Page last updated: 2024-11-06

alloxan and Hyperlipemia

alloxan has been researched along with Hyperlipemia in 18 studies

Alloxan: Acidic compound formed by oxidation of URIC ACID. It is isolated as an efflorescent crystalline hydrate.
alloxan : A member of the class of pyrimidones, the structure of which is that of perhydropyrimidine substituted at C-2, -4, -5 and -6 by oxo groups.

Research Excerpts

ExcerptRelevanceReference
"Alloxan diabetic mice were treated with EGCG."5.72(-)-Epigallocatechin gallate (EGCG) pharmacokinetics and molecular interactions towards amelioration of hyperglycemia, hyperlipidemia associated hepatorenal oxidative injury in alloxan induced diabetic mice. ( Adnan, M; Badraoui, R; Ben-Nasr, H; Chappard, D; El-Feki, A; Gargouri, M; Kausar, MA; Magné, C; Saeed, M; Siddiqui, AJ; Snoussi, M; Soussi, A, 2022)
"Alloxan-induced hyperglycemia was accompanied by activation of lipid peroxidation processes with different degree of their completeness depending on the age of experimental animals."3.73Age-related differences in the degree of lipid peroxidation and state of antioxidant protection under the influence of alloxan. ( Gvozdenko, TA; Yan'kova, VI, 2005)
"Alloxan diabetic mice were treated with EGCG."1.72(-)-Epigallocatechin gallate (EGCG) pharmacokinetics and molecular interactions towards amelioration of hyperglycemia, hyperlipidemia associated hepatorenal oxidative injury in alloxan induced diabetic mice. ( Adnan, M; Badraoui, R; Ben-Nasr, H; Chappard, D; El-Feki, A; Gargouri, M; Kausar, MA; Magné, C; Saeed, M; Siddiqui, AJ; Snoussi, M; Soussi, A, 2022)
"Alloxan was used to induce diabetes in male Watanabe heritable hyperlipidemic (WHHL) rabbits that were sacrificed 2 and 6 months after the induction of diabetes."1.33VEGF-A, VEGF-D, VEGF receptor-1, VEGF receptor-2, NF-kappaB, and RAGE in atherosclerotic lesions of diabetic Watanabe heritable hyperlipidemic rabbits. ( Ahtialansaari, T; Babu, M; Bhardwaj, S; Hakumaki, J; Herzig, KH; Kokina, I; Laakso, M; Laitinen, T; Roy, H; Uotila, S; Ylä-Herttuala, S, 2006)
"Postprandial dyslipidemia may be a major cause of atherosclerosis in diabetes."1.31Intestinal rather than hepatic microsomal triglyceride transfer protein as a cause of postprandial dyslipidemia in diabetes. ( Anderton, K; Bennett, A; Collins, P; Owens, D; Phillips, C; Tomkin, GH; White, D, 2002)
"Alloxan-diabetic rats were kept on an ordinary or 0."1.29[Changes in serum lipid and lipoproteins in alloxan-diabetic rats--studies for one year]. ( Arisue, K; Takeuchi, N; Uchida, K, 1994)

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19905 (27.78)18.7374
1990's2 (11.11)18.2507
2000's5 (27.78)29.6817
2010's3 (16.67)24.3611
2020's3 (16.67)2.80

Authors

AuthorsStudies
Soussi, A1
Gargouri, M1
Magné, C1
Ben-Nasr, H1
Kausar, MA1
Siddiqui, AJ1
Saeed, M1
Snoussi, M1
Adnan, M1
El-Feki, A1
Chappard, D1
Badraoui, R1
Umar, U1
Ahmed, S1
Iftikhar, A1
Iftikhar, M1
Majeed, W1
Liaqat, A1
Shahzad, S1
Abbas, M1
Mehmood, T1
Anwar, F1
Elseweidy, MM1
Elnagar, GM1
M Elsawy, M1
Ali, AA1
Zein, N1
El-Tantawy, WH1
Haleem, EN1
Kaimal, S1
Sujatha, KS1
George, S1
Volchegorskiĭ, IA1
Rassokhina, LM1
Miroshnichenko, IIu1
Pan, J1
Liu, G1
Liu, H1
Qiu, Z1
Chen, L1
Kameswararao, B1
Kesavulu, MM1
Apparao, C1
OHE, K1
TAGUCHI, K1
INOUE, T1
KATSURA, E1
COURTICE, FC2
MUNOZ-MARCUS, M2
GARLICK, DG1
el-Batran, SA1
el-Shenawy, SM1
Nofal, SM1
Abdel-Salam, OM1
Arbid, MS1
Yan'kova, VI1
Gvozdenko, TA1
Roy, H1
Bhardwaj, S1
Babu, M1
Kokina, I1
Uotila, S1
Ahtialansaari, T1
Laitinen, T1
Hakumaki, J1
Laakso, M1
Herzig, KH1
Ylä-Herttuala, S1
Smith, SL1
Novotný, M1
Nakakimura, H1
Mizuno, K1
Arisue, K1
Uchida, K1
Takeuchi, N1
Phillips, C1
Bennett, A1
Anderton, K1
Owens, D1
Collins, P1
White, D1
Tomkin, GH1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Impact of Bariatric Surgery on Circulating Inflammatory and Pro-vascular Progenitor Cell Populations.[NCT04132531]38 participants (Actual)Observational2018-05-01Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

18 other studies available for alloxan and Hyperlipemia

ArticleYear
(-)-Epigallocatechin gallate (EGCG) pharmacokinetics and molecular interactions towards amelioration of hyperglycemia, hyperlipidemia associated hepatorenal oxidative injury in alloxan induced diabetic mice.
    Chemico-biological interactions, 2022, Dec-01, Volume: 368

    Topics: Alloxan; Animals; Antioxidants; Blood Glucose; Catechin; Diabetes Mellitus, Experimental; Hyperglyce

2022
Phenolics Extracted from
    Molecules (Basel, Switzerland), 2023, Jul-17, Volume: 28, Issue:14

    Topics: Alloxan; Animals; bcl-2-Associated X Protein; Biomarkers; Blood Glucose; Caspase 3; Diabetes Mellitu

2023
Losartan and azelastine either alone or in combination as modulators for endothelial dysfunction and platelets activation in diabetic hyperlipidemic rats.
    The Journal of pharmacy and pharmacology, 2020, Volume: 72, Issue:12

    Topics: Alloxan; Angiotensin II Type 1 Receptor Blockers; Animals; Atherosclerosis; Blood Platelets; Diabete

2020
Therapeutic effects of stem cell on hyperglycemia, hyperlipidemia, and oxidative stress in alloxan-treated rats.
    Molecular and cellular biochemistry, 2014, Volume: 391, Issue:1-2

    Topics: Alloxan; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Female; Flow Cytometry; Glutathion

2014
Hypolipidaemic and antioxidant effects of fruits of Musa AAA (Chenkadali) in alloxan induced diabetic rats.
    Indian journal of experimental biology, 2010, Volume: 48, Issue:2

    Topics: Alanine Transaminase; Alloxan; Animals; Antioxidants; Cholesterol; Diabetes Mellitus, Experimental;

2010
[Antihypoxic effect of 3-hydroxypyridine and succinic acid derivatives and their nootropic action in alloxan diabetes].
    Eksperimental'naia i klinicheskaia farmakologiia, 2011, Volume: 74, Issue:12

    Topics: Alloxan; Animals; Conditioning, Classical; Diabetes Mellitus, Experimental; Diabetic Neuropathies; D

2011
[Effects of artemisia capillaris on blood glucose and lipid in mice].
    Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 1998, Volume: 21, Issue:8

    Topics: Alloxan; Animals; Artemisia; Blood Glucose; Cholesterol; Diabetes Mellitus, Experimental; Drugs, Chi

1998
Evaluation of antidiabetic effect of Momordica cymbalaria fruit in alloxan-diabetic rats.
    Fitoterapia, 2003, Volume: 74, Issue:1-2

    Topics: Alloxan; Animals; Blood Glucose; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Diabetes Mellitus,

2003
STUDIES ON THE TURNOVER OF LIPIDS IN ALLOXAN-DIABETIC RATS.
    Acta Scholae Medicinalis Universitatis in Kioto, 1964, Volume: 39

    Topics: Acetates; Alloxan; Animals; Carbon Isotopes; Cholesterol; Diabetes Mellitus, Experimental; Fatty Aci

1964
THE COMPOSITION OF THE PLASMA LIPOPROTEINS IN EXPERIMENTAL HYPERLIPAEMIA INDUCED BY TRITON WR-1339, CORTISONE, ALLOXAN AND HAEMORRHAGE IN RABBITS.
    Quarterly journal of experimental physiology and cognate medical sciences, 1964, Volume: 49

    Topics: Alloxan; Animals; Blood Proteins; Cholesterol; Cortisone; Hemorrhage; Hyperlipidemias; Lipoproteins;

1964
THE PERMEABILITY OF THE BLOOD CAPILLARIES OF THE LEG TO THE LIPOPROTEINS IN VARIOUS HYPERLIPAEMIC STATES IN THE RABBIT.
    Quarterly journal of experimental physiology and cognate medical sciences, 1964, Volume: 49

    Topics: Alloxan; Animals; Arteriosclerosis; Burns; Capillaries; Capillary Permeability; Cortisone; Hyperlipi

1964
Studies on the glycemic and lipidemic effect of monopril and losartan in normal and diabetic rats.
    Pharmacological research, 2004, Volume: 50, Issue:2

    Topics: Alloxan; Animals; Blood Glucose; Blood Proteins; Carbamates; Cholesterol, LDL; Diabetes Mellitus, Ex

2004
Age-related differences in the degree of lipid peroxidation and state of antioxidant protection under the influence of alloxan.
    Bulletin of experimental biology and medicine, 2005, Volume: 139, Issue:3

    Topics: Aging; Alloxan; Animals; Antioxidants; Diabetes Mellitus, Experimental; Hyperglycemia; Hyperlipidemi

2005
VEGF-A, VEGF-D, VEGF receptor-1, VEGF receptor-2, NF-kappaB, and RAGE in atherosclerotic lesions of diabetic Watanabe heritable hyperlipidemic rabbits.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2006, Volume: 20, Issue:12

    Topics: Alloxan; Animals; Atherosclerosis; Diabetes Mellitus, Experimental; Disease Models, Animal; Hyperlip

2006
Studies of hyperlipidemia in drug-induced diabetic rats by high-performance liquid chromatography.
    Journal of chromatography, 1980, Nov-14, Volume: 221, Issue:1

    Topics: Alloxan; Animals; Chromatography, High Pressure Liquid; Diabetes Mellitus, Experimental; Hyperlipide

1980
Studies on lipid peroxidation in biological systems. II. Hyperlipoperoxidemia in mice induced by alloxan.
    Chemical & pharmaceutical bulletin, 1980, Volume: 28, Issue:7

    Topics: Alloxan; Animals; Blood Glucose; Carbon Tetrachloride; Dose-Response Relationship, Drug; Hyperlipide

1980
[Changes in serum lipid and lipoproteins in alloxan-diabetic rats--studies for one year].
    Jikken dobutsu. Experimental animals, 1994, Volume: 43, Issue:2

    Topics: Alloxan; Animals; Blood Glucose; Cholesterol; Diabetes Mellitus, Experimental; Hyperlipidemias; Insu

1994
Intestinal rather than hepatic microsomal triglyceride transfer protein as a cause of postprandial dyslipidemia in diabetes.
    Metabolism: clinical and experimental, 2002, Volume: 51, Issue:7

    Topics: Alloxan; Animals; Apolipoprotein B-100; Apolipoprotein B-48; Apolipoproteins B; Carrier Proteins; Ch

2002