |
| Eo, H | 1 |
| Lee, HJ | 1 |
| Lim, Y | 1 |
| Borgohain, MP | 1 |
| Lahkar, M | 1 |
| Ahmed, S | 1 |
| Chowdhury, L | 1 |
| Kumar, S | 1 |
| Pant, R | 1 |
| Choubey, A | 1 |
| de F Carvalho, V | 1 |
| Campos, LV | 1 |
| Farias-Filho, FA | 1 |
| Florim, LT | 1 |
| Barreto, EO | 1 |
| Pirmez, C | 1 |
| Savino, W | 1 |
| Martins, MA | 3 |
| e Silva, PM | 1 |
| Pradhan, L | 1 |
| Cai, X | 1 |
| Wu, S | 1 |
| Andersen, ND | 1 |
| Martin, M | 1 |
| Malek, J | 1 |
| Guthrie, P | 1 |
| Veves, A | 1 |
| Logerfo, FW | 1 |
| Kuznetsova, NV | 1 |
| Palchikova, NA | 1 |
| Selyatitskaya, VG | 1 |
| Shkurupiy, VA | 1 |
| Gumieniczek, A | 1 |
| Komsta, L | 1 |
| Chehab, MR | 1 |
| Di Petta, A | 1 |
| Greco, KV | 1 |
| Castro, EO | 1 |
| Lopes, FD | 1 |
| Capelozzi, VL | 1 |
| Moreira, LF | 1 |
| Sannomiya, P | 1 |
| de Oliveira Barreto, E | 1 |
| de Frias Carvalho, V | 1 |
| Diaz, BL | 1 |
| Balduino, A | 1 |
| Cordeiro, RS | 1 |
| Rodrigues e Sílva, PM | 1 |
| MAYASHI, H | 1 |
| MIYOSHI, H | 1 |
| NITTA, R | 1 |
| UDAKA, K | 1 |
| Sandler, S | 1 |
| Andersson, A | 1 |
| Jean, T | 1 |
| Bodinier, MC | 1 |
| Gamian, E | 1 |
| Kochman, A | 1 |
| Rabczyński, J | 1 |
| Burczak, K | 1 |
| Fromer, CH | 1 |
| Klintworth, GK | 1 |
| Moraes, FR | 1 |
| Bechara, GH | 1 |
| Moraes, JR | 1 |
| Vegad, JL | 1 |
| Masada, A | 1 |
27 other studies available for alloxan and Innate Inflammatory Response
| Article | Year |
|---|---|
Syntaxin interacts with arachidonic acid to prevent diabetes mellitus.
Topics: Alloxan; Animals; Anti-Inflammatory Agents; Arachidonic Acid; Diabetes Mellitus, Type 2; Dinoproston | 2022 |
Annona muricata L. peel extract inhibits carbohydrate metabolizing enzymes and reduces pancreatic β-cells, inflammation, and apoptosis via upregulation of PI3K/AKT genes.
Topics: Alloxan; alpha-Amylases; alpha-Glucosidases; Animals; Annona; Apoptosis; Blood Glucose; Diabetes Mel | 2022 |
Topics: Alloxan; Animals; Antioxidants; Diabetes Mellitus, Experimental; Glutathione; Inflammation; Mice; Mi | 2023 |
Berberis lycium Royle. extracts attenuate inflammation and modulates hyperglycemia in alloxan induced diabetic rats.
Topics: Alloxan; alpha-Amylases; Animals; Antioxidants; Berberis; Blood Glucose; Diabetes Mellitus, Experime | 2020 |
Involvement of inducible nitric oxide synthase and estrogen receptor ESR2 (ERβ) in the vascular dysfunction in female type 1 diabetic rats.
Topics: Alloxan; Animals; Aorta; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Endothelium, Va | 2019 |
Hyperglycemic condition influence on mineral trioxide aggregate biocompatibility and biomineralization.
Topics: Alloxan; Aluminum Compounds; Animals; Biocompatible Materials; Biomineralization; Blood Glucose; Cal | 2020 |
Histamine h2 receptor signaling in the pathogenesis of sepsis: studies in a murine diabetes model.
Topics: Alloxan; Animals; Bacteremia; Cell Movement; Diabetes Mellitus, Experimental; Down-Regulation; Femal | 2013 |
Biochemical and histopathological study of the anti-hyperglycemic and anti-hyperlipidemic effects of cornelian cherry (Cornus mas L.) in alloxan-induced diabetic rats.
Topics: Alkaline Phosphatase; Alloxan; Animals; Anthocyanins; Blood Glucose; Chemical and Drug Induced Liver | 2014 |
Continuous electrical current and zinc sulphate administered by transdermal iontophoresis improves skin healing in diabetic rats induced by alloxan: morphological and ultrastructural analysis.
Topics: Administration, Cutaneous; Alloxan; Animals; Cell Proliferation; Collagen; Diabetes Mellitus, Experi | 2014 |
Relationship among Short and Long Term of Hypoinsulinemia-Hyperglycemia, Dermatophytosis, and Immunobiology of Mononuclear Phagocytes.
Topics: Alloxan; Animals; Bone Marrow; Cell Adhesion; Diabetes Mellitus; Humans; Hydrogen Peroxide; Hypergly | 2015 |
Lycium barbarum polysaccharides ameliorates renal injury and inflammatory reaction in alloxan-induced diabetic nephropathy rabbits.
Topics: Alloxan; Animals; Blood Glucose; Body Weight; Chemokine CCL2; Diabetic Nephropathies; Inflammation; | 2016 |
Ameliorative effect of dietary genistein on diabetes induced hyper-inflammation and oxidative stress during early stage of wound healing in alloxan induced diabetic mice.
Topics: Alloxan; Animals; Biomarkers; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Dietary S | 2016 |
Small Molecule Inhibiting Nuclear Factor-kB Ameliorates Oxidative Stress and Suppresses Renal Inflammation in Early Stage of Alloxan-Induced Diabetic Nephropathy in Rat.
Topics: Alloxan; Animals; Antioxidants; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Dose-Respon | 2017 |
Suppression of allergic inflammatory response in the skin of alloxan-diabetic rats: relationship with reduced local mast cell numbers.
Topics: Allergens; Alloxan; Aluminum Hydroxide; Animals; Diabetes Mellitus, Experimental; Down-Regulation; E | 2008 |
Gene expression of pro-inflammatory cytokines and neuropeptides in diabetic wound healing.
Topics: Alloxan; Animals; Cytokines; Diabetes Mellitus, Experimental; Disease Models, Animal; Inflammation; | 2011 |
Adrenocortical system response to induction of inflammation with silicon dioxide in rats with alloxan-induced diabetes mellitus.
Topics: Adrenal Cortex; Alloxan; Animals; Blood Glucose; Corticosterone; Diabetes Mellitus, Experimental; In | 2010 |
Effects of two oral antidiabetics, pioglitazone and repaglinide, on aconitase inactivation, inflammation and oxidative/nitrosative stress in tissues under alloxan-induced hyperglycemia.
Topics: Aconitate Hydratase; Administration, Oral; Alloxan; Animals; Blood Glucose; Body Weight; Carbamates; | 2011 |
Insulin modulates inflammatory and repair responses to elastase-induced emphysema in diabetic rats.
Topics: Alloxan; Animals; Blood Glucose; Cell Movement; Collagen; Comorbidity; Diabetes Mellitus, Experiment | 2011 |
Adoptive transfer of mast cells abolishes the inflammatory refractoriness to allergen in diabetic rats.
Topics: Adoptive Transfer; Allergens; Alloxan; Animals; Diabetes Mellitus, Experimental; Histamine Release; | 2003 |
Proteolytic mechanism in recurrence of Arthus-type inflammation by thiol compounds.
Topics: Alloxan; Cysteine; Glutathione; Hydrolases; Inflammation; Peptide Hydrolases; Proteolysis; Recurrenc | 1962 |
Survival of intrasplenically implanted islets in mice with experimental insulitis and hyperglycemia.
Topics: Alloxan; Animals; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Female; Graft Survival | 1982 |
Mediators involved in inflammation: effects of Daflon 500 mg on their release.
Topics: Alloxan; Animals; Anti-Inflammatory Agents; Blood Glucose; Diabetes Mellitus, Experimental; Diosmin; | 1994 |
[Biocompatibility testing and function of a pancreatic prosthesis consisting of viable pancreatic islets encapsulated in PVA macrocapsules].
Topics: Albumins; Alloxan; Animals; Biocompatible Materials; Capsules; Diabetes Mellitus, Experimental; Fema | 1999 |
An evaluation of the role of leukocytes in the pathogenesis of experimentally induced corneal vascularization.
Topics: Administration, Topical; Alloxan; Animals; Antigen-Antibody Complex; Cattle; Cautery; Cornea; Cornea | 1975 |
Effect of alloxan diabetes and adrenalectomy on carrageenin-induced pleurisy in the rat.
Topics: Acute-Phase Reaction; Adrenalectomy; Alloxan; Animals; Capillary Permeability; Carrageenan; Diabetes | 1987 |
Effect of alloxan monohydrate on increased vascular permeability in sheep.
Topics: Alloxan; Animals; Capillary Permeability; Cell Membrane Permeability; Female; Histamine Release; Inf | 1972 |
[Inhivition of inflammatory reactions by hyperglycemia].
Topics: Alloxan; Animals; Blood Glucose; Bradykinin; Dextrans; Glucose; Guinea Pigs; Hexoses; Histamine; Hyp | 1968 |