Page last updated: 2024-11-06

alloxan and Hypersensitivity

alloxan has been researched along with Hypersensitivity in 6 studies

Alloxan: Acidic compound formed by oxidation of URIC ACID. It is isolated as an efflorescent crystalline hydrate.
alloxan : A member of the class of pyrimidones, the structure of which is that of perhydropyrimidine substituted at C-2, -4, -5 and -6 by oxo groups.

Hypersensitivity: Altered reactivity to an antigen, which can result in pathologic reactions upon subsequent exposure to that particular antigen.

Research Excerpts

ExcerptRelevanceReference
"Our findings show that alloxan diabetes induces downregulation of the skin allergic inflammatory response in rats, and this was correlated with reduction in local mast cell numbers and expression of extracellular matrix components."3.74Suppression of allergic inflammatory response in the skin of alloxan-diabetic rats: relationship with reduced local mast cell numbers. ( Barreto, EO; Campos, LV; de F Carvalho, V; e Silva, PM; Farias-Filho, FA; Florim, LT; Martins, MA; Pirmez, C; Savino, W, 2008)
"The treatment with zopolrestat restored antigen-induced protein extravazation and mast cell degranulation in the pleural cavity of diabetic sensitized rats."1.33Aldose reductase inhibitor zopolrestat restores allergic hyporesponsiveness in alloxan-diabetic rats. ( Barreto, EO; Carvalho, VF; Cordeiro, RS; e Silva, PM; Fortes, ZB; Martins, MA; Serra, MF, 2006)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19904 (66.67)18.7374
1990's0 (0.00)18.2507
2000's2 (33.33)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
de F Carvalho, V1
Campos, LV1
Farias-Filho, FA1
Florim, LT1
Barreto, EO2
Pirmez, C1
Savino, W1
Martins, MA2
e Silva, PM2
CORNFORTH, JW1
LONG, DA1
THOMPSON, GE2
DEFALCO, RJ1
HELLMAN, B1
Carvalho, VF1
Serra, MF1
Cordeiro, RS1
Fortes, ZB1

Other Studies

6 other studies available for alloxan and Hypersensitivity

ArticleYear
Suppression of allergic inflammatory response in the skin of alloxan-diabetic rats: relationship with reduced local mast cell numbers.
    International archives of allergy and immunology, 2008, Volume: 147, Issue:3

    Topics: Allergens; Alloxan; Aluminum Hydroxide; Animals; Diabetes Mellitus, Experimental; Down-Regulation; E

2008
Influence of carbohydrate metabolism on bacterial allergy; its relation to cortisone desensitisation.
    Lancet (London, England), 1953, Jan-24, Volume: 1, Issue:6752

    Topics: Alloxan; Ascorbic Acid; Carbohydrate Metabolism; Carbohydrates; Cortisone; Desensitization, Immunolo

1953
Alloxan and hypersensitivity.
    Nature, 1961, May-27, Volume: 190

    Topics: Alloxan; Hypersensitivity; Immune System Diseases

1961
ALLOXAN AND HYPERSENSITIVITY. II. EFFECT OF ALLOXAN ON HYPERSENSITIVITY REACTIONS IN THE MOUSE, RAT, AND GUINEA PIG.
    The Cornell veterinarian, 1965, Volume: 55

    Topics: Alloxan; Anaphylaxis; Animals; Arthus Reaction; Encephalomyelitis; Encephalomyelitis, Autoimmune, Ex

1965
The effect of protracted administration of small doses of alloxan on the islets of langerhans in rats fed on diets rich and poor in carbohydrate.
    Acta Societatis Medicorum Upsaliensis, 1959, Volume: 64

    Topics: Alloxan; Animals; Carbohydrates; Diet; Hypersensitivity; Islands; Islets of Langerhans; Nutrition As

1959
Aldose reductase inhibitor zopolrestat restores allergic hyporesponsiveness in alloxan-diabetic rats.
    European journal of pharmacology, 2006, Nov-07, Volume: 549, Issue:1-3

    Topics: Aldehyde Reductase; Alloxan; Aluminum Hydroxide; Animals; Benzothiazoles; Cell Count; Cell Degranula

2006