Page last updated: 2024-11-06

alloxan and Glucose Intolerance

alloxan has been researched along with Glucose Intolerance in 4 studies

Alloxan: Acidic compound formed by oxidation of URIC ACID. It is isolated as an efflorescent crystalline hydrate.
alloxan : A member of the class of pyrimidones, the structure of which is that of perhydropyrimidine substituted at C-2, -4, -5 and -6 by oxo groups.

Glucose Intolerance: A pathological state in which BLOOD GLUCOSE level is less than approximately 140 mg/100 ml of PLASMA at fasting, and above approximately 200 mg/100 ml plasma at 30-, 60-, or 90-minute during a GLUCOSE TOLERANCE TEST. This condition is seen frequently in DIABETES MELLITUS, but also occurs with other diseases and MALNUTRITION.

Research Excerpts

ExcerptRelevanceReference
"Carnitine deficiency and impaired glucose tolerance (IGT) exacerbate liver steatosis."8.12High-fat diet-induced nonalcoholic steatohepatitis is accelerated by low carnitine and impaired glucose tolerance in novel murine models. ( Matsuura, T; Mekada, K; Nakamura, SI; Ozaki, K; Terayama, Y, 2022)
"Alloxan treatment, however, does not alter lymph insulin kinetics, indicating that insulin resistance of Type 1 (insulin-dependent) diabetes mellitus reflects direct impairment at the cellular level."5.30Evidence for direct action of alloxan to induce insulin resistance at the cellular level. ( Ader, M; Bergman, RN; Richey, JM, 1998)
"Carnitine deficiency and impaired glucose tolerance (IGT) exacerbate liver steatosis."4.12High-fat diet-induced nonalcoholic steatohepatitis is accelerated by low carnitine and impaired glucose tolerance in novel murine models. ( Matsuura, T; Mekada, K; Nakamura, SI; Ozaki, K; Terayama, Y, 2022)
"Alloxan treatment, however, does not alter lymph insulin kinetics, indicating that insulin resistance of Type 1 (insulin-dependent) diabetes mellitus reflects direct impairment at the cellular level."1.30Evidence for direct action of alloxan to induce insulin resistance at the cellular level. ( Ader, M; Bergman, RN; Richey, JM, 1998)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (25.00)18.2507
2000's2 (50.00)29.6817
2010's0 (0.00)24.3611
2020's1 (25.00)2.80

Authors

AuthorsStudies
Terayama, Y1
Nakamura, SI1
Mekada, K1
Matsuura, T1
Ozaki, K1
Li, M1
Miyagawa, J1
Yamamoto, K1
Moriwaki, M1
Imagawa, A1
Iwahashi, H1
Yamagata, K1
Tochino, Y1
Hanafusa, T1
Matsuzawa, Y1
Salkovic-Petrisic, M1
Lackovic, Z1
Hoyer, S1
Riederer, P1
Ader, M1
Richey, JM1
Bergman, RN1

Other Studies

4 other studies available for alloxan and Glucose Intolerance

ArticleYear
High-fat diet-induced nonalcoholic steatohepatitis is accelerated by low carnitine and impaired glucose tolerance in novel murine models.
    Laboratory investigation; a journal of technical methods and pathology, 2022, Volume: 102, Issue:6

    Topics: Alloxan; Animals; Carcinogenesis; Carnitine; Diet, High-Fat; Disease Models, Animal; Glucose Intoler

2022
Beta cell neogenesis from ducts and phenotypic conversion of residual islet cells in the adult pancreas of glucose intolerant mice induced by selective alloxan perfusion.
    Endocrine journal, 2002, Volume: 49, Issue:5

    Topics: Alloxan; Animals; Cell Differentiation; Cell Division; Glucagon; Glucose Intolerance; Homeobox Prote

2002
Central administration of alloxan impairs glucose tolerance in rats.
    Journal of neural transmission (Vienna, Austria : 1996), 2005, Volume: 112, Issue:10

    Topics: Alloxan; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Disease Models, Animal; Glucose In

2005
Evidence for direct action of alloxan to induce insulin resistance at the cellular level.
    Diabetologia, 1998, Volume: 41, Issue:11

    Topics: Alloxan; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Dogs; Glucose Clamp Technique; Glu

1998